Generated by All in One SEO v5.0.1.1, this is an llms.txt file, used by LLMs to index the site. # dLife Healthcare Private Limited dLife Healthcare Private Limited ## Sitemaps - [XML Sitemap](https://www.elearning.dlife.in/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [Free Keto & LCHF Nutrition Diploma Course In India?](https://www.elearning.dlife.in/articles/free-keto-lchf-nutrition-diploma-course-in-india/) - We’ve all lived long enough to know the answer to that conundrum in the title: There is no such thing! dLife.in’s Diploma in Low Carb Nutrition is a premium product that comes at a cost. Many wise men who went before us have rightly said, “If you think education is expensive, you should try ignorance”. - [Online Low Carb Keto Coach Nutrition Diploma India](https://www.elearning.dlife.in/articles/online-low-carb-keto-coach-nutrition-diploma-india/) - A new decade, a new year, but the same old you? Every New Year, legend holds, is built on the wreckage of millions of New Year resolutions. People the world over, make ambitious decisions to start afresh, go green, get a life… Studies show that most resolutions are history by mid-January (19th to be specific). - [FAQ - Diploma In Low Carb Nutrition](https://www.elearning.dlife.in/articles/faq-diploma-in-low-carb-nutrition/) - Few questions which have been asked repeatedly are being answered on this page: What's the credibility of the course? The certification is from NSDC Partner in India. After completing the course one can do personalized Low Carb Nutrition based health coaching. Everyone who has completed the course are into consulting and active on twitter, and - [Pre-enrollment Steps For 6 Month Diploma In Low Carb Nutrition](https://www.elearning.dlife.in/articles/pre-enrollment-steps-for-6-month-diploma-in-low-carb-nutrition/) - Pre-enrollment is the process when we are taking enrollments for the next month as no more seats are available in the current month. Only 10 seats are available for pre-enrollment and carries 10% discount on fees. Once all the pre-enrollment seats are taken, the discounts will be reduced to 5% maximum Here are the steps: ## Pages - [Home](https://www.elearning.dlife.in/) - Indian Low Carb LCHF & Keto Nutrition Certification Courses. 6 Month Low Carb Keto Diploma Certification from NSDC Partner. Award winning Low Carb Platform - [Low Carb Nutrition & Metabolic Health - Course Review & Rating](https://www.elearning.dlife.in/low-carb-nutrition-metabolic-health-diploma-course-review-rating/) - If you have diabetes, hypertension, PCOS, PCOD, Obesity, and other Metabolic Syndrome, low-carb nutrition is the only way to come off all pills. dLife.in is India's first, the only award-winning, and the world's single largest platform that offers the course on "Low Carb Nutrition & Metabolic Health" that trains you to use Low Carb Nutrition - [Contact Us](https://www.elearning.dlife.in/contact-us/) - Write To UsFor Any Specific Queries on Courses, Affiliate Partnership or Bugs. Your Name (required) Your Email (required) Select Subject —Please choose an option—Pre RegistrationLow Carb Nutrition Advisor CourseAffiliate PartnershipWebsite Bug Your Message Math Captcha 96 ÷ = 32 Certification From NSDC Partner!6-month Low Carb Nutrition Diploma & 3 Month Certificate courses with certification from - [Terms Of Service](https://www.elearning.dlife.in/terms-of-service/) - Copyright Notice © 2020 dlife.in. All rights reserved. Any reproduction, distribution, adaptation, translation, storage, transmission of the contents of this course or dealing with the content in any other way without prior written permission of the owner constitutes an offence in violation of the Copyright act, 1957. Terms of Service The use of this eLearning - [Low Carb Nutrition Courses FAQ](https://www.elearning.dlife.in/low-carb-nutrition-certification-faq/) - The list of questions relating to Low Carb Nutrition courses: Certification Entity The Diploma will be issued by ITRC, Indore. This is a NSDC Partner Certification. The Certificate & the Diploma carries complete legal tenability in India. The certificate will be issued on completion of the batch. CPD certificate will only be made available on - [Certificate & Diploma Issue Details](https://www.elearning.dlife.in/certification/) - CertificationCertificate Courses certification from NSDC Partner in India. As an extension of low carb nutrition certificate and advisor courses, dLife.in the eLearning platform is the technology provider for the certificate and diploma courses on Low Carb Nutrition, starting with the following:Low Carb Nutrition & Metabolic Health Diploma course with a one-month internship on the dLife.in - [Low Carb Nutrition & Metabolic Health Diploma - Payment Plans](https://www.elearning.dlife.in/low-carb-nutrition-metabolic-health-diploma-emi-payment-plan/) - Course Link: https://www.elearning.dlife.in/shop/6-month-low-carb-nutrition-diploma/ 12-month EMI payment plan INR 15000/month paid for 12 months through UPI or online Under this plan the total fee is conveniently spread out into 12 easy EMIs with zero discount 6-month EMI payment plan INR 29100/month paid for six months through UPI or Online. This plan gives you a discount of - [About](https://www.elearning.dlife.in/about/) - About UsSince the August of 2014, we at dLife.in have dedicated our lives to Low Carb High Fat diets for the dietary management of diabetes, obesity, PCOS, NAFLD etc. Our latest venture brings the gift of hope and the promise of well-being to every Diabetic struggling in the dark. dLife.in is the only Award winning - [Privacy Policy](https://www.elearning.dlife.in/privacy-policy/) - Who we are More about us on: https://www.elearning.dlife.in/about/ What personal data we collect and why we collect it Comments When visitors leave comments on the site we collect the data shown in the comments form, and also the visitor’s IP address and browser user agent string to help spam detection. An anonymized string created from - [Purchase Confirmation](https://www.elearning.dlife.in/checkout/purchase-confirmation/) - Thank you for your purchase! 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Please clear your bookmarks in case you are trying to access some old URL. - [My Notes](https://www.elearning.dlife.in/my-notes/) - [Affiliate Terms](https://www.elearning.dlife.in/affiliate-terms/) - Affiliate TermsSignup as affiliate, market our course and earn affiliate credits Anyone can join as affiliate. Affiliate need not be an enrollee in any course. But, every enrollee automatically gets an affiliate account also. Following are the terms :Referral commission will be 10% of the Fees for the course at checkout, excluding taxes if any.The - [Affiliate Area](https://www.elearning.dlife.in/affiliate-area/) - [Details Needed For Payout](https://www.elearning.dlife.in/details-needed-for-payout/) - All payouts will be through NEFT and subject to TDS so the following details will be needed one time. Please fill the form and hit Submit. All fields required. - [Search](https://www.elearning.dlife.in/search/) - Search Results will only be visible to users who have enrolled for the course and are logged in. Others will not see any search results. Search for: - [Quiz Reports](https://www.elearning.dlife.in/quiz-reports/) - [Groups Dashboard](https://www.elearning.dlife.in/groups-dashboard/) - [Shop](https://www.elearning.dlife.in/shop/) ## Products - [Short Term Diploma In Low Carb Nutrition & Metabolic Health](https://www.elearning.dlife.in/shop/6-month-low-carb-nutrition-diploma/) - USDINRUSD If Outside India, please select USD from above. Book a Discovery Call if you have any queries. 6-month course after registering with the NSDC > SkillIndia site. There are 6 tabs lower down on the page covering curriculum, reviews, video reviews, etc. Please check that also. All Course Ratings & Reviews It's self-paced and self-learning, with everything online. There is no traveling required. Enroll and start anytime—lifetime access to the course and updates on the course, subject to TOS. 6 Live lectures from International Guest Faculty -- one per month. Starts from Batch 09. 144 hrs of Live online lectures with Q&A and assignments. Starts from Batch 09. CPDSO UK Accredited Course. 144 CPD hours. Recognised in 50+ countries. Certification through NSDC Partner -- ITRC, Indore -- is for India only. NSDC is a body under MSDE (GOI), so the certificate is legally tenable in India. This certificate can be pulled into the DIGILOCKER Account in real time once issued. Testifies that this is a government-recognised document. After completing the course, you practice as a Metabolic Health Consultant. This is a non-medical wellness coaching diploma certification based on Therapeutic Carb Reduction. It doesn't help diagnose any ailment/disease or prescribe any medicine, and that's best left to medical professionals. Dedicated WhatsApp group for enrollees. Access for 6 months even after completing the course Includes ONE YEAR complimentary access, from the date of enrollment, to the community where the internship assignments will be handled online. Ten-plus years of curated data that includes 250+ Indian success stories + 2000+ Indian LCHF/Keto recipes to refer to when you step out into the professional nutritional consulting world. No other course in the world offers this feature, as only we have a community that deals with real-world cases. Combined success stories of all certified Metabolic Health Coaches/Doctors growing by at least 15000 per year! Estimated beneficiaries in 10+ years of dLife protocol well over 100,000! Award-Winning Indian Low Carb Platform. Also featured in English & Hindi Outlook Magazine of 19th April 2021. - [Short Term Diploma In Low Carb Nutrition & Metabolic Health - Monthly Subscription](https://www.elearning.dlife.in/shop/short-term-diploma-in-low-carb-nutrition-metabolic-health-monthly-subscription/) - Book a Discovery Call if you have any queries. 6-month course after registering with the NSDC > SkillIndia site. There are 6 tabs lower down on the page covering curriculum, reviews, video reviews, etc. Please check that also. All Course Ratings & Reviews It's self-paced and self-learning, with everything online. There is no traveling required. Enroll and start anytime—lifetime access to the course and updates on the course, subject to TOS. 6 Live lectures from International Guest Faculty -- one per month. Starts from Batch 09. 144 hrs of Live online lectures with Q&A and assignments. Starts from Batch 09. CPDSO UK Accredited Course. 144 CPD hours. Recognised in 50+ countries. Certification through NSDC Partner -- ITRC, Indore -- is for India only. NSDC is a body under MSDE (GOI), so the certificate is legally tenable in India. This certificate can be pulled into the DIGILOCKER Account in real time once issued. Testifies that this is a government-recognised document. After completing the course, you practice as a Metabolic Health Consultant. This is a non-medical wellness coaching diploma certification based on Therapeutic Carb Reduction. It doesn't help diagnose any ailment/disease or prescribe any medicine, and that's best left to medical professionals. Dedicated WhatsApp group for enrollees. Access for 6 months even after completing the course Includes ONE YEAR complimentary access, from the date of enrollment, to the community where the internship assignments will be handled online. Ten-plus years of curated data that includes 250+ Indian success stories + 2000+ Indian LCHF/Keto recipes to refer to when you step out into the professional nutritional consulting world. No other course in the world offers this feature, as only we have a community that deals with real-world cases. Combined success stories of all certified Metabolic Health Coaches/Doctors growing by at least 15000 per year! Estimated beneficiaries in 10+ years of dLife protocol well over 100,000! Award-Winning Indian Low Carb Platform. Also featured in English & Hindi Outlook Magazine of 19th April 2021. - [Low Carb Nutrition Certificate - PCOS & Obesity](https://www.elearning.dlife.in/shop/12-week-low-carb-nutrition-certificate-pcos-obesity/) - This CPDSO UK accredited course focuses on Low Carb Nutrition for PCOS & Obesity. The theory is followed by a 2-week internship on the dLife.in community. This combination no other competing service can offer as none have the integration that dLife.in, as the first and only Award-Winning Indian Low Carb Winning platform, has. Even after - [Low Carb Nutrition Certificate - CardioDiabesity](https://www.elearning.dlife.in/shop/12-week-low-carb-nutrition-certificate-diabetes-obesity/) - This CPDSO UK accredited course focuses on Low Carb Nutrition for Obesity and Diabetes. The theory is followed by a 2-week internship on the dLife.in community. This combination no other competing service can offer as none have the integration that dLife.in, as the first and only Award-Winning Indian Low Carb Winning platform, has. The certificate ## Courses - [Short Term Diploma In Low Carb Nutrition & Metabolic Health](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/) - Low carb LCHF KETO Nutrition Diploma with certification from NSDC Partner. Become a certified Keto Coach, Low Carb Nutritionist. No recertification needed. - [Low Carb Nutrition Certificate - PCOS & Obesity](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/) - [Low Carb Nutrition Certificate - CardioDiabesity](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/) ## Lessons - [Cholecystokinin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/cholecystokinin/) - Key Points Introduction Structure of Cholecystokinin Physiological Roles Of Cholecystokinin Factors Controlling Cholecystokinin Production Mechanism Of Cholecystokinin Actions What If Cholecystokinin Is Low? What If Cholecystokinin Is High? Introduction Cholecystokinin (CCK) is a multifaceted hormone that regulates digestive health and appetite. Its actions extend beyond mere digestion, influencing satiety and potentially impacting mood and anxiety. - [Aldosterone](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/aldosterone/) - Key Points: Introduction & Alternate Names Synthesis of Aldosterone What Stimulates The Production of Aldosterone? Functions Of Aldosterone What Happens With Too Much Aldosterone? Causes, diagnosis, and treatment options. What Happens With Too Little Aldosterone? Causes, diagnosis, and treatment options. Testing & Interpretation Of Test Results Aldosterone & LCHF Diet Introduction & Alternate Names Aldosterone - [Learning System Overview](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/learning-system-overview/) - Key points: Navigation flow sequence. Notes taking explained. Quizzes and assignments. Course Materials. Timed Access & completion time. Welcome and congratulations for having signed up for . At this stage, please take time out to complete your profile including first name, last name, display name, address, and other fields. Please remember that the final - [Non Alcoholic Fatty Liver Disease - NAFLD](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/non-alcoholic-fatty-liver-disease-nafld/) - Key Points Introduction Anatomy Of Liver Functions Of Liver Liver Explained! Function, Pathology, Diseases, & Cirrhosis (Video) Liver Function Tests (LFT) - Reference Range Introduction The liver is a vital organ of the body for overall body homeostasis through several biochemical processes and without these functions life cannot be maintained. The human adult liver weighs - [LIPID Peroxidation](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/lipid-peroxidation/) - Key Points Introduction Mechanism of Lipid Peroxidation Products of Lipid Peroxidation Biological Implications LIPID Peroxidation & Ferroptosis Causes Of Lipid Peroxidation Role of anti-oxidants in Lipid-Peroxidation Introduction Lipid peroxidation is a complex biochemical process that leads to the oxidative degradation of lipids, particularly polyunsaturated fatty acids (PUFAs). This process is significant both in biological systems - [Ketogenic Diet & Mental Health](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/ketogenic-diet-mental-health/) - Key Points Introduction Understanding the Problem: A Dual Crisis of Over-Nutrition and Under-Nutrition Medication-Centric Paradigm: A Double-Edged Sword Nutritional and Metabolic Psychiatry: Food as Mental Medicine The Ketogenic Diet: A Transformative Approach Alternatives to Ketogenic Diets Key Takeaways for India The Path Forward: Empowering Change Groundbreaking Research Video (From Metabolic Health Conference 2024) Introduction Mental - [The Role of Exercise](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/the-role-of-exercise/) - Key Points Introduction Seven Benefits Of Exercise Which Exercises & How Much? Diabetics & Blood Sugar Control Blood Pressure & Exercise When To Check With A Doctor? No amount of exercise can cover a BAD DIET. So, it is essential to fix the diet first in case all the advantages of exercising and being active - [Metabolic Disorder -- Current Indian Data](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/metabolic-disorder-current-indian-data/) - Key Points Introduction Obesity Diabetes Insulin Resistance Hypertension Polycystic Ovary Syndrome (PCOS) NAFLD Interconnections Among Metabolic Disorders Conclusion Metabolic disorders, including obesity, diabetes, insulin resistance, hypertension, and polycystic ovary syndrome (PCOS), are increasingly prevalent in India, contributing significantly to the nation's health burden. Obesity Obesity and central obesity are increasingly prevalent in India, posing significant - [Strategies for Self-Promotion](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/strategies-for-self-promotion/) - Key Points Introduction Strategies -- Website What's Necessary on Website Strategies -- Social Media Explain the Scope Of Your Service Final Thoughts Introduction For a successful career, we always should have a good strategy to build good brand value for oneself. Although there's no readymade recipe for success, nothing works better than a word of - [Luteinizing Hormone](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/luteinizing-hormone/) - Key Points Introduction What Is LH Functions of LH What constitutes normal LH levels? When is it appropriate to check LH levels? Relationship between FSH and LH LH Commonly Asked Questions Introduction Luteinizing Hormone (LH) plays a crucial role in the reproductive systems of both men and women. Produced by the pituitary gland, LH levels - [Human Growth Hormone](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-growth-hormone/) - Key Points Introduction Ways To Increase HGH HGH & Metabolism HGH Deficiency and Excess Approved Medical Uses Video Introduction Human growth hormone, or HGH, also called somatotropin, is produced by the pituitary gland and influences multiple areas of the body, primarily to stimulate growth in children. After the growth plates in bones (epiphyses) close, HGH - [Leptin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/leptin/) - Introduction & Alternate Names Functions Of Leptin What Happens With Too Much Leptin? What Causes Leptin Resistance? Reversing Leptin Resistance What Happens With Too Little Leptin? Medical Use Of Leptin & Drug Interactions Video Introduction & Alternate Names Leptin is a hormone secreted from fat cells. It helps in regulating body weight. The name leptin - [Role of Metabolic Therapies in Neurological and Systemic Health](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/role-of-metabolic-therapies-in-neurological-and-systemic-health/) - Key Points Introduction Understanding Metabolic Therapies Neurodegenerative Disorders and Metabolic Therapies Mechanisms of Action Practical Application in India Conclusion Video (from Metabolic Health Conference 2024) Introduction Neurological disorders are among the most challenging health conditions to address, affecting millions of individuals worldwide. Despite advances in pharmacology, many treatments focus on symptom management rather than addressing - [Understanding Autoimmune Conditions, and the Role of Carnivore Diet in Management](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/understanding-autoimmune-conditions-and-the-role-of-carnivore-diet-in-management/) - Key Points Introduction The Nature of Autoimmune Diseases The Problem with Plant-Based Diets The Carnivore Diet as a Solution Indian Context: Managing Autoimmune Diseases Through Diet Practical Applications For Autoimmune Patients Case Study: Crohn’s Disease and Diet Addressing Misconceptions Final Thoughts Video (From Metabolic Health Conference 2024) Introduction Chronic diseases like autoimmune disorders are increasingly - [Understanding Migraines: Causes, Connections, and Management](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/understanding-migraines-causes-connections-and-management/) - Key Points Introduction What Are Migraines? The Link Between Migraines and Metabolic Health How Sodium and ATP Play a Role in Migraines Preventive Strategies Alternative Fuel for the Brain Diagnosis and Monitoring Key Takeaways for Migraine Management Video from Metabolic Health Conference 2024 Introduction Migraines are more than just severe headaches. They are a complex - [Managing LCHF In Social Functions](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/managing-lchf-in-social-functions/) - Key Points: Introduction Skip One More Meal -- OMAD Drain The Glycogen Load With Protein Burn The Carbs Introduction One of the major advantages of LCHF / Keto WOE (way of eating) is that blood sugar levels run within a narrow range. This, in turn, means that insulin levels are also not seeing the wild - [The Metabolic Approach to Cancer: A Holistic and Evolving Paradigm](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/the-metabolic-approach-to-cancer-a-holistic-and-evolving-paradigm/) - Key Points Introduction Understanding the Metabolic Approach to Cancer The Terrain Ten: Comprehensive Cancer Care Key Components of the Metabolic Approach Diet and Fasting: Pillars of Metabolic Health Conclusion Video (From Metabolic Health Conference 2024) Cancer treatment has undergone remarkable advances over the years. However, the persistent challenges of treatment resistance, side effects, and increasing - [Ketogenic Diet & Polycystic Kidney Disease](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/ketogenic-diet-polycystic-kidney-disease/) - Key Points Introduction Ketone Body Metabolism Application of Ketogenic Diet for PKD Video from Metabolic Health Conference 2024 Introduction Polycystic kidney disease (PKD) is a genetic disorder characterized by the formation of numerous cysts in the kidneys, leading to kidney enlargement and impaired function. It is primarily inherited and can manifest in two main forms: autosomal - [Low Carb & Ketogenic Diet For Kidney Disease](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-ketogenic-diet-for-kidney-disease/) - Key Points Introduction Diabetic Kidney Disease Video (from Metabolic Health Conference 2024) Introduction Chronic kidney disease is usually caused by other conditions that put a strain on the kidneys. Often it's the result of a combination of different problems. CKD can be caused by: high blood pressure – over time, this can put a strain on the - [Ketogenic Diet For Alzheimer's Disease](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/ketogenic-diet-for-alzheimers-disease/) - Key Points Introduction Ketone Body Mechanism Key Findings Supporting the Ketogenic Diet's Impact Introduction The ketogenic diet (KD), characterized by high fat and low carbohydrate intake, has garnered interest as a potential dietary intervention for Alzheimer's disease (AD). Research indicates that this diet may influence cognitive function and mitigate some symptoms associated with AD. - [High Intensity Interval Training - HIIT](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/high-intensity-interval-training-hiit/) - Key Points Introduction HIIT Alternate Names HIIT Benefit HIIT for Chronic Diseases Tabata Training Details HIIT In A Fasted State Video Introduction HIIT is a type of interval training exercise. It incorporates several rounds that alternate between several minutes of high-intensity movements to significantly increase the heart rate to at least 80% of one’s maximum - [Excess Post-exercise Oxygen Consumption (EPOC)](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/excess-post-exercise-oxygen-consumption-epoc/) - Key Points Introduction What is EPOC? Factors Influencing EPOC Physiological Effects of EPOC Leveraging EPOC How To Measure EPOC Introduction What happens to your engine at the end of a long car trip? It doesn’t require a degree in automotive engineering to know that once you’ve reached your destination, your car’s engine stays warm as - [Iron Profile Test](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/iron-profile-test/) - Key Points Introduction Components of an Iron Panel Dangers of High Ferritin Managing High Ferritin Levels Introduction An Iron Panel, also known as Iron Studies or Iron Profile, is a set of blood tests that measure different aspects of iron metabolism to assess an individual's iron status. Here's a breakdown of the typical components included - [LIPID Panel TEST (LPT)](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/lipid-panel-test-lpt/) - Key Points Introduction Purpose of Test Components Of LIPID Panel Test Interpreting the Results Risks of High Triglycerides Introduction A lipid panel, also known as a lipid profile, is a blood test that measures the levels of specific lipids in your blood, primarily focusing on cholesterol and triglycerides. This test is essential for evaluating - [Thyroid Function Test (TFT)](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/thyroid-function-test-tft/) - Key Points Introduction Method Of Thyroid Function Testing Key Tests Normal Ranges Interpreting Thyroid Function Test Results Considerations for Interpretation Video Introduction The thyroid gland plays a crucial role in regulating the body's metabolism through the secretion of thyroid hormones—thyroxine (T4) and triiodothyronine (T3). Thyroid function tests (TFTs) are essential for diagnosing thyroid dysfunction, which - [Kidney Function Test (KFT)](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/kidney-function-test-kft/) - Key Points Introduction Common Conditions Affecting Kidney Function Common Symptoms For KFT Types of Kidney Function Tests Interpretation of Results Video Introduction Kidney function tests (KFTs), also known as renal function tests (RFTs), are essential diagnostic tools used to assess the health and functionality of the kidneys. These tests measure various substances in the blood - [Liver Function Test (LFT)](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/liver-function-test-lft/) - Key Points Introduction Purpose of Liver Function Tests Components of Liver Function Tests Acute and Chronic Liver Disorders Drug Use and Toxin Exposure Liver Injury Interpretation of Liver Function Tests Clinical Context Video Introduction Liver Function Tests (LFTs), also known as liver chemistries, are blood tests that provide information about the state of liver health - [Autophagy](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/autophagy/) - Key Points Introduction Different Mechanisms of Autophagy Core Machinery Of Autophagy Insulin Signaling and Autophagy Inhibition Intermittent fasting And Autophagic Response under Pathological Conditions Significance In Medicine Video Introduction Autophagy is a fundamental cellular process that eliminates molecules and subcellular elements, including nucleic acids, proteins, lipids, and organelles, via lysosome-mediated degradation to promote homeostasis, differentiation, - [Complete Blood Count (CBC) Tests](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/complete-blood-count-cbc-tests/) - Key Points Introduction Components of a CBC Impact of Hormones On CBC Inflammatory Markers & CBC Interpretation of CBC Video Introduction A Complete Blood Count (CBC) is a common blood test that evaluates the composition and health of your blood by measuring different components including red blood cells (RBCs), white blood cells (WBCs), and platelets. - [Gut Brain Axis](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/gut-brain-axis/) - Key Points Introduction Anatomy & Physiology of the Gut-Brain Axis Autonomic Nervous System Enteric Nervous System (ENS) Vagus Nerve Gut-Brain Connection Two Part Videos Introduction The concept of the gut-brain axis has garnered significant attention in recent years, highlighting the intricate connections between gastrointestinal (GI) health and neurological functions. The GBA integrates multiple systems including - [Glucose Ketone Index -- GKI -- Guide to Its Usage in Cancer and Other Health Conditions](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/glucose-ketone-index-gki-guide-to-its-usage-in-cancer-and-other-health-conditions/) - Key Points Introduction Understanding the Glucose Ketone Index Calculating Your Own GKI Common Mistakes to Avoid Measuring GKI: The Role of Keto-Mojo Thomas Seyfried and the Role of GKI in Cancer Wrapping Up Introduction The Glucose Ketone Index (GKI) is a valuable metric used to assess metabolic health by examining the relationship between blood glucose and - [Gastrin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/gastrin/) - Key Points Introduction The Three Major Hormones of GI Tract Physiological Roles Of Gastrin Factors Controlling Gastrin Production Effects of Gastrin on Pancreatic Enzyme Secretion What If Gastrin Is Low? What If Gastrin Is High? Introduction Gastrin is a peptide hormone primarily secreted by G cells in the gastric antrum, duodenum, and pancreas. It plays - [Secretin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/secretin/) - Key Points Introduction Structure of Secretin Physiological Roles Of Secretin Factors Controlling Secretin Production Mechanism Of Secretin Actions What If Secretin Is Low? What If Secretin Is High? Introduction In 1902, British physiologists William M. Bayliss and Ernest H. Starling made a groundbreaking discovery: secretin, the first hormone identified, initiating the era of endocrinology. Secretin - [Anabolic Resistance](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/anabolic-resistance/) - Key Points Importance of Muscles What is Anabolic Resistance Factors Contributing to Anabolic Resistance Mechanism Of Anabolic Resistance Nutritional Countermeasures for Anabolic Resistance Lifestyle Countermeasures for Anabolic Resistance Wrapping Up Importance of Muscles Adequate quantity and quality of skeletal muscle mass are vital for overall health and function. In addition to its obvious role in converting chemical - [Background And Current Status](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/background-and-current-history/) - Key Points Introduction Cholesterol Myths Current Status The Statin Trials Focus On Insulin, Inflammation, Stress & Sleep Introduction Nutrition science is continuously evolving ever since Ancel Keys fudged data to come up with the Diet-Heart hypothesis. Then came a similar revelation about the fudged Sydney Diet Heart Study. But, before the revelations came to fore, - [Energy Pathways](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/energy-pathways/) - Key PointsEnergy and its role in the human bodyUnderstanding MetabolismCatabolismAnabolismAmphibolic PathwaysDisorders Of MetabolismEnergy and its role in the human bodyEnergy is the capacity or power to do work. The human body requires a continuous source of energy for any physical and mental activity alongside various systems like digestive, respiratory, circulatory, excretory and control systems, growth, - [Other Popular Diets](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/other-popular-diets/) - Key PointsThe Failed Geometrical ShapesDASH DietMediterranean DietPaleolithic DietSouth Beach DietVegan DietThe Failed Geometrical ShapesThe Standard Dietary Advice from Food Pyramid to MyPlate has been an epic failure. And, the worst part is that no one is willing to take the blame. The experts are still busy blaming those who follow their advice and yet fail - [Low Carb Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-diet/) - Key Points: Loose Definition Why Indians Find Low Carb Difficult? What Next? Low Carb High Fat (LCHF) Diet Ketogenic Diet Atkins Diet Carnivore Diet All the other diets that we looked at in the previous lesson had two things in common: None of them considered Macro distribution as a tool to tweak diet. All of - [Insulin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/) - Key Points Introduction Functions Of Insulin Insulin & Minerals Insulin Resistance Insulin Resistance Linked Disorders Insulin is a polypeptide hormone made by the Islets of Langerhans located in the Pancreatic Beta cells. The molecular formula of human insulin is C257H383N65O77S6. Insulin is a protein composed of two chains, an A chain (with 21 amino acids) and a B - [Vitamins](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/) - Key Points: Introduction Quick Facts On Vitamins Fat-Soluble Vitamins Water-Soluble Vitamins Importance Of Vitamins Introduction Vitamins are organic compounds, and essential micronutrients, that are required in small amounts to sustain life. Each organism has different vitamin requirements. For example, humans need to consume vitamin C or ascorbic acid, but dogs do not. Dogs can produce, - [Minerals](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/) - Key points Introduction Macrominerals Microminerals Introduction Minerals help our bodies develop and function. They are essential for good health. Knowing about different minerals and what they do can help you to make sure you get the adequate supplementation stack designed for your clients. Essential minerals are sometimes divided up into major minerals (macrominerals) and trace - [Supplements](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/) - Key Points:What Are Supplements?Who Needs Food Supplements?Possible Health RisksWhat Are Supplements?The idea behind food supplements, also called dietary or nutritional supplements, is to deliver nutrients that may not be consumed in sufficient quantities. Food supplements include: Vitamins,Minerals,Amino acids,Fatty acids, andOther substances delivered in the form of pills, tablets, capsules, liquid, etc.We have already covered Vitamins - [Carbohydrates](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/carbohydrates/) - Key Points: The Three Types Of Dietary Carbohydrates Functions Of Digestible Carbohydrates Functions Of Fiber What Is Net Carb? Glycemic Index & Glycemic Load Carbohydrate Metabolism Carbs, or carbohydrates, are molecules that have carbon, hydrogen and oxygen atoms. Carbohydrates (CHO) are found in a wide array of both healthy and unhealthy foods. In nutrition, "carbs" - [Proteins](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/proteins/) - Key Points: Introduction Four Levels Of Protein Structure Functions Based Types of Protein Building Blocks - The Twenty Amino Acids Essential Conditionally Essential & Non-Essential Amino Acids Protein Digestion & Assimilation Introduction Proteins are one of the three types of nutrients used as energy sources by the body. Proteins and carbohydrates each provide 4 calories - [Fats](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/fats/) - Key Points Introduction Types Of Fat LIPID Metabolism - Lipolysis, Lipogenesis Introduction Fats are one of the three main macronutrients, along with carbohydrates and proteins. Fats and oils are composed of molecules known as triglycerides that are esters composed of three fatty acid units linked to glycerol. An increase in the percentage of shorter-chain fatty acids and/or unsaturated fatty acids - [Alcohol](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/alcohol/) - Key Points Introduction Common Alcohols & Their Formula Metabolism Of Alcohol Kinetics of Alcohol Elimination Factors Modifying the Alcohol Elimination Rate Alcohol Toxicity Reasons Impact On Health Other Alcohol Facts Introduction Although classified as a depressant, the amount of alcohol consumed determines the type of effect. Alcohol is an organic compound that is characterized by - [Glucagon](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/glucagon/) - Key Points: Introduction & Alternate Names Functions Of Glucagon What Happens With Too Much Glucagon? What Happens With Too Little Glucagon? Glucagon Tests Medical Use Of Glucagon & Drug Interactions Introduction Glucagon is a linear peptide of 29 amino acids and with a molecular weight of 3485 Da. Its primary sequence is almost perfectly conserved - [Thyroid Stimulating Hormone - TSH](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/thyroid/) - Key Points: Introduction & Alternate Names Functions Of TSH How Is TSH Controlled? What Happens With Too Much TSH? What Happens With Too Little TSH? Medical Use Of Thyroid Drugs & Interactions Introduction Thyroid-stimulating hormone is produced by the pituitary gland that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every - [Follicle-stimulating Hormone](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/fsh/) - Key Points: Introduction & Alternate Names Functions Of FSH What Happens With Too Much FSH? What Happens With Too Little FSH? FSH Tests Introduction Follicle-stimulating (FSH) is a member of the glycoprotein hormone family. The family also includes LH, chorionic gonadotropin (CG) and thyroid-stimulating hormone (TSH). These glycoprotein hormones are disulfide-rich heterodimers consisting of non-covalently - [Ghrelin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/ghrelin/) - Key Points: Introduction & Alternate Names Functions Of Ghrelin What Happens With Too Much Ghrelin? What Happens With Too Little Ghrelin? Introduction Ghrelin was discovered after the ghrelin receptor (called growth hormone secretagogue type 1A receptor or GHS-R) was determined in 1999. The hormone name is based on its role as a growth hormone-releasing peptide, with reference - [Human Evolution](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/) - Four Stages Of Human Evolution Human evolution began with the Primates. Primate development diverged from other mammals about 85 million years ago. Various divergences among apes, gibbons, orangutans occurred during this period, with Homini (including early humans and chimpanzees) separating from Gorillini (gorillas) about 8 million years ago. Humans and chimps then separated about 7.5 million years - [Dietary Guidelines Myths & Facts](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/) - Key Points Background The Official Dietary Guidelines Has Anything Changed Over The Years? New Kid In Town Every Five Years CardioDiabesity Is An Epidemic LCHF Revolution Background Over the ages, advice on eating behavior, food choices, and food preparation have been incorporated into philosophical and religious writings. However, in the past 150 years, these recommendations - [Cholesterol & Its Functions](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/functions-in-the-body/) - Key Points:IntroductionDifferent Types OF CholesterolFunctions In CellsBiosynthesis RegulationApolipoproteinsUnits of Measurement & Conversion FormulasCholesterol (C27H46O) is an organic compound that the body requires as a building block for cell membranes and for hormones like estrogen and testosterone. We may associate cholesterol with fatty foods, but most of the waxy substance is made by the liver and - [Test And Numbers & CAC Score](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/test-and-numbers-cac/) - Key Points: The Standard Tests The Standard Limits What's Also To Be Included? LDL Subfraction Test CAC Score Test The Standard Tests "LIPID Profile/Panel Test" is the name of the "profile/panel" that labs use to bundle the standard tests for cholesterol numbers. It is known by many names like Coronary Risk Panel, Lipid Profile, Fasting - [Planning For Transition](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/before-you-begin/) - Key Points: Pre Transition Preparation Pre Transition Data Compiling Few More Things To Consider Forum Access We are sure that by now you would now be ready for interacting with patients/clients looking for hand-holding on LCHF / Ketogenic way of eating. Always remember that in the Indian context, we have demarcated low carb into two - [Diet & Supplements Goal For MetX Syndrome](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diet-meal-planning/) - Key Points Introduction Per Meal Carb Tolerance Primary Dietary Goals Supplementation Goals Recipe Module and Building Diet Plan Diet Plan and Supplementation goals for Sports Nutrition cases have been dealt with in a separate lesson under the Sports Nutrition section. Here we will be focussing exclusively on cases of Metabolic Syndrome -- diabetes, obesity, PCOS, - [Types of Intermittent Fasting](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/types-of-intermittent-fasting/) - Key Points: Introduction The Six Ways Of Intermittent Fasting How To Begin? Tips To Make Intermittent Fasting Work Advantages Of Intermittent Fasting Fasting has been promoted and practiced from antiquity worldwide by physicians, by the founders and followers of many religions, by culturally designated individuals (e.g., hunters or candidates for initiation rites), and by individuals - [Aids And Cautions](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/aids-and-cautions/) - Key PointsIntroductionAids To HelpFew CautionsIntroductionUnless you’re a cheeky midnight snacker, fasting is already incorporated into the daily routine since we fast when we sleep. Sleep is the time when the body regenerates and it can do this because we are still and not giving our bodies any extra demands in addition to what it’s already - [Practical Challenges](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/practical-challenges/) - Key PointsIntroductionChallengesOvercome ChallengesFinal thoughtsIntroductionGetting people to adopt a Carbohydrate Restricted Diet is a big challenge. It’s not as easy. Only those who are pushed against a wall -- meaning those with multiple health issues -- will adopt this. Rest may not be that easy. The addictive potential of carbohydrates is real.ChallengesWe will come across various - [Coaching Skills](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/coaching-skills/) - Key Points:IntroductionClient Expectations Vs Our ExpectationsExplaining LCHF NutritionImportant Questions to ask in different situationsConclusionsIntroductionCoaching skills is an important aspect when we deal with different people in our professional life. Coaching works both ways. We have to be coached upon by others so that we develop the necessary skills. We also have to coach the clients - [How To Cook Low Carb Foods](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/how-to-cook-low-carb-foods/) - Key Points Advanced Glycation End Products (AGE) Cooking and AGEs Vegetarian Cooking Non-Vegetarian Cooking AGEs Inhibitors Advanced Glycation End Products Advanced Glycation End Products (AGE) are a hot topic in nutrition. Dietary advanced glycation end products (dAGEs) are known to contribute to increased oxidative stress and inflammation. These are linked to the recent epidemics of - [Data Capturing](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/data-capturing/) - Key Points Introduction Data to capture How to use the data Conclusion Introduction Biometrics is the technical term for body measurements and calculations. It’s essential to capture some data which can show the progress the client is making. All progress seen in such metrics is a great motivation to the client as well as the - [The Role of Sleep](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/the-role-of-sleep/) - Key Points Introduction What Controls Sleep? Change of Circadian Rhythm Recommended Sleep Duration Effects Of Sleep Deprivation Treatment For Sleep Deprivation Sleep Is Important Introduction Sleep plays a vital role in good health and well-being throughout the span of life. Getting enough quality sleep at the right times can help protect mental health, physical health, - [The Role of Stress Management](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/the-role-of-stress-management/) - Key PointsIntroductionImpact On HealthManaging StressSeeking Professional HelpStress is how the brain and body respond to any demand. Any type of challenges—such as performance at work or school, a significant life change, or a traumatic event—can be stressful. Stress can affect your health. It is important to pay attention to how you deal with minor and - [Medical Tests Before Transitioning](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/medical-tests-before-transitioning/) - Key Points: Necessary Tests Before Suggesting Exercises For Those Who Can Afford Necessary Tests Before beginning the transition to LCHF or Keto diet, the following tests should be done if not done as recently as 30 days before starting: CBC. Cardiac Profile. Inflammation Markers - hsCRP, ESR. ESR normally is part of CBC in many - [Interaction On Forum](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/interaction-on-forum/) - The community forum is the place where you can get all hands-on experience on whatever you have learned in the course. The internship period lasts for one month and during this period you will have to complete all the assignments attached to this lesson and the next lesson. Your community forum account will be active - [Recipe & Diet Plan Posting](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/recipe-diet-plan-posting/) - This is part of the one-month internship. Here's the help documentation on Recipe Posting component of dLife FoodLog system: dLife FoodLog : Recipes Module - How to (you will need an account on https://www.dlife.in/forums which is separate from eLearning account. So, if not already signed up till now, please do so and we will activate it - [Diabetes Medications](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/) - Key Points Introduction Diabetes Medication Types Medications, of course, is something that the licensed medical practitioner will handle and as a nutritionist, you are not expected to be talking about medicines. However, while switching a client from the usual high carb low-fat diet to a low carb diet, you will have to keep in mind - [Weight Loss Medications](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/weight-loss-medications/) - Key Points: Introduction Different Drugs & Adverse Effects Bariatric Surgery Conclusion Introduction Obesity is a serious medical condition that leads to high blood pressure, high cholesterols and heart diseases. Loss of sleep, consumption of excess junk food, physical inactiveness are major causes of obesity. According to the World Health Organization (WHO), around 13% of the - [Hypertension Medications](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/) - Key Points Introduction Hypertensive Crisis Anti-Hypertensive Medications Introduction Anti-Hypertensive medications are those pharmaceutical drugs that reduce Blood pressure in the case of those who have elevated levels. Blood pressure is the pressure of circulating blood on the walls of blood vessels. Most of this pressure is due to work done by the heart by pumping - [Melatonin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/melatonin/) - Key Points: Introduction & Alternate Names Functions Of Melatonin How Is Melatonin Controlled? What Happens With Too Much Melatonin? What Happens With Too Little Melatonin? Medical Use Of Melatonin & Drug Interactions Introduction Melatonin is a hormone secreted by the enigmatic pineal gland in response to darkness. It is a hormone that regulates the sleep-wake cycle and is known - [Adrenaline](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/adrenaline/) - Key Points: Introduction & Alternate Names Functions Of Adrenaline What Happens With Too Much Adrenaline? What Happens With Too Little Adrenaline? Adrenal Fatigue -- Is It Real? Adrenal Insufficiency How to Control Adrenaline? Medical Use Of Adrenaline & Drug Interactions Introduction Adrenaline, a hormone (and also a drug), is produced in the medulla in the - [Cortisol](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/cortisol/) - Key Points: Introduction & Alternate Names Functions Of Cortisol What Happens With Too Much Cortisol? What Happens With Too Little Cortisol? Cortisol Tests How to Control Cortisol? Medical Use Of Hydrocortisone & Drug Interactions Introduction Cortisol formula is C21H30O5 and has a molar mass, 362.460 g/mol. Cortisol is a steroid hormone produced by the adrenal - [Norepinephrine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/norepinephrine/) - Key Points: Introduction & Alternate Names Functions Of Norepinephrine How Is Norepinephrine Controlled? What Happens With Too Much Norepinephrine? What Happens With Too Little Norepinephrine? Medical Use Of Norepinephrine & Drug Interactions Introduction Norepinephrine, also called noradrenaline or noradrenalin, is a naturally occurring chemical in the body that acts as both a stress hormone and - [The Role Of Nutrition In Human Health](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/the-role-of-nutrition-in-human-health/) - Key Points: Introduction Nourishment Disease Risk Treating Disease Medicinal Foods Nutritional Deficiencies & Supplements Bottom Line Introduction “Food is Medicine” is a term that was coined by Hippocrates, the father of Western medicine. He believed that eating wholesome food is the basis for good health. Fueled by a healthy diet, the body is more resilient. - [Introduction To Anthropometry](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/introduction-2/) - Key Points Introduction The History of Anthropometry Modern-Day Use Ideal Body Weight Body Mass Index Waist To Hip Ratio Waist Circumference Waist To Height Ratio Introduction Anthropometry, or anthropometrics, is the study of human body measurements. At its most basic form, anthropometrics is used to help scientists and anthropologists understand physical variations among humans. Anthropometrics - [Body Fat Measurement](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/body-fat-measurement/) - Key Points Introduction Densitometry Bod Pod Skinfold caliper Bioelectrical impedance analysis DEXA scan Introduction Measuring Fat is necessary to achieve a healthy body composition. Bad body composition means more fat & less muscle. This situation lead to lots of health issues that are plaguing a lot of the world's population. Indians have a high carbohydrate - [Managing LCHF While Travelling](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/managing-lchf-while-travelling/) - Key Points Introduction Short Journeys & Long Journeys Eating out in a Restaurant Business Tour / Holiday Few Images From Travel Kit Introduction Traveling is a real challenge for Low carb meals. There is a good chance of falling off the wagon if the correct food is not available. A good way to beating this - [Foods: The 'Yes', 'May' & 'Never' List](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/foods-yes-may-never-list/) - Key Points: 56 Names For Sugar Sugar Is Toxic Sugar Is Not About Just Added Sugar Sugar is a master of disguise and goes by a slew of different names. This makes it easy for the food industry to hide the amount of sugar in various products. Just because you don’t see “sugar” on the - [Food Intolerance & Allergy](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/food-intolerance-allergy/) - Key Points: Food Intolerance Food Allergy Anaphylaxis Common Allergy Triggers Food Poisoning Food allergy and food intolerance are commonly confused as there's an overlap between the symptoms of the two. Food Intolerance (Sensitivities) Food intolerances are not life-threatening, by and large. Food intolerance is a chemical reaction that some people have after eating or drinking - [The Origin Of Carbohydrate Restriction In Chronic Diseases](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/the-origin-of-carbohydrate-restriction-in-chronic-diseases/) - Documents dating back to the late 1700s show that carbohydrate restrictions for conditions like obesity & diabetes have existed in the past. In this lesson, all such dietary approaches centering around carbohydrate restriction will be listed to show that Low Carb High Fat (LCHF) diet is not a new phenomenon. On the contrary, it has - [Research, Monograph & Books on LCHF & Keto](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/published-lchf-keto-research/) - Key Points: Systematic Reviews/Meta-analyses (22 publications, by date) Randomised Controlled Trials (45 publications by date) Other Trials (17 publications, by date) Review papers (15 publications, by date) Monographies and other books (16 items, by author) Materials Section - RCT Summary LCHF Vs HCLF Diets When you begin your practice, there will be many ill-informed naysayers - [Introduction To Sports Nutrition](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/introduction-to-sports-nutrition-2/) - Key Points: Introduction What About Others? But Isn't Sports Nutritional Needs Different? Benefits Of Sports Nutrition Flexibility Realism & Consistency Is The Key Ketogenic Diet & Sports Nutrition Bottom Line The last 25 years have witnessed an enormous interest in sports nutrition. In order to boost the physiological and psychological development, you need to synchronize - [mTOR Pathway](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/mtor-pathway/) - Key PointsIntroductionActivation of mTOR and role of LeucineRole of Insulin and irrelevance of carbohydratesMeal frequency and mTOR activationmTOR and chronic diseasesIntroductionThe mammalian target of rapamycin or the mTOR pathway is a part of a complex network of cell signaling and transduction. It is part of the phosphatidylinositol 3-kinase (PI3K) pathway, a family of lipid kinases - [AMPK Pathway](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/ampk-pathway/) - Key PointsIntroductionActivation of the AMPK PathwayFunctions of the AMPK PathwayAMPK Activation & its Benefits For Athletic PerformanceUsing the mTOR and AMPK Pathways For Maximal Performance OutcomesAMPK and Chronic DiseasesIntroductionThe human body loves to maintain homeostasis no matter what. There is an opposing function for every pathway and hormones in the body. For example, insulin and - [Water & Electrolytes](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/water-electrolytes/) - Key Points:Water & Its FunctionsElectrolytes & Its FunctionsChloride & Its FunctionsElectrolyte DisordersTreating Electrolyte DisordersWater & Its FunctionsWater is an essential nutrient and plays a key role in the human body. We can survive up to several weeks without food, but only a few days without water. Every system in the body, from cells and tissues, - [Inflammation](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/inflammation/) - Key Points: Introduction Diseases & Disorders Are Related Inflammatory Response Causes Of Inflammation Why athletes are prone to inflammation Foods that reduce inflammation Introduction Inflammation is a complex fabric of signals and cellular responses from our immune system that enables our bodies to recognize and respond to infection and injury. Having too weak of an - [Diet And Supplement Planning Goals](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diet-and-supplement-planning-goals/) - Key Points Introduction Vitamins & Minerals Supplements Diet and Supplementation goals for metabolic syndrome disorders have been covered in a separate lesson later. Between the two goals, there will be overlap but still we preferred to dedicate a lesson for each. The macro targets for weight loss and muscle gain have been covered in topics - [Fructose](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/fructose/) - Key Points Introduction Fructose Metabolism In Brief Health Implications Of Fructose Bottom Line Introduction Although there is some uncertainty about the mechanisms of fructose absorption, most of the fructose seems to be absorbed by facilitated transport in the jejunum by the fructose transporter GLUT5. The body has limited capacity to absorb pure fructose, and intake - [Push Exercise](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/push-exercise/) - The following schedule is based on the six PULL and PUSH exercises that have been posted in the course and is meant for a beginner: Day -1 (Push) Squats - 3x12 Lunges- 3x15 Bench Press- 3x 15 Bench - 3x15 Tricep Variation 1- 3x15 Tricep Variation 2- 3x15 Day 2 (Cardio) Any form of cardiovascular - [Pull Exercise](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/pull-exercise/) - When a Human being consumes its species-appropriate diet overtime that Human reaches his optimal health. This results in many positive changes physiologically and psychologically. One of the changes in the vigor and vitality of the body. This vigor and vitality can be taken to a new optimal level through the addition of exercise. Hence exercise - [Reading Nutrition Labels](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/reading-nutrition-labels/) - Key PointsIntroductionList of Ingredients Is ImportantSugar can be in many different namesList Of AdditivesConclusionIntroductionIn the Low carb world, we restrict many foods & additives which are proven to be harmful for health or are known to be controversial. We also have to know the alternative names of harmful ingredients. Sometimes the nutrition labels can be - [Adipose Tissue](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/adipose-tissue/) - Key Points: Introduction Adipose Tissue Composition Adipose Tissue Location Adipose Tissue Endocrine Function The Battle For Brown Fat - Benjamin Bikman Video Who Is At Risk Of Getting Obese? Introduction Adipose tissue is a lipid-storing type of loose connective tissue. Also called fat tissue, adipose is composed primarily of adipose cells or adipocytes. While adipose tissue can - [Obesity Is A Metabolic Disorder](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/obesity-is-a-metabolic-disorder/) - Key Points: Introduction Mechanism Of Getting Obese At what stage, obesity starts to show problematic symptoms? Increased Cell Size as a Predictor of Systemic Insulin Sensitivity HyperTrophy Hypoxia & Inflammation Prof. Robert Lustig - The three faces of metabolic syndrome Introduction Obesity is an enlargement of adipose tissue to store excess energy intake. To handle - [Peptide YY](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/peptide-yy/) - Introduction & Alternate Names Functions Of Peptide YY What Happens With Too Much Peptide YY? What Happens With Too Little Peptide YY? Introduction & Alternate Names First isolated in 1983, Peptide YY is a gastrointestinal hormone consisting of 36 amino acids with tyrosine residues at both C and N-terminals from which it derives its name - [Incretin -- GLP-1 And GIP](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/incretin-glp-gip/) - Introduction Glucagon-Like Peptide 1 Gastric Inhibitory Polypeptide Over 100years have passed since the discovery of the incretin concept, which later opened up the possibility of a novel therapy in the treatment of diabetes. Inspired by Bayliss and Starling’s discovery of secretin in 1902, Moore et al. hypothesized that gut extracts contain a hormone that regulates the endocrine pancreas, - [Adiponectin](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/adiponectin/) - Introduction & Alternate Names Functions Of Adiponectin What Happens With Too Much Adiponectin? What Happens With Too Little Adiponectin? Adiponectin-Leptin Relation Drugs That Increase Adiponectin How to increase adiponectin naturally Introduction & Alternate Names Adiponectin (also referred to as GBP-28, apM1, AdipoQ, and Acrp30) is a protein hormone and adipokine, which is involved in regulating - [Progesterone](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/progesterone/) - Introduction & Alternate Names Functions Of Progesterone What Happens With Too Much Progesterone? What Happens With Too Little Progesterone? Risks & Side Effects Of Using Synthetic Progesterone (Progestins) Progesterone is an endogenous steroid that belongs to the group of steroid hormones called the progestogens and is the major progestogen in the body. It is secreted - [Oestrogen Or Estrogen](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/oestrogen/) - Introduction & Alternate Names Functions Of Oestrogen What Happens With Too Much Oestrogen? What Happens With Too Little Oestrogen? Risks & Side Effects Of Using Synthetic Oestrogen Introduction & Alternate Names Oestrogen or Estrogen is one of two main sex hormones that women have. The other one is progesterone. Estrogen is responsible for female physical - [Obesity Inflammation & Comorbidities](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/obesity-comorbidities/) - Key Points: Introduction What Is Inflammation? Obesity and Inflammation Inflammation in Metabolically Healthy Obese Consequences of Low-grade Inflammation Symptoms of Chronic Inflammation Inflammatory Lab Markers The global epidemic of obesity is accompanied by an increased prevalence of metabolic syndromes, in particular diabetes, hypertension, and cardiovascular disease. The major cause of these disorders associated with obesity - [TOFI - Thin Outside Fat Inside - Obesity](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/tofi-thin-outside-fat-inside/) - Key Points: Introduction Thin Outside Fat Inside (TOFI) The Problem With BMI Classifying As TOFI -- How-To Who Is At Risk of Being TOFI? Health Risks Of TOFI How To Lose Visceral Fat? Personal Fat Threshold -- Amy Berger Introduction You probably have heard people bragging, “I’m so lucky, I can eat anything junky, sugary, - [PCOS - Polycystic Ovarian Syndrome](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/pcos-polycystic-ovarian-syndrome/) - Key Points Introduction The Two Criteria For Diagnosis Types Of PCOS How PCOS Impacts You Polycystic ovary syndrome, or PCOS, was first reported by Stein and Leventhal in 1935, described as symptoms complex with amenorrhea, hirsutism, and enlarged ovaries with multiple cysts. The prevalence of PCOS is highly variable ranging from 2.2% to 26% - [Vitamins Minerals & Supplements For PCOS & Obesity](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/vitamins-minerals-supplements-for-pcos/) - [Vitamins Minerals & Supplements For CardioDiabesity](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/vitamins-minerals-supplements-for-cardiodiabesity/) - [Cardiovascular Disease - CVD](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/cardiovascular-disease/) - Key Points: Introduction Types of Cardiovascular Disease Signs & Symptoms Risk Factors Diagnosing Cardiovascular Disease Introduction It would be worthwhile to have a detailed graphic of heart anatomy included so that one can understand clearly whenever there's any reference to the heart anatomy components. A self-explanatory diagram is as in fig 1 below: Here's - [Diabetes](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/diabetes/) - Key Points: Introduction Blood Sugar Regulation Type 1 Diabetes Type 2 Diabetes Gestational Diabetes Impaired glucose tolerance and impaired fasting glycemia Ideal Blood Sugar Targets What Is A1C? Introduction In the Insulin Resistance & Diabetes topic, we have touched briefly on everything that will be covered in greater detail in this lesson and topics within - [Amylin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/amylin/) - Key Points Introduction Physiological Effects Amylin Analog Treatment Introduction Since its discovery in 1986, the hormone known as amylin has been the subject of extensive research that has ultimately translated into the approved diabetes drug pramlintide acetate (Symlin; AstraZeneca, Wilmington, DE). Amylin is a 37-amino-acid peptide glucoregulatory hormone that is co-secreted with insulin from the pancreatic - [Somatostatin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/somatostatin/) - Key Points Introduction Physiological Effects What happens if too much somatostatin? What happens if too little somatostatin? Pharmacologic Uses of Somatostatin Introduction Somatostatin was first discovered in hypothalamic extracts and identified as a hormone that inhibited the secretion of growth hormones. Subsequently, somatostatin was found to be secreted by a broad range of tissues, including ## Topics - [LIPID Peroxidation & Cardiovascular Disease (CVD)](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/lipid-peroxidation/topic/lipid-peroxidation-cardio-vascular-disease-cvd/) - Key Points Introduction Role in Atherosclerosis Mechanisms of Lipid Peroxidation in Atherosclerosis Mechanisms of Endothelial Cell Injury Influence of Lipid Peroxides on Neutrophil Adhesion and Activation Reducing Lipid Peroxidation Video Introduction Lipid peroxidation (LPO) is a biochemical process involving the oxidative degradation of lipids, leading to the formation of reactive oxygen species (ROS) and various - [Type 2 Diabetes](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/diabetes/topic/type-2-diabetes/) - Key Points: Introduction Classification Of Type 2 Diabetes Who Are At Risk? What Are The Symptoms? What Causes Type 2 Diabetes? How To Manage Type 2 Diabetes? How To Lower Chances Of Getting Type 2 diabetes? Introduction Type 2 diabetes, the most common type of diabetes, is a disease that occurs when your blood glucose, - [Vitamin D](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/vitamin-d/) - Key Points: Introduction Metabolism In Brief How Much Vitamin D Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Vitamin D is a fat-soluble vitamin. In humans, the most important compounds in this group are vitamin D3 (also known as cholecalciferol) and vitamin D2 (ergocalciferol). Very few foods in nature contain vitamin D. The flesh - [Niacin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/niacin/) - Key Points: Introduction Metabolism In Brief How Much Niacin Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Niacin (also known as vitamin B3, nicotinic acid -- pyridine-3-carboxylic acid, nicotinamide -- niacinamide or pyridine-3-carboxamide) is one of the water-soluble B vitamins and derivatives include nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate - [LIPID Peroxidation & Neurological Disorders](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/lipid-peroxidation/topic/lipid-peroxidation-neurological-disorders/) - Key Points Introduction Association with Specific Neurological Disorders Mechanisms of Lipid Peroxidation in Parkinson's Disease Mechanisms of LPO In Alzheimer's Disease Treatment & Mitigation Video (from Metabolic Health Conference 2024) Introduction Lipid peroxidation (LPO) is a critical process in the pathogenesis of various neurological disorders, characterized by the oxidative degradation of lipids, particularly polyunsaturated fatty - [Vitamin C](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/vitamin-c/) - Key Points: Introduction Metabolism In Brief How Much Vitamin C Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Update 2024 Introduction Vitamin C, also known as L-ascorbic acid or simply ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, and is also available as a dietary supplement. Its formula - [The Atkins Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-diet/topic/atkins-diet/) - Key Points: The Four Phases Of Atkins Diet Modified Atkins Diet Foods Allowed On Atkins Diet Foods Not Allowed On Atkins Diet Controversies & Clinical Significance Applicability In The Indian Context This diet, though not looking at macros, emphasizes the word low carb, and primarily was a weight loss diet. This diet was promoted by - [FODMAP Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/other-popular-diets/topic/fodmap-diet/) - Key Points Introduction What Are FODMAPs? Who Should Follow the FODMAP Diet? Benefits of the FODMAP Diet Phases of the Low-FODMAP Diet Foods to Include and Avoid Challenges and Considerations Wrapping Up Introduction The FODMAP diet is a dietary approach primarily designed to help individuals with Irritable Bowel Syndrome (IBS) and other digestive disorders manage their symptoms. FODMAP - [dLife Case Story - Atrial Fibrillation (AFib) & Hypertension](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/cardiovascular-disease/topic/dlife-case-story-atrial-fibrillation-afib-hypertension/) - This is a dLife success story case of one with AFib+Hypertension Watch this 33-minute video from start to finish before you can mark this topic complete. [ld_video] - [Mediterranean Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/other-popular-diets/topic/mediterranean-diet/) - Key Points Background Dietary Components Beverages Low Carb Mediterranean Diet Mediterranean Diet Studies Background Mediterranean diet is a generic term based on the typical eating habits in the countries that border the Mediterranean Sea. Since there are many countries -- 16 on the last count -- that come into the picture, there is no ONE - [Calcium Channel Blockers or Calcium Antagonists](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/topic/calcium-channel-blockers-or-calcium-antagonists/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Brands -- Generics FDA Warnings Introduction Calcium channel blockers, or calcium antagonists are a group of medications that disrupt the movement of calcium through calcium channels. Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with - [Magnesium](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/magnesium/) - Key Points: Introduction Metabolism In Brief How Much Magnesium Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Magnesium, an abundant mineral in the body, is naturally present in many foods, added to other food products, available as a dietary supplement and is also present in some medicines (such as antacids and laxatives). - [Calcium](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/calcium/) - Key Points: Introduction Metabolism In Brief How Much Calcium Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Calcium is a mineral that is necessary for life. In addition to building bones and keeping them healthy, calcium enables our blood to clot, our muscles to contract, and our heart to beat. Calcium also helps carry - [Folate](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/folate/) - Key Points: Introduction Metabolism In Brief How Much Folate Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Folate is a water-soluble B vitamin that is naturally present in some foods, added to others, and available as a dietary supplement. This vitamin was also known as "folacin" earlier. Vitamin B9 is the generic - [Pantothenic Acid](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/pantothenic-acid/) - Key Points: Introduction Metabolism In Brief How Much Pantothenic Acid Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Vitamin B5 is also known as pantothenic acid or Pantothenate. The word pantothenic comes from the Greek "pantou," meaning everywhere. Nearly all foods contain small quantities of pantothenic acid. Vitamin B5 is a water-soluble - [Riboflavin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/riboflavin/) - Key Points: Introduction Metabolism In Brief How Much Riboflavin Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Riboflavin (also known as vitamin B2) is one of the B vitamins naturally present in some foods, added to some food products, and available as a dietary supplement. This vitamin is an essential component of - [Thiamine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/thiamine/) - Key Points: Introduction Metabolism In Brief How Much Thiamine Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Thiamin (or thiamine) is one of the water-soluble B vitamins. It is also known as vitamin B1. This vitamin plays a vital role in energy metabolism and, therefore, in the growth, development, and functioning of - [Vitamin B12](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/vitamin-b12/) - Key Points: Introduction Metabolism In Brief How Much Vitamin B12 Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Vitamin B12 is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and a prescription medication. It exists in several forms and contains the - [Vitamin B6](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/vitamin-b6/) - Key Points: Introduction Metabolism In Brief How Much Vitamin B6 Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Vitamin B6 is a water-soluble vitamin that is naturally present in many food items. The body needs vitamin B6 for over 100 enzyme reactions involved in metabolism, mostly concerned with protein metabolism. Vitamin B6 - [Vitamin K](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/vitamin-k/) - Key Points: Introduction Metabolism In Brief How Much Vitamin K Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Update 2024 Introduction “Vitamin K,” is the generic name for a family of compounds with a common chemical structure of 2-methyl-1,4-naphthoquinone, is a fat-soluble vitamin. It is present in many food items and also available - [Vitamin E](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/vitamin-e/) - Key Points: Introduction Metabolism In Brief How Much Vitamin E Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Vitamin E (Tocopherols) is the collective name for a group of fat-soluble compounds with distinctive antioxidant activities. Naturally occurring vitamin E exists in eight chemical forms (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, - [Vitamin A](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/vitamin-a/) - Key Points: Introduction Metabolism In Brief How Much Vitamin A Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Vitamin A is a fat-soluble vitamin that is naturally present in many food items. Vitamin A is important for normal vision, the immune system, and reproduction. It also assists the functioning heart, lungs, kidneys, - [Carnivore Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-diet/topic/carnivore-diet/) - Key Points: What Is Carnivore Diet? What Is On The Allowed List? What's On The No List? Who It Is Not For? Applicability In The India Context Update in 2024 Dr. Shawn Baker is the unofficial Carnivore King. His book -- The Carnivore Diet -- was published in 2018. This 52+-year-old trained orthopedic surgeon and - [The Randle Cycle: Understanding the Glucose-Fatty Acid Cycle](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/energy-pathways/topic/the-randle-cycle-understanding-the-glucose-fatty-acid-cycle/) - Key Points Introduction Mechanism of the Randle Cycle Key Enzymes in the Randle Cycle Mechanisms of Insulin Resistance Linked to the Randle Cycle Introduction The Randle Cycle, also known as the glucose-fatty acid cycle, describes the reciprocal regulation of carbohydrate and fatty acid oxidation in muscle and other tissues. This type of cycle must not - [Sugar & Carb Addiction](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/the-role-of-nutrition-in-human-health/topic/sugar-carb-addiction/) - Key Points Introduction Why Sugar Is Addictive? High Glycemic Index Carbohydrates and Food Addiction How To Conquer Carb & Sugar Cravings? The diagnostic construct of “food addiction” is a highly controversial subject. However, studies have shown characteristics of other addictions in relationship to food, such as effects on the brain reward system, impaired control, risky - [LIPID Peroxidation & Diabetes](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/lipid-peroxidation/topic/lipid-peroxidation-diabetes/) - Key Points Introduction Role of Lipid Peroxidation in Diabetes Complications of Diabetes Mediated by Lipid Peroxidation Management and Treatment Evidence has consistently shown a significant correlation between poor blood sugar management, increased production of lipid oxidation byproducts, and worsening metabolic health in individuals with diabetes. There is a distinct connection between diminished antioxidant activity within - [Protease](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/topic/protease/) - Key Points Introduction Types of Protease Biological Roles Industrial Applications Clinical Applications Food Sources Of Proteases Introduction Protease (PR), proteinase, or peptidase refers to a group of proteolytic enzymes whose major function is to catalyze the hydrolysis of peptide bonds that link amino acids together in a polypeptide chain with high sequence selectivity and catalytic - [Amylase](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/topic/amylase/) - Key Points Introduction Types of Amylase Biological Roles Mechanism of Action Optimal pH for Amylase Activity Importance in Digestion Clinical Implications Industrial and Biotechnological Applications Research and Future Directions Conclusion Introduction Amylase plays a pivotal role in the digestion of carbohydrates, breaking down complex polysaccharides into simpler, absorbable forms. Found mainly in the saliva and - [Lipase](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/topic/lipase/) - Key Points Introduction Types of Lipases Structure and Function Biological Roles Industrial Applications Clinical Implications Conditions Leading to High Lipase Levels Conditions Leading to Low Lipase Levels Role of the Gallbladder in Lipase Function Possible Interactions of Lipase Supplements Introduction Lipase is a crucial enzyme that catalyzes the hydrolysis of triglycerides into free fatty acids - [Insulin Resistance, Lipotoxicity & Energy Toxicity](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/adipose-tissue/topic/insulin-resistance-lipotoxicity-energy-toxicity/) - Key Points What is energy toxicity? What is Lipotoxicity? Athlete’s Paradox Normal Insulin Signaling Lipids that cause insulin resistance Mechanism Distinction between lipotoxicity and energy toxicity Consequences of chronic lipotoxicity What is energy toxicity? Energy toxicity refers to a metabolic state characterized by the accumulation of excess energy, primarily stored as triglycerides in muscle and - [CoQ10](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/coq10/) - Key Points Introduction Benefits Of Taking CoQ10 Side Effects Of Taking CoQ10 Use Of CoQ10 By dLife.in Members Interaction With Drugs Introduction Chemical Formula: C59H90O4 Molar Mass: 863.365 g·mol−1 Coenzyme Q10 (CoQ10) is an antioxidant that your body produces naturally. Your cells use CoQ10 for growth and maintenance. Levels of CoQ10 in your body decrease as you age. CoQ10 levels - [Whey Protein](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/whey-protein/) - Key Points Introduction Types Of Whey Protein Benefits Of Taking Whey Protein Plant Protein vs. whey How To Take? Side Effects Of Taking Whey Protein Use Of Whey By dLife.in Members Drug Interactions Introduction Milk is made of two proteins, casein, and whey. Whey is the liquid remaining after milk has been curdled and strained. - [L Citrulline](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/l-citrulline/) - Key Points: Introduction Benefits of taking Citrulline Types of Citrulline Dosage of Citrulline Side effects of taking Citrulline Final Note Introduction Citrulline is produced in the human body as a byproduct of the enzymatic production of nitric oxide from the amino acid arginine, catalyzed by nitric oxide synthase. It is an α-amino acid and the - [Ashwagandha](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/ashwagandha/) - Key Points Introduction Benefits Of Taking Ashwagandha Side Effects Of Taking Ashwagandha Use Of Ashwagandha By dLife.in Members Interaction With Drugs Ashwagandha (Withania somnifera) is an herb used in Ayurveda, the traditional medicine of India. Its root has a horsey smell (in Sanskrit, ashva means “horse” and gandha means “smell”) and is said to confer the strength and virility - [Myth: Dietary Fat Causes Weight Gain](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/dietary-guidelines-myths-facts/topic/myth-dietary-fat-causes-weight-gain/) - Key Point: Introduction Calorie In Calorie Out Model Of Obesity. So What's The Alternate Model? Factors Driving Obesity Introduction Obesity is one of the biggest health problems in the world. The trend of increase in obesity has been highlighted later in the course in Insulin Resistance & Obesity topic. So, we won't be touching upon - [History of Agriculture](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/topic/history-of-agriculture/) - Key Points: Pre Agriculture Era Agriculture Evolution Start Of Wheat Cultivation Wheat Production In India Wheat For Bread Pre Agriculture Era It has been proven beyond doubt that the primary food consumed by humans was meat. Archaeologists have found evidence dating back over 3 million years that shows humans exclusively consumed meat – with the - [Navigation Flow Sequence](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/learning-system-overview/topic/navigation-flow-sequence/) - Key points:Focus mode interface explained.Lessons/Topics and Reference Material.Marking steps complete.Here you get familiar with the actual course interface and navigation. Focus Mode Interface As you see in figure 1 below, the entire screen inventory is dedicated to only the course content and every other site navigation menu item has been removed. This, essentially removes all - [Notes Taking Explained](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/learning-system-overview/topic/notes-taking-explained/) - Key points:Take Notes ScreenTaking NotesNotes listViewing & Editing NotesTaking notes in classroom environment education is very common. The same concept is extended to e-Learning platform with a difference -- you take notes and save, edit, update them online -- it is completely paperless. You can even download your notes anytime that you like to.Take Notes - [Quizzes and Assignments](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/learning-system-overview/topic/quizzes-and-assignments/) - Key Points: Quiz Quiz retake attempts. Assignments. Assignment retake attempts. Syllabus of quiz/assignments. There will be quiz and assignments spread throughout the course so that you can evaluate your own progress. All the quizzes and assignments are mostly auto-graded except for where it is specifically mentioned that the grading will be by instructors. The scores - [Timed Access & Course Completion Time](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/learning-system-overview/topic/timed-access-completion-time/) - Key Points: Content Dripping. Timed Quiz and Navigation Flow. Assignments Auto Approved. Course Completion Time Limitations. Lessons & Topics With Video. There are many learning platforms that offer courses. Some of them offer certificates or diplomas that have no legal tenability in India. Most of them run on the premise of a collection of audio, - [Course Materials](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/learning-system-overview/topic/course-materials/) - Key points:Must Read Course MaterialsOptional Course MaterialsWe touched upon course materials in the following topic of the current lesson, as a brief overview of the navigation point of view: Navigation Flow Sequence.In the Quizzes & Assignments topic under the current lesson, there was a mention of Must Read lesson/topic materials. Recapping, the course "Materials" can - [Vegan Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/other-popular-diets/topic/vegan-diet/) - Key PointsIntroductionDifference Between Vegetarian & VeganWhat Do Vegans Eat?Nutritional Deficiencies RisksLCHF Vs Vegan Diet Comparison In DiabeticsIntroductionVeganism is more akin to a religious cult than a diet. The origin of this diet goes back to the Seventh Day Adventist Church belief system. It is a diet that excludes anything and everything from animal origins. So, - [South Beach Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/other-popular-diets/topic/south-beach-diet/) - Key PointsIntroductionThe Three PhasesPhase 1: Kickstarting Weight LossPhase 2: Achieving Target WeightPhase 3: Lifestyle Tweaks For Maintaining WeightA typical day's menu on the South Beach DietIntroductionThe South Beach Diet is a commercial diet plan that a cardiologist Dr. Arthur Agatston and dietitian Marie Almon designed in the mid-1990s. This diet was initially designed for cardiovascular - [DASH Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/other-popular-diets/topic/dash-diet/) - Key Points:BackgroundOne Week Plan Of DASH DietPutting The Pieces Of DASH Jigsaw Puzzle TogetherDASH Diet & Sodium IntakeDASH Diet & Weight LossHigher FAT DASH Diet TrialBackgroundDASH is an acronym for Dietary Approaches to Stop Hypertension, and the diet is called DASH Diet. This is promoted by the U.S.-based National Heart, Lung, and Blood Institute to - [Paleolithic Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/other-popular-diets/topic/paleo-diet/) - Key PointsIntroductionWhat Did Our Prehistoric Ancestors Eat?What Paleolithic Dieters Actually Eat?Clinical SignificancePaleo in Indian ContextIntroductionThe Paleolithic diet, or the Paleo diet, in short, is known by other such names as the caveman diet, or stone-age diet. The concept of a Paleolithic diet started in the 1970s. In 2002, a book by Loren Cordain -- The - [LCHF Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-diet/topic/lchf-diet/) - Key Points:Setting The Limit On Daily Carbs IntakeProteins & Fats on LCHF DietWhat About Fiber?Per Meal CHO ToleranceLCHF and Ketogenic Cannot Be Used InterchangeablyNormally, the liver's glycogen storage capacity is around 120 gm. This is the number that becomes the basis for defining Low Carb High Fat (LCHF diet) to begin with. And, then tweak - [Ketogenic Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-diet/topic/ketogenic-diet/) - Key Points:Contra-indicationsThe Three States Of KetosisOrigin & Types Of Ketogenic DietApplicability In The Indian ContextA ketogenic diet is a subset of the LOW CARB HIGH FAT (LCHF) diet. The primary focus here is to first achieve the state of Nutritional Ketosis (NK).Contra-indicationsThe ketogenic diet is contraindicated in patients with the following health conditions:Pyruvate carboxylase deficiencyPorphyriaFat - [Biotin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/topic/biotin/) - Key Points: Introduction Metabolism In Brief How Much Biotin Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Biotin, also known as Vitamin H, is one of the B complex vitamins. It is an essential nutrient that is naturally present in some foods and available as a dietary supplement as well. It is - [Adenosine Triphosphate - ATP](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/energy-pathways/topic/atp/) - Key Points:IntroductionHow ATP Produces EnergyMetabolic Reactions Involving ATPATP In The CellExtracellular ATPAdenosine triphosphate (ATP) is a nucleotide consisting of an adenine base attached to a ribose sugar, which is attached to three phosphate groups. These three phosphate groups are linked to one another by two high-energy bonds called phosphoanhydride bonds, as shown in the figure - [ATP-PC Energy System](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/energy-pathways/topic/phosphagen-system-atp-pc-system-crp-atp-system/) - Key Points:IntroductionWhat is CreatineATP-PC Energy SystemExact Mechanism Of ATP-PC Energy SystemRest Is Important In ATP-PC SystemSupplementationIntroduction A bird's eye view of the three energy systems in a tabular form: [table id=11 responsive=scroll responsive_breakpoint="device" /] Combine the table above with the image below and you would get a clearer understanding of the role of the three - [Lactic Acid Energy System](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/energy-pathways/topic/glycolysis-anaerobic-glycolysis-system-lactic-acid-system/) - Key Points:IntroductionWhat is GlycolysisTen Steps of GlycolysisLactic Acid Energy System In Human ActivityList Of Enzymes Involved in Lactic Acid Energy SystemIntroduction Before we begin, we get the same Table and image from the previous topic for better clarity and continuity of the deliberations. In the previous topic, we discussed the first column of the table - [Aerobic Energy System](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/energy-pathways/topic/aerobic-system/) - Aerobic Energy SystemIntroductionWhat is Aerobic Energy System?ATP production in Aerobic PathwayAerobic Pathway for GlucoseAmino acid PathwayGluconeogenesisFatty Acid PathwayIntroductionNutrients follow a complex pathway from ingestion through anabolism and catabolism to energy production as shown in the figure below: What is Aerobic Energy System?In the presence of oxygen, the Aerobic Energy system produces a large number - [Krebs Cycle](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/energy-pathways/topic/krebs-cycle/) - Key Points: What is the Krebs Cycle? Key Functions Citric Acid Cycle Chemical Reaction Processes In Kreb's Cycle Key Functions What is the Krebs Cycle? The Krebs cycle was discovered by Sir Hans Krebs. He was awarded the Nobel Prize in 1953 for this discovery. It is also called the citric acidity cycle, and the - [Three States Of Ketosis](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/energy-pathways/topic/three-states-of-ketosis/) - Key Points:Ketogenesis the metabolic pathwayRegulation of KetogenesisKeto TerminologyNutritional ketosisStarvation KetosisDiabetic Ketoacidosis – The Dangerous StateKetogenesis the metabolic pathwayKetogenesis is a metabolic pathway that produces ketone bodies, which provide an alternative form of energy for the body. The body is constantly producing small amounts of ketone bodies that can make 22 ATP each in normal circumstances, - [Phosphorus](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/phosphorus/) - Key Points: Introduction Metabolism In Brief How Much Phosphorus Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Phosphorus is the second most plentiful mineral in your body after calcium. Phosphorus and phosphate irons play critical roles in bone structure and essential cellular functions. Dietary phosphorus is absorbed predominantly in the small intestine. - [Sulfur](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/sulfur/) - Key Points: Introduction Metabolism In Brief How Much Sulfur Is Needed? Deficiency Risks Introduction Sulfur, after calcium and phosphorus, is the most abundant mineral element found in our body. It is available to us in our diets, derived almost exclusively from proteins, and yet only 2 of the 20 amino acids normally present in proteins - [Copper](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/copper/) - Key Points: Introduction Metabolism In Brief How Much Copper Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Copper is a trace mineral that is part of several enzymes and proteins that are essential for the adequate use of iron by the body. It is naturally present in some foods and is available - [Zinc](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/ziinc/) - Key Points: Introduction Metabolism In Brief How Much Zinc Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Zinc is involved in numerous aspects of cellular metabolism. It is required for the catalytic activity of approximately 100 enzymes and it plays a role in: immune function, protein synthesis, wound healing, DNA synthesis, and - [Iron](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/iron/) - Key Points: Introduction Metabolism In Brief How Much Iron Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Iron is a mineral that is naturally present in many foods, added to some food products, and available as a dietary supplement. Dietary iron has two main forms: heme and nonheme. Plants and iron-fortified foods - [Manganese](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/manganese/) - Key Points: Introduction Metabolism In Brief How Much Manganese Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Manganese is an essential trace element that is naturally present in many foods and available as a dietary supplement. The human body contains about 10 to 20 mg manganese, of which 25% to 40% is - [Iodine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/iodine/) - Key Points: Introduction Metabolism In Brief How Much Iodine Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Iodine is an essential component of the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroid hormones regulate many important biochemical reactions, including protein synthesis and enzymatic activity, and are critical determinants of metabolic activity. They - [Selenium](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/selenium/) - Key Points: Introduction Metabolism In Brief How Much Selenium Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Selenium is an essential trace mineral that is important for many bodily processes, including cognitive function, a healthy immune system, and fertility in both men and women. It is present in human tissue, mostly in - [Molybdenum](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/molybdenum/) - Key Points: Introduction Metabolism In Brief How Much Molybdenum Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction You may not have heard of the trace mineral molybdenum, but it is essential to your health. Though your body only needs tiny amounts, it's a key component of many vital functions. Without it, deadly - [Chromium](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/topic/chromium/) - Key Points: Introduction Metabolism In Brief How Much Chromium Is Needed? Can Excess Be Toxic? Deficiency Risks Drug Interactions Introduction Chromium is one of the trace minerals needed in very small amounts by the body. It cannot be made in the body and must be obtained from the diet or supplements, although its mechanisms of - [Insulin Resistance & Diabetes](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-diabetes/) - Key Points: Types Of Diabetes Role Of Insulin Resistance In Type 2 Diabetes. What Should Be The Ideal Blood Sugar To Aim For? Damages Of High Blood Sugar Types Of Diabetes Type 1: Type 1 diabetes is a condition in which your immune system destroys insulin-making cells in your pancreas. These are called beta cells. The condition is usually diagnosed - [Insulin Resistance & Cardiovascular Disease](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-cardiovascular-disease/) - Key Points Introduction Insulin Resistance & Myocardium Insulin Resistance & Atherosclerosis Introduction During insulin resistance, several metabolic alterations induce the development of cardiovascular disease. For instance, insulin resistance can induce an imbalance in glucose metabolism that generates chronic hyperglycemia. This, in turn, triggers oxidative stress and causes an inflammatory response that leads to cell damage. - [Insulin Resistance & Cancer](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-cancer/) - Key Points Introduction Insulin Resistance & Obesity Is Associated With Cancer mTOR signaling & Cancer IGF1 and cancer Get The Insulin Levels Down Obesity has been associated with an increased risk of esophageal cancer, pancreatic cancer, colorectal cancer, breast cancer (among postmenopausal women), endometrial cancer, kidney cancer, thyroid cancer, liver cancer, and gallbladder cancer. And, - [Insulin Resistance & PCOS](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-pcos/) - Key Points: Definition and stats Symptoms and diagnosis PCOS and Insulin Resistance Definition and stats PCOS, usually pronounced “pee-kos” (like “peacock” but with the “ck” sound as the end replaced by “sss”) stands for PolyCystic Ovarian Syndrome. It’s the most common endocrine condition in women during their reproductive years and it affects up to a - [Insulin Resistance & Hypothyroidism](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-hypothyroidism/) - Key Points Introduction Diabetes and Thyroid Dysfunction Conclusion Introduction There are three mechanisms of insulin resistance: pre-receptor, receptor, and post-receptor. The current ‘gold standard’ in the assessment of insulin sensitivity is the determination of tissue glucose utilization using the metabolic clamp technique. When it comes to the relation between Thyroid (TSH hormone) and insulin resistance, - [Insulin Resistance & Hypertension](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-hypertension/) - Key Points Introduction Insulin Resistance & Hypertension Insulin Resistance & Plasma Aldosterone Insulin is an anabolic hormone that plays an important role in the regulation of glucose, lipid homeostasis, and energy storage through its metabolic effects on classic insulin-responsive tissues. Insulin resistance, or diminished insulin sensitivity, is a key feature of metabolic syndrome, linking obesity, - [Insulin Resistance & Osteoarthritis](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-osteoarthritis/) - Key Points: Insulin Resistance & osteoarthritis Insulin Resistance & Rheumatoid Arthritis Insulin Resistance & osteoarthritis The metabolic syndrome, which has insulin resistance as its central feature, includes 3 or more of the following factors: hypertension, increased triglycerides, reduced HDL-cholesterol, increased waist circumference, and elevated fasting glucose. Increasing numbers of metabolic syndrome components predict an increased - [Insulin Resistance & NAFLD](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-nafld/) - Key Points: What Is NAFLD What Is Lipotoxicity Lipotoxicity, Insulin Resistance & Inflammation Reversing Fatty Liver (NAFLD) What Is NAFLD Non-alcoholic fatty liver disease (NAFLD) is a very common disorder and refers to a group of conditions where there is an accumulation of excess fat in the liver of people who drink little or no - [Insulin Resistance & Uric Acid](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-uric-acid/) - Key Points Introduction Insulin Resistance & Uric Acid Final Words Introduction Uric acid (UA), a heterocyclic compound of carbon, nitrogen, oxygen, and hydrogen with the formula C₅H₄N₄O₃ and molar mass of 168.112 g/mol. It is a natural waste product from the digestion of foods that contain purines. Purines are normally produced in the body and - [Insulin Resistance & Dyslipidemia](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-dyslipidemia/) - Key Points: What is Dyslipidemia? Insulin Resistance & Dyslipidemia Insulin Resistance Dyslipidemia Solution What Is Dyslipidemia Dyslipidemia occurs when someone has abnormal levels of lipids in their blood. While the term describes a wide range of conditions, the most common forms of dyslipidemia involve: high levels of low-density lipoproteins (LDL), or bad cholesterol low levels of - [Insulin Resistance & Endothelial Dysfunction](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-endothelial-dysfunction/) - Key Points: Endothelium Insulin Resistance & Impaired Nitric Oxide Synthesis Endothelial Dysfunction & Diseases The endothelium is a thin membrane that lines the inside of the heart and blood vessels. Endothelial cells release substances that control vascular relaxation and contraction as well as enzymes that control blood clotting, immune function, and platelet (a colorless substance in the blood) adhesion. The integrity - [Insulin Test - Setting The Bar Right](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-setting-the-bar-right/) - Key Points: Fasting Insulin Lab Values Joesph Kraft Insulin Assay Redefining The Fasting Insulin Limit An insulin blood test, also referred to as the fasting insulin test, is used to measure the amount of insulin in the body. It is also used to monitor the treatment of abnormal insulin levels and also to monitor insulin - [How Humans Evolved](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/topic/how-humans-evolved/) - Key Points Introduction Humans Are Primates Different Species Of Early Humans Modern Human Species Dietary Evolution Where Are We Now? Introduction Human evolution is the gradual process of change by virtue of which people originated from apelike ancestors. Scientific evidence indicates that the physical and behavioral traits shared by all people originated from apelike ancestors. - [The Rise of Modern Chronic Diseases](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/topic/the-rise-of-modern-chronic-diseases/) - Key Points As It Stands In The U.S. & Developed World Burden Of Chronic Disease Developing World Is Not Spared Too India & China In Middle Of CardioDiabesity Crisis Questions That Need Answers As It Stands In The U.S. & Developed World A chronic condition “is a physical or mental health condition that lasts more - [The Current Situation](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/topic/the-current-situation/) - Key Points:Hyper-palatable Food Is One Big CursePOP A Pill Culture To Mask EpidemicMedical Bills Are RisingLow Fat Processed Food Means Sugar LoadedHumans Are OmnivoresVeganism - A Newer Avatar of Low Fat DietStanding At The Cross RoadsGoing Back To Old DaysThe Solution Going ForwardHyper-palatable Food Is One Big CurseThe new-gen wants to enjoy hyper-palatable ultra-processed junk - [The Introduction to Dietary Guidelines.](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/the-introduction-of-dietary-guidelines/) - Key Points:The EventThe First Dietary GuidelineThe Ignored FlawsHow The Guidelines Performed?The Dietary Guidelines for Americans has been published jointly every 5 years since 1980 by the Department of Health and Human Services (HHS) and the Department of Agriculture (USDA). Prior to 1980, USDA had been publishing "Food Guides" from time to time. The entire chronology - [How The Dietary Guidelines Evolved](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/how-the-dietary-guidelines-kept-evolving/) - Key Points:1916 to 1930s: Food for Young Children and How to Select Food1940's: A Guide to Good Eating (Basic Seven)1956 to 1970s: Food for Fitness, A Daily Food Guide (Basic Four)1979: Hassle-Free Daily Food Guide1984: Food Wheel: A Pattern for Daily Food Choices1992: Food Guide Pyramid2005: MyPyramid Food Guidance System2011: MyPlateThe evolution of the United - [The Latest Eat Lancet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/the-latest-eat-lancet/) - Key PointsIntroductionWhat Is Eat Lancet?Tie Up With FSSAIThe Implications & the hidden agendaSo, we have seen how colossal failure the dietary guidelines based on High Carb-Low Fat diet has been. The SDA Church has influenced dietary preachings based on their belief system and not science. SDA church and Coca-Cola and other food companies created a - [Glutamine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/glutamine/) - Key Points Introduction Facts On Taking Glutamine Side Effects Of Taking Glutamine Use Of Glutamine By dLife.in Members Interaction With Drugs Introduction Glutamine is an α-amino acid that affects the processes of growth and function of cells in the stomach and intestines. It is used in the biosynthesis of proteins. Its side chain is similar - [Collagen](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/collagen/) - Key Points Introduction Collagen Boosters Collagen Busters Benefits Of Taking Collagen Side Effects Of Taking Collagen Use Of Collagen By dLife.in Members Interaction With Drugs Introduction Collagen is the main structural protein in the extracellular matrix in the various connective tissues in the body. As the main component of connective tissue, it is the most - [Gelatin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/gelatin/) - Key Points Introduction Benefits Of Taking Gelatin Side Effects Of Taking Gelatin Use Of Gelatin By dLife.in Members Interaction With Drugs Introduction Gelatin (98–99% protein) is derived from collagen, the most plentiful protein in humans and animals. A type of protein derived from partial hydrolysis of collagen, gelatin is found in animal parts that provide us with - [Alpha Lipoic Acid](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/alpha-lipoic-acid/) - Key PointsIntroductionBenefits Of Taking Alpha Lipoic AcidSide Effects Of Taking Alpha Lipoic AcidUse Of Alpha Lipoic Acid By dLife.in MembersInteraction With DrugsIntroductionAlpha Lipoic Acid, also known as α-lipoic acid, lipoic acid, and thioctic acid, is an organosulfur compound derived from caprylic acid. It has a Chemical Formula: C8H14O2S2 and Molecular Weight: 206.32 g·mol−1.ALA is made in - [Omega 3 Fatty Acids](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/omega-3/) - Key Points Introduction Benefits Of Taking Omega 3 Side Effects Of Taking Omega 3 Use Of Omega 3 By dLife.in Members Interaction With Drugs Introduction Omega-3 fats are a key family of polyunsaturated fats. There are three main omega-3s: Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) come mainly from fish, so they are sometimes called - [Flaxseed Oil](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/flaxseed-oil/) - Key Points Introduction Benefits Of Taking Flaxseed Oil (FSO) Side Effects Of Taking Flaxseed Oil Use Of Flaxseed Oil By dLife.in Members Interaction With Drugs Bottom Line Introduction Flaxseed oil comes from ripened flaxseeds that manufacturers have cold pressed to extract the oil. Another name for flaxseed oil is linseed oil. Flaxseed oil contains plant-based - [Curcumin / Turmeric](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/curcumin/) - Key Points Introduction Benefits Of Taking Curcumin Side Effects Of Taking Curcumin Use Of Curcumin By dLife.in Members Interaction With Drugs Introduction Turmeric, a spice that has long been recognized for its medicinal properties, has received interest from both the medical/scientific world and from culinary enthusiasts, as it is the major source of the polyphenol - [Berberine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/berberine/) - Key Points Introduction Benefits Of Taking Berberine Side Effects Of Taking Berberine Use Of Berberine By dLife.in Members Interaction With Drugs Introduction Molecular Formula: C20H18NO4+ Molecular Weight: 336.366 g/mol Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids. It is found in such plants as Berberis (e.g. Berberis vulgaris – barberry, Berberis aristata – tree turmeric, Mahonia aquifolium – Oregon-grape, Hydrastis canadensis – goldenseal, Xanthorhiza simplicissima – yellowroot, Phellodendron amurense - [L Theanine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/l-theanine/) - Key Points Introduction Benefits Of Taking L Theanine Side Effects Of Taking L Theanine Interaction With Drugs & Supplements Introduction L-theanine is an amino acid that is found in tea leaves. It was identified in tea by Japanese scientists in 1949. While tea is the most common dietary source for L-theanine, this compound is also - [MCT Oils](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/mct-oils/) - Key Points Introduction Metabolism Of MCTs Benefits Of Taking MCTs Side Effects Of Taking MCTs Use Of MCTs By dLife.in Members Introduction MCT oil is a dietary supplement that is made up of MCT fats, which are fats that can be found in coconut oil, palm kernel oil, and dairy products. MCT oil is mainly - [Glucosamine, Chondroitin, MSM Plus Hyaluronic Acid](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/glucosamine-chondroitin-msm-plus-hyaluronic-acid/) - Key Points Introduction & Benefits Side Effects Of Taking Glucosamine, Chondroitin, MSM Plus Hyaluronic Acid Use Of Glucosamine, Chondroitin, MSM Plus Hyaluronic Acid By dLife.in Members Interaction With Drugs Introduction & Benefits Those suffering from osteoarthritis suffer from knee pain & swelling. The cartilage in the knee degenerates & hence the knee bones brush against - [Undenatured Collagen UC -II](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/undenatured-collagen-uc-ii/) - Key Points Introduction Alternate Names Benefits Of Taking Undenatured Collagen UC -II Side Effects Of Taking Undenatured Collagen UC -II Interaction With Drugs Introduction Collagen supplements are taken in one of two different forms, either in the form of hydrolyzed collagen or in the form of an undenatured type II collagen; both forms have different dosing strategies and - [Resistant Starch](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/resistant-starch/) - Key Points Introduction Benefits Of Taking Resistant Starch Side Effects Of Taking Resistant Starch Use Of Resistant Starch By dLife.in Members Introduction Resistant starch is a carbohydrate that resists digestion in the small intestine and ferments in the large intestine. As the fibers ferment they act as a prebiotic and feed the good bacteria in the - [Silymarin / Milk Thistle](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/silymarin-milk-thistle/) - Key Points Introduction Benefits Of Taking Silymarin / Milk Thistle Side Effects Of Taking Silymarin / Milk Thistle Use Of Silymarin / Milk Thistle By dLife.in Members Interaction With Drugs Introduction Silymarin is a flavonoid derived from Silybum marianum, a plant commonly known as milk thistle. It is arguably the most commonly used medication for various liver diseases. Silibinin, - [L Leucine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/l-leucine/) - Key Points Introduction Benefits Of Taking L Leucine Side Effects Of Taking L Leucine Use Of L Leucine By dLife.in Members Leucine Facts IsoLeucine -- Isomer of Leucine Introduction L-leucine is the L-enantiomer of leucine. Leucine is one of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many - [Astaxanthin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/astaxanthin/) - Key Points Introduction Benefits Of Taking Astaxanthin Side Effects Of Taking Astaxanthin Use Of Astaxanthin By dLife.in Members Interaction With Drugs Introduction Molar mass: 596.841 g/mol Formula: C40H52O4 Astaxanthin (pronounced "asta-ZAN-thin") is a naturally-occurring carotenoid found in algae, shrimp, lobster, crab, and salmon. Carotenoids are pigment colors that occur in nature and support good health. Beta carotene, for - [L Lysine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/l-lysine/) - Key Points Introduction Benefits Of Taking L Lysine Side Effects Of Taking L Lysine Use Of L Lysine By dLife.in Members Interaction With Drugs Introduction Other names Lysine, D-lysine, L-lysine, LYS, h-Lys-OH Chemical Formula: C6H14N2O2 Molecular Weight: 146.190 g·mol−1 L-lysine is an essential amino acid. Normal requirements for lysine have been found to be about 8 - [Egg Shell Membrane](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/egg-shell-membrane-caps/) - Key Points Introduction Benefits Of Taking Egg Shell Membrane Side Effects Of Taking Egg Shell Membrane Introduction An eggshell is the hard, outer covering of an egg. It consists mostly of calcium carbonate, a common form of calcium. The rest is made up of protein and other minerals. Eggshells are roughly 40% calcium, with each gram - [Cinnamon](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/cinnamon-powder/) - Key Points Introduction Benefits Of Taking Cinnamon Side Effects Of Taking Cinnamon Interaction With Drugs Introduction Cinnamon has been known from remote antiquity. It was imported to Egypt as early as 2000 BC, but those who reported that it had come from China had confused it with cinnamon cassia, a related species. Cinnamon (/ˈsɪnəmən/ SIN-ə-mən) is a spice obtained - [Exogenous Ketones](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/exogenous-ketones/) - Key Points Introduction Benefits Of Taking Exogenous Ketones Side Effects Of Taking Exogenous Ketones Use Of Exogenous Ketones By dLife.in Members Introduction The ketogenic diet, also called the keto diet, is a diet that is high in fat and very low in carbohydrates. Aim of the keto diet is Nutritional Ketosis 24X7, in which the - [Sulfonylureas and Meglitinides](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/topic/sulfonylureas-and-meglitinides/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Brands Generics FDA Warnings Introduction Sulfonylureas and Meglitinides (glinides) have a very similar mode of action which is why they are grouped together here. Sulfonylureas are the first oral antidiabetic agents and can be divided into several generations. Tolbutamide, acetohexamide belongs to the first - [Biguanides](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/topic/biguanides/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Brands Generics FDA Warnings Introduction The term biguanide -- organic compound with the formula HN(C(NH)NH₂)₂ -- refers to a group of oral type 2 diabetes drugs that work by preventing the production of glucose in the liver, improving the body's sensitivity towards insulin and - [Dipeptidyl peptidase-4 - DPP4 - Inhibitors](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/topic/dipeptidyl-peptidase-4-dpp4-inhibitors/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Brands Generics FDA Warnings Introduction Dipeptidyl peptidase 4 (DPP-4) inhibitors are a class of medicine that lower high blood glucose levels and may be used in the treatment of type 2 diabetes. DPP-4 inhibitors slow the inactivation and degradation of GLP-1, a hormone involved in glucose removal from - [Sodium-Glucose Cotransporter-2 - SGLT2 - Inhibitors](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/topic/sodium-glucose-cotransporter-2-sglt2-inhibitors/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Brands Generics FDA Warnings Introduction Sodium-Glucose Cotransporter-2 Inhibitors have been used in the treatment of Diabetes Type 2 since 2013. Mode Of Action SGLT-2 inhibitors are a novel class of anti-diabetic agents that act by inhibiting glucose reabsorption in proximal convoluted tubules of the - [Exogenous Insulin](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/topic/exogenous-insulin/) - Key Points Basal Or Long-Acting Insulin Rapid & Short-Acting Insulin Dosing of Rapid or Short-Acting Insulin Basal Or Long-Acting Insulin Correct dosage of basal insulins to keep your blood sugar level even when not eating will make your life easier as you don’t have to worry about skipping a meal or delay in meals. Here's - [Why LCHF Diet Works For Diabesity Management](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-diet/topic/why-lchf-diet-works-for-disease-management/) - Key Points:Diet Composition & Gastric EmptyingSimplified AssumptionsLooking At The DELTACovering DELTA With ActivityInsulin Needs ComparisonWhy Six To Eight Meals Is Suggestion Is A Waste?Satiety & Weight LossDiabesity: Umbrella Term For Epidemic Of Diabetes + Obesity Combined.Diet Composition & Gastric EmptyingThe image below (source) shows the gastric emptying (GE) time for 3 different combinations. Although not - [American Diabetes Assn - Low Carb & Very Low Carb Diet For Diabetes](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/american-diabetes-assn-low-carb-very-low-carb-diet-for-diabetes/) - Key Points:IntroductionSurprise TurnaroundADA LOW CARB Is Not Really LOW CARBGoing ForwardIntroductionThe American Diabetes Association (ADA) is a U.S.-based nonprofit that seeks to educate the public about diabetes and to help those affected by it by funding research to manage, cure and prevent diabetes. In 2016, the ADA's total revenue was $171 million. (Source: Wikipedia) This - [Thiazolidinediones](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/topic/thiazolidinediones/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Brands Generics FDA Warnings Introduction The Thiazolidinediones (Glitazones) have been around since early 2000. Mode Of Action TZDs decrease insulin resistance by the formation of new fat cells, primarily on arms, thighs, and butt. They target the PPAR-gamma receptor, which activates a number of - [Alpha Glucosidase Inhibitors](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/topic/alpha-glucosidase-inhibitors/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Brands Generics FDA Warnings Introduction The first alpha-glucosidase inhibitor to get FDA approval in the USA was Acarbose in 1995. Miglitol followed in 1999. Voglibose is the latest addition. Mode Of Action Alpha-glucosidase inhibitors slow down the digestion and absorption of carbohydrates by blocking - [Human Digestive System](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/human-evolution/topic/human-digestive-system/) - Key Points: What is the digestive system? Why is digestion important? How does the digestive system work? How does food move through the GI tract? How does the digestive system break food into small parts for use by the body? What happens to the digested food? How does the body control the digestive process? Enzymes - [The Easy Transition Plan](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/before-you-begin/topic/the-easy-transition-plan/) - Key Points Introduction Three Week Transitioning to LCHF Transitioning from LCHF to Keto Important Threads On The Community Introduction Your probable clients could be from one of the following cases: Somone healthy who wants to switch to LCHF / KETO WOE (way of eating). Someone (healthy or metabolically deranged) who tried LCHF / Keto on - [Common Client Questions](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/before-you-begin/topic/common-client-questions/) - Key Points: Introduction Pre Transition Client Questions Client Questions -- Transition Blues Client Question -- Shopping List Client Questions -- Product Brands Client Questions -- Macros and Others Introduction Experience is the best teacher. dLife.in community started on the 21st of August 2014 and over the years there have been many questions that a newly - [L Proline](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/l-proline/) - Introduction Benefits Of Taking L Proline Side Effects Of Taking L Proline Interaction With Drugs Introduction L-proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Proline is sometimes called an imino acid. Proline was first isolated in 1900 by Richard Willstätter who obtained the amino acid while studying - [Myth: Carbohydrates Are Essential](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/myth-carbohydrates-are-essential/) - Key Points:The Three MacronutrientsMetabolic Profile Of Different Parts Of Human BodyWhat's The Theoretical Minimum Intake Need For Carbohydrates?Current Carbohydrate RecommendationsBottom LineThe Three MacronutrientsHuman food intake can broadly be classified into two groups -- Macronutrients & Micronutrients. The three macronutrients are -- carbohydrates, proteins & fats whereas micronutrients (vitamins, minerals, and other food supplements can run - [Myth: Plant Based Diets Are The Best](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/myth-plant-based-diets-are-the-best/) - Key Points: Vegetarian Is Not Same As Vegan Seventh-Day Adventist Church Agenda Plant-Based Has Lot Of Toxin/Anti Nutrient Load Nutritional Deficiency Real-World Data Comparision dLife.in Podcast: Belinda Fettke On Who Is Behind Plant-Based Messaging in Nutrition. Bottom Line Vegetarian Is Not Same As Vegan Vegetarians come in several flavors. Ovo-vegetarians eat eggs, Lacto-vegetarians eat dairy - [Myth: Proteins Cause Kidney Damage](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/myth-proteins-cause-kidney-damage/) - Key Points:The General BeliefOptimal Protein IntakeBusting The Myth - 2018 Published Meta-AnalysisAll Other Safety StudiesWord Of CautionThe General BeliefIt’s a concept that’s been around for at least 50 years and you hear it all the time: higher protein diets cause kidney disease. Consuming excess protein only harms the kidneys if you have underlying kidney or liver - [Myth: Saturated Fat Causes Heart Disease](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/myth-saturated-fat-causes-heart-disease/) - Key Points Vilification By The PUFA Vegetable Oil Industry Ancel Keys Study The Minnesota Coronary Experiment (MCE) Sydney Diet Heart Study Other Studies On Saturated Fat And Conclusions Dr. Paul Mason Video Nina Teicholz Podcast With dLife.in Bottom Line Vilification By The PUFA Vegetable Oil Industry Vilification of Saturated FAT started by Proctor & Gamble - [Diet Heart Hypothesis](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/diet-heart-hypothesis/) - Key PointsIntroductionThe Ancel Keys StudyRe-evaluation of the Ancel Keys Diet-heart HypothesisBut The Industry & Associations Were Already On The JobThe Toxic Trans FatBottom LineThe diet-heart hypothesis [1] postulates that reducing dietary saturated fat reduces serum cholesterol, thereby reducing the risk of cardiovascular disease. Today, this concept has been transformed from a hypothesis into public health - [Myth: PUFA Loaded Vegetable Oils Are Better Than Saturated Fat](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/dietary-guidelines-myths-facts/topic/myth-polyunsaturated-fatty-acids-n6-pufa-oils-are-good/) - Key Points: Introduction Rancidity of PUFAs Is The Problem How Toxic Are OxLAMS? Omega 6:Omega 3 Ratio Omega 6 loaded Poly Unsaturated Fatty Acids (PUFA) vegetable oils are touted to be great. However, ever since these industrial vegetable oils have become part of the diet, health has taken a hit. There are many companies in - [Three Pillars Of Fitness](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/introduction-to-sports-nutrition-2/topic/three-pillars-of-fitness/) - Key Points Introduction The Three Pillars Of Fitness The Neglected Pillars Of Fitness Bottom Line Introduction When you’re striving to lose weight and achieve better health through nutrition, exercise can expedite and help you maintain your results. The other class of enthusiasts is the ones who want bulging arms and six-pack abs. This is precisely - [Importance Of Protein & Fat In Sports](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/introduction-to-sports-nutrition-2/topic/importance-of-protein-fat-in-sports/) - Key Points:Nutritional MisconceptionsProteins & Fats - Essential MacronutrientsSo What About Carbs?Nutritional MisconceptionsWhile there are misconceptions when it comes to training, one that takes mantle for most misconceptions is nutrition. Every now and then we see a new superfood and supplement coming in the market with the promise of enhancing performance and whatnot. Religious beliefs, flawed - [Importance of Hydration](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/water-electrolytes/topic/importance-of-hydration/) - Key Points:IntroductionWater & ExerciseWeight LossAnti-agingCauses Of DehydrationIntroductionWater represents on average 60% of body weight in adult men. However, this percentage decreases along with lean body mass. Most of the organs and tissues contain more than 70% water: blood and kidneys consist of 83% water, and muscles 76% water. However, adipose tissue contains only 10% of - [Dehydration & Sodium Importance in Sports](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/water-electrolytes/topic/dehydration-sodium-importance-in-sports/) - Key Points: Introduction Low Carb Diets And Hydration Effects Of Dehydration Sodium, The Unsung Hero Can sodium increase strength? Salt and factor of fitness Introduction Dehydration can turn into an athlete’s worst nightmare. Optimal athletic performance is dependent upon vitamins, minerals, rest, and adequate hydration, besides training of course. In particular, hydration can be an - [Weight Loss](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diet-and-supplement-planning-goals/topic/weight-loss/) - Key PointsIntroductionFat Loss CasesMacronutrient TargetsWeight StallMacro & Micro Of Food ItemsIntroductionIdeal body weight and other anthropometric details have been covered in a separate section under two lessonsIntroduction To AnthropometryBody Fat MeasurementSo, all the acronyms used here are the same as in the above lessons and we will not be repeating the same here.Fat Loss CasesCurrent - [Muscle Gain](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diet-and-supplement-planning-goals/topic/muscle-gain/) - Key PointsIntroductionMacronutrient TargetsMacro & Micro Of Food ItemsIntroductionIdeal body weight and other anthropometric details have been covered in a separate section under two lessonsIntroduction To AnthropometryBody Fat MeasurementSo, all the acronyms used here are the same as in the above lessons and we will not be repeating the same here.Macronutrient Targets[table id=46 responsive=scroll responsive_breakpoint="device" /]The - [GLP1 Analogues](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/diabetes-medications/topic/glp1-analogues/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Brands - Generics FDA Warnings Introduction Glucagon-like peptide-1 receptor agonists, also known as GLP-1 receptor agonists or incretin mimetics, are agonists of the GLP-1 receptor. This class of medications is used for the treatment of type 2 diabetes. Mode Of Action They work by copying, - [Angiotensin Converting Enzyme Inhibitors](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/topic/angiotensin-converting-enzyme-inhibitors/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Drug Interactions Brands -- Generics FDA Warnings Introduction Angiotensin-converting-enzyme inhibitors (ACE Inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. Mode Of Action They work by causing relaxation of blood vessels as well as a - [Alpha Blockers](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/topic/alpha-blockers/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Drug Interactions Brands - Generics FDA Warnings Introduction Alpha-blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors. Historically, alpha-blockers were used as a tool for pharmacologic research to develop a greater understanding - [Angiotensin II Receptor Blockers](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/topic/angiotensin-ii-receptor-blockers/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Drug Interactions Brands -- Generics FDA Warnings Introduction Angiotensin II receptor blockers, also known as angiotensin II receptor antagonists, AT₁ receptor antagonists or sartans, are a group of pharmaceuticals that modulate the renin-angiotensin system. Their main uses are in the treatment of hypertension, diabetic - [Beta Blockers](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/topic/beta-blockers/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Drug Interactions Brands -- Generics FDA Warnings Introduction Beta-blockers, also known as beta-adrenergic blocking agents, are medications that reduce your blood pressure. Mode Of Action Beta blockers work by blocking the effects of the hormone epinephrine, also known as adrenaline. Beta-blockers cause your heart - [Centrally Acting Antihypertensives](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/topic/centrally-acting-antihypertensives/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Drug Interactions Brands -- Generics FDA Warnings Introduction Central-acting agents lower your heart rate and reduce your blood pressure. They do this by blocking signals from your brain to your nervous system that speed up your heart and narrow your veins and arteries. Mode - [Diuretics](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/topic/diuretics/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Drug Interactions Brands -- Generics FDA Warnings Introduction Diuretics also called water pills. In the United States, the JNC8 (Eighth Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure) recommends thiazide-type diuretics to be one of the first-line drug - [Vasodilators](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/hypertension-medications/topic/vasodilators/) - Key Points Introduction Mode Of Action Other Benefits Side Effects Contraindications Drug Interactions Brands -- Generics FDA Warnings Introduction Vasodilators are medicines that dilate (widen) blood vessels, allowing blood to flow more easily through. Some act directly on the smooth muscle cells lining the blood vessels. There are many vasodilators but we will discuss only - [Creatine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/creatine/) - Key Points Introduction Benefits Of Creatine Supplementation Side Effects Dosage For Workouts/Exercise Drug Interactions Introduction Creatine is a molecule that's produced in the body from amino acids. It's primarily made in the liver and to a lesser extent in the kidneys and pancreas. It stores high-energy phosphate groups in the form of phosphocreatine which is - [Insulin Resistance & Obesity](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/topic/insulin-resistance-obesity/) - Key Points: Introduction CICO Obesity Model Bad Diet & Insulin Response Endocrine Model Of Obesity The Easy Fix For Obesity Introduction Obesity is an exaggeration of normal adiposity. It is a central player in the pathophysiology of diabetes mellitus, insulin resistance, dyslipidemia, hypertension, and atherosclerosis, largely due to its secretion of excessive adipokines. Excess adipocytes - [Casein](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/casein/) - Key PointsIntroductionBenefits Of CaseinDosage of CaseinSide Effects Of CaseinIntroduction Casein is a family of related phosphoproteins (αS1, αS2, β, κ), commonly found in mammalian milk. It forms about 80% of the bovine milk proteins, forms large colloidal particles with calcium phosphate to form casein micelles, which for many years have been an important subject of - [β-Alanine](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/beta-alanine/) - Key Points Introduction Benefits Of β-Alanine Dosage of β-Alanine Side Effects Of β-Alanine Interaction With Drugs Final Thoughts Introduction β-Alanine (or beta-alanine) is a naturally occurring beta-amino acid and has a chemical formula of C3H7NO2, and a molar mass of 89.093 g/mol. It is a modified version of the amino acid alanine and is a non-essential amino acid. - [BCAA](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/bcaa/) - Key Points Introduction Benefits Of BCAA Side Effects Of BCAA Use Of BCAA By dLife.in Members Interaction With Drugs Final Thoughts Introduction BCAA or Branched Chain Amino Acids includes 3 amino acids- namely Leucine, Isoleucine & Valine. Leucine: Stimulates the release of Growth hormone (HGH) that greatly stimulates muscle growth. Stimulates the release of Insulin - [Pull Ups](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/pull-exercise/topic/pull-ups/) - A pull up is basically pulling your own body weight against gravity. Again you are required to pull yourself up many times while getting up from the floor and this ability is weakened as one age so bodyweight pull-ups are crucial to teach your body to handle its own bodyweight. It is impossible to perform - [Dead Lift](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/pull-exercise/topic/dead-lift/) - Those who know a little bit about lifting might be surprised thinking that the Deadlift is meant for “Advanced lifters” and what is it doing in this list of basic movements, that also listed on the top. Well, the reason why Deadlift is at the top is because it has the most carry-over effect in - [Bent Over Row](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/pull-exercise/topic/bent-over-row/) - The Bent-over row is a compound movement that works your entire back muscles, The Trapezius muscles, Rhomboids, Lats, Forearms, and Biceps. The Bent-over row is one of the staple exercises to include in a Pull workout for overall back hypertrophy and strength development. - [Lat Pull Down](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/pull-exercise/topic/lat-pull-down/) - A lat pull-down is a movement that looks similar to a pull-up but instead of pulling yourself up you pull the bar towards you, its an easier movement compared to a pull-up as you have the option to choose your weights. The Lat pulldown can be used as a hypertrophy oriented exercise as it works - [Biceps Variation 1](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/pull-exercise/topic/biceps-variation-1/) - A bicep curl is the least important but the most performed exercise in the gyms because of the temporary “pump” and gratification it provides. A bicep curl works only on the bicep muscle which is activated maximally while doing the above-mentioned compound exercises. However, it has a place in hypertrophy training as it is an - [Biceps Variation 2](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/pull-exercise/topic/biceps-variation-2/) - A bicep curl is the least important but the most performed exercise in the gyms because of the temporary “pump” and gratification it provides. A bicep curl works only on the bicep muscle which is activated maximally while doing the above-mentioned compound exercises. However, it has a place in hypertrophy training as it is an - [Push Ups](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/push-exercise/topic/push-ups/) - Pushup Front View Pushup Side View - [Squats](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/push-exercise/topic/squats/) - A squat is another exercise after deadlift which is feared by many but we should understand that squatting is the most natural movement that comes to us as Human Beings. Like the deadlift, squatting also has a carryover effect in our day to day life. A squat is simply sitting down as much as you - [Bench Press](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/push-exercise/topic/bench-press/) - Deadlift, squat and bench press are the trinity when it comes to strength building compound exercises. A bench press challenges your upper body pushing strength. The pectoral muscles, the front deltoids, and the tricep muscles are majorly involved in this lift. - [Shoulder Press](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/push-exercise/topic/shoulder-press/) - The ability to lift a heavy object over your head is long considered the showcase of strength and overhead press is just that, you lift a barbell or a dumbbell over your shoulders with the help of your deltoids and triceps. - [Tricep Variation 1](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/push-exercise/topic/tricep-variation-1/) - Strong triceps are very important and can be of huge benefit in increasing the overall strength of the upper body pushing exercises. However, they are maximally trained on your push days along with movements such as bench press and overhead press but still, you can add two variations to isolate and completely fatigue the muscle. - [Tricep Variation 2](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/push-exercise/topic/tricep-variation-2/) - Strong triceps are very important and can be of huge benefit in increasing the overall strength of the upper body pushing exercises. However, they are maximally trained on your push days along with movements such as bench press and overhead press but still, you can add two variations to isolate and completely fatigue the muscle. - [20 Common Mistakes On LCHF / Keto Diet](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-diet/topic/20-common-mistakes-on-lchf-keto-diet/) - Not Eating Enough: Cutting back on carb-rich foods typically means you’re eliminating some staples of your usual diet (bread, pasta, rice, cereal). This equates to eating less than you might normally, and therefore taking in fewer calories. In addition, protein and fat are more satisfying and filling than carbs, so you’ll feel less hungry. Combine - [Devices & Gadgets](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/before-you-begin/topic/devices-gadgets/) - Key Points:Blood Glucose TestingKetone TestingBlood PressureAnthropometryLogging & TrackingAs they say, unless you know it you cannot fix it. Also, in the absence of any measurements, it is impossible to gauge the direction/trend of the movement of various metrics. This is where home testing/recording devices come in handy and you should be able to guide your - [Dysbiosis](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/the-role-of-nutrition-in-human-health/topic/dysbiosis/) - Key Points Introduction What causes dysbiosis and who’s at risk? Dysbiosis in obesity What are the symptoms of dysbiosis? Dietary Solution to Dysbiosis Introduction Your intestinal microbiota is made up of trillions of microorganisms most of which are of bacterial and viral origin that is considered to be non-pathogenic. The microbiota functions in tandem with the - [PCOS - Gynecological Or Metabolic Problem?](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/pcos-polycystic-ovarian-syndrome/topic/pcos-gynecological-or-metabolic-problem/) - Key Points Introduction Hyperinsulinemia Is The Culprit PCOS is a Metabolic Disorder Who can get PCOS Polycystic ovary syndrome (PCOS) is a complex condition that is most often misdiagnosed as a gynecological concern. This is because usually, the symptoms of PCOS starts from irregular menstrual cycle and infertility. These first warning signs of PCOS, make - [PCOS -- Causes & Symptoms](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/pcos-polycystic-ovarian-syndrome/topic/pcos-symptoms/) - Causes Of PCOS Symptoms Of PCOS Self Care At Home Causes Of PCOS Doctors don’t know exactly what causes PCOS. They believe that high levels of male hormones prevent the ovaries from producing hormones and making eggs normally. Genes, insulin resistance, and inflammation have all been linked to excess androgen production. Genes: Studies show that - [PCOS - Medical Approach For Treatment](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/pcos-polycystic-ovarian-syndrome/topic/pcos-pharmaceutical-approach-for-treatment/) - Diagnosing PCOS Medical Treatment Options For PCOS Future Research On Treatment Options PCOS & Pregnancy Diagnosing PCOS If you think you have PCOS, it’s important to seek a diagnosis from your doctor to avoid the long-term health implications. Early diagnosis of PCOS is important as it has been linked to an increased risk for developing - [PCOS & Obesity - The Connection](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/pcos-polycystic-ovarian-syndrome/topic/pcos-obesity-the-connection/) - Introduction Symptoms of PCOS with Obesity The Pathogenetic Connection Between Obesity & PCOS Clinical Features of Obese Women With PCOS The Impact of Body Fat Distribution Most individuals are familiar with the common health risks linked to obesity, including type 2 diabetes, sleep apnea, coronary artery disease (CAD), high blood pressure, and cancer; however, fewer - [Obesity & Diabetes](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/obesity-comorbidities/topic/obesity-diabetes/) - Key Points: Introduction Obesity and type 1 diabetes Obesity and type 2 diabetes How does insulin resistance begin? Body mass index has a strong relationship to diabetes and insulin resistance. In obese individuals, the amount of nonesterified fatty acids, glycerol, hormones, cytokines, pro-inflammatory markers, and other substances that are involved in the development of insulin - [Obesity & Hypertension](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/obesity-comorbidities/topic/obesity-hypertension/) - Key Points: Introduction Hypertension Link Between Obesity & Hypertension Obesity is traditionally defined as a weight ≥20% above the ideal weight, which corresponds to the lowest death rate for individuals of a specific height, gender, and age. More recent guidelines for obesity have introduced the use of a measurement known as body mass index (BMI), - [Obesity & Cardiovascular Disease](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/obesity-comorbidities/topic/obesity-cardiovascular-disease/) - Key Points: Introduction Obesity & Atherosclerosis Obesity and Coronary Artery Disease Obesity and Heart Failure Obesity is among the leading causes of elevated cardiovascular disease (CVD) mortality and morbidity. The prevalence is increasing in both developed and developing countries. According to WHO data, 39% of the global population above 18 years of age are overweight - [Obesity & Autoimmune Disorder](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/obesity-comorbidities/topic/obesity-autoimmune-disorder/) - Key Points Introduction Obesity & Autoimmune Disease Obesity might affect the function of our immune system and play a major role in the development of autoimmune diseases. In the last decades, autoimmune diseases have experienced a dramatic increase in Western countries. The involvement of environmental factors is strongly suspected to explain this rise. Particularly, over - [Inositol](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/topic/inositol/) - Key Points: Introduction Beneficial Effects of Inositol Side Effects and Interactions Inositol, or more precisely myo-inositol, is a carbocyclic sugar that is abundant in the brain and other mammalian tissues; it mediates cell signal transduction in response to a variety of hormones, neurotransmitters, and growth factors and participates in osmoregulation. It is also known by following names: cis-1,2,3,5-trans-4,6-Cyclohexanehexol Cyclohexanehexol Mouse antialopecia factor - [Learning System Content Sharing](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/learning-system-overview/topic/learning-system-content-sharing/) - Key Points Introduction Course Types Links in shared content Introduction The platform has provisions for content sharing across different courses that are offered. This was built into the system as a design so that content duplication is avoided and updating any Lesson or Topic on the platform will update it across all the courses where - [L-Carnitine](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/vitamins-minerals-supplements-for-pcos/topic/l-carnitine/) - Key Points: Introduction Different Types of Carnitine Food Sources Of Carnitine Absorption and metabolism of carnitine Symptoms of Carnitine Deficiency Possible Complications Of Carnitine Deficiency Possible Benefits of Carnitine Dosage Recommendations Interaction With Medications Carnitine, derived from an amino acid, is found in nearly all cells of the body. Its name is derived from the - [N-Acetylcysteine](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/vitamins-minerals-supplements-for-pcos/topic/n-acetylcysteine/) - Key Points: Introduction Anti-Oxidant Activity of NAC Health Benefits of NAC Recommended Dosage of NAC Side Effects Of NAC N-acetylcysteine (NAC) is the supplement form of the amino acid cysteine. Proponents claim that taking N-acetylcysteine supplements can protect against a plethora of health concerns, including respiratory diseases, liver disease, psychiatric disorders, diabetes, certain cancers, and chemical - [Type 1 Diabetes](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/diabetes/topic/type-1-diabetes/) - Key Points Introduction Classification Of Type 1 Diabetes Who Are At Risk? What Are The Symptoms? What Causes Type 1 Diabetes? How To Manage Type 1 Diabetes? How To Lower Chances Of Getting Type 1 diabetes? Introduction Diabetes occurs when your blood glucose, also called blood sugar, is too high. Blood glucose is your main - [Gestational Diabetes](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/diabetes/topic/gestational-diabetes/) - Key Points: Introduction Who Are At Risk? What Are The Symptoms? What Causes Gestational Diabetes? Possible Complications For The Baby How To Manage Gestational Diabetes? How To Lower Chances Of Getting Gestational Diabetes? Introduction Gestational diabetes mellitus (GDM) is diabetes, or high blood sugar levels, that develops during pregnancy. It occurs in about 4% of - [Diabetic Complications](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/diabetes/topic/diabetic-complications/) - Key Points Introduction Microvascular Complications Macrovascular Complications Miscellaneous Complications Introduction A recap of all that we covered so far in the course: Diabetes mellitus is a group of chronic metabolic conditions, all of which are characterized by elevated blood glucose levels resulting from the body's inability to produce insulin or resistance to insulin action or - [Hypertension](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/cardiovascular-disease/topic/hypertension/) - We have covered hypertension in detail in topics within the course as noted below: Insulin Resistance & Hypertension Obesity & Hypertension Hypertension Medications This topic is just included under Cardiovascular Disease for sake of completeness. You are requested to refer to the above Topics in the course as whatever we have to add on - [Atherosclerosis](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/cardiovascular-disease/topic/atherosclerosis/) - Key Points Introduction How does atherosclerosis happen? Why does atherosclerosis happen? How smoking leads to atherosclerosis? Insulin Resistance & Atherosclerosis What are the symptoms of atherosclerosis? What problems does atherosclerosis cause? How does atherosclerosis cause an aortic aneurysm? How is atherosclerosis diagnosed? How is atherosclerosis treated? Introduction Atherosclerosis is the pathological process in the coronary - [Heart Attack](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/cardiovascular-disease/topic/heart-attack/) - Key Points: Introduction Types Of Heart Attack Signs of Heart Attack Risk Factors For Heart Attack Insulin Resistance & CHD Diagnosis Treatment dLife.in Case Studies Introduction People may confuse heart attacks and heart failure. A heart attack occurs when there is a sudden loss of blood supply to the heart, while heart failure is when the heart is unable to pump blood efficiently. Coronary heart - [Cardiomyopathy](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/cardiovascular-disease/topic/cardiomyopathy/) - Key Points: Introduction Types Of Cardiomyopathy Who is at risk for cardiomyopathy? Symptoms of Cardiomyopathy Diagnosis of Cardiomyopathy Treatments for cardiomyopathies Wrapping Up Cardiomyopathy refers to diseases of the heart muscle. These diseases have many causes, signs, and symptoms as well as treatments. In most cases, cardiomyopathy causes the heart muscle to become enlarged, thick - [Cardiac Arrhythmia](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/cardiovascular-disease/topic/cardiac-arrhythmia/) - Key Points: Introduction Types of Arrhythmia Causes of Arrhythmia Diabetes and Arrhythmias Symptoms Of Arrhythmia Diagnostic Tests & Procudires Treatment Medications Surgery Introduction A cardiac arrhythmia is an abnormal heart rate or rhythm. In normal adults, the heart beats regularly at a rate of 60 to 100 times per minute. And the pulse (felt at - [Heart Failure](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/cardiovascular-disease/topic/heart-failure/) - Key Points: Introduction Types Of Heart Failure Ejection Fraction & Its Measurement Conditions That Can Lead To Heart Failure Symptoms Of Heart Failure Targeting insulin resistance in heart failure Introduction The term "heart failure" can be frightening. It doesn't mean the heart has "failed" or stopped working. It means the heart doesn't pump as well - [Diabetes Diagnosis & Management](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/lessons/diabetes/topic/diabetes-diagnosis-management/) - Key Points Introduction Standard Diagnosis Our Suggestion For Diagnostic Tests Standard Care Diabetes Management dLife.in's Approach To Diabetes Management Introduction Diabetes types are currently classified into three distinct groups. The general symptoms of diabetes, which can be confirmed by lab tests, are: excessive thirst and hunger frequent urination drowsiness or fatigue dry, itchy skin blurry vision slow-healing wounds numbness - [NAFLD - The Progression Details](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/non-alcoholic-fatty-liver-disease-nafld/topic/nafld/) - Key Points: Introduction The Statistics NAFL NASH Cirrhosis Hepatocellular carcinoma (HCC) Fatt Liver Disease & Prevention (Video) Introduction Non-alcoholic fatty liver disease (NAFLD) is a very common disorder and refers to a group of conditions where there is an accumulation of excess fat in the liver of people who drink little or no alcohol. NAFLD - [Liver Disease - Causes Symptoms Diagnosis & Prevention](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/non-alcoholic-fatty-liver-disease-nafld/topic/liver-disease-causes-symptoms-and-diagnosis/) - Key Points Introduction Risk Factor For Liver Disease What Causes Liver Disease Symptoms Of Liver Disease Diagnosis Of Liver Disease Prevention Of Liver Disease Introduction Your liver is an important organ that performs hundreds of tasks related to metabolism, energy storage, and detoxification of waste. It helps you digest food, convert it to energy, and - [Current Treatment Options For NAFL and NASH](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/non-alcoholic-fatty-liver-disease-nafld/topic/current-treatment-options-for-nafl-and-nash/) - Introduction Diet & Lifestyle Modification Supplementation Medicines Introduction NAFLD is considered to be the hepatic manifestation of metabolic syndrome (MS). Approximately 50% of patients with type 2 diabetes mellitus (DM2) have NAFLD and, regardless of body mass index, have the more severe liver disease than non-diabetic patients [2,3]. NASH is associated with both increased cardiovascular ## Quizzes - [Course Rating Review & Feedback](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/quizzes/course-rating-review-feedback/) - There are three questions to be answered in this assignment. Feedback will be used for internal records and ratings, and reviews may be published in your name. - [Quiz No 4](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/quizzes/quiz-no-4/) - 55 questions in this quiz. 5 questions with 2 marks and rest are 1 marks each. The questions with 2 marks will have the same mentioned. 60 minutes allowed to complete the quiz. All questions must be answered. No negative marking. This quiz cannot be retaken to improve the score. - [Quiz No 3](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/quizzes/quiz-no-3/) - 60 questions in this quiz. 60 minutes allowed to complete the quiz. All questions must be answered. No negative marking This quiz cannot be retaken to improve the score. - [Cholesterol Revision Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/lipid-peroxidation/quizzes/cholesterol-revision-quiz/) - 9 questions in this quiz. 10 minutes are allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake quiz once - [Metabolic Disorders Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/non-alcoholic-fatty-liver-disease-nafld/quizzes/metabolic-disorders-quiz/) - 60 questions in this quiz. 75 minutes are allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake the quiz once - [Hormones Revision Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/thyroid/quizzes/hormones-revision-quiz/) - 59 questions in this quiz. 75 minutes are allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake quiz once - [Insulin Revision Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/insulin/quizzes/insulin-revision-quiz/) - 30 questions in this quiz. 45 minutes are allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake quiz once - [Emerging Science Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/understanding-autoimmune-conditions-and-the-role-of-carnivore-diet-in-management/quizzes/emerging-science-quiz/) - 15 questions in this quiz. 20 minutes are allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake the quiz once - [Vitamins Revision Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/vitamins/quizzes/vitamins-revision-quiz/) - 37 questions in this quiz. 45 minutes allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake quiz once - [Sports Nutrition Revision Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/high-intensity-interval-training-hiit/quizzes/sports-nutrition/) - 27 questions in this quiz. 35 minutes allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake quiz once - [Supplements Revision Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/supplements/quizzes/supplements-revision-quiz/) - 30 questions in this quiz. 40 minutes allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake quiz once - [Minerals Revision Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/minerals/quizzes/minerals-revision-quiz/) - 39 questions in this quiz. 40 minutes allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake quiz once - [Nutrition Revision Quiz](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/lessons/low-carb-diet/quizzes/nutrition-revision-quiz/) - 60 questions in this quiz. 75 minutes are allowed to complete the quiz. All questions must be answered. No negative marking. Question types are: single-choice, multiple-choice, and fill-in-the-blanks as correct answers. Allowed to retake quiz once - [Documents Upload](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/lessons/learning-system-overview/quizzes/documents-upload/) - The questions in this quiz require document uploads and providing details of your community account which are necessary before you can move to the next step. The grading is automated so once you complete you can move to the next step in the course. The questions under this cannot be retaken. So, please sure that - [Quiz No 1](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/quizzes/quiz-no-1/) - 60 questions in this quiz. 60 minutes allowed to complete the quiz. All questions must be answered. No negative marking This quiz can be retaken once to improve the score. This will be applicable to quiz no 1 and quiz no 2. Question types are: single choice, multiple-choice and fill in the blanks as correct - [Quiz No 2](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/quizzes/quiz-no-2/) - 60 questions in this quiz. 60 minutes allowed to complete the quiz. All questions must be answered. No negative marking This quiz can be retaken once to improve the score. This will be applicable to quiz no 1 and quiz no 2. Two new question types are added in this quiz. So Single Choice, Multiple - [Internship Data Uploads](https://www.elearning.dlife.in/courses/low-carb-nutrition-diploma/quizzes/internship-data-uploads/) - The Diploma course has two assignments related to the internship on the forum as part of the course. Total marks for this are 50 (10 for interaction on forum and 40 for posting recipes using the Recipe Posting module) and will be graded by one of the course instructors. - [OBESITY & PCOS - Quiz 1](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/quizzes/obesity-pciq-quiz-1/) - [OBESITY & PCOS - Quiz 2](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/quizzes/obesity-pcos-quiz-2/) - [Certificate Course Internship Data Upload](https://www.elearning.dlife.in/courses/low-carb-nutrition-for-obesity-pcos-certificate-course/quizzes/certificate-course-internship-data-upload/) - For certificate courses, there's no interaction on the forum involved. So, this will only have one part which is related to the Recipe Posting only and carries 40 marks. - [CardioDiabesity - Quiz 1](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/quizzes/cardiodiabesity-quiz-1/) - [CardioDiabesity - Quiz 2](https://www.elearning.dlife.in/courses/low-carb-nutrition-certificate-diabetese-obesity/quizzes/cardiodiabesity-quiz-2/) ## Course Notes - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-34/) - Enteric Nervous System has 100 million neurons via vagus nerve bidirectional signalling.Serotonin, Ghrelin, and Cholecystokinin influence appetite, satiety and stress response. Serotonin affects moodSCFA's can cross bbb affecting neuroinflammatino, nt production can affect behaviour and mood.Gut is pivotal site for immune activity.Autonomous nervous system - SNS and PNSSNS-fight or flight, activates due to stress or - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-27/) - For digestion of carbs. Saliva and pancreas. Salivary Amylase Ptyalin - starch digestion from foods, Pancreatic Amylase secreted into small intestine where bulk of carb digestion in alkaline environment.Alpha amylase- Ptyalin and pancreas, hydrolysis of starch into maltose and other sugars. pH 6.7 to 7. Digestion begins in mouth and ends in small intestine.Beta amylase-Plants, - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-30/) - Lipase turns triglycerides into free fatty acids and glycerol, produced in pancreas, but it is also secreted by mouth, stomach and intestines.It is used in energy metabolism and production of biofuels.Pancreatic lipase goes into small intestine for dietary fats.Lingual and Gastric Lipase for mouth and stomach. Infants - milk fat digestionHepatic Lipa - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-96/) - Digestive tract is 10 meters long. MESSLAMouth, Esophagus, Stomach, Small Intestine, Large Intestine, AnusLPG - Solid organsSmall Intestine - DJILarge Intestine - Appendix, Cecum, Colon and Rectum - ACeCoRCecum is first part of large intestine, then colon and rectumGut flora - Bacteria for healthy digestion.Digestion converts food to sugar, amino acids, or fatty acids.Proteins turn - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-63/) - Humans and chimps seperate about 7.5 million years ago.Sumerians-first civilization.Homo sapiens 200,000 years ago.Human language and symbols 50000 years ago - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-67/) - Before 3 million years humans consumed meat. Stone age weapons date 2.6 million years. Homo erectus were primarily meat eaters. Crops came roughly 10,000 years ago. Rice came 10-14000 years ago. Origin was from china 8,200-13,500 years ago. Wheat cultivated in Iran 9,600 BC. Grown in south eastern Turkey karacadeg mountain. In India wheat came - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-64/) - Bipedalism evolved over 4 million years ago. Cultural diversity, symbolic expression - 100,000 years ago. Homo sapiens, chimpanzees and gorillas have a common ancestor lived between 6 and 8 million years ago. Human Fossils 2 and 6 million years ago wholly from Africa. Modern humans came to Australia within the past 60000 years and Americas - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-65/) - Notes: - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-95/) - motion: chew, squeeze, mixdigestive juices, bile, enzymesamylase:ptyalin.protease, pepsin, trypsin, lipase, deoxyribonuclease, ribonuclease. - [](https://www.elearning.dlife.in/lds-course-notes/notes-taking-explained-29/) - Notes: this is test note! - [Incretin — GLP-1 And GIP](https://www.elearning.dlife.in/lds-course-notes/incretin-glp-1-and-gip-28/) - Notes:GLP1 - Glucagon like peptide 1GIP - Gastric Inhibitor PolypeptideBoth - [Obesity Is A Metabolic Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-is-a-metabolic-disorder-19/) - Notes: - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-63/) - Notes:2.6 million yrs ago, meat eating - [Quizzes and Assignments](https://www.elearning.dlife.in/lds-course-notes/quizzes-and-assignments-11/) - Notes: for Quiz one re-attempt will be allowed. This reattempt is in case I feel that if I have scored low and I want to take one more reattempt, then I will be allowed one more attempt. For assignments once it has been uploaded, after that nothing will be allowed. No second chance will be given. The - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-36/) - Notes:protein digestion starts in stomach.When protein rich food enter the stomach it is mixed with enzyme pepsin and HCL (pH is 1.5-3.5).when chyme enters the small intestines NaHCO3is released to nuetralize the acid effectenzymes like trypsin,chymotrypsin and elastase aid in protein digestionPROTEOLYSISAn enzyme found in the wall of small intestine caleed enterokinase binds to trysinogen - [Carbohydrates](https://www.elearning.dlife.in/lds-course-notes/carbohydrates-36/) - Notes:glucose is also called blood sugar or dextrose.monosaccharides are glucose ,fructose,glactosefructose is also called as levulose it is found in fruit, - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-35/) - Notes:Krebs Cycle? - [Test And Numbers & CAC Score](https://www.elearning.dlife.in/lds-course-notes/test-and-numbers-cac-score-17/) - CHOLESTEROL - Test and Numbers & CAC Score - [Foods: The ‘Yes’, ‘May’ & ‘Never’ List](https://www.elearning.dlife.in/lds-course-notes/foods-the-yes-may-never-list-26/) - Notes:What is Glycemic Index? - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-94/) - Small Intestine has 3 parts:duodenum, jejunum, ileumLarge intestine: appendix, cecum, colon, rectumAppendix is finger-shaped pouch attached to cecum. Cecum is first part of large intestine.Amino acids make up protein. Proteins break into amino acidsFatty acids make up fats. Fats break into fatty acids and glycerolCarbs break into simple sugars (glucose)Broken down food is absorbed into bloodstream - [Sugar & Carb Addiction](https://www.elearning.dlife.in/lds-course-notes/sugar-carb-addiction-29/) - Notes:1. Why is sugar addictive?2. - [Myth: Dietary Fat Causes Weight Gain](https://www.elearning.dlife.in/lds-course-notes/myth-dietary-fat-causes-weight-gain-24/) - Notes:1. Isocaloric - eating exact same amount of calories every day2. Mastication - Chewing3. Incretin - metabolic hormoines released by gut after eating to lower blood sugar levels.4. Homeostatis - A self regulating process by which a biological system maintains internal stability while adjusting to changing external conditions5. Leptin - hormone released by body's fat - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-33/) - Notes:Vagus Nerve is the primary nerve connection .Serotonin is predominately produced in gut .Hormones like cholecystokinin,ghrelin,serotonin hormones play a role in appetite,stress.Microbiota the gut microbes results in neuroinflammation,SNS (fight and flight system)activates in response to stessor dangerIt increases heart rate ,redirects blood to muscles ,dilates pupilParasympathetic Nervous Systemrest and digest system,conserves body energy,slows heart rate,increases - [20 Common Mistakes On LCHF / Keto Diet](https://www.elearning.dlife.in/lds-course-notes/20-common-mistakes-on-lchf-keto-diet-17/) - 20 Common Mistakes On LCHF / Keto DietNot eating enough: Cutting back on carb-rich-foods equates to eating less than you might normally eat. Do not go below 1200 calories as this will lead to starvation mode and also muscle loss slowing down your metabolism.Trying to go low carb and low fat: Fear of eating fat - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-62/) - Notes:proto hominin bipedalaustralopithecuspalanthropushomo labilis homo erectus homo ergaster firehomo sapiens 2lakh years ago - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-26/) - Notes:Amylase digests carbohydrates into sugars .Mainly it is : salivary amylase and pancreatic amylaseAmylase works in ph 6.7-7Three types of Amylase:Alpha Amylase:produced by salivary glands and pancreasBeta Amylase :found in plants ,bacteria and fungiGamma Amylase:in plants andbacteria - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-29/) - Notes:Pancreatic Lipase is in small intestines and digest dietary fatsLingual and gastric lipases --important in infants for milk fat digestionHepatic Lipase --Inliver cells for cholestrol levelsMicrobial Lipases--produced by microorganism used in industrial applicationBIOLOGICAL ROLESDigestion:coverts dietary triglycerides into absorbable componentMetabolism:Pathophysiology:Alterations in lipase activity is associatedwith obesity,pancreat - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-93/) - Notes:1. Solid organs of digestive system - liver, pancreas and gall bladder.2. Small intestine has 3 parts - duodenum, jejunum and ileum.3. large Intestine has - - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-66/) - Notes:1. Rice domesticated in China.2. Wheat domesticated in Babylon.3. Athero3. Atheroscerosis - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-62/) - Notes:1. 2.6 mn years ago, humans started consuming meat. Earliest diet similar to Chimps i.e. fruits, leaves, bark, insects.2. The carnivory of Himinins is unique in 3 ways Use of flaked stone tools to access animal resourcesAcqn of resources from animals much larger than the Hominins themselves.Procurement of Animal resources by scavenging.Cimpanzees eat only small portions - [The Current Situation](https://www.elearning.dlife.in/lds-course-notes/the-current-situation-26/) - Notes:Vegans and KetoKeto diet is mainly low carb high fat diet--it will help us keep low insulin level and even fat burning. helps to fight in diseases like obesity,diabetesetcKeto diet is coming in the world as the most popular way to correct all the diseases - [The Atkins Diet](https://www.elearning.dlife.in/lds-course-notes/the-atkins-diet-20/) - THE ATKINS DIETThis diet though not looking at macros, emphasises the word low carb, and primarily was a weight loss diet. This diet shifted the focus away from calorie counting for weight loss and proposed eating as much as protein and fat as you wanted, as long as foods in high carbs were completely avoided.There - [The Rise of Modern Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-rise-of-modern-chronic-diseases-25/) - Notes:Chronic diseases are more costly and prevalent in the US Nearly half of the Americans are suffering from atleast one chron - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-92/) - Notes:small intestines is around 2700square feet size of a tennis courtglands in mouth:parotid,submandibular,sublingualamylase lipase is the enzyme in mouth that will digest starch and lipidsesophagus is 25 cm longlayers of stomach:mucosa,submucosa,musclelayer,serosastomach has HCl,NaCl,Pepsinogenmucous secreted by gastric glands releases HCO3- that prevents lininglower end of the stomach has pylorus which has a pyloric sphincter which helps - [The Rise of Modern Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-rise-of-modern-chronic-diseases-26/) - Notes: - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-65/) - Notes:Mainly Humans consumed meat 3million years ago.Homo erectus before Homosapiens mainly depended on meat ,fruits and vegetables.wheat was first grown in Karaceadeg Mountain in Southeastern Turkeyemmer wheat came to India 6500 years ago - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-61/) - Notes:human evolution originated from apelike ancestors over a period of 6million years ago.bipedilism ability to walk on two legs 4million years agolarge and complex brain --ablity to make tools,develop language came around 100000 years agoHumans are primates.Homo sapiens and great apes and chimpanzees have same ancestors.Mainly originated from AfricaHumans migrated from Africa to Asia around - [Thyroid Stimulating Hormone – TSH](https://www.elearning.dlife.in/lds-course-notes/thyroid-stimulating-hormone-tsh-22/) - THYROID STIMULATING HORMONE (TSH)Thyroid- stimulating hormone is produced by the pituitary gland that stimulates the thyroid gland to produce T4 and T3 which stimulates the metabolism of almost every tissue in the body by the thyroid gland.T4 and T3 are essential to maintain the body's metabolic rate, heart, and digestive functions, muscle control brain development - [Somatostatin](https://www.elearning.dlife.in/lds-course-notes/somatostatin-25/) - SOMATOSTATINSomatostatin was first discovered in hypothalamic extracts and identified as a hormone that inhibited the secretion of growth hormones. It is a naturally occurring peptide hormone that regulates the endocrine system - [Secretin](https://www.elearning.dlife.in/lds-course-notes/secretin-15/) - SECRETINSecretin is a peptide hormone composed of 27 amino acids. It stimulates the pancreas to release bicarbonate-rich fluid, neutralising stomach acid entering the duodenum. It regulates secretions from the stomach, pancreas and stomach. Secretin regulates water homeostasis throughout the body and influences the alkaline environment of the duodenum. It neutralising the acid nature which is coming - [Progesterone](https://www.elearning.dlife.in/lds-course-notes/progesterone-22/) - PROGESTERONEProgesterone is an endogenous steroid that belongs to the group of steroid hormone. It is produced by the female body after ovulation during the second half of menstrual cycle.Synthetic steroid hormones with progesterone like properties are called progestin. Progestin is often combined with estrogen, another hormone to develop contraceptives such as birth control pills and - [Peptide YY](https://www.elearning.dlife.in/lds-course-notes/peptide-yy-22/) - PEPTIDE YYFirst isolated in 1983, Peptide YY is a gastrointestinal hormone consisting of 36 amino acids with tyrosine residues. PYY is structurally related to two other gut peptide hormones, pancreatic polypeptide and neuropeptide Y. Together they are called the pancreatic polypeptide-peptide YY-neuropeptide Y (PP-PYY-NPY).Your body produces PYY when there is food in the digestive tract, - [Oestrogen Or Estrogen](https://www.elearning.dlife.in/lds-course-notes/oestrogen-or-estrogen-21/) - OESTROGEN OR ESTROGENEstrogen is one of two main sex hormones that women - [Norepinephrine](https://www.elearning.dlife.in/lds-course-notes/norepinephrine-22/) - NOREPINEPHRINENorepinephrine also called noradrenaline is anaturally occurring chemical in the body that acts as both a stress hormone and ne - [Melatonin](https://www.elearning.dlife.in/lds-course-notes/melatonin-25/) - MELATONIN - [Luteinizing Hormone](https://www.elearning.dlife.in/lds-course-notes/luteinizing-hormone-16/) - LUTEINISING HORMONELH plays a crucial role in the reproductive systems of both men and women.Produced by the pituitary gland LH levels are regulated by the hypothalamic-Pituitary-Gonadal (HPG) axis, which oversees reproductive functions.In women LH triggers ovulation within the ovaries, while in men, it supports testosterone product in the testes.LH is a key reproductive hormone secreted - [Leptin](https://www.elearning.dlife.in/lds-course-notes/leptin-28/) - LEPTIN - [Insulin Resistance & Endothelial Dysfunction](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-endothelial-dysfunction-27/) - Insulin Resistance & Endothelial DysfunctionThe endothelium is a thin membrane that lines the inside of the heart and blood vessels. Endothelial cells release substances that control vascular relaxation and contraction as well as enzymes that control blood clotting, immune function, and platelet (a colourless substance in the blood) adhesion.Nitric Oxide (NO) is considered to be - [Insulin Resistance & Dyslipidemia](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-dyslipidemia-24/) - Insulin Resistance & DyslipidemiaDyslipidemia occurs when someone has abnormal levels of lipids in their blood.The most common forms of dylipidemia involve:high level of low-density lipoprotein (LDL)low levels of high-density lipoproteins (HDL)high levels of triglycerideshigh cholesterol, which refers to high LDL and triglyceride levels - [Insulin Resistance & Osteoarthritis](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-osteoarthritis-22/) - Insulin Resistance & OsteoarthristisThe metabolic syndrome which has insulin resistance as its central feature, includes 3 or more of the following factors:hypertensionincreased triglyceridesreduced HDL-cholesterolincreased waist circumferenceelevated fasting glucoseIncreasing numbers of metabolic syndrome components predict an increased occurrence and progression of radiographic knee OA.Osteoarthritis is seen frequently not only in full-blown diabetics but also in "Insulin - [Insulin Resistance & Uric Acid](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-uric-acid-24/) - Insulin Resistance & Uric AcidUric acid is a natural waste product from the digestion of foods that contain purines. Purines are normally produced in the body and are also found in some foods and drinks. Foods with a high content of purines include liver, anchovies, mackerel, dried beans and peas, and beer.Most uric acid dissolves - [Insulin Resistance & Cardiovascular Disease](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-cardiovascular-disease-26/) - Insulin resistance & Cardiovascular DiseaseInsulin resistance can induce an imbalance in glucose metabolism that generates chronic hyperglycemia. This, in turn, triggers oxidative stress and causes an inflammatory response that leads to cell damageThomas Dayspring says majority of heart attacks are due to Insulin Resistance. LDL is a near worthless predictor for cardiovascular issues.Too much fructose - [Insulin Resistance & Cancer](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-cancer-25/) - Insulin Resistance & CancerObesity has been associated with an increased risk of esophageal cancer, pancreatic cancer, thyroid cancer, liver cancer, and gall bladder cancer. And hyperinsulinemia/insulin resistance is associated with obesity.One of the theories behind obesity catalyzing cancer is that adipose tissue also creates an inflammatory environment that enhances the ability of tumor cells to - [Insulin Resistance & Hypothyroidism](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-hypothyroidism-21/) - Insulin Resista - [Insulin Resistance & NAFLD](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-nafld-26/) - Insulin Resistance & NAFLDNon-alcoholic fatty liver disease (NAFLD) is when there is an accumulation of excess fat in the liver of people who drink little or no alcohol. The build of fat is not caused by heavy alcohol use.A small group of people with NAFLD may have a more serious condition named non-alcoholic steatohepatitis (NASH) - [Insulin Resistance & PCOS](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-pcos-24/) - Insulin Resistance & PCOSPCOS usually pronounced "pee-kos" stands for PolyCystic Ovarian Syndrome. It is the most common endocrine condition in women during their reproductive years and it affects up to quarter of all women.PCOS diagnosis is based on a combination of:Hyperandrogenism, where excess levels of male hormones the main one being testosterone is circulating in - [Insulin Resistance & Obesity](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-obesity-31/) - Insulin Resistance & ObesityObesity pathogenesis involves two related but distinct processes:sustained positive energy balance (energy intake greater than energy expenditure) andresetting of the body weight 'set point' at an increased value.There is absolutely no science behind the 60% energy from carbs diet that is widely propagated. In fact the requirement of carbohydrates by the body - [Insulin Test – Setting The Bar Right](https://www.elearning.dlife.in/lds-course-notes/insulin-test-setting-the-bar-right-22/) - Insulin Test - Setting The Bar RightAn insulin blood test also referred to as the fasting insulin test is used to measure the amount of insulin in the body. It is used to monitor the treatment of abnormal insulin levels and also to monitor insulin resistance.A fasting insulin level lab range defined as normal is - [Insulin](https://www.elearning.dlife.in/lds-course-notes/insulin-25/) - 13. InsulinInsulin is composed of two chains, an A chain (with 21 amino acids) and B chain (with 30 amino acids), which are linked by sulfur atoms.Hormones are chemical messengers that instruct certain cells or tissues to act in a certain way that supports a particular function in the body.Insulin is a natural hormone produced - [Incretin — GLP-1 And GIP](https://www.elearning.dlife.in/lds-course-notes/incretin-glp-1-and-gip-27/) - 12. Incretin - GLP-1 AND GIPOver 100 years have passed since the discovery of the incretin concept, which later opened up the possibility of a novel therapy in the treatment of diabetes.The gastric inhibitor polypeptide (GIP) and glucagon-like-peptide-1 (GLP-1) are the two primary incretin hormones secreted from the intestine on ingestion of glucose or nutrients - [Human Growth Hormone](https://www.elearning.dlife.in/lds-course-notes/human-growth-hormone-14/) - 11. Human Growth HormoneHuman growth hormone, or HGH also called somatotropin, is produced by the pituitary gland and stimulates growth in children. After the growth plates in bones close, HGH does not contribute to height increase, yet it remains vital. Post-growth, HGH plays crucial role in maintaining body structure and metabolic functions, such as regulating - [Ghrelin](https://www.elearning.dlife.in/lds-course-notes/ghrelin-26/) - 10. GhrelinGhrelin was discovered in 1999. Ghrelin levels are primarily regulated by food intake. Levels of ghrelin in the blood rise just before eating and when fasting. Hence, ghrelin is thought to play a role in mealtime 'hunger pangs' and the need to begin meals. Ghrelin is central to appetite and the release of growth hormone. It - [Glucagon](https://www.elearning.dlife.in/lds-course-notes/glucagon-33/) - 9. Glucagon - [Gastrin](https://www.elearning.dlife.in/lds-course-notes/gastrin-18/) - 8. GastrinGastrin is a specific hormone primarily secreted by G cells in the gastric antrum, duodenum and pancreas. It plays a crucial role in the digestive process by regulating gastric acid secretion, promoting mucosal growth in the stomach, enhancing gastric mobility, coordinating digestive processes and maintaining homeostasis through feedback mechanisms. Its roles are critical for - [Follicle-stimulating Hormone](https://www.elearning.dlife.in/lds-course-notes/follicle-stimulating-hormone-29/) - 7. Follicle-stimulating hormone (FSH)FSH is one of the hormones essential to pubertal development and the function of women's ovaries and men's testes.In a woman, high TSH levels may indicate:loss of ovarian function or failuremenopausepolycystic ovarian syndrome, a condition in which a woman's hormones are out of balance, causing ovarian cystsa chromosomal abnormality such as Turner's - [Cortisol](https://www.elearning.dlife.in/lds-course-notes/cortisol-26/) - 6. CortisolCortisol is a steroid hormone produced by the adrenal gland that regulates a wide range of processes throughout the body, including metabolism and the immune response. It also has a very vitl role in helping the body respond to stress.Whenever a body experiences something it perceives as a threat, a chemical known as adrenocorticotropic - [Cholecystokinin](https://www.elearning.dlife.in/lds-course-notes/cholecystokinin-17/) - 5. Cholecystokinin (CCk)CCk is a multifaceted hormone that regulates digestive health and appetite. It influences satiety and potentially impacting mood and anxiety.There are 2 main receptors for CCK:CCK1 receptor (CCK-A): primarily found in gastrointestinal tract for digestive functions.CCK2 recepto - [Amylin](https://www.elearning.dlife.in/lds-course-notes/amylin-28/) - 4. AmylinAmylin is a 37-amino acid peptide glucoregulatory hormone that is co-secreted with insulin from the pancreatic beta cells. Insulin triggers glucose uptake in muscles and liver cells, effectively removing glucose from the bloodstream and making it available for energy use and storage. Amylin regulates glucose homeostasis by inhibiting gastric emptying, inhibiting the release of the - [Aldosterone](https://www.elearning.dlife.in/lds-course-notes/aldosterone-21/) - 3. AldosteroneAldosterone is a crucial hormone produced by the adrenal cortex, primarily in the zona glomerulosa.It plays a fundamental role in regulating sodium and potassium levels, fluid balance and blood pressure. It is essential component for sodium conservation in our kidneys (maintain the balance of salt and water) different salivary glands, sweat glands, and colon. - [Adiponectin](https://www.elearning.dlife.in/lds-course-notes/adiponectin-32/) - 2. Adiponectin Adiponectin is a protein hormone and adipokine which is involved in regulating glucose levels as well as fatty acid breakdown. It is encoded by the ADIPOQ gene and it is produced primarily in adipose tissue, but also in muscle and even in the brain.Low adiponectin might not be a great reflection on your health - [Adrenaline](https://www.elearning.dlife.in/lds-course-notes/adrenaline-31/) - HORMONES AND METABOLIC SYNDROME1. Adrenaline Adrenaline, a hormone (and also a drug) is produced in the medulla in the adrenal glands as well as some of the central nervous system's neurons. It is also known as epinephrine. Adrenaline and noradrenaline are two separate but related hormones and neurotransmitters.Within a couple of minutes, during a stressful situation - [Fats](https://www.elearning.dlife.in/lds-course-notes/fats-28/) - FATSThere are four types of fats: saturated, monounsaturated, polyunsaturated and trans. Despite dividing fatty acids into these four groups, no naturally occurring fat is composed of 100% of a single fatty acid group.Saturated Fat (SFA): Under the dietary guidelines to restrict saturated fats, chronic illness has risen rather declined.Monounsaturated Fat (MUFA): Mono means one, signifies - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-34/) - PROTEINSProtein provides 4 calories of energy per gram.Functions Based Types of ProteinsThere are a total of 7 different protein types under which all protein fall namely:Antibodies that defend the body against antigens and foreign invaders,Contractile protein (actin & myosin) responsible for muscle contraction and movement.Enzymes (like lactase & pepsin) are proteins that facilitate and speed - [Carbohydrates](https://www.elearning.dlife.in/lds-course-notes/carbohydrates-35/) - CARBOHYDRATESCarbs are molecules that have carbon, hydrogen and oxygen atoms (CHO).Dietary carbohydrates can be split into 3 main categories - Sugars, Starches, and Fiber.Sugars are short chain carbohydrates found in foods. Examples are glucose, fructose, galactose and sucrose. Simple sugars are made up of 2 classes of sugars baed on their chemical structure.Sugars having 1 - [Body Fat Measurement](https://www.elearning.dlife.in/lds-course-notes/body-fat-measurement-17/) - BODY FAT MEASUREMENTMeasuring fat is necessary to achieve a healthy body composition. Bad body composition means more fat & less muscle. There are various ways the measurements can be done.1. Densitometry In this the human body is divided into 2 compartments. Fat FM and Fat-Free FFM.The gold standard is densitometry is under water weighing. The process requires - [Introduction To Anthropometry](https://www.elearning.dlife.in/lds-course-notes/introduction-to-anthropometry-26/) - ANTHROPOMETRYAnthropometry or anthropometrics is the study of human body measurements. At its most basic form anthropometrics is used to help scientists and anthropologists understand physical variations and proportions among humans. Anthropometry is useful for a wide array of applications. The measures analysed are usually weight, height, body mass index (BMI), body circumference (arm, hip, and calf), - [Diabetes Medications](https://www.elearning.dlife.in/lds-course-notes/diabetes-medications-5/) - Notes: - [Sugar & Carb Addiction](https://www.elearning.dlife.in/lds-course-notes/sugar-carb-addiction-28/) - SUGAR & CARB ADDICTION - [Aldosterone](https://www.elearning.dlife.in/lds-course-notes/aldosterone-20/) - Notes:Aldosteron's function is to regulate sodium homeostasis to control blood volume and pressure this hormone for sodium conservation in kidney ,different salivery glands, sweat glands and colon indirectly it helps to maintain the pH balance of our food with electrolite levels. - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-33/) - Notes:Proteins digestion stomach --enzymes pepsin and hydrocloride acid (HCL;0.5%)Pepsin cuts proteins into smaller polypeptides and there constituent amini acids .this food and gastric mixure called chyme enters the small intestine ...pancreas releases sodium bicarbonate to neutralise HCL..this helps in the protect the linning of the instestine .small intestine :digestive juices ..protein breaking further.Secratin also stimulates the - [The Role Of Nutrition In Human Health](https://www.elearning.dlife.in/lds-course-notes/the-role-of-nutrition-in-human-health-24/) - THE ROLE OF NUTRITION IN HUMAN HEALTHIt has been proven the deficiency of vitamin B12 can cause mental illness. Psychiatric manifestations of vitaminB12 difiency can include:Depression, Apathy, Irritability, Dementia, Catatonia, Delirium and Hallucinations.Vitamin D deficiency can lead to loss of bone density. - [Myth: Dietary Fat Causes Weight Gain](https://www.elearning.dlife.in/lds-course-notes/myth-dietary-fat-causes-weight-gain-23/) - MYTH: DIETARY FAT CAUSES WEIGHT GAIN - [Myth: Saturated Fat Causes Heart Disease](https://www.elearning.dlife.in/lds-course-notes/myth-saturated-fat-causes-heart-disease-34/) - Atherosclerosis' increased circulating LDL particles (not take - [Myth: Plant Based Diets Are The Best](https://www.elearning.dlife.in/lds-course-notes/myth-plant-based-diets-are-the-best-35/) - Plant Based Has A Lot Of Toxin/Anti Nutrient Load1. Seeds - Anti nutrient2. Grains - Lectins3. Nuts - Phytic Acid4. Beans - Enzyme Inhibitors + Endocrine Disruptors + Saponins5. Roots - Glycoalkaloids (example Potato)6. Stems - Glucosinolates (example Broccoli)7. Leaves - Oxalates8. Fruits - Phenolics, Cyanogenic Glycosides, SalicylatesIf you have no cholesterol in your body - [American Diabetes Assn – Low Carb & Very Low Carb Diet For Diabetes](https://www.elearning.dlife.in/lds-course-notes/american-diabetes-assn-low-carb-very-low-carb-diet-for-diabetes-19/) - Notes: - [Myth: Carbohydrates Are Essential](https://www.elearning.dlife.in/lds-course-notes/myth-carbohydrates-are-essential-44/) - Notes: - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-32/) - GUT BRAIN AXISA) Autonomic Nervous System (ANS) is a division of peripheral nervous system that controls involuntary body functions and is divided into 2 main branches:1. Sympathetic Nervous System (SNS) often referred to as 'flight or flight' system which activates in response to stress or danger, preparing the body for physical activity. It increases heart - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-25/) - AMYLASEAmylase plays a pivotal role in digestion of carbohydrates breaking down the complex polysaccharides into simpler absorbable forms. Found mainly in the saliva and pancreas, amylase is the first enzyme to interact with food. This process is vital for effective digestion and nutrient absorption.Optimal pH for amylase activity is between 6.7 and 7.0At extreme pH - [Dietary Guidelines Myths & Facts](https://www.elearning.dlife.in/lds-course-notes/dietary-guidelines-myths-facts-29/) - CARDIODIABESITY IS AN EPIDEMICCardiodiabesity is an umbrella term encompassing - cardiovascular disease, Diabetes & Obesity the three hallmark of disorders influenced by Insulin Resistance.Low carb diet have shown to reverse insulin resistance. - [Protease](https://www.elearning.dlife.in/lds-course-notes/protease-19/) - PROTEASE (PR)Proteolytic enzymes (protease) are enzymes that break down protein.Protease (PR, proteinase or peptidase are group of proleolytic enzymes whose major function is to catalyze the hydrolysis of pepetide bonds that link amino acids together in a polypeptide chain with high sequence selectivity and catalytic proficiency.Protease plays critical roles in many biological processes such as - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-28/) - Lipase is a crucial enzyme that catalyzes the hydrolysis of triglycerides into free fatty acids and glycerol playing a vital role in lipid metabolism and digestion of various organisms. This enzyme is predominantly produced in the pancreas but is also secreted by the mouth, stomach and intestine making it essential for the digestion and absorption - [Cortisol](https://www.elearning.dlife.in/lds-course-notes/cortisol-25/) - Notes:when ever body perceives threat it releases adrenocorticotropic hormone(ACTH) is released in brain, this makes adrenal glands release cortisol. high cortisol levels include frequent urination and thirst supplements like fish oil and ashwaganda helps in reducing cortisolDark chocolate also helps in reducing co - [Dysbiosis](https://www.elearning.dlife.in/lds-course-notes/dysbiosis-29/) - Notes: - [Sugar & Carb Addiction](https://www.elearning.dlife.in/lds-course-notes/sugar-carb-addiction-27/) - Notes:joslin: god of diabets..USPsycologist: - [The Role Of Nutrition In Human Health](https://www.elearning.dlife.in/lds-course-notes/the-role-of-nutrition-in-human-health-23/) - Notes:"Food is medicine " coined by Hippocrates the father of medicinehe said almost 2500 years ago " Leave your drugs in the chemist's pot if you can heal the patient with food " - [The Origin Of Carbohydrate Restriction In Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-origin-of-carbohydrate-restriction-in-chronic-diseases-14/) - Notes: - [Myth: Dietary Fat Causes Weight Gain](https://www.elearning.dlife.in/lds-course-notes/myth-dietary-fat-causes-weight-gain-22/) - Notes: - [The Metabolic Approach to Cancer: A Holistic and Evolving Paradigm](https://www.elearning.dlife.in/lds-course-notes/the-metabolic-approach-to-cancer-a-holistic-and-evolving-paradigm-6/) - Notes: Look up Dr. Nasha winters online for diet-oncology-rx.Metabolic Training Institute - Nasha Winters - [Myth: Plant Based Diets Are The Best](https://www.elearning.dlife.in/lds-course-notes/myth-plant-based-diets-are-the-best-34/) - Notes:Humans are omnivores - [Myth: Carbohydrates Are Essential](https://www.elearning.dlife.in/lds-course-notes/myth-carbohydrates-are-essential-43/) - Notes:Gluconeogenesis(GNG) - [Aldosterone](https://www.elearning.dlife.in/lds-course-notes/aldosterone-11/) - Aldosterone and Its FunctionsIntroduction: Aldosterone is a hormone that regulates sodium homeostasis, controlling blood volume and pressure. It plays a crucial role in sodium retention in the kidneys while helping to maintain blood pH balance through the regulation of electrolyte levels.Functions of Aldosterone Sodium and Water Balance:It retains sodium and excretes potassium in the kidneys.Blood pH: Aids in - [Diet Heart Hypothesis](https://www.elearning.dlife.in/lds-course-notes/diet-heart-hypothesis-28/) - Notes:The diet heart hypothesis postulates that reducing dietary saturated fat reduces serum cholesterol , thereby reducing the risk of cardiovascular disease . - [Adiponectin](https://www.elearning.dlife.in/lds-course-notes/adiponectin-11/) - Notes: Adiponectin is a protein hormone, also known as an adipokine, that is involved in regulating glucose levels and fatty acid breakdown. It is encoded by the ADIPOQ gene and is produced primarily in adipose tissue, but also in muscle and even in the brain. More than 9,000 publications indexed in PubMed focus on adiponectin action or - [Fructose](https://www.elearning.dlife.in/lds-course-notes/fructose-13/) - Notes: Robert Lustig lecture - revisit for Fructose metabolism - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-31/) - Notes: Gut Brain axis (GBA): Intricate connection between gastrointestinal health and neurological function.GBA integrates multiple systems including ENS, CNS, vagus nerve and other neural pathways and chemical mediators like hormones and neurotransmitters.As per recent research the gut microbiota plays significant role in influencing mental health, cognitive functions and various neurological disorders.Anatomy and Physiology of GBA:Neural - [Dietary Guidelines Myths & Facts](https://www.elearning.dlife.in/lds-course-notes/dietary-guidelines-myths-facts-28/) - Notes:Dietary Guidelines were first released in 19801990 U.S Congress passed the National Nutrition Monitoring and Related Research Act ..in section 301.HHS: Health and Human ServiceUSDA:United States of Agriculturethese two organisation jointly review,update' and publish the Dietaryb Guidelines in every 5 years.CEO of ADA(American Diabetes Association ) 2018-2021 ...low carb for managing diabetes. - [The Introduction to Dietary Guidelines.](https://www.elearning.dlife.in/lds-course-notes/the-introduction-to-dietary-guidelines-20/) - Notes: - [Non Alcoholic Fatty Liver Disease – NAFLD](https://www.elearning.dlife.in/lds-course-notes/non-alcoholic-fatty-liver-disease-nafld-13/) - Notes: ALT: 0-45 IU/LAST: 0-35IU/LAlkaline PO4ase: 30-120 IU/LGGT: 0-30 IU/LBilirubin: 2-17micromoles/LPT: 10.9-12.5secondsAlbumin: 40-60 g/L - [Adrenaline](https://www.elearning.dlife.in/lds-course-notes/adrenaline-14/) - Notes: Adrenaline is a hormone. It is produced in the adrenal medulla and in some neurons of the central nervous system. It is also known as epinephrine. Adrenaline and noradrenaline are separate identities but are related to hormones and neurotransmitters. Within a few minutes during a stressful situation, adrenaline is released into the bloodstream, sending - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-30/) - Notes: Vagus nerve -The primery neural conection is via Vagus nerve Sensory neurons -detects gut condition Motor neurons -affect digestion.neural pathways hormonal signaling microbiota influence immune mediation - [Alcohol](https://www.elearning.dlife.in/lds-course-notes/alcohol-9/) - Notes: Alcohol is an organic compound characterised by one or more hydroxyl (–OH) groups attached to a carbon atom in an alkyl group.Alcohols are classified into three types based on the position of the hydroxyl group: primary, secondary, and tertiary.Some alcohols can cause serious harm to humans. Ethanol, the most commonly consumed alcohol, directly affects DNA and - [Obesity Is A Metabolic Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-is-a-metabolic-disorder-18/) - Notes: watch again - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-24/) - Notes:Amylase: Important in digestion of carbohydrates. Amylase breaks down complex polysaccharides into simple absorbable forms.Found mainly in saliva and pancreas.One of the first enzyme interact with food setting the stage for the body's energy aquisition from carbs.Vital process of effective digestion.Types of AmylaseSalivary amylase and Pancreatic amylase.Salivary amylase (ptyalin): Secreted by the salivary glands. Digestion - [Protease](https://www.elearning.dlife.in/lds-course-notes/protease-18/) - Notes: Protease:each class of this enzymes employs different nucleophilis to attack peptide bonds.protease are found in pineapple and are used in baking and food production.proteases like trypsin and pepsin can also be taken as supplement form.classified according to catalytic mechanismaspartic proteasescysteine proteasesmetallo proteasesserine proteasesThreonine proteasesglutamic proteasesasparagine peptidases - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-27/) - Notes:Lipase is a crucial enzyme.It catalyzes the hydrolysis of triglycerides into free fatty acids and glycerol.Lipids are the fatty and waxy substances in the body that dont dissolve in water. (Phospholipid, Triglyceride, CholesteLipase is predominantly produce in pancreas but it also secreted by the mouth, stomach and intestines for digestion and absorption of dietary fats.Lipase - [Fats](https://www.elearning.dlife.in/lds-course-notes/fats-12/) - Notes: Fats are one of the three main macronutrients, alongside carbohydrates and proteins. Fats and oils are composed of molecules known as triglycerides, which are made up of three fatty acid units linked to glycerol. There are four types of fats: saturated, monounsaturated, polyunsaturated, and trans fats. It is important to note that no naturally occurring fat - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-12/) - Notes: Proteins are one of the three nutrients used as energy sources by the body, alongside carbohydrates and fats. Each protein and carbohydrate provides four energy calories per gram, while fats provide nine calories per gram. Proteins are incredibly versatile macromolecules that play essential roles in virtually all biological processes. This versatility arises from several primary properties - [The Current Situation](https://www.elearning.dlife.in/lds-course-notes/the-current-situation-25/) - Notes:Hyper Palatable Food:Engineered food containing combination of fat, sugar, sodium and carbohydrates at levels rarely found in nature. It is highly irresitable. Trigger intense pleasure signals in brain, overriding satiety cue and causing people to eat faster and in larger quantities. Reason for obesity and Fatty liver. - [Obesity Is A Metabolic Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-is-a-metabolic-disorder-17/) - Obesity is an enlargement of adipose tissue to store excess energy intake, which happens by two mechanisms, hypertrophy (increase in cell size) and hyperplasia (increase in cell number), with genetics and diet affecting the relative contributions of the two.The capacity to store fat has been a major adaptive factor of our species. Our body’s fat - [Insulin Resistance, Lipotoxicity & Energy Toxicity](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-lipotoxicity-energy-toxicity-9/) - Energy toxicity refers to a metabolic state characterized by the accumulation of excess energy, primarily stored as TGs in muscle and liver cells. With overload of energy, cells may resist further energy storage, leading to IR.Lipotoxicity refers to the harmful effects of excess tissue fat accumulation on glucose metabolism. Glucose is primarily stored in the liver and muscles - [Adipose Tissue](https://www.elearning.dlife.in/lds-course-notes/adipose-tissue-19/) - Adipose tissue (or fat tissue), composed primarily of adipose cells or adipocytes, is a lipid-storing type of loose connective tissue. It consists of large quantities of adipocytes and their precursors (preadipocytes) and some other cell types, all enclosed within a fibrous extracellular matrix that is well connected to blood and lymph vessels. Types of fat - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-90/) - We need food to fuel our bodies for energy, growth and repair. Our digestive system converts the foods we consume into the simplest forms - sugar (carbs), amino acids (proteins) and fatty acids and glycerol (fats). Broken down food is absorbed from the small intestine into the blood stream and carried to each cell in the - [The Rise of Modern Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-rise-of-modern-chronic-diseases-24/) - Notes:Chronic condition:1. Physical or Mental health condition that lasts more that 1 year.2. Causes functional restrictions3. Requires ongoing monitoring or treatment.*Prevalent and costly health condition in US*Approx 45% or 133 million of Americans suffered from at least one chronic disease.Chronic diseases:Cancer, Diabetes, Hypertension, Stroke, Heart disease, Respiratory diseases, Arthritis, Obesity and Oral Diseases. - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-61/) - Notes: HUMAN EVOLUTIONFrom Primates(group of mammals from which humans,monkeys and apes evolved)Primates >Apes>humans - [Carbohydrates](https://www.elearning.dlife.in/lds-course-notes/carbohydrates-15/) - Notes: Carbohydrates are vital molecules made up of carbon, hydrogen, and oxygen atoms, and they are classified as one of the three primary macronutrients, alongside protein and fat. ### The 3 Types of Dietary Carbohydrates Dietary carbohydrates are categorised into three main types: Sugars, Starches, and Fibres. - **Sugars**: These are sweet, short-chain carbohydrates found in various foods, including - [Body Fat Measurement](https://www.elearning.dlife.in/lds-course-notes/body-fat-measurement-9/) - Notes: Measuring body fat is essential for achieving a healthy body composition. Poor body composition, characterised by higher body fat and lower muscle mass, can lead to various health issues that affect a significant portion of the global population.There are several methods to assess body composition, including:1. Densitometry 2. Bod Pod 3. Skin-fold Calliper 4. Bioelectrical Impedance Analysis 5. Dual-Energy - [Food Intolerance & Allergy](https://www.elearning.dlife.in/lds-course-notes/food-intolerance-allergy-6/) - Notes: Food Intolerance, Food Allergy, Anaphylaxis, Common Allergy Triggers, and Food Poisoning are some of the Food Intolerance and Allergies. By and large, food intolerances are not life-threatening. Food Allergies are an overreaction of the body's immune system to a protein.In a few people, a food allergy that can trigger a severe allergic reaction is called Anaphylaxis.A - [Foods: The ‘Yes’, ‘May’ & ‘Never’ List](https://www.elearning.dlife.in/lds-course-notes/foods-the-yes-may-never-list-13/) - Notes: The sugar demon has 56 tricky names that compel you to buy in large quantities. Sugar is not only a drug but also toxic. Consuming fructose increases hunger and the desire for more food more than glucose does. Excessive fructose consumption may cause resistance to leptin.**Sugar is Toxic**Many people rely on quick, processed foods - [The Origin Of Carbohydrate Restriction In Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-origin-of-carbohydrate-restriction-in-chronic-diseases-7/) - Notes: Since ancient times, a low-carb diet has been used to treat diabetes. However, this approach has often been overlooked in favour of insulin and medications promoted by the pharmaceutical industry, which have profited significantly while compromising the health of diabetes patients. The low-carb dietary approach has a long-standing history, and it is once again - [Myth: PUFA Loaded Vegetable Oils Are Better Than Saturated Fat](https://www.elearning.dlife.in/lds-course-notes/myth-pufa-loaded-vegetable-oils-are-better-than-saturated-fat-14/) - Notes: Omega-6-rich polyunsaturated fatty acids (PUFAs) found in vegetable oils are often promoted as healthy options. However, since the introduction of these industrial vegetable oils into our diets, health has significantly declined. Many companies in India market various flavours of rice bran oil, often blended with sesame oil or other oils, labelling them as "Diabetes - [Myth: Saturated Fat Causes Heart Disease](https://www.elearning.dlife.in/lds-course-notes/myth-saturated-fat-causes-heart-disease-13/) - Notes:**Vilification by the PUFA Vegetable Oil Industry**The vilification of saturated fat began with Procter & Gamble when they developed synthetic trans fats, specifically a toxic fat marketed under the name CRISCO. This company has waged an all-out war against coconut oil to promote their harmful product. In India, a similar version called DALDA, along with - [Myth: Proteins Cause Kidney Damage](https://www.elearning.dlife.in/lds-course-notes/myth-proteins-cause-kidney-damage-9/) - Notes: **The General Belief** The idea that higher protein diets cause kidney disease has been around for at least 50 years. It is often repeated that excessive protein consumption harms the kidneys. However, this is only true for individuals with existing kidney or liver conditions. Healthy kidneys are quite adept at eliminating the extra nitrogen that comes - [Myth: Plant Based Diets Are The Best](https://www.elearning.dlife.in/lds-course-notes/myth-plant-based-diets-are-the-best-17/) - Notes: **Vegetarian vs. Vegan Diets**It's important to note that vegetarianism is not the same as veganism. Vegetarians come in several variations: - **Ovo-Vegetarians** eat eggs. - **Lacto-Vegetarians** consume dairy products but do not eat eggs. - **Ovo-Lacto-Vegetarians** eat both eggs and dairy products. - **Pescatarians** eat fish but no other animal products. On the other hand, vegans abstain from all animal-derived - [Myth: Carbohydrates Are Essential](https://www.elearning.dlife.in/lds-course-notes/myth-carbohydrates-are-essential-21/) - Notes: **The 3 Macronutrients: A Comprehensive Overview**Human food intake can be divided into two main categories: macronutrients and micronutrients. The three macronutrients are carbohydrates, proteins, and fats, while micronutrients include vitamins, minerals, and other food supplements, totalling over 50 types – some essential and others non-essential.Of the three macronutrients, proteins and fats are truly essential - [Diet Heart Hypothesis](https://www.elearning.dlife.in/lds-course-notes/diet-heart-hypothesis-12/) - Notes: The diet-heart hypothesis suggests that reducing dietary saturated fat lowers serum cholesterol levels, which in turn decreases the risk of cardiovascular disease. This idea has evolved from a hypothesis into public health policy, with current guidelines recommending a reduction in dietary saturated fat intake.Dr Ancel Keys first proposed the diet-heart hypothesis in the 1950s. - [American Diabetes Assn – Low Carb & Very Low Carb Diet For Diabetes](https://www.elearning.dlife.in/lds-course-notes/american-diabetes-assn-low-carb-very-low-carb-diet-for-diabetes-10/) - Notes: The American Diabetes Association (ADA) is a nonprofit organisation based in the U.S. that seeks to educate the public about diabetes and assist those affected by it by funding research aimed at managing, curing, and preventing the disease. As a leading diabetes association, the ADA has considerable influence over guidelines worldwide.Historically, the ADA has opposed - [The Latest Eat Lancet](https://www.elearning.dlife.in/lds-course-notes/the-latest-eat-lancet-12/) - Notes: The Lancet, in partnership with EAT, is a non-governmental advocacy group based in Norway. They have established a commission called eatforum.org, which includes more than 30 world-leading scientists from around the globe. Their goal is to develop recommendations for a sustainable, healthy diet supported by a sustainable food system.Food systems have the potential to promote - [How The Dietary Guidelines Evolved](https://www.elearning.dlife.in/lds-course-notes/how-the-dietary-guidelines-evolved-4/) - Notes:1992 Food Guide PyramidThe introduction of the USDA's Food Pyramid aimed to express the recommended serving sizes for each food group, a feature absent from earlier guides. It was developed using consumer research to help bring awareness to the new food patterns. Suggestions that were included are:01) 06 to 11 servings of bread, cereal, rice, - [The Introduction to Dietary Guidelines.](https://www.elearning.dlife.in/lds-course-notes/the-introduction-to-dietary-guidelines-9/) - Notes: Despite the deteriorating health trends ranging from the incidences of higher obesity rates in women and childhood obesity rates in boys and cancer deaths across the world, both the Food and Pharma industries have succeeded in dumping their products with the support ofthe USDA on the pretext of treating their sayings as VEDAS for - [Dietary Guidelines Myths & Facts](https://www.elearning.dlife.in/lds-course-notes/dietary-guidelines-myths-facts-11/) - Notes: **CardioDiabesity: An Epidemic**CardioDiabesity is an umbrella term that encompasses Cardiovascular Disease, Diabetes, and Obesity—three key health issues influenced by Insulin Resistance. For over 40 years, the USDA dietary guidelines have failed to address these problems effectively. As a result, many countries that have followed these guidelines are witnessing a rise in CardioDiabesity globally.**Global Impact**- - [Protease](https://www.elearning.dlife.in/lds-course-notes/protease-10/) - Notes: **Proteases and Their Importance**Proteases are enzymes that break down proteins and constitute nearly 2% of the human genome, making them a significant class of enzymes. They play crucial roles in various biological processes, including development, differentiation, cell migration, immune response, wound healing, and cell death.**Biological Roles of Proteases**- **Digestion**: They catalyse the hydrolysis of - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-15/) - Notes: Amylase is an essential enzyme for carbohydrate digestion, as it breaks down complex polysaccharides into simpler forms. It is primarily found in saliva and the pancreas and is one of the first enzymes to interact with food. Amylase plays a crucial role in the body's energy extraction and effective nutrient absorption in humans and other - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-17/) - Notes: Lipase is an essential enzyme that catalyses the hydrolysis of triglycerides into free fatty acids and glycerol, playing a crucial role in digestion and lipid metabolism across various organisms. Primarily produced in the pancreas, lipase is also secreted by the mouth, stomach, and intestines, highlighting its significance in digesting dietary fats.### Types of Lipases1. - [The Current Situation](https://www.elearning.dlife.in/lds-course-notes/the-current-situation-11/) - Notes:### Hyperpalatable Food: A Major ConcernThe current generation is drawn to hyper-palatable, ultra-processed junk food, which is the root cause of many modern chronic diseases. This impact is particularly evident in school-aged children, many of whom are now obese. A significant number of them are also affected by Non-Alcoholic Fatty Liver Disease (NAFLD), a condition - [The Rise of Modern Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-rise-of-modern-chronic-diseases-8/) - Notes: A chronic deteriorating health condition is defined as a physical or mental health issue that persists for more than one year and leads to functional restrictions or requires ongoing monitoring or treatment. Chronic diseases include cancer, diabetes, hypertension, stroke, heart disease, respiratory diseases, arthritis, obesity, and oral diseases. These conditions can result in hospitalisation, long-term disability, - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-25/) - Notes: Humans began cultivating agriculture and crops nearly 10,000 years ago. Historians indicate that between 10,000 and 14,000 years ago, the primary staple food, rice, was domesticated and cultivated in Southeast Asia. - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-27/) - Notes: **Notes on Human Evolution and Diet:** Human evolution began with apelike ancestors and occurred over approximately 6 million years. The development of agriculture and the rise of the first civilisations took place within the last 12,000 years. The first significant change in the human diet involved the incorporation of meat and marrow from large animals, which started - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-60/) - Notes: Average human brain volume:- 1350cm cube. - [Introduction To Anthropometry](https://www.elearning.dlife.in/lds-course-notes/introduction-to-anthropometry-9/) - Notes: Anthropometry, or Anthropometrics, is the study of human body measurements. A few common anthropometric measurements include height, weight & circumference. A few health indicators include (1) Ideal Body Weight (IBW). (2) Body Mass Index (BMI). (3) Waist/Hip Ratio (WHR), (4) Waist Circumference. (5) Waist To Height Ratio (WHR). (6) Body Composition.BMI is a faulty concept as - [Dysbiosis](https://www.elearning.dlife.in/lds-course-notes/dysbiosis-11/) - Notes: Dysbiosis, the term itself exhibits, is a disruption to the gut microbiota caused by an imbalance in the microflora, changes in their functional composition and metabolic activities, or a shift in their local distribution. In other words, an imbalance in the microbiota can cause dysbiosis. When dysbiosis happens in your Gastrointestinal tract, it is typically - [Sugar & Carb Addiction](https://www.elearning.dlife.in/lds-course-notes/sugar-carb-addiction-11/) - Notes: The three primary elements that make sugar addictive are its hedonic value, reinforcement, and palatability. Sugar works as an attributable silent killer in our brain's reward system.Moreover, the food industry is more focused on adding sugar to every eatery item merely on the ill-fated grounds of entertainment and not nutrition. There are several ways to - [The Role Of Nutrition In Human Health](https://www.elearning.dlife.in/lds-course-notes/the-role-of-nutrition-in-human-health-9/) - Notes: The state of being healthy illustrates that putting the right fuel takes precedence over any indecisive conclusions. Whole foods have the power to protect the sanctity of our bodily system. The tasty, palatable foods that appear on the racks of shopping malls ruin your health with a hidden agenda of getting you into the Pharma - [Myth: Dietary Fat Causes Weight Gain](https://www.elearning.dlife.in/lds-course-notes/myth-dietary-fat-causes-weight-gain-10/) - Notes: Obesity is one of the biggest health problems in the world. The food industry often shifts the blame onto consumers for the rising rates of obesity globally. With significant investments in the food business, these companies prioritise the interests of their shareholders over those of consumers. **Calorie In, Calorie Out Model of Obesity** The "calorie in, calorie - [Carbohydrates](https://www.elearning.dlife.in/lds-course-notes/carbohydrates-34/) - Notes: - [Understanding Autoimmune Conditions, and the Role of Carnivore Diet in Management](https://www.elearning.dlife.in/lds-course-notes/understanding-autoimmune-conditions-and-the-role-of-carnivore-diet-in-management-12/) - Notes: - [Hypertension Medications](https://www.elearning.dlife.in/lds-course-notes/hypertension-medications-8/) - Notes: - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-23/) - Notes: - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-26/) - Notes:Lipase - crucial enzymes that catalyzes the hydrolysis of triglycerides into free fatty acids and glycerolvital role in lipid metabolism and digestion across various organisms.lipase enzyme is predominantly produced in the pancreas( Pancreatic Lipase) , but also secreted by the mouth (Lingual Lipase),stomach (gastric Lipases) and instestines,for digestion and absorption of dietary fats. - [Insulin Resistance & NAFLD](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-nafld-25/) - Non-alcoholic fatty liver disease (NAFLD) is a very common condition where excess fat builds up in the liver without heavy alcohol use. It can progress to more severe forms like non-alcoholic steatohepatitis (NASH), which involves liver inflammation and damage, potentially leading to scarring (fibrosis), cirrhosis, and liver failure.Obese adipose tissues are resistant to the anti-lipolytic - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-91/) - Notes:Lower esophageal sphincter--ring like muscle--its a gate ...lets food paas into stomach and prevent flowing back into esophagus.stomach--chymesmall instestine --food mix with digestive juices from pancreas,liver...further digestion ...absorb water and digested nutrients into the blood stream...large intestine - waste products from digestion ...absorbs water...stool...Peristalsis movement.saliva --enzymes --breakdown starches...in the mouth...stomachamylase--mouth -ptyalin-in salivary gland -acts on - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-64/) - Notes:Rice-southeast asia -10,000to14,000 years ago wheat -8000bc south iran and southeastern Turkeywheat reaches india around 6500BCthen its increased in the production of wheat as demand rises..so 99.99% our genetic pattern formed ...humans are yet to adapt this sudden influx of grain in our diet in last 10,000 yearsegyptians invent bread and baking process.....recorded case - [Metabolic Disorder — Current Indian Data](https://www.elearning.dlife.in/lds-course-notes/metabolic-disorder-current-indian-data-8/) - Metabolic disorders are increasingly prevalent in India. They are interrelated, often co-occurring and exacerbating each other’s progression. E.g., IR is a common feature in both obesity and PCOS, contributing to the development of T2D and CVD.Obesity – Prevalence of Obesity: 28% (higher prevalence in urban areas) and Abdominal Obesity: 39% (strongly associated with MetS).Diabetes – - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-17/) - Notes: **The Crucial Role of Gut Microbiota in Mental Health and Neurological Disorders**II. **Anatomy and Physiology of the Gut-Brain Axis** A. **Neural Pathways** B. **Hormonal Signaling** C. **Influence of Microbiota** D. **Immune Mediation** III. **Autonomic Nervous System (ANS)** A. **Definition and Role** B. **Branches of the ANS** 1. **Sympathetic Nervous System (SNS)** - [LIPID Peroxidation & Neurological Disorders](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-neurological-disorders-10/) - The brain's high oxygen consumption, abundant PUFA, and relatively low antioxidant defenses make it particularly vulnerable to oxidative damage. LPO is implicated in the following neurological conditions:Alzheimer's Disease (AD) - Elevated levels of HNE are observed in AD, which modifies amyloid precursor proteins, promoting aggregation of β-amyloid plaques. Oxidative damage exacerbates synaptic dysfunction, neuroinflammation, and neuronal - [LIPID Peroxidation & Diabetes](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-diabetes-10/) - LPO contributes to the pathogenesis and complications of diabetes through multiple mechanisms.Pancreatic β-Cell Dysfunction – β-cells have low intrinsic antioxidant capacity, so are particularly vulnerable to damage caused by ROS and LPO products. Damage to membrane lipids disrupts insulin granule exocytosis and reduces insulin biosynthesis, exacerbating hyperglycemia.IR – HNE and other LPO products interfere with - [LIPID Peroxidation & Cardiovascular Disease (CVD)](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-cardiovascular-disease-cvd-13/) - LPO plays a crucial role in the development and progression of CVD, particularly atherosclerosis, through oxidative stress, inflammation, and direct damage to vascular components.Atherosclerosis is characterized by the accumulation of oxidized LDL (oxLDL) within arterial walls. oxLDL promotes endothelial dysfunction, inflammatory responses, and the recruitment of immune cells, which exacerbate plaque formation and instability. LPO - [LIPID Peroxidation](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-13/) - Lipid peroxidation (LPO) is a complex biochemical process that leads to the oxidative degradation of lipids, particularly PUFAs derived from linoleic acid. It is a critical, dual-faceted aspect of cell physiology, acting as both a vital signaling mechanism at low levels and a destructive, pathological process when uncontrolled. The process is significant both in biological - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-32/) - Notes: The human digestive system begins at the mouth and ends at the anus. It resembles a muscular tube that can be up to 10 meters long, with various digestive organs, including the mouth, oesophagus, stomach, small intestine, large intestine, and anus attached along its length. The solid organs associated with the digestive system are - [Navigation Flow Sequence](https://www.elearning.dlife.in/lds-course-notes/navigation-flow-sequence-14/) - Notes: - [Cholesterol & Its Functions](https://www.elearning.dlife.in/lds-course-notes/cholesterol-its-functions-19/) - Cholesterol is essential for all animal life and if there is no cholesterol, there is no life. Each cell is capable of synthesizing it by way of a complex 37-step process. Most of cholesterol (waxy substance) is made by the liver and the rest comes from dietary sources like meat, poultry, eggs, fish, and dairy products (plant - [Recipe & Diet Plan Posting](https://www.elearning.dlife.in/lds-course-notes/recipe-diet-plan-posting/) - Notes: - [TOFI – Thin Outside Fat Inside – Obesity](https://www.elearning.dlife.in/lds-course-notes/tofi-thin-outside-fat-inside-obesity-14/) - Notes: - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-29/) - Notes:GI = Gastrointestinal - [High Intensity Interval Training – HIIT](https://www.elearning.dlife.in/lds-course-notes/high-intensity-interval-training-hiit-10/) - HIIT involves performing exercises at near-maximal intensity (80-100% of max HR) for short durations, typically ranging from 15 sec to 4 min, followed by recovery intervals that may include low-intensity activity or complete rest. The work-to-rest ration can vary, but a common structure is a 2:1 ratio, such as 30 sec of intense exercise followed - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-59/) - Notes:human ev0lution begin with the primates.Human and Cimps sepraterd 7.5MLA The sumerians of Mesopotamia develop the world's firet civilazation . - [Magnesium](https://www.elearning.dlife.in/lds-course-notes/magnesium-26/) - Magnesium is a foundational and abundant mineral powering many of the body’s most critical systems.Function – Cofactor in >300 enzyme systems that regulate diverse reactions includingcarbohydrate metabolismenergy production (ATP generation from both carbs and fat)protein synthesistranscellular ion transport – active transport of calcium/potassium ions across cell membranes (important for nerve impulse conduction, muscle contraction/relaxation, BP regulation/vasomotor - [Pull Exercise](https://www.elearning.dlife.in/lds-course-notes/pull-exercise-5/) - The primary muscles in a pull workout include all back muscles, biceps, hamstrings, obliques, and trapezius.There are benefits to all lifting routines (including muscle dividing days), however, it’s not for everyone. Simple Push/Pull routine works for everyone because it creates muscle balance, dividing our muscles into different days can lead to imbalance. The most common - [Push Exercise](https://www.elearning.dlife.in/lds-course-notes/push-exercise-4/) - Push UpsSquats - Squatting is the most natural movement that comes to us as Human Beings. A squat is simply sitting down as much as you can go and then exploding up. Squatting should be approached by beginners by first performing bodyweight squats with achieving and being comfortable with the full range of motion performing - [Anabolic Resistance](https://www.elearning.dlife.in/lds-course-notes/anabolic-resistance-11/) - Metabolism is a combination of two biochemical phenomena, anabolic and catabolic reactions/processes.Anabolic resistance refers to the diminished capacity of muscles to synthesize protein effectively, hampering muscle growth, in response to anabolic stimuli, such as protein intake and resistance exercise. This condition is a significant factor in the aging process, leading to a decline in muscle mass - [Cardiac Arrhythmia](https://www.elearning.dlife.in/lds-course-notes/cardiac-arrhythmia-12/) - Notes:CARDIAC ARRHYTHMIA IS A CONDITION WHERE THE HEART RATE OR RHYTM IS ABNORMAL IN NORMAL ADULTS THE HEART RATE IS 60 TO 100 PER MINUTESTYPES OF ARRHYTHMIA-TACHYCARIDA- HEART RATE ABOVE 100 FAST HEART RATEBRADYCARDIA- HEART RATE BELOW 60 SLOW HEART RATEARRHYTMIA IS CAUSED DUE TO THE CHANGES TO THE HEART TISSUE IT CANALSO OCCUR SUDDENLY DUE TO - [Excess Post-exercise Oxygen Consumption (EPOC)](https://www.elearning.dlife.in/lds-course-notes/excess-post-exercise-oxygen-consumption-epoc-9/) - Excess Post-exercise Oxygen Consumption (EPOC), also known as oxygen debt, is the physiological effect where the body’s metabolism continues to burn more calories post exercise than when at complete rest. EPOC is the amount of oxygen required to restore the body to its normal, resting level of metabolic function (called homeostasis).EPOC is the body’s response - [Muscle Gain](https://www.elearning.dlife.in/lds-course-notes/muscle-gain-12/) - Important points for macronutrient calculations for muscle gain for males:If current weight is less than IBW range, use current weight or IBW ??If within IBW range: If he is lean/muscular, use current weight. If he carries fat, slightly higher WHR, use LBM considering 15% body fat.If higher than IBW range: If he is lean/muscular, use - [Weight Loss](https://www.elearning.dlife.in/lds-course-notes/weight-loss-12/) - Lean Body Mass – LBM. Body Weight – BW.Ideal Body Weight – IBW: Range is +/- 5 kgs.Male: Height (cm) – 100Female: (Height (cm) – 100) – 10%IntensityBeginner - One living sedentary lifestyle and just starting.Intermediate - One exercising 3 times a week.Advanced - One lifting weight and running miles for 6 days a week.Important - [Diet And Supplement Planning Goals](https://www.elearning.dlife.in/lds-course-notes/diet-and-supplement-planning-goals-14/) - Vitamins & Minerals for Sports NutritionB Complex Vitamins – Sports Nutrition Requirement: 12-200 mcg/day.Vitamin E can prevent muscle cramps esp. for athletes during workout.Vitamin CMagnesium – Mg and Ca use the same absorption pathways and thus can interfere in each other’s absorption. However, Ca:Mg 1:1 can work well and not cause any absorption issues. The - [The Randle Cycle: Understanding the Glucose-Fatty Acid Cycle](https://www.elearning.dlife.in/lds-course-notes/the-randle-cycle-understanding-the-glucose-fatty-acid-cycle-10/) - The Randle cycle, also known as the glucose fatty-acid cycle, is a metabolic process involving the cross inhibition of glucose and fatty acids for substrates (for oxidation and uptake). It operates primarily in muscle and adipose tissue, where it adds a nutrient-mediated fine tuning (as per substrate supply and demand) on top of the coarser - [AMPK Pathway](https://www.elearning.dlife.in/lds-course-notes/ampk-pathway-21/) - The Adenosine Monophosphate (AMP) activated Protein Kinase (AMPK) pathway and the mTOR pathway are the antagonists of each other. AMPK is a major contributor to catabolic metabolism and AMPK activated catabolism is extremely important and beneficial for the body. It is a master regulator of cellular energy homeostasis. Functions:Fat oxidation – AMPK increases the activity - [Aerobic Energy System](https://www.elearning.dlife.in/lds-course-notes/aerobic-energy-system-19/) - Aerobic Energy System, also known as oxygen system or oxidative system or cellular respiration or aerobic glycolysis, is a method for producing sustainable ATP during day-to-day activities and low-to-moderate intensity exercises. It includes Glycolysis, the Krebs Cycle, and Oxidative Phosphorylation, which includes the Electron Transport Chain. Glycolysis occurs in the cytoplasm (outside the mitochondrion) and - [Ketogenic Diet](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-21/) - The ketogenic diet started as a special diet designed to help children with epilepsy that fails to respond adequately to routine anti-epileptic medications.The primary focus of a ketogenic diet is to achieve the state of Nutritional Ketosis, which signifies that the body is running on fat as its primary source of fuel, and one is - [Three States Of Ketosis](https://www.elearning.dlife.in/lds-course-notes/three-states-of-ketosis-17/) - Ketogenesis is the metabolic pathway that produces ketone bodies. Ketones can convert to acetyl-CoA and go through the Krebs cycle and oxidative phosphorylation, thereby produce 22 ATP per ketone molecule. The body is constantly producing small amounts of ketone bodies, which is regulated mainly by insulin. In a state of ketosis, ketone body production is - [The Easy Transition Plan](https://www.elearning.dlife.in/lds-course-notes/the-easy-transition-plan-10/) - Notes: - [Lactic Acid Energy System](https://www.elearning.dlife.in/lds-course-notes/lactic-acid-energy-system-16/) - Lactic Acid Energy System, also known as lactacid system or anaerobic glycolysis or glycolytic system, utilizes glycogen stores (in the liver and muscles) to generate ATP.Oxygen not needed (anaerobic)Fuel source: Glycogen2-3 ATP / Glucose moleculeFast productionFor high intensity of activity (>85% of max HR) – 400m run, high-rep liftingFor 10-75 secondsHappens outside the mitochondrionMechanism of - [Krebs Cycle](https://www.elearning.dlife.in/lds-course-notes/krebs-cycle-19/) - The Krebs cycle, or the citric acid cycle or the tricarboxylic acid cycle (TCA cycle), is a central metabolic hub in cellular respiration, occurring in the mitochondrial matrix. One cycle consumes 1 acetyl-CoA derived from food molecules and 2 water molecules, reduces 3 NAD+ to 3 NADH, reduces 1 FAD to 1 FADH2, generates 1 - [ATP-PC Energy System](https://www.elearning.dlife.in/lds-course-notes/atp-pc-energy-system-17/) - ATP-PC energy system, also known as phosphocreatine (PC/PCr) or creatine phosphate (CP) or phosphagen or alactic system, utilizes phosphate group of PC/PCr/CP (names for the same chemical) to convert ADP into ATP.Oxygen not needed (anaerobic)Fuel source: Stored ATP and PC0.7 ATP / PC moleculeInstantaneous production due to simple chemical reactions and only a few stepsFor - [Managing LCHF In Social Functions](https://www.elearning.dlife.in/lds-course-notes/managing-lchf-in-social-functions-6/) - Notes:IN AN EVENT START WITH FIBER AND THEN COMBINE IT WITH PROTIEN AND THEN VEGETABLES AND THEN SWEETSALSO FOR SWEETS AVOID ANY LIQUID SWEETS AND SWEETS MADE WITH WHEAT,RAWA,MAIDA ETCAND THEN WALK AND MOVE ALOT AFTER A HEAVY CARB MEALALSO FIRST CALM DOWN YOUR NERVOUS SYSTEM BY DOING SOME BREATHING EXCERCISE BEFORE EATING TO PREVENT - [Ketogenic Diet For Alzheimer’s Disease](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-for-alzheimers-disease-10/) - Notes: - [Adenosine Triphosphate – ATP](https://www.elearning.dlife.in/lds-course-notes/adenosine-triphosphate-atp-20/) - Adenosine triphosphate (ATP) is a nucleotide consisting of an adenine base attached to a ribose sugar, which is attached to three phosphate groups. Phosphate groups are linked to each other by high-energy phosphoanhydride bonds, breaking of which is an exothermic reaction. Energy is released when ATP loses one or two phosphate groups. Adenosine diphosphate (ADP) - [Inflammation](https://www.elearning.dlife.in/lds-course-notes/inflammation-23/) - Inflammation is a complex fabric of signals and cellular responses from our immune system that enables our bodies to recognize and respond to infection and injury. Having too weak of an inflammatory response leaves us prone to infection or impaired healing. But having too great a response, or one that remains over-active for too long, - [mTOR Pathway](https://www.elearning.dlife.in/lds-course-notes/mtor-pathway-27/) - The mammalian target of rapamycin or the mTOR is a serine/threonine protein kinase. mTOR pathway is a part of the phosphatidylinositol 3-kinase (PI3K) pathway, a family of lipid kinases involved in cell growth, survival, and proliferation. mTOR nucleates at least two distinct multi-protein complexes – mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2).mTOR controls - [Learning System Overview](https://www.elearning.dlife.in/lds-course-notes/learning-system-overview-10/) - Notes: - [Dehydration & Sodium Importance in Sports](https://www.elearning.dlife.in/lds-course-notes/dehydration-sodium-importance-in-sports-20/) - Glycogen in muscle, liver, and fat cells is stored in a hydrated form, composed of 3-4 parts of water per part of glycogen with 18 mg of potassium per gram of glycogen. While transitioning from High Carb to Low Carb diets, there is a drastic reduction of carb intake, leading to less glycogen storage and - [The Role of Exercise](https://www.elearning.dlife.in/lds-course-notes/the-role-of-exercise-8/) - Notes: - [Understanding Migraines: Causes, Connections, and Management](https://www.elearning.dlife.in/lds-course-notes/understanding-migraines-causes-connections-and-management-9/) - Notes:MIGRAINES CAUSES -GLUCOSE INTOLERANCEELECTROLYTE IMBALANCE [ SODIUM PLAYS AN IMP ROLS ]STRESS HORMONES AND GLUCOSEMITOCHONDRIAL DYSFUNCTION - [Ketogenic Diet For Alzheimer’s Disease](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-for-alzheimers-disease-9/) - Notes:AN INDIVIDUAL WITH ALZHEIMERS DISEASE , THIER BRAINS ABILITY TO UTILIZE GLUCOSE AS AN ENERGY SOURCE DIMINISHES HOWEVER THE BRAIN CAN EFFECTIVELY USE KETONES WHICH ARE PRODUCED DURING FAT METABOLISM WHEN CARBS INTAKE IS LOWTHIS SHIFT TO KETONE METABOLISM MAY HELP RESTORE ENERGY BALANCE IN THE BRAIN , SLOWING IMPROVING ITS FUCTIONS - [Water & Electrolytes](https://www.elearning.dlife.in/lds-course-notes/water-electrolytes-18/) - Water - ~60% of body weight in adult men. Most of the organs and tissues contain >70% water: blood and kidneys consist of 83% water and muscles 76% water. However, adipose tissue consists of only 10% water. Two-third of the body water is intracellular. The extracellular fluid consists of plasma and interstitial fluid. Ingested water - [Dietary Guidelines Myths & Facts](https://www.elearning.dlife.in/lds-course-notes/dietary-guidelines-myths-facts-26/) - Notes: - [Three Pillars Of Fitness](https://www.elearning.dlife.in/lds-course-notes/three-pillars-of-fitness-15/) - Three Pillars of FitnessCardiovascular Exercise – boosts heart rate, works respiratory system and increases circulation. E.g. walking, jogging, running, swimming, cycling, hiking, jumping rope, martial arts, boxing, rowing, elliptical cross-training, Stairmaster.Resistance/Strength/Weight Training – working out with free weights, resistance bands, weight machines, medicine balls and using own body strength with exercises such as push-ups, lunges, - [Heart Attack](https://www.elearning.dlife.in/lds-course-notes/heart-attack-14/) - Notes: - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-56/) - 1. First human trait bipedalism-the ability to walk omen two legs-4 million years agolarge brains, ability to make tools,capacity for languagecomplex symbolic expressions,art,cultural diversity emerged past 100000 yearshumans are primates related to apes- with - [Iron Profile Test](https://www.elearning.dlife.in/lds-course-notes/iron-profile-test-9/) - Notes:IRON PROFILE TEST - COMPONENTS - SERUM IRON - IT MEASURES THE AMOUNT OF IRON IN THE BLOOD THATS BOUND TO TRANSFERRIN [ A CRUCUIAL BLOOD PROTEIN MAINLY MAID IN THE LIVER TO BIND TO IRON TO TRANSFER IT TROUGHOUT OUR BODY ]. LOW LEVELS - [Vitamin A](https://www.elearning.dlife.in/lds-course-notes/vitamin-a-23/) - Notes: - [Kidney Function Test (KFT)](https://www.elearning.dlife.in/lds-course-notes/kidney-function-test-kft-11/) - Notes:GLOMERULI - FILTERING UNITS OF THE KIDNEYTYPES OF KIDNEY FUNCTION TEST - KFTGLOMERULAR FILTRATION RATE - GFR IS A KEY INDICATOR OF KF, MEASURING THE RATE AT WHICH THE BLOOD IS FILTERED THROUGH THE GLOMERULINORMAL GFR FOR ADULTS IS BET 90 - 120ML/MIN - [Complete Blood Count (CBC) Tests](https://www.elearning.dlife.in/lds-course-notes/complete-blood-count-cbc-tests-14/) - Notes:CBC - COMPLETE BLOOD TESTWHITE BLOOD CELLS COUNT - [WBC] THIS IS CRUCIAL FOR FIGHTING INFECTIONSRED BLOOD CELLS - [RBC] RESPONSIBLE FOR TRANSPORTING OXYGEN THROUGHOUT THE BODYHEMOGLOBIN [HB] - BLOOD CELLS CARRIES OXYGEN , LOW LEVELS CAN INDICATE ANEMIAHEMATROCIT - THIS IS MADE OF BLOOD VOLUME THAT IS MADE UP OF RED BLOOD CELLSPLATELET COUNT - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-63/) - Wheat is the 3rd most produced cereal after maize and rice - leading source of vegetable protein. Around 99.99% of our genetic pattern formed before the onset of agriculture and humans are yet to completely adapt to agricultural produce (~10,000 years). Egyptians are the first known humans to have made bread out of wheat - also the - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-60/) - Physical and behavioural traits shared by all people originated from ape ancestors, likely evolved over a period of 6 million years.Bipedalism likely evolved over 4 million years ago. Humans first evolved in Africa; oldest fossils dating back 2-6 million years ago come wholly from Africa.We share a common ancestor with other great apes - chimpanzees, bonobos - [Insulin Resistance & Diabetes](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-diabetes-25/) - Notes:TYPE 1- type one diabetes is a condition in which your immune system destroys insulin making cells called as beta cells. this condition usually occurs in children and young people and they have to be dependent on outside insulin for sugar controlTYPE 1.5[LADA]-latent autoimmune diabetes in adults this type is similar to type-1. this is an - [PCOS – Polycystic Ovarian Syndrome](https://www.elearning.dlife.in/lds-course-notes/pcos-polycystic-ovarian-syndrome-19/) - Notes:PCOS IS WHEN OUR OVARIES PRODUCE MORE OF A MALE HORMONE WHICH IS ADROGEN TESTOSTERONES MAIN IS ADROGENAND THIS CAUSES IMBALANCE IN OTHER HORMONESALSO THERE MAY BE OCCURENCE OF CYST ON OUR OVARIES AND THEY MAYBE NONHARMFULIR PCOS- THIS IS MOST COMMON TYPE OF PCOS . IN THIS TYPE PCOS IS CAUSED BY SOKING,POLLUTION,SUGAR AND TRANS FATTO - [Insulin Test – Setting The Bar Right](https://www.elearning.dlife.in/lds-course-notes/insulin-test-setting-the-bar-right-18/) - Notes:THE SAFE LIMIT FOR FASTING INSULIN IS UP TO 6 OR IDEALLY 7 MAXTHE FIRST THING THAT WE SHOULD LOOK FOR IN THE CLIENTS IS THE FASTING INSULIN AND THE POSTPRANDIAL INSULIN LEVELS WHICH SHOULD BE A BASIS OF MOVING TO LCHF DIET - [Introduction To Anthropometry](https://www.elearning.dlife.in/lds-course-notes/introduction-to-anthropometry-20/) - Notes:IDEAL WEIGHT FOR MEN[IBW]=HIEGHT-100IDEAL WEIGHT FOR WOMEN=[HEIGHT-100]-10%WAIST TO HIP RATIO=WAIST MEASUREMENT DIVIDED BY HIP MEASUREMENT - [Cholesterol & Its Functions](https://www.elearning.dlife.in/lds-course-notes/cholesterol-its-functions-18/) - Notes:HDL, LDL - mmol/L to mg/dL multiply by 38.67HDL, LDL - mg/dL to mmol/L multipley by 0.02586TG - mmol/L to mg/dL multiply by 88.57TG - mg/dL to mmol/L multiply by 0.01129 - [20 Common Mistakes On LCHF / Keto Diet](https://www.elearning.dlife.in/lds-course-notes/20-common-mistakes-on-lchf-keto-diet-16/) - Not eating enough – by cutting carbs and eating protein and fat (more filling than carbs), you could feel fuller with eating less and could end up not eating enough. Make sure to not go below 1,200 calories to avoid going into starvation mode and lose precious muscle mass-that would slow down metabolism, which would - [LCHF Diet](https://www.elearning.dlife.in/lds-course-notes/lchf-diet-22/) - One study concluded that at 20% max carbs, saturated fat has no relation for CVD.Low carb: 50-100 g carb per day.Ideal composition for a 2,000-kcal LCHF diet:Carb: 75-100 g (15-20%), max 20% and max 100 g whichever is lower.Protein: 100-125 g (20-25%), min 20% and min 100 g whichever is higher. Carb & protein combined - [Carnivore Diet](https://www.elearning.dlife.in/lds-course-notes/carnivore-diet-14/) - Dr. Shawn Baker, 55+-year-old trained orthopedic surgeon who lifts weights, is the unofficial Carnivore King.Allowed:MeatFishOther animal products including eggs, lard, bone marrow, bone broth.Low-lactose dairy (in small amounts) including heavy cream, hard cheese, butter, etc.WaterAccording to some proponents of the diet, salt, pepper, and seasonings with no carbs are allowed.Not Allowed - any food not - [The Atkins Diet](https://www.elearning.dlife.in/lds-course-notes/the-atkins-diet-19/) - The Atkins diet was primarily a weight loss diet, Dr, Robert C. Atkins proposed eating as much protein and fat as you wanted, as long as foods in high carbs were completely avoided. Though not looking at macros, it emphasizes the word low carb. Involves 4 phases:Phase 1: Induction (2 weeks) – Eat high-fat, high-protein, - [Vasodilators](https://www.elearning.dlife.in/lds-course-notes/vasodilators-11/) - Notes:VASOLIDATORS ARE MEDICINE THAT DILATE[WIDEN] BLOOD VESSELS,ALLOWING BLOOD TO FLOW MORE EASILY THROUGH.BRAND-HYDRALAZINE- PLAIN HYDRA IS NA IN INDIA, USUALLY AVA ONLY IN COMBI WITH OTHER DRUGS - [Diuretics](https://www.elearning.dlife.in/lds-course-notes/diuretics-11/) - Notes:DIURETICS ALSO CALLED AS THE WATER PILLSDIURETUCS HELP OUR KIDNEYS ELIMINIATE EXCESS SALT AND WATER FROM THE BODYS TISSUE AND BLOODBRANDS-HYDROCHROLOTHIAZIDECHLORTHALIDONE - [Centrally Acting Antihypertensives](https://www.elearning.dlife.in/lds-course-notes/centrally-acting-antihypertensives-10/) - Notes:CENTRAL ACTING AGENTS LOWER YOUR HEART RATE AND REDUCE BP THEY DO THID BY BLOCKING SIGNALS FROM YOUR BRAIN TO YOUR NERVOUS SYSTEM THAT SPEED UP YOUR HEART AND NARROW YOUR VEINS AND ARTERIESBRANDS-CLODINEMETHYLDOPAMOXONIDINE - [Calcium Channel Blockers or Calcium Antagonists](https://www.elearning.dlife.in/lds-course-notes/calcium-channel-blockers-or-calcium-antagonists-11/) - Notes:calcium channel blockers or channels or antagonists are a group of medication that disrupt the movement of calcium through calcium channels.these medications are used to decrease bpbrands-almodipinediltiazemverap - [Beta Blockers](https://www.elearning.dlife.in/lds-course-notes/beta-blockers-11/) - Notes:BETA BLOCKERS WORK BY BLOCKING THE EFFECTS OF THE HORMONE EPINEPHRINE ALSO KNOWN AS ADRENALINE.BETA-BLOCKERS CAUSE YOUR HEART TO BEAT MORE SLOWLY AND WITH LESS FORCE,WHICH LOWERS BP - [Angiotensin II Receptor Blockers](https://www.elearning.dlife.in/lds-course-notes/angiotensin-ii-receptor-blockers-10/) - Notes:ANGIOTENSIN 11 RECEPTORS BLOCKERS BLOCK THE ACTION OF ANGIOTENSIN 2BY PREVENTUNG ANGIOTENSIN 2 FROM BINDING TO ANGIOTENSIN 2 RECEPTORS ON THE MUSCLES SURROUNDING BLOOD VESSELS. AS A RESULT, BOOD VESSELS ENLARGE[DILATE] AND BP IS REDUCED BRAND- TELMISARTAN,TELMA,TELPRES,TELISTAVALSARTAN - [Other Popular Diets](https://www.elearning.dlife.in/lds-course-notes/other-popular-diets-9/) - Any diet is better than the Standard American diet, but does it really deliver results?DASH diet - acronym for Dietary Approaches to Stop Hypertension, promoted by the US-based National Heart, Lung, and Blood Institute to prevent and control hypertension (core focus), and is in no way a weight-loss diet. It is inspired from the observation - [Angiotensin Converting Enzyme Inhibitors](https://www.elearning.dlife.in/lds-course-notes/angiotensin-converting-enzyme-inhibitors-11/) - Notes:ANGIOTENSIN CONVERTING ENZYME INHIBITORS[ACE INHIBITORS]THEY WORK BY CAUSING RELAXATION OF BLOOD VESSELS AS WELL AS DECREASE IN BLOOD VOLUMEWHICH LEADS TO LOWER BLOOD PRESSURE AND DECREASED OXYGEN DEMAND FOR THE HEART - [Hypertension Medications](https://www.elearning.dlife.in/lds-course-notes/hypertension-medications-7/) - Notes:BP IS THE PRESSURE OF CIRCULATING BLOOD ON THE WALLS OF BLOOD VESSELS MOST OF THIS PRESSURE IS DUE TO THE WORK DONE BY THE HEART BY PUMPING BLOOD THROUGH THE CIRCULATORY SYSTEM - [Creatine](https://www.elearning.dlife.in/lds-course-notes/creatine-23/) - Creatine is a nitrogen-containing metabolite produced in the body from three amino acids: L-arginine, glycine, and L-methionine. It is primarily made in the liver and to a lesser extent in the kidneys and pancreas. Its phosphorylated form, phosphocreatine, donates phosphate groups to adenosine diphosphate (ADP), turning it back into ATP (ATP recycling, primarily in muscle - [Whey Protein](https://www.elearning.dlife.in/lds-course-notes/whey-protein-19/) - Whey is one the two proteins (other being casein) in milk. It is the liquid remaining after milk has been curdled and strained. It is a byproduct of the manufacture of paneer or cheese. Whey protein contains all 9 essential amino acids. Three primary types –Whey protein concentrate (WPC) – 25-89% protein content. Supplements in - [Heart Attack](https://www.elearning.dlife.in/lds-course-notes/heart-attack-13/) - Notes: - [GLP1 Analogues](https://www.elearning.dlife.in/lds-course-notes/glp1-analogues-11/) - Notes:GLP-1 ARE USED FOR THE TREATMENT OF TYPE 2 DIABETESTHEY WORK BY COPYING OR MIMICKING THE FUCTION OF THE NATURAL HORMONE INCRETIN IN YOUR BODY TAHT HELPS LOWER POST-,EAL BS LEVELS OZEMPIC COMES UNDER GLP-1 RECEPTOR CLASS OF MEDICINETHESE CLASS OF MEDICINE ALSO HELPS WITH T1DM AND ALSO OBESITYWEIGHT LOSS IS ANOTHER ADDED BIG BENEFIT OF - [Undenatured Collagen UC -II](https://www.elearning.dlife.in/lds-course-notes/undenatured-collagen-uc-ii-19/) - Collagen Type II is the primary structural protein in cartilage, making up the majority of its composition, especially hyaline cartilage (joint surfaces, nose, ears) and intervertebral discs, providing resistance to compression. Collagen type 2 contains chondroitin, hyaluronic acid, and the antioxidant proteoglycan which makes up the cartilage matrix glycoprotein. This crucial protein reduces oxidative stress - [Collagen](https://www.elearning.dlife.in/lds-course-notes/collagen-19/) - Collagen is the main structural protein in the extracellular matrix in the various connective tissues, and thereby the most abundant protein in mammals, comprising 25-35% of the whole-body protein content. It is one of the major building blocks of bones, skin, muscles, tendons, and ligaments. It is also found in many other body parts, including - [Silymarin / Milk Thistle](https://www.elearning.dlife.in/lds-course-notes/silymarin-milk-thistle-20/) - Silymarin is a flavonoid derived from a plant commonly known as milk thistle. It is arguably the most common used medication for various liver disease. Silibinin, also known as silybin, is the major active constituent of silymarin. Silibinin itself is a mixture of silybin A and silybin B.BenefitsThe silymarin extracted from milk thistle is known - [Resistant Starch](https://www.elearning.dlife.in/lds-course-notes/resistant-starch-19/) - Resistant starch is a carbohydrate that resists digestion in the small intestine and ferments in the large intestine, where it acts as a prebiotic and feeds the good bacteria in the gut. It functions similar to soluble, fermentable fiber, helping feed bacteria and increasing the synthesis of short-chain fatty acids (SCFAs) like butyrate. Resistant starch - [Omega 3 Fatty Acids](https://www.elearning.dlife.in/lds-course-notes/omega-3-fatty-acids-21/) - Omega-3 fatty acids are essential polyunsaturated fats that the body can't produce, requiring intake from foods. There are three main omega-3s: eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and alpha-linolenic acid, (ALA). EPA and DHA come mainly from fish, so they are sometimes called marine omega-3s. ALA comes mainly from plants (walnuts, flax seeds, leafy vegetables, - [N-Acetylcysteine](https://www.elearning.dlife.in/lds-course-notes/n-acetylcysteine-25/) - N-acetylcysteine (NAC) is an acetylated derivative and the supplement form of the amino acid L-cysteine (cysteine). The body needs folate, vit B6, and vit B12 to make cysteine. While the body can produce small amounts of cysteine and most protein-rich foods contain cysteine, some people take NAC supplements to increase their cysteine levels.BenefitsReplenishes the body's strongest - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-58/) - Notes: There were 4 main stages of human evolution.1. Between 4-7MYA. Consisted of the proto hominins. Sahelanthropus, Orrorin and ardipithecus. These may have been Bipedal.2. Around 4 MYA. Was marked by appearance of Australopithecus3. Around 2.7 MYA. Featured Paranthropus4. Existed betn 1.8-2.5 MYA.Features the genus Homo. Homo heidelbergensis appeared 800000 and Homo sapiens about 200000 - [Thiazolidinediones](https://www.elearning.dlife.in/lds-course-notes/thiazolidinediones-11/) - Notes:THIAZOLIDINEDIONES[GLITAZONES]TZDS DECREASE IR BY THE FORMATION OF NEW FAT CELLS MAINLY AROUND ARMS,THIGHS,AND BUTTS BRANDS- PIOGLITA - [Sodium-Glucose Cotransporter-2 – SGLT2 – Inhibitors](https://www.elearning.dlife.in/lds-course-notes/sodium-glucose-cotransporter-2-sglt2-inhibitors-11/) - Notes:SODIUM-GLUCOSE COTRANSPORTER-2 SGLT-2 ARE ANTI-DIABETIC DRUG AGENTS THAT ACT BY INHIBITING GLUCOSE REABSORPTION IN PROXIMAL CONOLUTES TUBLES OF THE KIDNEYBRANDS- DAPAGLIFLOZINCANAGLIFLOZINEMPAGLIFLOZIN - [Dipeptidyl peptidase-4 – DPP4 – Inhibitors](https://www.elearning.dlife.in/lds-course-notes/dipeptidyl-peptidase-4-dpp4-inhibitors-11/) - Notes:DPP-4 ARE A CLASS OF MEDICINE THAT LOWERS HBSLDPP-4 INHIBITORS SLOW THE INACTIVATION AND DEGRADATION OF GLP-1 A HORMONE INVOLVED IN GLUCOSE REMOVAL FROM THE GUTBRANDS-SITAGLIPTINSAXAGLIPTINLINAGLIPTINALOGLIPTIN - [MCT Oils](https://www.elearning.dlife.in/lds-course-notes/mct-oils-21/) - MCT oil is a dietary supplement made of Medium-Chain Triglycerides (MCTs), which are fats found in coconut oil, palm kernel oil, and dairy products. It is mainly used for weight loss or boosting workout endurance. Following are the main MCTs – caproic acid/hexanoic acid (C6), caprylic acid/octanoic acid (C8), capric acid/decanoic acid (C10), lauric acid/dodecanoic - [L Theanine](https://www.elearning.dlife.in/lds-course-notes/l-theanine-20/) - L-theanine - an amino acid found in tea leaves and some types of mushrooms, and is thought to be a source of umami, the savory, brothy taste.BenefitsReduces stress and anxiety.Increases focus.Improves immunity.Usage & Side EffectsGenerally, well tolerated by healthy adults.Following groups should consult a doctor before starting L-theanine supplements - pregnant/breastfeeding women, children, individuals with - [L Proline](https://www.elearning.dlife.in/lds-course-notes/l-proline-19/) - L-proline - a non-essential amino acid, proteinogenic, glucogenic.FunctionA major amino acid found in cartilage and is crucial for maintaining youthful skin, repair of muscle, connective tissue, and skin damage.An essential component of collagen and is crucial for the proper functioning of joints and tendons.Essential for the immune system.Helps maintain and strengthen heart muscles.DeficiencyProline deficiency is - [L Lysine](https://www.elearning.dlife.in/lds-course-notes/l-lysine-20/) - L-lysine - an essential amino acid, proteinogenic, exclusively ketogenic.Normal requirement - 8 g/day or 12 mg/kg/day in adults; 44 mg/kg/day for 11–12-year-old; 97 mg/kg/day for 3–6-month-old.Function - protein synthesis, providing structure to collagen, regulation of calcium levels, crucial in histone modification that affects gene expression.Low lysine levels have been found in patients with Parkinson's, hypothyroidism, - [Biguanides](https://www.elearning.dlife.in/lds-course-notes/biguanides-11/) - Notes:THE TERM BIGUANIDE REFERS TO A GRP OF DIABETES DRUGS THAT WORK BY PREVENTING THE PRODUCTION OF GLUCOSE IN THE LIVER IMPROVING THE BODYS SENSITIVITY TOWARDS INSULIN AND REDUCING THE AMOUT IF SUGAR ABSORBED BY THE INSTESTINES BRANDS - METFORMINRED BLOOD CELLS HELP TO TRANSPORT OXYGEN FROM OUR LNGS TO THE CELLS AND THEN THEY RELEASE - [Alpha Glucosidase Inhibitors](https://www.elearning.dlife.in/lds-course-notes/alpha-glucosidase-inhibitors-12/) - Notes:ALPHA-GLUCOSE INHIBITORS SLOWS DOWN THE DIGESTION OF CARBS BY BLOCKING THE ENZYME ALPHA-GLUCOSIDASE, WHICH HELPS IN DIGESTTING CARBS IN THE SLOW INTESTINE AND HELPS IN SLOWING THE ABSORPTION OF A CARBS RICH MEAL WHICH RESULTS IN LESS SPIKED OF BLOOD SUGAR AND HELPS WITH BETTER BLOOD SUGAR MANAGEMENTBRANDS- VOGLIBOSE - [L Leucine](https://www.elearning.dlife.in/lds-course-notes/l-leucine-21/) - Leucine is one of the nine essential amino acids in humans. It is a pyruvate family amino acid (can be synthesized from pyruvate in plants and microorganisms but not animals) and a proteinogenic amino acid. It is an α-amino acid and one of the three branched-chain amino acids (BCAA: leucine, isoleucine and valine, all 3 - [Fructose](https://www.elearning.dlife.in/lds-course-notes/fructose-12/) - Notes: - [Autophagy](https://www.elearning.dlife.in/lds-course-notes/autophagy-8/) - Notes:AUTOPHAGY IS THE BODYS NATURAL RECYCLING SYSTEM THAT CLEANS OUT DAMAGED CELLS AND REGENERTES NEW ONES, ESSENTIA FOR MAINTAINING HEALTH AND ADAPTING TO STRESS LIKE STARVATION - [Types of Intermittent Fasting](https://www.elearning.dlife.in/lds-course-notes/types-of-intermittent-fasting-10/) - Notes: 6 WAYS OF IF - THE 16/8 METHOD - FAST FOR 16HOURS EACH DAY . THIS CAN BE ACHIEVED BY SKIPPING EITHER DINNER BREAKFASTTHE 5:2 DIET - FATS FOR 2 DAYS A WEEK EAT-STOP-EAT- DO A 24 HOUR FAST ONCE OR TWICE A WEEKALTERNATE DAY FASTINGTHE WARRIOR DIET - FAST DURING THE DAY, EAT A HUGE MEAL - [Leptin](https://www.elearning.dlife.in/lds-course-notes/leptin-26/) - Notes: - [Leptin](https://www.elearning.dlife.in/lds-course-notes/leptin-27/) - Notes: - [The Role of Stress Management](https://www.elearning.dlife.in/lds-course-notes/the-role-of-stress-management-8/) - Notes:ASHWAGANDA IS SAID TO BE A GREAT STRESS BUSTER WHILE IMPROVING TH - [Leptin](https://www.elearning.dlife.in/lds-course-notes/leptin-23/) - Notes:leptin is a hormone that is released by your fat cells[adipose tissue] it helps in regulating body weight since leptin is produced by the fat cells the amount of leptin released and circulation is directly related to the amount of the body fatso the more fat an individual has the more leptin will be circulating in - [The Role of Sleep](https://www.elearning.dlife.in/lds-course-notes/the-role-of-sleep-10/) - Notes:YOUR BODY HAS AN INTERNAL BODY CLOCK THAT CONTROLS WHEN YOUR AWAKE AND WHEN YOUR BODY IS READY FOR SLEEPTHE BODY USUALLY HAS A 24 HOUR REPEATING RHYTHM CALLED THE CIRCADIAN RHYTHM A COMPOUND CALLED ADENOSINE TENDS TO RISE WHILE WE ARE AWAKE. THE INCREASING LEVEL OF THIS COMPOUND SIGNALS A SHIFT TOWARDS SLEEPWHEN IT GETS - [Strategies for Self-Promotion](https://www.elearning.dlife.in/lds-course-notes/strategies-for-self-promotion-8/) - Strategy for promotion - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-22/) - Notes:ectopic pregnancy (tubal) - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-59/) - Notes:Physical and behavioral traits shared by all people originated from apelike ancestors.Thses traits evolved a period of approx 6 million yearsone of the first Defining traits bipedalism. Evolved over 4 million years ago.Humans are primates.Modern human species Homo sapiensHomo sapiens and great apes have common ancestors lived between 6 to 8 million years ago.Human first - [Fructose](https://www.elearning.dlife.in/lds-course-notes/fructose-11/) - Notes:FRUCTOSE MAXIMUM ABSORPTION CAPACITY HAS BEEN SHOWN TO VARY BETWEEN 5- 50GMS, DEPENDING UPON AGE AND HEALTH CONIDTIONFRUCTOSE CONSUMPTION INCREASES THE RISK FOR HYPERTENSION,INCREASE ADIPOSITY, HYPERTRIGLYCERIDEMIA - [CoQ10](https://www.elearning.dlife.in/lds-course-notes/coq10-20/) - Notes:COENZYME 10COQ10 IS AN ANTIOXIDANT THAT YOUR BODY PRODUCES NATURALLY OUR CELLS USES COQ10 FOR GROWTH AND MAINTAINANCEANYONE TAKING STATIN[ A MEDICINE USED TO CONTROL CHOLESTROL AND REDUCE RISK OF CARDIOVASCULAR DISAEASE] SHOULD TAKE COQ10FOODS RICH IN COQ10-MEAT FISHCHICKENBEEFPORKVEGETABLE OILPARSLEYPERIILABROCCOLIGRAPESCAULIFLOWERCOQ10 CAN BE GIVEN FOR HEARTH HEALTH TRIGLYCERIDES MANAGEMENT - [TOFI – Thin Outside Fat Inside – Obesity](https://www.elearning.dlife.in/lds-course-notes/tofi-thin-outside-fat-inside-obesity-13/) - Notes:TOFI- THIN OUTSIDE FAT INSIDE IS USED TO DESCRIBE LEAN INDIVIDUALS WITH A DISPROPORTIONATE AMOUNT OF FAT STORED IN THIER ABDOMENTHE LOCATION OF FAT MATTERSSUBSCUTANEOUS FAT IS THE FAT STORED UNDER OUR SKINAND VISCERAL FATIS THE FAT STORED AROUND IN AND AROUND THE ABDOMEN THE AREA OF OUR ORGANS OR MUSCLESEVERY PERSONS FAT STORING CAPACITY - [Adipose Tissue](https://www.elearning.dlife.in/lds-course-notes/adipose-tissue-18/) - Notes: ADIPOSE TISSUE IS A LIPID STORING TYPE OF LOOSE CONNECTIVE TISSUE ALSO CALLED AS THE FAT TISSUEADIPOSE IS COMPOSED OF PRIMARILY OF ADIPOSE CELLS OR ADIPOCYTESIT CAN BE FOUND IN VARIOUS PLACES IN OUR BODY BUT IT IS PRIMARILY FOUND BENEATH THE SKINADIPOSE IS ALSO LOCATED BETWEEN MUSCLE AND AROUND INTERNAL ORGANS PARTICULARLY THOSE IN THE - [Current Treatment Options For NAFL and NASH](https://www.elearning.dlife.in/lds-course-notes/current-treatment-options-for-nafl-and-nash-10/) - Notes:SUPP TO HELP WITH NAFLD AND NASH -TURMERIC OR CURCUMINCOFFEEOMEGA 3 VIT E - [Liver Disease – Causes Symptoms Diagnosis & Prevention](https://www.elearning.dlife.in/lds-course-notes/liver-disease-causes-symptoms-diagnosis-prevention-10/) - Notes:YOUR LIVER IS AN IMP ORGAN THAT PERFORMS HUNDREDS OF TASKS RELATED TO METABOLISM,ENERGY STORGAE,AND DETOXIFICATION OF WASTEIT HELPS YOU DIGEST YOUR FOOD,CONVERT IT INTO ENERGY, AND STORE IT UNTIL YOU NEEDIT ALSO HELPS FILTER TOXIC SUBSTANCES OUT OF YOUR BLOODSTREAMSYMPTOMS OF LIVER DISEASE -SKIN OR EYE APPEARING YELLOW[JAUNDCE]ABDOMINAL PAIN AND SWELLINGSWELLING IN THE LEGS - [NAFLD – The Progression Details](https://www.elearning.dlife.in/lds-course-notes/nafld-the-progression-details-12/) - Notes:NAFL- NONALCOHOLIC FATTY LIVERNAFL IS CAUSED DUE TO THE ACCUMALATION OF FFA NAFL TYPICALLY DOES NOT PROGRESS TO CAUSE ANY DAMAGE, HOWEVER IT CAN BE PAINFUL DUE TO THE ENLARGEMENT OF THE LIVERNASH - NONALCOHOLLIC STEATOHEPATITIESNASH IS THE FORM OF NAFLD IN WHICH YOU HAVE INFLAMMATION OF THE LIVER AND LIVER DAMAGE, IN ADDITION TO FAT - [Quizzes and Assignments](https://www.elearning.dlife.in/lds-course-notes/quizzes-and-assignments-10/) - Notes:Quizzes are auto graded except specifically mentioned.Re attempting is allowed only one time.Assignment can not be re-taken once submitted. Marks awarded cannot be disputed. - [Notes Taking Explained](https://www.elearning.dlife.in/lds-course-notes/notes-taking-explained-28/) - Notes:Notes can be saved, edited and can be updated online.Notes can be downloaded anytime.Title of notes is pre-filled and non editableTimestamp can be seen on saved notesSaved notes can be viewed by clicking on the View all notes tabPrint out and download to Word format possible - [L Citrulline](https://www.elearning.dlife.in/lds-course-notes/l-citrulline-19/) - Citrulline is an α-amino acid produced in the body primarily through two main pathways. It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced as a byproduct of synthesis of NO from the amino acid arginine. Citrulline is also found in food and - [L-Carnitine](https://www.elearning.dlife.in/lds-course-notes/l-carnitine-19/) - Carnitine, derived from the essential amino acid lysine, is a generic term for a number of compounds. The body makes sufficient carnitine to meet the needs of most people (including strict vegetarians), and it is found in nearly all cells of the body. It transports long-chain FAs from the cytosol into mitochondria to be oxidized - [Non Alcoholic Fatty Liver Disease – NAFLD](https://www.elearning.dlife.in/lds-course-notes/non-alcoholic-fatty-liver-disease-nafld-12/) - Notes:THE LIVER IS A VITAL ORGAN OF THE BODY FOR OVERALL BODY HOMEOSTASIS THROUGH SEVERAL BIOCHEMICAL PROCESSES AND WITHOUT THESE FUNCTIONS LIFE CANNOT BE MAINTAINEDTHE HUMAN LIVER WEIGHS ABOUT 1.4KG AND IS FOUND IN THE RIGHT UPPER ABDOMEN, BELOW THE DIAPHGRAMTHE LIVER IS AN INCREDIBLY HARD-WORKING ORGAN WITH MORE THAN 500 DIFFERENT VITAL FUNCTIONSONLY YOUR - [PCOS & Obesity – The Connection](https://www.elearning.dlife.in/lds-course-notes/pcos-obesity-the-connection-11/) - Notes:SYMPTOMS OF PCOS WITH OBESITY-INFERTIITYTROUBLE LOSING WEIGHTOVARIAN CYSTSLOW SEX DRIVEIRREGULAR MENSESHIGH TESTOSTERONE LEVELSIRFATIGUE AND MOOD SWINGSINCREASE BODY HAIR GROWTHIN SUMMARY, WOMEN WITH PCOS ABDOMINAL OBESITY PLAY A KEY ROLE IN DETERMINING ADROGEN METABOLISM AND IRTHIS MAY BE OF IMPORTANCE IN PHENOTYPING PCOS AND IN DECIDING THE STRATEGY AIMED AT REDUCING IR AND HIGH ADROEGENS - [Inositol](https://www.elearning.dlife.in/lds-course-notes/inositol-19/) - Inositol, or more precisely myo-inositol, is a sugar alcohol with half the sweetness of sucrose (table sugar), made naturally in humans from glucose. A human kidney makes ~2 g/day and other tissues synthesize it too. It is found naturally in a variety of foods as well.It mediates cell signal transduction in response to a variety - [Glutamine](https://www.elearning.dlife.in/lds-course-notes/glutamine-18/) - Glutamine, also known as L-glutamine, is an α-amino acid and the most abundant amino acid in the blood and muscle cells. It is used in the synthesis of proteins and affects the processes of growth and function of cells in the stomach and intestines. It is classified as a conditionally essential amino acid. Dietary glutamine - [Glucosamine, Chondroitin, MSM, Hyaluronic Acid](https://www.elearning.dlife.in/lds-course-notes/glucosamine-chondroitin-msm-plus-hyaluronic-acid-16/) - Glucosamine is a natural chemical compound, an amino sugar and a prominent precursor to glycosylated proteins and lipids, in the body. It also comes as supplements in two main forms – hydrochloride and sulfate. These supplements are often made from natural sources like shellfish shells, animal bones, and fungi.Chondroitin is a vital component of cartilage. - [Gelatin](https://www.elearning.dlife.in/lds-course-notes/gelatin-17/) - Gelatin is 98-99% protein, derived from partial hydrolysis of collagen, the most abundant protein in humans and animals. Gelatin is found in animal parts that provide us with a unique amino acid profile bringing many of its health benefits – Glycine 27%, Proline 16%, Valine 14%, Hydroxyproline 14%, Glutamic acid 11%.Gelatin can be processed further - [Flaxseed Oil](https://www.elearning.dlife.in/lds-course-notes/flaxseed-oil-16/) - Flaxseed oil, also known as linseed oil, is extracted from ripened flaxseeds. It contains plant-based omega-3, α-linolenic acid, which is also found abundantly in walnuts. But flaxseed oil is by far the richest source with ~7 g α-linolenic acid per tbsp.α-linolenic acid has is required to be converted into eicosapentaenoic acid (EPA) and docosahexaenoic acid - [Exogenous Ketones](https://www.elearning.dlife.in/lds-course-notes/exogenous-ketones-17/) - The ketogenic diet (high fat, very low carbs) aims for nutritional ketosis 24×7, in which the body burns fat instead of carb as its primary fuel. The two main ketone bodies produced during ketosis are acetoacetate and beta-hydroxybutyrate, and acetone is the less abundant, third ketone body.Exogenous ketones are supplements that could help achieve ketosis - [Egg Shell Membrane](https://www.elearning.dlife.in/lds-course-notes/egg-shell-membrane-21/) - Eggshell consists of ~40% calcium (in calcium carbonate form) and the rest protein and other minerals. Each gram provides 381-401 mg calcium.BenefitsHas anti-inflammatory and wound healing properties.Eggshell powder improves health of bone and cartilage and is suitable for prevention/treatment of osteoporosis.Supplements made of eggshell membranes may improve joint health.Eggshell powder is an effective source of - [Curcumin / Turmeric](https://www.elearning.dlife.in/lds-course-notes/curcumin-turmeric-19/) - Turmeric is a whole spice that provides a broad spectrum of natural compounds that work together for general wellness and culinary uses. It is the major source of the polyphenol curcumin that can be taken as a concentrated supplement to address health concerns such as joint pain and heart health.BenefitsCurcumin supplements may reduce inflammation.Curcumin and - [dLife Case Story – Atrial Fibrillation (AFib) & Hypertension](https://www.elearning.dlife.in/lds-course-notes/dlife-case-story-atrial-fibrillation-afib-hypertension-2/) - Notes:ATRIAL FIBRILLATION- IS THE MOST COMMON IRREGULAR HEART RHYTHM [ARRHYTHMIA ] WHERE THE HEARTS UPPER CHAMBER CAUSES IRREGULAR OR FAST HEART BEAT - [CoQ10](https://www.elearning.dlife.in/lds-course-notes/coq10-22/) - Coenzyme Q10 (CoQ10) is an antioxidant that is naturally produced in the body and cells use it for growth and maintenance. It is the most common form, also known as ubiquinone-10, of the ubiquinone/Coenzyme Q (CoQ) family, found ubiquitously in cells. CoQ10 exists in both oxidized (ubiquinone) and reduced (ubiquinol) forms, and continual conversion between - [Cinnamon](https://www.elearning.dlife.in/lds-course-notes/cinnamon-19/) - Cinnamon is a spice obtained from the inner bark of several tree species from the genus Cinnamomum.Cinnamon supplements mainly come in two types: common, cheaper Cassia (high in liver-toxic coumarin) and milder, safer Ceylon ("true" cinnamon) with very low coumarin, making Ceylon best for regular, high-dose use to avoid liver issues. Both offer benefits like - [Casein](https://www.elearning.dlife.in/lds-course-notes/casein-20/) - Casein is a family of related phosphoproteins, commonly found in mammalian milk. It forms ~80% of the bovine milk proteins. Casein provides amino acids, carbohydrates, calcium, and phosphorus. It is the major anti-catabolic protein preventing muscle protein breakdown. Two main forms - Micellar casein (most popular, digested slowly) and casein hydrolysate (predigested, rapidly absorbed).Micellar casein - [Heart Failure](https://www.elearning.dlife.in/lds-course-notes/heart-failure-10/) - Notes:HEART FAILURE OCCURS WHEN THE HEART IS UNABLE TO PUMP BLOOD AS WELL AS IT SHOULD - [Heart Attack](https://www.elearning.dlife.in/lds-course-notes/heart-attack-12/) - Notes:HEART ATTACK OCCURS WHEN THERE IS A SUDDEN LOSS OF BLOOD SUPPLY TO THE HEARTWHILE HEART FAILURE IS WHEN THE HEART IS UNABLE TO PUMP BLOOD EFFICIENTLYCARDIAC ARREST- CA IS A SUDDEN STOPPING OF THE HEART DUE TO ARRTHYMIA WHICH CAUSES THE HEART TO STOP PUMPING BLOOD - [β-Alanine](https://www.elearning.dlife.in/lds-course-notes/β-alanine-20/) - β-Alanine is a naturally occurring beta amino acid, which is a modified version of the amino acid alanine and is a non-essential amino acid. Unlike most amino acids, it is not used by the body to synthesize proteins.BenefitsAmino acids β-alanine and histidine are the building blocks of carnosine, which is naturally produced in the liver - [Berberine](https://www.elearning.dlife.in/lds-course-notes/berberine-20/) - Berberine is a bitter, yellow chemical compound from plants like barberry, goldenseal, and Oregon grape, usually found in the roots, rhizomes, stems, and bark.BenefitsActivates enzyme AMP-activated protein kinase (AMPK), sometimes referred as “metabolic master switch”. AMPK is found in the cells of various organs, including the brain, muscle, kidney, heart, and liver, and plays a - [BCAA](https://www.elearning.dlife.in/lds-course-notes/bcaa-23/) - BCAA or Branched Chain Amino Acids includes 3 essential amino acids – Leucine, Isoleucine and Valine. BCAA comprise ~35% of the body’s muscle protein.Leucine – stimulates Growth hormone (HGH) release that greatly stimulates muscle growth. Also, stimulates insulin release and greatly boosts protein synthesis and inhibits muscle breakdown. It is the ketogenic amino acid (its - [Astaxanthin](https://www.elearning.dlife.in/lds-course-notes/astaxanthin-22/) - Astaxanthin is a naturally occurring carotenoid found in algae, shrimp, lobster, crab, salmon, rainbow trout, and other seafood. It is a powerful antioxidant and one of the best ways to ingest antioxidant. Carotenoids are naturally occurring pigment colours that support good health. β-carotene is orange and belongs to the subclass of xanthophyll, which are oxygen-containing - [Cardiovascular Disease – CVD](https://www.elearning.dlife.in/lds-course-notes/cardiovascular-disease-cvd-14/) - Notes:CAD- CORONARY ARTERY DISEASECAD IS CAUSED BY ATHEROSCLEROSIS IN THE COONARY ARTERY. THIS HAPPENS DUE TO THE BUILD UP OF PLAQUECHF - CONGESTIVE HEART FAILURECHF IS A SERIOUS AND LONG TERM CONDITION THAT GETS WORST WITH TIMETHE HEART CAN NO LONGER WORK WELL AS IT SHOULD, SO TO MAKE UP FOR THIS THE HEART MAY - [Cardiomyopathy](https://www.elearning.dlife.in/lds-course-notes/cardiomyopathy-12/) - Notes:CARDIOMYOPATHY REFERS TO THE DISEASE OF THE HEART MUSCLEIN MOST CASES CMP MAKES THE HEART MUSCLE BECOME ENLARGED,THICK OR RIGIDAS CMP WORSENS THE HEART BECAMES WEAK AND RESULTS INTO HEART FAILURE. THE WEAKENED HEART ALSO CAUSES VARIOUS OTHER PROBLEMS SUCH AS HEART VALVE PROBLEMCMP CAN ALSO BE CAUSED DUE TO OTHER DISEASE SUCH AS IR,DIABETES,HIGH - [Ashwagandha](https://www.elearning.dlife.in/lds-course-notes/ashwagandha-21/) - Ashwagandha is an herb used in Ayurveda. Extracts of its roots are more commonly used in supplements than other parts of the plant. Its root has a horsey smell (ashva means horse and gandha means smell in Sanskrit) and is said to confer the strength and virility of a horse.BenefitsReduces stress and anxiety.As per one - [Alpha Lipoic Acid](https://www.elearning.dlife.in/lds-course-notes/alpha-lipoic-acid-25/) - Alpha Lipoic Acid (ALA), also known as lipoic acid and thioctic acid, is an organosulfur compound containing two sulfur atoms. C8H14O2S2. It is a naturally occurring fatty acid found in many foods. It is also available as supplement/drug. It is both water- and fat-soluble allowing it to work in every cell/tissue in the body.FunctionCofactor for - [Supplements](https://www.elearning.dlife.in/lds-course-notes/supplements-11/) - Supplements include vitamins, minerals, amino acids, fatty acids, and other required substances delivered in the form of pills, tablets, capsules, liquid, etc.Need examplesOsteoporosis patients may require extra vit D and calcium beyond what they get from diet.Supplements help in conditions which hamper absorption of nutrients, such as Crohn's disease or celiac disease.Supplement is almost necessary - [Iodine](https://www.elearning.dlife.in/lds-course-notes/iodine-20/) - Function – The only biological role of iodine is in the formation of thyroid hormones. It is an essential component of thyroxine (T4) and triiodothyronine (T3), which regulate many biochemical reactions, including protein synthesis and enzymatic activity, and are critical for metabolic activity and skeletal/CNS development in fetuses and infants. TSH is the primary regulator of thyroid - [Manganese](https://www.elearning.dlife.in/lds-course-notes/manganese-19/) - FunctionCofactor for many enzymes including manganese superoxide dismutase, arginase, isocitrate dehydrogenase, cholinesterase, pyruvate carboxylase, and all hydrolases and decarboxylases, thereby involved in following important functions – metabolism of amino acid, cholesterol, glucose, and carbohydrate; reactive oxygen species scavenging; anti-inflammatory response as part of the powerful antioxidant superoxide dismutase; bone formation; reproduction; immune response. Manganese and - [Chromium](https://www.elearning.dlife.in/lds-course-notes/chromium-20/) - Chromium is a trace mineral needed in very small amounts. Its mechanism of action in the body and the amounts needed for optimal health are not well defined. It is found primarily in two forms - trivalent (chromium 3+) - biologically active and found in foodhexavalent (chromium 6+) - a toxicant from industrial pollutionFunctionPromotes insulin's action, - [Molybdenum](https://www.elearning.dlife.in/lds-course-notes/molybdenum-18/) - Molybdenum is a trace mineral essential to health. Its content in foods depends on the content of the soil.FunctionPrevents build-up of deadly sulfites and toxins.Essential component of molybdopterin, a cofactor required for four enzymes – sulfite/xanthine/aldehyde oxidase and Mitochondrial amidoxime reducing component. Molybdopterin carries Mo to the catalytic site of the apoenzyme where it undergoes - [Insulin Resistance & Diabetes](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-diabetes-30/) - Notes:LADAFBS 901 hr PPBS 1402 hr PPBS 120A1C 5.6Fasting insulin - [Insulin Resistance & Obesity](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-obesity-30/) - Notes:Bookmark to revisit.Lots of historical perspective. - [Selenium](https://www.elearning.dlife.in/lds-course-notes/selenium-18/) - FunctionImportant for many bodily functions - cognition, healthy immune system, fertility in men/women.Constituent of more than two dozen selenoproteins that play critical role in reproduction, thyroid hormone metabolism, DNA synthesis, and protection from oxidative damage and infection.As a prosthetic of glutathione peroxidase, selenium acts as a non-specific antioxidant in detoxification reactions, which has special significance - [Atherosclerosis](https://www.elearning.dlife.in/lds-course-notes/atherosclerosis-13/) - Notes:ATHEROSCLEROSIS IS THE BUILDUP OF POLAQUE IN THE ARTERIESPLAQUE – A PLAQUE FORMS IN THE INNER LAYER OF THE ARTERIES PLAQUE IS A BUILDUP OF CHOLESTEROL, WHITE BLOOD CELLS,CALCIUM AND OTHER SUBSTANCES IN THE WALLS OF THE ARTERIESOVERTIME, THE PLAQUE NARROWS THE ARTERY AND THE ARTERY HARDENSIN CORONARY ARTERY DISEASE- COMPLETE BLOCKAGE OF THE ARTERY HAPPENS - [Iron](https://www.elearning.dlife.in/lds-course-notes/iron-20/) - Iron is a crucial mineral. Dietary iron exists in heme and nonheme forms. Plants and iron-fortified foods contain nonheme iron only, whereas animal-based foods contain both.FunctionEssential component of hemoglobin, an erythrocyte protein in RBCs that transfers oxygen from the lungs to all cells and tissues of the body.As a component myoglobin, another protein that provides - [Zinc](https://www.elearning.dlife.in/lds-course-notes/zinc-23/) - Zinc is an essential trace metal ion that is ubiquitous in many metabolic and physiological processes.FunctionCofactor for 100-300 enzymes in metabolism, digestion, nerve function, etc.Crucial role in immune function, protein synthesis, wound healing, and cell division.Integral part of several metalloenzymes like superoxide dismutase, carbonic anhydrase, leucine aminopeptidase.Stimulates the release of vit A from the liver - [Copper](https://www.elearning.dlife.in/lds-course-notes/copper-22/) - Copper is an essential trace mineral crucial for many fundamental bodily functions.FunctionPrimarily functions as a component of metalloenzymes that participate in redox reactions.Cofactor for several enzymes (called cuproenzymes, at least 12 in number) involved in energy production, neuropeptide activation, synthesis of connective tissues and neurotransmitters, and iron metabolism.Part of several enzymes and proteins that are - [LCHF Diet](https://www.elearning.dlife.in/lds-course-notes/lchf-diet-21/) - Notes:Carbs - 20% of total cal intake OR 100 gm - whichever is lower. Protein - 20% of total cal intake or 100 gm - whichever is higher. Carbs + Protein should be 40% of the total diet cals. If Protein is incr then Carbs will have to be decr - to keep total at 40%.For eg, - [Folate](https://www.elearning.dlife.in/lds-course-notes/folate-22/) - Notes: - [Minerals](https://www.elearning.dlife.in/lds-course-notes/minerals-14/) - Essential minerals are divided into two groups based on the amounts needed – macrominerals (major minerals) are needed in larger amounts than microminerals (trace minerals) – however, the amounts needed are not an indication of their importance. All the essential minerals must be obtained from foods or supplements, as the human body doesn't manufacture them - [Sulfur](https://www.elearning.dlife.in/lds-course-notes/sulfur-22/) - Sulfur, after calcium and phosphorus, is the most abundant mineral element found in our body. We derive sulfur almost exclusively from proteins, and only 2 of the 20 amino acids contain sulfur - methionine (essential) and cysteine (non-essential). Methionine cannot be synthesized by our bodies. Cysteine is synthesized by us, but the process requires a - [Phosphorus](https://www.elearning.dlife.in/lds-course-notes/phosphorus-21/) - Phosphorus is the second most plentiful mineral in the body after calcium. Bone is the principal reservoir of phosphorus in the body.FunctionBuilds strong bones and teeth.Manages how body stores and uses energy.Assists in muscle contractions. Reduce muscle pain after exercise.Filters out waste in kidneys.Grows, maintains, and repairs tissue and cells. Critical in essential cellular functions.Produces - [Calcium](https://www.elearning.dlife.in/lds-course-notes/calcium-23/) - Calcium is an essential mineral. The body doesn’t produce it, so one needs to absorb it from food, which also requires vit D. It is found in good amounts in dairy products. Chemically it’s an alkaline earth metal. ~99% stored in bones and teeth, and only 1% needed for other critical functions. Serum calcium is - [Exogenous Insulin](https://www.elearning.dlife.in/lds-course-notes/exogenous-insulin-10/) - [Introduction To Anthropometry](https://www.elearning.dlife.in/lds-course-notes/introduction-to-anthropometry-25/) - Notes:waist to hip ratio:women: - [Glucagon](https://www.elearning.dlife.in/lds-course-notes/glucagon-32/) - Notes: glucagon glycogen glucose - [Vitamin B6](https://www.elearning.dlife.in/lds-course-notes/vitamin-b6-22/) - Vitamin B6 is a water-soluble vitamin and refers to a group of six chemically similar compounds, i.e., “vitamers”, which can be interconverted in biological systems. These are pyridoxine (an alcohol), pyridoxal (an aldehyde), pyridoxamine (contains an amino group), and their respective phosphorylated derivatives pyridoxine 5′-phosphate, pyridoxal 5′-phosphate (PLP) and pyridoxamine 5′-phosphate (PMP). PLP has the - [Thiamine (B1)](https://www.elearning.dlife.in/lds-course-notes/thiamine-22/) - Thiamine is a water-soluble vitamin, also known as thiamin, vitamin B1, anti-beriberi vit, and antineuritic vit. Dietary thiamin is in phosphorylated (ester) form in animal foods and free form in plant foods. Thiamine diphosphate (TDP), also known as thiamine pyrophosphate (TPP), is the main metabolically active form and the primary thiamine-containing compound in the body. - [Gestational Diabetes](https://www.elearning.dlife.in/lds-course-notes/gestational-diabetes-12/) - Notes:GESTATIONAL DIABETES- DIABETES DEVELOPED DURING PREGNANCYDURING PREGNANCY YOUR BODY MAKES SPECIAL HORMONE AND GOES THROUGH OTHER CHANGES SUCH AS WEIGHT GAINBCUZ OF THESE CHANGES YOUR BOYS CELL DONT USE INSULIN WELL A CONDITION CALLED IRALL PREGNANT WOMEN HAVE SOME IR DURING LATE PREGNANCY MOST PREGN WOMEN CAN PRODUCE ENOUGH INSULIN TO OVERCOME IR BUT SOME CANNOTTHESE - [Type 1 Diabetes](https://www.elearning.dlife.in/lds-course-notes/type-1-diabetes-14/) - Notes:JUVENILE OR TYPE 1 DIABETES-TYPE 1 DIABETES INM CHILDREN IS A CONDITION WHERE THIER BODY NO LONGER PRODUCES INSULIN.INSULIN IS NEEDED FOR SURVIVAL SO IT IS REPLACED WITH INJECTIONSTYOE 1 WHICH HAPPENS IN CHILDREN IS ALSO KNOWN AS JUVENILE DIABETESIT CANNOT BE CURED, BUT CAN BE MANAGEDLADA[LATENT AUTOIMMUNE DIABETES IN ADULT] OR TYPE 1.5 DIABETES-LADA - [Niacin (B3)](https://www.elearning.dlife.in/lds-course-notes/niacin-b3/) - Vitamin B3, colloquially referred to as niacin, is a water-soluble vitamin that includes three vitamers: nicotinic acid (niacin, pyridine-3-carboxylic acid), nicotinamide (niacinamide, pyridine-3-carboxamide), and nicotinamide riboside. All three vitamers are converted within the body to the main metabolically active coenzyme, nicotinamide adenine dinucleotide (NAD), which is also converted to another active coenzyme, nicotinamide adenine dinucleotide - [Diabetes](https://www.elearning.dlife.in/lds-course-notes/diabetes-15/) - Notes:INSULIN- HELPS LOWER BGLGLUCAGON- HELPS RISE BGLSOMATOSTATIN- ACTS AS A PANCREATIC POLICEMAN BALANCING INSULIN AND GLUCAGON. IT HELPS THE PANCREAS IN TURNING OR TURNING OFF EACH OPP HORMONEAMYLIN- SATIETY HORMONEINCRETINS- ARE GLUCAGON LIKE PEPTIDE HORMONES MADE IN CELL OF THE SMALL INTESTINE AND IS SECRETED INTO THE CIRCULATION IN RESONSE WITH FOOD INTAKETHEY ALSO SLOW - [Vitamin B12 (Cobalamin)](https://www.elearning.dlife.in/lds-course-notes/vitamin-b12-25/) - Vitamin B12, also known as cobalamin or extrinsic factor, is the most chemically complex of all vitamins, and is synthesized exclusively by certain archaea and bacteria. Vitamin B12 vitamers are the different forms of the vitamin, which all contain a central cobalt ion within a corrin ring. Four common forms -Adenosylcobalamin - naturally occurring form - [Vitamin C](https://www.elearning.dlife.in/lds-course-notes/vitamin-c-24/) - Vitamin C is an essential, water-soluble nutrient, also known as L-ascorbic acid or simply ascorbic acid. It is obtained primarily from fruits and vegetables like citrus fruits, strawberries, peppers, leafy greens, and broccoli. Vit C is highly bioavailable. It is a powerful antioxidant and also a cofactor for a family of biosynthetic and regulatory enzymes - [Aldosterone](https://www.elearning.dlife.in/lds-course-notes/aldosterone-19/) - Notes:high aldosterone causes sodium deregulation, increasing sodium reabsorption and blood pressure. - [Adiponectin](https://www.elearning.dlife.in/lds-course-notes/adiponectin-31/) - Notes: turmeric + pepper, chili pepper (capsaicin) and ginger combined increase adiponectin, critical for adiponectin. - [Obesity & Hypertension](https://www.elearning.dlife.in/lds-course-notes/obesity-hypertension-11/) - Notes:CHANGES IN BLOOD PRESSURE ARE MADE IN ORDER TO DIRECT APPROPRIATE AMOUNTS OF OXYGEN AND NUTRIENTS TO SPECIFIC PARTS OF THE BODYFOR EXAMPLE WHEN EXCERSING MUSCLE REQUIRE MORE OXYGEN SO THE BLOOD DILEVERY TO THE DIGESTIVE ORGAN DECREASES ADJUSTMENTS IN BLOOD PRESSURE ARE ALSO REQUIRED WHEN FOCUS ARE APPLIED TO YOUR BODY IF A PERSON IS OBESE - [Vitamin E](https://www.elearning.dlife.in/lds-course-notes/vitamin-e-22/) - Vitamin E is a group of eight fat-soluble compounds related in molecular structure that includes four tocopherols and four tocotrienols, both occur in α, β, γ, and δ (delta) forms. These eight vitamers have varying levels of biological activity and feature a hydroxyl group that can donate a hydrogen atom to reduce free radicals, but - [Vitamin K](https://www.elearning.dlife.in/lds-course-notes/vitamin-k-23/) - Vitamin K refers to structurally similar, fat-soluble vitamers, and includes several chemical compounds, which are similar in structure. It includes two natural vitamers – plant-sourced foods are primarily vit K1 (phylloquinone) and animal-sourced foods are primarily vit K2 (menaquinone) – both are naphthoquinone derivatives. Vit K2, in turn, consists of a number of related chemical - [Vitamin D](https://www.elearning.dlife.in/lds-course-notes/vitamin-d-22/) - Vitamin D refers to a group of fat-soluble prohormones. Vit D itself has little biological activity and is a precursor that the body must activate to create the actual hormone that carries out its functions. In humans, important compounds in this group are vit D3 (cholecalciferol) and vit D2 (ergocalciferol).You can get vit D from - [Vitamin A](https://www.elearning.dlife.in/lds-course-notes/vitamin-a-22/) - Vitamin A is a group of fat-soluble compounds, retinol being the most usable one. Two main types:Preformed vitamin A (retinoids) – active form of vit A that the body can use directly, found in animal products like liver, eggs, fish, and dairy. Retinoids include retinol (vit A alcohol), retinal/retinaldehyde (vit A aldehyde), retinoic acid (vit - [Obesity Is A Metabolic Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-is-a-metabolic-disorder-16/) - Notes:OBESITY IS AN ENLARGMENT OF ADIPOSE TISSUE TO STORE EXCESS ENERGY INTAKETO HANDLE EXCESS ENERGY ADIPOSE TISSUE EXPANDS BY INCREASING ADIPOCYTE SIZEADIPOSE TISSUE CAN GROW BY TWO MECHANISMS-HYPERLASIA [CELL NUMBER INCREASE]HYPERTROPHY [ CELL SIZE INCREASE]INSULIN IS THE HORMONE THAT DICTATES THE BODY WHAT TO DO WITH THE ENERGY EITHER TO USE IT OR STORE ITOBESITY - [Insulin Resistance, Lipotoxicity & Energy Toxicity](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-lipotoxicity-energy-toxicity-8/) - Notes:ENERGY TOXICITY- IS A METABOLLIC STATE CHARACTERIZED BY THE ACCUMALATION OF EXCESS ENERGY, PRIMARILY STORED AS TRIGLYCERIDES IN MUSCLE AND LIVER CELLSLIPOTOXICITY- REFERS TO THE HARMFUL EFFECTS OF EXCESS TISSUE FAT ACCUMALATION ON GLUCOSE METABOLISM SO EXCESS GLUCOSE CAN BE CONVERTED INTO FAT ONCE GLYCOGEN STORES ARE FULL LIPOTOXICITY IS CAUSED BY STORAGE OF FAT IN ARES - [The Role Of Nutrition In Human Health](https://www.elearning.dlife.in/lds-course-notes/the-role-of-nutrition-in-human-health-22/) - Notes: - [The Origin Of Carbohydrate Restriction In Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-origin-of-carbohydrate-restriction-in-chronic-diseases-13/) - Notes:Surg Gen John Rollo – Notes of a Diabetic Case (treated an Offr with Diabetes using LCHF diet consisting of meat, rancid fat, blood pudding, milk & lime water, with minimal bread & excl most plant foods & sugars.Rebecca Oppenheimer – Cookbook for Diabetics (1854) recom meat, fish, cheese, olive oil & eggs.William Banting – - [Myth: Dietary Fat Causes Weight Gain](https://www.elearning.dlife.in/lds-course-notes/myth-dietary-fat-causes-weight-gain-21/) - Notes:Oral ingestion of 100 gm glucose spikes insulin more than IV inj of 100 gm glucose due to the 'incretin effect', where gut hormones like Glucose-dependent insulinotropic polypeptide (GIP) & Glucagon-like peptide-1 (GLP-1) which enhance insulin secretion beyond what glucose levels alone produce during IV delivery. Leptin Resistance:-High leptin lvls from fat cells fail to suppress - [Introduction To Anthropometry](https://www.elearning.dlife.in/lds-course-notes/introduction-to-anthropometry-24/) - Notes:alphonse bertillon, french policeman, invented anthropometrics. - [Fats](https://www.elearning.dlife.in/lds-course-notes/fats-27/) - Notes: conjugated Linoleic acid which is found in dairy fat is good - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-32/) - Notes:lactase and pepsin are main enzyme - [Norepinephrine](https://www.elearning.dlife.in/lds-course-notes/norepinephrine-18/) - Notes:norepinephrine also called as noradrenaline is produced in the inner part of the adrenal gland it plays a vital role in regulating your mood and ability to concentrate and together with other hormones norepinephrine helps the body to respond to stress and exerciseother hormones include-adrenalinecortisolnore along with adrenaline increases heart rate and blood pumping rateit increases - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-62/) - Notes:Rice first grown in SE Asia - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-58/) - Notes:Meat incorporation in diet occurred 2.6 million yrs ago. - [Folate](https://www.elearning.dlife.in/lds-course-notes/folate-21/) - Notes: - [Folate (B9)](https://www.elearning.dlife.in/lds-course-notes/folate-b9/) - Folate, also known as vitamin B9 or folacin, is a water-soluble vitamin. Unlike many other vitamins, which have several vitamers, folate is only one chemical compound, C19H19N7O6. Manufactured folic acid, which is converted into folate by the body, is used as a dietary supplement and in food fortification as it is more stable during processing - [Foods: The ‘Yes’, ‘May’ & ‘Never’ List](https://www.elearning.dlife.in/lds-course-notes/foods-the-yes-may-never-list-25/) - Notes: - [Biotin (B7)](https://www.elearning.dlife.in/lds-course-notes/biotin-b7/) - Biotin, also known as vitamin B7 or vitamin H, is a water-soluble vitamin. Unlike many other vitamins, which have several vitamers, biotin is only one chemical compound, C10H16N2O3S.FunctionCoenzyme for five carboxylase enzymes - carboxylases catalyze carboxylation, a chemical reaction in which a carboxylic acid is produced by treating a substrate with carbon dioxide.Acetyl-CoA carboxylase 1 - - [Pantothenic Acid (B5)](https://www.elearning.dlife.in/lds-course-notes/pantothenic-acid-b5/) - Pantothenic acid, also known as pantothenate or vitamin B5, is a water-soluble vitamin. Its name comes from the Greek pantothen, meaning “from everywhere”, because pantothenic acid, at least in small amounts, is in almost all foods. Unlike many other vitamins, which have several vitamers, pantothenic acid is only one chemical compound (C9H17NO5). All of pantothenic - [Riboflavin (B2)](https://www.elearning.dlife.in/lds-course-notes/riboflavin-b2/) - Riboflavin, also known as vitamin B2, is a water-soluble vitamin. Unlike many other vitamins, which occur in several chemically related forms known as vitamers, riboflavin is only one chemical compound (C17H20N4O6). All of riboflavin's biological roles seems to be dependent on its phosphorylated derivatives, which act as coenzymes for hundreds of enzymes and many metabolic - [Myth: PUFA Loaded Vegetable Oils Are Better Than Saturated Fat](https://www.elearning.dlife.in/lds-course-notes/myth-pufa-loaded-vegetable-oils-are-better-than-saturated-fat-56/) - Notes: mitochondria disfunction and DNA damage is metabolic syndrome - [LIPID Peroxidation & Cardiovascular Disease (CVD)](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-cardiovascular-disease-cvd-12/) - Notes: - [Myth: Saturated Fat Causes Heart Disease](https://www.elearning.dlife.in/lds-course-notes/myth-saturated-fat-causes-heart-disease-33/) - Notes: linoleic Acid from poly unsaturated fat - [Myth: PUFA Loaded Vegetable Oils Are Better Than Saturated Fat](https://www.elearning.dlife.in/lds-course-notes/myth-pufa-loaded-vegetable-oils-are-better-than-saturated-fat-55/) - Notes:food changes DNA - example Oxlams - [Myth: Carbohydrates Are Essential - BRAIN - IN absence of sugar ketone bdies generated by liver partly eplace glucose as a fuel for the brain](https://www.elearning.dlife.in/lds-course-notes/myth-carbohydrates-are-essential-brain/) - Notes: - [Cholesterol & Its Functions](https://www.elearning.dlife.in/lds-course-notes/cholesterol-its-functions-17/) - Notes:CHOLESTEROL IS AN ORGANIC COMPOUND THAT THE BODY REQUIRES FOR CELL MEMBRANE AND FOR HORMONES LIKE ESTROGEN AND TESTOSTERONEMOST OF THE WAXY SUBSTANCE IS MADE BY THE LIVER AND THE REST COMES FROM DIETARY SOURCES LIKE MEAT EGGS FISH AND DAIRY PRODUCTSCHOLESTEROL CONTENT IN THE BLOODSTREAM IS REGULATED BY THE LIVERMOST INGESTED CHOLESTEROL IS ESTERIFIED - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-21/) - Digestion – Catalyzes breaking down (hydrolysis) of TG into free fatty acids and glycerol, critical for energy and cell membrane synthesis. Possesses an alpha/beta-hydrolase fold with a central β-sheet and an alpha-helical lid covering a catalytic triad – serine (neuclophile), histidine (base), aspartate/glutamate (acidic residue) – within a hydrophobic pocket. Metabolism – Plays role in lipid - [LIPID Peroxidation & Cardiovascular Disease (CVD)](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-cardiovascular-disease-cvd-11/) - Notes:LPO IS A BIOCHEMICAL PROCESS INVOLVING THE OXIDATIVE DEGRADATION OF LIPIDS LEADING TO THE FORMATION OF REACTIVE OXYGEN SPECIES AND VARIOUS BYPRODUCTS THAT CAN SIGNIFICANTLY IMPACT CAEDIOVASCULAR HEALTHATHEROSCLEROSIS IS CHARACTERIZED BY THE ACCUMULATION OF OXIDIZED LDL WITHIN THE ARTERIAL WALLSIT IS BASICALLY THE DEGRADATION OF OILS AND PUFA S WHICH AFTER THE OXIDATION IN OUR - [LIPID Peroxidation](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-12/) - Notes:LIPID PEROXIDATION IS A COMPLEX BIOCHEMICAL PROCESS THAT LEADS TO THE OXIDATIVE DEGRADATION OF LIPIDS PARTICULARLY POLYUNSATURATED FATTY ACIDSEXCESS COMSUMPTION OF PUFAS CAN LEAD TO INCREASED LEVEL OF LIPID PEROXIDATION IN THE BODY CONTRIBUTING TO VARIOUS HEALTH PROBLEMSFREE RADICALS INITIATE THE LIPID PEROXIDATION PROCESS IN AN ORGANISMIRON IS VITAL FOR TUMOR CELL GROWTH ITS EXCESS - [Vitamins](https://www.elearning.dlife.in/lds-course-notes/vitamins-24/) - RolesBoosts immune system.Supports normal growth and development.Helps cells and organs to function properly – plays fundamental role in cellular energy generation or metabolism – can act as coenzyme and cofactors in numerous metabolic processes and are also the active proton and electron carriers in the ATP-generating cellular respiratory chain.Quick FactsThere are 13 known vitamins.An essential - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-57/) - Notes: first (4-7 MYA) proto hominis,sahelanthropus,orrorin,ardipithecus.second- australopithecus .third-paranthropusfourth- homohabilis, homo erectus, homoergastor, homo heidelbergensis,homosapiens.lucy-austrolopithicus afarensisorrorin tugenesis- oldest human ancestor walked on two legs paranthropus- lives in woods and grass lands (extinct) homohabilis- oldowan tradition of tool making. homo ergaster ( increased brain volume) homo erectus (Asia) first to migrate first fire usage in kenya homoheidelbergensis similar brain capacity to modern - [Oestrogen Or Estrogen](https://www.elearning.dlife.in/lds-course-notes/oestrogen-or-estrogen-14/) - Notes:Oestrogen or Estrogen is one of two main sex hormones that women have. The other one is progesterone . Estrogen is responsible for female physical features and reproduction.Men have oestrogen too, but in smaller amounts.Estrogen is a category of sex hormones responsible for the development and regulation of the female reproductive system and secondary sex - [Insulin Resistance & Hypertension](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-hypertension-23/) - Notes: increased renal Na reasbsorptionactivation of the sympatehtic nervous systemIon transport alterationhypertrophy of resistance vessels - [Fructose](https://www.elearning.dlife.in/lds-course-notes/fructose-10/) - Notes: - [Strategies for Self-Promotion](https://www.elearning.dlife.in/lds-course-notes/strategies-for-self-promotion-7/) - Notes:Self promotion.One baby step at a time.- Create good websiteSend introductory letter by email with introduction and services to offer.- Use of social media.- Keep database of all clients.- Work on refferals.Never Give Up. Some plans will succeed, some will fail.Failure shud be taken as lesson, to turn into opportunities. - [How To Cook Low Carb Foods](https://www.elearning.dlife.in/lds-course-notes/how-to-cook-low-carb-foods-9/) - Notes:Advanced Glycation End Products ( AGE) .Dietary advanced glycation end products ( dAGE's) are known to contribute to increased oxidative stress and inflammation. These are linked to the recent epidemics of diabetes and cardiovascular disease. Modern day dietary habits are largely heat processed leading to high levels of advanced glycation end products . Many packaged - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-28/) - Notes: - [Protease](https://www.elearning.dlife.in/lds-course-notes/protease-17/) - Notes:Types of Proteases:1. Aspartic - Pepsin and Renin2. Cysteine - Thiol group - Papain and Capsases3. Metallo - Zn - MMPs, Carboxypeptidase4. Serine - Serine, Histidine, Aspartate - Trypsin, Chymotrypsin, Elastase5. Threonine - Proteosome complex6. Glutamic - fungal enzymes, not in humans7. Asparagine - Specific bacterial enzymesBiological role: Digestion & catabolism of proteins, hydrolysis of - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-25/) - Catalyzes the hydrolysis of TGL into free FA and glycerol, playing vital role in lipid metabolism and digestion. Predominantly produced in pancreas. Energy metabolism and production of biofuels. Types: Pancreatic, Lingual & Gastric, Hepatic, MicrobialPancreatic insufficiencyHigh Lipases levels:1. Acute & Chronic Pancreatitis2. Gallbladder issues3. Bowel obstruction4. Metabolic disorders5. Kidney diseases6. Infections7. MedicationsLow Lipases:1. Chronic pancreatitis2. Cystic fibrosis3. Pancreatic - [Strategies for Self-Promotion](https://www.elearning.dlife.in/lds-course-notes/strategies-for-self-promotion-6/) - Strategies for self-promotion - create happy and satisfied clients. focus on getting good results than money. strategies - website social media - to spread your work, expertise, successprofessionally done website - register a domain for your business, get a hosting account with good hosting company. quickest to get up and running - WordPress. invest in a good template from sites - [How To Cook Low Carb Foods](https://www.elearning.dlife.in/lds-course-notes/how-to-cook-low-carb-foods-8/) - how to cook low carb foods - advanced glycation end products - AGEs - dietary AGEs - known to contribute to increased oxidative stress and inflammation > diabetes and CVDmodern day cooking - heat processed diet > high levels of AGEspackaged foods > high AGEs as heat processedAGEs - naturally formed inside body when protein/fat combine with - [Reading Nutrition Labels](https://www.elearning.dlife.in/lds-course-notes/reading-nutrition-labels-7/) - reading nutrition labels - ex. peanut butter or almond butter - low carb, high fat but also have refined sunflower oil or even soybean oil - both are harmfulanother ex. - type of protein added. nutrition label may show perfect protein content but list of ingredient can show Gluten added in it. Gluten - is also - [Coaching Skills](https://www.elearning.dlife.in/lds-course-notes/coaching-skills-5/) - questions - how come you want to do a low carb diet?where or who told you about this diet?whats your objective or goal of doing a low carb diet?what benefits are you looking for from this diet?short term or long term?what are your expectations from me?what food preferences are there? taste etc - to tailor a - [Managing LCHF In Social Functions](https://www.elearning.dlife.in/lds-course-notes/managing-lchf-in-social-functions-5/) - Notes:n LCHF or keto diet, skipping breakfast is the normal part of the lifestyle. Some may skip lunch and live on breakfast and dinner schedule. So essentially one is settled on two meals a day. A few cups of coffee in between is the most that add to the two meal a day lifestyle. For the - [Managing LCHF While Travelling](https://www.elearning.dlife.in/lds-course-notes/managing-lchf-while-travelling-7/) - Managing LCHF while traveling - soaked nuts like almonds or unsoaked nuts like walnuts or peanutsmacadamia nuts, brazil nuts, sunflower seeds, melon seedswhey protein - MCT powder with whey protein can be mixedketo coffee + MCT powdercoconut milk tetrapak can be used as a milk in coffeeAmul fresh cream - if staying in a hotel - - [Diet & Supplements Goal For MetX Syndrome](https://www.elearning.dlife.in/lds-course-notes/diet-supplements-goal-for-metx-syndrome-8/) - Diet and supplements Goal for MetX syndrome - per meal carb tolerance - presuming no exogenous insulin is usedfollow transition plan as first step. Also, keep in mind the medications of client too.check carb tolerance per meal - check glucose levelsFBS: ~90 mg/dL (anything between 70 to 100 is fine to go with).PPBS 1 Hr.: 140 - [Aldosterone](https://www.elearning.dlife.in/lds-course-notes/aldosterone-16/) - A corticoid is a type of steroid hormone produced in the adrenal cortex, which is the outer layer of the adrenal glands. The two main types are glucocorticoids (primary being cortisol), which manage stress and inflammation, and mineralocorticoids (primary being aldosterone), which regulate salt and water balance. Glucocorticoids regulate the immune system, suppress inflammation, and - [Managing LCHF While Travelling](https://www.elearning.dlife.in/lds-course-notes/managing-lchf-while-travelling-6/) - Notes:Carry as mush possible from home to avoid from going off the wagon.Short Journeys and Long Journeys :-- Carry Soaked Nuts like walnuts, almonds or peanuts.- Premium nuts like macadamia, Brazil nuts are good.- We can also carry bit of cashew nuts though its ambit carb.- Dry items sunflower seeds, melon seeds can also be - [Diet & Supplements Goal For MetX Syndrome](https://www.elearning.dlife.in/lds-course-notes/diet-supplements-goal-for-metx-syndrome-7/) - Notes: Primary dietary Goals - - Carb is the limit, Protein is Target and Fat is the Lever.So, Ideally 15 to 20 % should be the protein - Calorie in a day. For a sedentary life style individual protein should be 1.2 grams / kg body weight and max should be 1.8 grams /kg of body weight. - [Planning For Transition](https://www.elearning.dlife.in/lds-course-notes/planning-for-transition-8/) - Notes:A Ketogenic diet is s sub group of LCHF diet.Pre Transition Preparation for transitioning to the new life style .1. A blood glucose monitoring meter if dealing with a diabetic. As transitioning begins always insist for - Pre meal readings- meal Macro details ( Carbs/Proteins/fats)- 2 hrs PPBS number.- If on sulphonylurea drugs or insulin, insists - [Devices & Gadgets](https://www.elearning.dlife.in/lds-course-notes/devices-gadgets-7/) - Notes:Types of ketone Bodies -1. Acetoacetate - Created from breakdown of fatty acids.2.Either converted into BHB or turned into acetone.3. Beta -Hydroxybutyric Acid - Formed from acetoacetate. Not technically a ketone because of its structure, but we condos it as one within the keto diet.4. Acetone - Created as side product of acetoacetate.Breaks down quickly.Is - [Thyroid Stimulating Hormone – TSH](https://www.elearning.dlife.in/lds-course-notes/thyroid-stimulating-hormone-tsh-21/) - Thyroid-stimulating hormone (TSH) is a glycoprotein hormone produced by the pituitary gland that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3), which are essential for metabolism, growth, and development of almost every tissue in the body. T4 and T3 are essential to maintain the body’s metabolic rate, heart, and digestive functions, - [Devices & Gadgets](https://www.elearning.dlife.in/lds-course-notes/devices-gadgets-6/) - Devices and gadgets -blood glucose testing - blood glucose meter - consider cost of strips, availability of strips, accuracy, free replacementAccu-Check Active, Performa - 2 models used widely in dLifeJ&J simple select and Bayer's Contour meters. tooAbbott Freestyle Libre - 2 models - Freestyle Libre and Freestyle Libre Pro. 14 day continuous recording of blood glucose, - [The Easy Transition Plan](https://www.elearning.dlife.in/lds-course-notes/the-easy-transition-plan-9/) - The easy transition plan - start with a clean slate keto is an option but not a compulsionalways recommend starting with. LCHF range of carbswith personal threshold of carb tolerance, we do not restrict anything3 week transitioning - gastric distress may occurweek 1. - breakfast to LCHF first, keep lunch, dinner, snacking unchanged. Finalize LCHF breakfastweek 2 - [Planning For Transition](https://www.elearning.dlife.in/lds-course-notes/planning-for-transition-9/) - planning for transition - pre transition preparation - blood glucose monitoring meter if dealing with diabetic. - pre-meal reading, meal macro details - carbs, proteins, fats, 2 hr PPBS number, if on insulin or sulphonylurea drugs - insist for 3 hr number tooBP monitor - handy when on keto and transition blueskitchen balance - necessary to train - [Medical Tests Before Transitioning](https://www.elearning.dlife.in/lds-course-notes/medical-tests-before-transitioning-9/) - medical tests before transitioning - necessary tests - CBC, cardiac profile, inflammation markers - hsCRP, ESR - normally a part of CBC, LIPID profile, liver function test, kidney function tests - including microalbumin urea, Vitamin profile tests, enzyme profile tests, fasting insulin, diabetes profile - FBS, PPBS, A1C, urine test, abdomen USG, c-peptide & GAD 65 (to - [Data Capturing](https://www.elearning.dlife.in/lds-course-notes/data-capturing-9/) - data capturing - height in cms or inches, weight in kgs, ideal body weight calculation, waist measurement in inches or cms, BMI, waist to hip ration, waist size, body fat %, blood markers / lab reports = blood sugar levels, HbA1C, insulin levels, liver function test, kidney function test, lipids, Vit B12, D levels, inflammatory markets like - [Somatostatin](https://www.elearning.dlife.in/lds-course-notes/somatostatin-24/) - Somatostatin is a peptide hormone that inhibits the release of many other hormones. It acts by both endocrine and paracrine pathways. It is secreted by a broad range of tissues, including delta cells at several locations in the digestive system, namely the pyloric antrum, the duodenum and the pancreatic islets, and regions of CNS outside - [Secretin](https://www.elearning.dlife.in/lds-course-notes/secretin-14/) - Secretin is a peptide hormone that is produced by the S cells of the duodenum when partly digested food (acidic chyme) from the stomach enters. It stimulates the release of sodium bicarbonate and water from the pancreas and liver to help neutralize acidic chyme and aids in digestion. Secretin also regulates water homeostasis, gastric acid - [Adrenaline](https://www.elearning.dlife.in/lds-course-notes/adrenaline-30/) - Notes cover noradrenaline (norepinephrine) as well.Adrenaline (epinephrine) and noradrenaline (norepinephrine) are both hormones and neurotransmitters from the catecholamine family (hormones derived from the amino acid tyrosine), produced by the adrenal glands and neurons in the CNS, playing a key role in the fight-or-flight response by increasing heart rate, blood flow, and awareness. While adrenaline is - [Myth: PUFA Loaded Vegetable Oils Are Better Than Saturated Fat](https://www.elearning.dlife.in/lds-course-notes/myth-pufa-loaded-vegetable-oils-are-better-than-saturated-fat-54/) - Notes:fructoseby product of fructose the LDL particles are metabolized under the blood vessel on the effect of sunlight/vit D - [Progesterone](https://www.elearning.dlife.in/lds-course-notes/progesterone-21/) - Progesterone is an endogenous steroid hormone that belongs to a group of steroid hormones called the progestogens and is the major progestogen in the body. The progestogens are one of three types of sex hormones, the others being estrogens (e.g. estradiol) and androgens (e.g. testosterone).During the menstrual cycle, the corpus luteum is stimulated by LH - [Test And Numbers & CAC Score](https://www.elearning.dlife.in/lds-course-notes/test-and-numbers-cac-score-16/) - Notes:A LIPID PANEL TEST MEASURES THE LEVEL OF SPECIFIC LIPIDS IN THE BLOOD TWO IMP LIPIDS- CHOL AND TRIGL ARE TRANSPORTED IN THE BLOOD BY LIPOPROTEINSEACH TYPE OF LIPOPROTEIN IS A COMBI OF CHOL,TRIGL,PROTEIN,AND PHOSPHOLIPID MOLECULEHDL- TAKES UP EXCESS CHOL AND CARRIES IT TO THE LIVER FOR REMOVAL LDL- DEPOSITS THE EXCESS CHOL IN THE WALLS OF - [Background And Current Status](https://www.elearning.dlife.in/lds-course-notes/background-and-current-status-10/) - Notes:DIETARY CHOL HAS NO EFFECT ON SERUM CHOL AND THAT CHOL IS A VERY WEAK MARKER FOR THE RELATIONSHIP WITH CVD - [The Easy Transition Plan](https://www.elearning.dlife.in/lds-course-notes/the-easy-transition-plan-8/) - Notes:3 week transition to LCHF -W1 - switching break fast to LCHF diet, Lunch and dinner and snacking unchanged.W2 - Breakfast fixed lunch shift to LCHFdiet. Now, Breakfast and lunch on LCHF.W3 - Switch dinner to LCHF meals. Whole transition complete to LCHF . Snacks shud be completely off . Only 3 meals a day - [Medical Tests Before Transitioning](https://www.elearning.dlife.in/lds-course-notes/medical-tests-before-transitioning-8/) - Notes:For those who can afford :-Calcium Score Test or CAC ( Coronary artery calcium . This test costs around 6,000 to 7000 on an average, this test should be done to know the extent of plaque in arteries.This test can reveal what no other tests like Lipids, Cardiac Markers etc can ever reveal.Necessary Tests :-- - [Oestrogen Or Estrogen](https://www.elearning.dlife.in/lds-course-notes/oestrogen-or-estrogen-20/) - Estrogen is a group of steroid hormones that are crucial for the development of female reproductive systems and secondary sex characteristics. Estrogen and progesterone are the two main sex hormones that women have. While the ovaries are the primary producers, the adrenal glands, fat tissue, and the placenta during pregnancy also produce it in smaller - [Peptide YY](https://www.elearning.dlife.in/lds-course-notes/peptide-yy-21/) - Peptide YY (PYY) is a gut hormone that helps regulate appetite and digestion. It is primarily released by cells in the ileum and colon when food (especially fats/proteins) reaches there. High-calorie foods lead to higher PYY release. Its levels are the highest ~2 hours after eating. PYY can also be stimulated by digestive juices (e.g. - [Understanding Autoimmune Conditions, and the Role of Carnivore Diet in Management](https://www.elearning.dlife.in/lds-course-notes/understanding-autoimmune-conditions-and-the-role-of-carnivore-diet-in-management-11/) - Understanding autoimmune conditions, and the role of carnivore diet in management - body's immune sys > attacks its own tissue mistakenly > hashimoto's thyroiditis, ulcerative colitis, RA, crohn's disease > idiopathic (cause unknown) > diet is a significant factormany plant food contain defense chemicals like lectins, phytates, oxalates > can exacerbate inflammation and immune dysfunctioncarnivore diet - [Protease](https://www.elearning.dlife.in/lds-course-notes/protease-16/) - Proteolytic enzymes (protease) are enzymes that break protein. made by animals, plants, fungi, and bateria. Also found in some foods such as pineapple, papayas, yogurt/kefir, ginger, sauerkraut, miso, kiwi. - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-21/) - Amylase helps in digestion of carbohydrates, breaking down complex polysaccharides into simpler, absorbable forms. Amylase is mainly produced in the Saliva and Pancreas.Serum Amylase Test (Pancreas disorder) - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-24/) - Lipase is enzyme that catalyzes the hydrolysis of triglycerides into free fatty acids and glycerol, playing a vital role in lipid metabolism and digestion across various organisms. Lipase produced primarliy by pancreas but also by mouth, stomach, intestine. - [The Rise of Modern Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-rise-of-modern-chronic-diseases-23/) - Chronic diseases - including cancer, diabetes, hypertension, stroke, heart disease, respiratory disease, arthritis, obesity, and oral diseases - can lead to hospitalization, long-term disability of life, and death. - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-89/) - Proteins break into amino acidsFats break into fatty acids & glycerolCarbohydrates break into simple sugars - [Myth: Plant Based Diets Are The Best](https://www.elearning.dlife.in/lds-course-notes/myth-plant-based-diets-are-the-best-33/) - Notes:there was no financial gain for our civilization - why did we move into a vegetarian diet?we didnt follow the guidelines, but definitely switched to bad fats and simple carbs. if we remove that, and fall back to the say old marathi diet- will - [Data Capturing](https://www.elearning.dlife.in/lds-course-notes/data-capturing-8/) - Notes: - [Understanding Autoimmune Conditions, and the Role of Carnivore Diet in Management](https://www.elearning.dlife.in/lds-course-notes/understanding-autoimmune-conditions-and-the-role-of-carnivore-diet-in-management-10/) - Notes:The nature of Autoimmune diseases:-Autoimmune diseases occur when the body's immune system mistakenly attacks its own tissues. Examples include Hashimoto's thuroiditid, Crohn's disease,Ulcerative colitis and rheumatoid arthritis. These diseases are called as idiopathic ( Cause Unknown). emerging research points to diet as a significant factor.The problem with Plant Based Diets :-1. Contains defence chemicals - - [The Metabolic Approach to Cancer: A Holistic and Evolving Paradigm](https://www.elearning.dlife.in/lds-course-notes/the-metabolic-approach-to-cancer-a-holistic-and-evolving-paradigm-5/) - Notes:Cancer Treatment has undergone remarkable advances over the years. However the persistent challenges of treatment resistance and side effects and increasing incidences rates demand innovative strategies. One emerging approach is metabolic approach cancer, which complements conventional treatments by addressing the fundamental energy metabolism of cancer cells. Understanding metabolic approach to cancer:-The metabolic approach challenges the century - [Understanding Migraines: Causes, Connections, and Management](https://www.elearning.dlife.in/lds-course-notes/understanding-migraines-causes-connections-and-management-8/) - Understanding migraines - causes, connections and management - complex neurological conditionattacks of head pain >. can last from few hours to several days- nausea, vomiting, sensitivity to light, sound, visual disturbances, dizziness or vertigo, cognitive impairmentsmigrane causes - pathophysiology - 1. vascular - vasodilation in brain causes migraine, vasoconstriction in brain causes aura - no lobger valid2. - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-27/) - Notes:Metabolities : these are the product of metabolism - meaning the body breaking down food, drugs or its own tissue that are needed for growth, reproduction etcafferent: carries signals to the central nervous system eg sensory info like you touching a hot vesselEfferent: carries signal from the brain or CNS to the organs and parts - [Norepinephrine](https://www.elearning.dlife.in/lds-course-notes/norepinephrine-21/) - Covered in adrenaline notes. - [Understanding Migraines: Causes, Connections, and Management](https://www.elearning.dlife.in/lds-course-notes/understanding-migraines-causes-connections-and-management-7/) - Notes:Migraines are more than just severe headaches. They are complex neurological condition that significantly impact the quality of life for million people.What are migraines -Migraines are recurrent attacks of head pain that can last for few hours to several days.. Migraines can be accompanied by symptoms such as :-- Nausea, Sensitivity to light and sound, - [Role of Metabolic Therapies in Neurological and Systemic Health](https://www.elearning.dlife.in/lds-course-notes/role-of-metabolic-therapies-in-neurological-and-systemic-health-7/) - Notes:Understanding Metabolic Therapies - 1. Foundations of Metabolic Therapy : Metabolic therapies leverage dietary and fasting protocols to shift the body's energy metabolism from glucose to ketones an alternative fuel source. This metabolic shift enhances mitochondrial function, improves energy efficiency and promotes resilience against cellular stress.2. The role of Mitochondria - Power House of cells , - [Melatonin](https://www.elearning.dlife.in/lds-course-notes/melatonin-24/) - Melatonin is an amine hormone (derived from the amino acid tryptophan) produced primarily in the pineal gland in the brain in response to darkness (eyes detect reduced light) to synchronize the sleep-wake cycles, including sleep-wake timings and BP regulation. Melatonin levels at night-time are at least 10-times higher than at daytime. Infants' melatonin levels become - [Ketogenic Diet & Mental Health](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-mental-health-9/) - Notes:Gut Brain Connection - A healthy gut microbiome, supported by fibre, probiotics and pre biotic plays a significant role in mood regulation.Essential Nutrients - Omega 3 fatty acids, B vitamins, Vitamin D, Magnesium, and zinc are crucial for neurotransmitter production and brain health.Personalised Nutrition - Tailored interventions based on individual needs enhance efficacy.Ketogenic diet - - [Role of Metabolic Therapies in Neurological and Systemic Health](https://www.elearning.dlife.in/lds-course-notes/role-of-metabolic-therapies-in-neurological-and-systemic-health-6/) - Role of metabolic therapies in neurological and systemic health - parkinsons - dopamine depletion - levodopa med - does not halt disease progression, gives symptomatic reliefketo may improve motor symptoms and energy levelsalzheimers - most common cause of dementia - memory loss, cognitive decline. Keto mitigates AD symptomsALS - amyotrophic lateral sclerosis - progressive degeneration of - [Ketogenic Diet & Mental Health](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-mental-health-8/) - ketogenic diet & mental health -def in. vit B12, Vit D - anxiety, depression, intellectual disabilitiesmental health meds >. IR, wt gain, T2Dgut brain connection, essential nutrients - omega-3 fatty acids, Vit B, D, magnesium, zinc - crucial for neurotransmitter production and brain health, personalized nutritionthe keto diet - enhanced energy supply, reduced inflammation, balanced - [Ketogenic Diet For Alzheimer’s Disease](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-for-alzheimers-disease-8/) - Ketogenic diet for Alzheimer's disease - brain has lost ability to properly metabolize glucose. but brain can use ketonesIR > may cause Alzheimer'sketone body mechanism - ketone bodies as alternative fuel - ketone - beta hydroxybutyrate (BHB) - can fuel nueronsMCT - medium chain triglycerides - rapidly converted ti ketones by liver. MCT supplements > increased ketones - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-88/) - Notes:1, how deep do i go? do i learn it by heart? did iterative e - [Ketogenic Diet & Polycystic Kidney Disease](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-polycystic-kidney-disease-7/) - ketogenic diet and polycystic kidney disease - PKD - genetic diseasehypertension - one of the earliest symptoms of PKD - [Low Carb & Ketogenic Diet For Kidney Disease](https://www.elearning.dlife.in/lds-course-notes/low-carb-ketogenic-diet-for-kidney-disease-7/) - Low carb and ketogenic diet for kidney disease - CKD can be caused by - high BP, diabetes (diabetic kidney disease), high cholesterol, kidney infections, glomerulonephritis, polycystic kidney disease, blockages in flow of urine, long term use of certain meds like NSAIDshead of nephron is called glomerolus - some nephrons die - increase work load on others - [Glucose Ketone Index — GKI — Guide to Its Usage in Cancer and Other Health Conditions](https://www.elearning.dlife.in/lds-course-notes/glucose-ketone-index-gki-guide-to-its-usage-in-cancer-and-other-health-conditions-7/) - Glucose ketone index - GKI - guide to its usage in cancer and other health conditions - cancer - cell division out of control - dysregulated wayinsult to oxidative phosphorylationimpact has to be chronic and gradual. reactive oxygen species increase - carcinogenic. onco genes are facilitators of converting to fermentationcancer - metabolic disorder of mitochondria - - [Thyroid Function Test (TFT)](https://www.elearning.dlife.in/lds-course-notes/thyroid-function-test-tft-9/) - Thyroid function test - TSH - normal - 0.4 - 4.0 mIU/L FT4 - normal range - 0.7 - 1.8 ng/dLFT3 - normal range - 2.3 - 4.2 pg/mLthyroglobulin (Tg) - normal range - 35 ng/mL. protein made by thyroid gland - high levels > thyroid cancer or goiterthyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TgAb) - - [Ketogenic Diet For Alzheimer’s Disease](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-for-alzheimers-disease-7/) - Notes:Inability of brain to metabolise glucose is cause of Alzheimer. - [Ketogenic Diet & Polycystic Kidney Disease](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-polycystic-kidney-disease-6/) - Notes:Polycystic Kidney disease is a genetic disorder characterised by the formation of numerous cysts in the Kidneys leading to kidney enlargement and impaired functions. Two forms of PKD - AD PKD and Autosomal recessive polycystic kidney disease.1. Autosoml Dominant Polycystic Kidney Disease -- This is the most prevalent form accounting for about 90% of PKD cases. - [Low Carb & Ketogenic Diet For Kidney Disease](https://www.elearning.dlife.in/lds-course-notes/low-carb-ketogenic-diet-for-kidney-disease-6/) - Notes:CKD can be caused by -- High Blood Pressure- Overtime , this can put strain, on the small blood vessels in the kidneys and stop kidneys from working properly.- Diabetes - Too much glucose in ones blood can damage thebtiny filters in the kidneys also called as diabetic kidney disease.- High Cholestrol - This can - [Luteinizing Hormone](https://www.elearning.dlife.in/lds-course-notes/luteinizing-hormone-15/) - Luteinizing hormone (LH) is a pituitary hormone regulated by the hypothalamic-pituitary-gonadal (HPG) axis, plays a crucial role in sexual development and reproduction. FSH and LH are two main gonadotropins (influences gonads). In females, LH triggers ovulation and the formation of the corpus luteum (temporary endocrine gland in the ovary that forms after ovulation). In males, - [Glucose Ketone Index — GKI — Guide to Its Usage in Cancer and Other Health Conditions](https://www.elearning.dlife.in/lds-course-notes/glucose-ketone-index-gki-guide-to-its-usage-in-cancer-and-other-health-conditions-6/) - Notes:The Glucose Ketone Index - is available metric used to assess metabolic health by examining the blood glucose and ketone levels. Summary - The Glucose Ketone Index is more than just a number . Its a window into body metabolic state. - [Thyroid Function Test (TFT)](https://www.elearning.dlife.in/lds-course-notes/thyroid-function-test-tft-8/) - Notes:Notes:The thyroid gland plays a crucial role in regulating the body's metabolism thru the secretion of thyroid hormones - Thyroxine ( T4) and triiodothyronine T3 . Thyroid function test are essential for diagnosing thyroid dysfunction., which can manifest as hypothyroidism, hyperthyroidism or thyroid cancer.Methods of Thyroid function Testing -1. Thyroid Stimulating Hormone ( TSH )Measurement - [Follicle-stimulating Hormone](https://www.elearning.dlife.in/lds-course-notes/follicle-stimulating-hormone-27/) - Follicle-stimulating hormone (FSH) is a pituitary hormone that is crucial for reproductive organ function and fertility in both sexes. It promotes egg development in females and sperm production in males. Hypothalamus releases gonadotropin-releasing hormone (GnRH), which signals the pituitary to release FSH and luteinizing hormone (LH). In females, FSH stimulates the growth of ovarian follicles, - [Liver Function Test (LFT)](https://www.elearning.dlife.in/lds-course-notes/liver-function-test-lft-8/) - Liver function test - serum bilirubin - will go high if liver not working well - jaundiceAST - high in heart muscles, low in kidney and pancreashigh AST today and after 1 months also > liver cirrhosislow AST - in preg womenhepatotoxic meds - high ASTaLT/AST ratio - always less than 1 - in viral hepatitis - [LIPID Panel TEST (LPT)](https://www.elearning.dlife.in/lds-course-notes/lipid-panel-test-lpt-6/) - Lipid panel test (LPT) - for CVD riskpurpose of test - diagnosis, screening, monitoring, treatment evaluationcomponents of lipid panel test - total cholesterol - sum of all cholesterol types in blood< 200 mg/dL - normal, borderline high - 200-239 mg/dL, high >= 240 mg/dLLDL - bad - high levels can lead to plaque buildup in arteries< 100 - [Iron Profile Test](https://www.elearning.dlife.in/lds-course-notes/iron-profile-test-8/) - Iron profile test - components of an Iron panel - 1. serum iron - amnt of iron in blood thats bound to transferrin.normal value - 60-170 micrograms/deciL for men, 40-155 mcg/dL for womenlow levels - iron def, high levels - iorn load/recent ingestion of iron2. total iron binding capacity - TIBC - measures blood's capacity to bind iron - [Kidney Function Test (KFT)](https://www.elearning.dlife.in/lds-course-notes/kidney-function-test-kft-10/) - Kidney function test - kidneys - 12 cm in size - below liversize is not equal - filters blood1 million nephrons - in eachchronic kidney diseases - feeling tired, low energy, trouble in concentration, sleep apnea - noticed in CKD - freq. urination, night time urination, foamy urine = albumin portion in urinesodium retains waterloss of - [Complete Blood Count (CBC) Tests](https://www.elearning.dlife.in/lds-course-notes/complete-blood-count-cbc-tests-13/) - Common blood tests - Complete blood count tests (CBC) -liquid part - plasma proteincells - RBC - erythrocytes, WBC - liquocytes, plateletes - thrombocytesRBCs - highest number. - 45% of bloodhigh RBC - high altitude, physical exercise high - natural, low RBC - def of B21, folate, iron - anemiaavg life span of RBC - 120 daysRBCs - [Vasodilators](https://www.elearning.dlife.in/lds-course-notes/vasodilators-10/) - vasodilators - dilate blood vessels - allowing blood to flow thru easily. Hydralazine - used in Indiamode of action - relaxes muscles in your blood vessels to help them dilate. also used in heart failureside effects - chest pain, GI issues, loss of appetitecontraindications - preg, below 18 years of age, coronary artery diseasedrug interactions - [Diuretics](https://www.elearning.dlife.in/lds-course-notes/diuretics-10/) - diuretics - water pillsin US - thiazide type diuretics - one of the first line drug treatmentments for high BP - either as monotherapy or in combination with calcium channel blockers, ACE inhibitors or angiotensin 2 receptor antagonistsmode of action - help kidneys eliminate excess salt and water from body's tissues and bloodside effects - - [Centrally Acting Antihypertensives](https://www.elearning.dlife.in/lds-course-notes/centrally-acting-antihypertensives-9/) - centrally acting antihypertensives - blocking signal from brain to nervous sys that speed up ur heart and narrow your veins and arteriesreduces neuronal release of norepinephrine to heart and peripheral circulationused fir drug withdrawal, menopausal flushingside effects - sedation, impotence, fever, dry mouthcontraindications - to be avoid by patients taking psychiatric meds, pregbrands - - [Calcium Channel Blockers or Calcium Antagonists](https://www.elearning.dlife.in/lds-course-notes/calcium-channel-blockers-or-calcium-antagonists-10/) - calcium channel blockers or calcium antagonists = disrupt movement of calcium thru calcium channelsmay slow your heart rate, relieve chest pain and control irregular heart beatside effects - fast heartbeat, flushing, rash, swelling in feet, lower legscontraindications - avoid grapefruit products with this - can affect heart rate and BP, severe hypotension, pulmonary congestionbrands - amlopin/amlodac, - [Beta Blockers](https://www.elearning.dlife.in/lds-course-notes/beta-blockers-10/) - Beta blockers - beta adrenergic blocking agents - reduce BPmode of action - blocks effect of epinephrine or adrenaline > causes heart to beat slowly and with less forceopen arteries and veins to improve blood flowalso useful in - angina, cardiac healing after heart attack, heart failure, heart rhythm problem like atrial fibrillation or palpitationsside - [Angiotensin II Receptor Blockers](https://www.elearning.dlife.in/lds-course-notes/angiotensin-ii-receptor-blockers-9/) - Angiotensin 2 receptor blockers - Angiotensin 2 antagonists (AT) - modulate renin-angiotensin sys. main uses - treatment of hypertension, diabetic nephropathy, congestive heart failuremode of action - blocks action of angiotensin 2 by preventing angiotensin 2 from binding to angiotensin 2 receptors > enlarged blood vessels /relaxed/dilate - BP reducedif you have kidney disease, this helps in controlling - [Alpha Blockers](https://www.elearning.dlife.in/lds-course-notes/alpha-blockers-10/) - Alpha Blockers - or alpha-adrenoreceptor antagonists - act on alpha-adrenergic receptorsonly Prazosin > used in BHP (benign prostatic hyperplasia) and resistant hypertension in Indiamode of action - blocks effect of nerves in sympathetic nervous system - done by binding to alpha receptors in smooth muscle or blood vessels reversibly and irreversibly)side effects - sudden drop - [Angiotensin Converting Enzyme Inhibitors](https://www.elearning.dlife.in/lds-course-notes/angiotensin-converting-enzyme-inhibitors-10/) - Angiotensin converting enzyme inhibitors - ACE inhibitors - primary for high BP and heart failurethis med inhibits active of enzyme ACE > decreases production of angiotensin 2 > less blood volume > low BP (blood vessels enlarged or dilated or relaxed)also slow progression of kidney disease and atherosclerosis ( narrowing of arteries caused by plaque) , - [Hypertension Medications](https://www.elearning.dlife.in/lds-course-notes/hypertension-medications-6/) - Hypertension medications - reduce BP - BP - usually refers to pressure in large arteries of systemic circulationhigh BP - heart attack/stroke, cause hardening and thickening of arteries (atherosclerosis) > heart attack/stroke/other complicationshypertensive crisis - medical emergency - BP rises above 180/120 rapidlyhigh BP > damage to your organssymptoms - blurry vision, dizziness, lightheadedness, severe headaches, - [Leptin](https://www.elearning.dlife.in/lds-course-notes/leptin-25/) - Leptin is a peptide hormone produced primarily by fat cells that regulates long-term energy balance by signaling to the brain to suppress appetite and increase energy expenditure (not just from one meal to the next). It is a key regulator of body weight and also influences other physiological functions like metabolism, reproduction (stimulates gonadotropins in - [High Intensity Interval Training – HIIT](https://www.elearning.dlife.in/lds-course-notes/high-intensity-interval-training-hiit-9/) - Notes: - [Liver Function Test (LFT)](https://www.elearning.dlife.in/lds-course-notes/liver-function-test-lft-7/) - Notes:Also known as liver chemistry are blood test that provide information about the state of liver health or identify liver damage. These test measure various enzymes, proteins and substances produced or processed by the liver.Purpose -1. Screening for Liver disease :2. Monitoring Disease Progression 3. Evaluating Symptoms Components of Liver Function Tests ;1. Alanine Aminotransferase ( ALT) - [LIPID Panel TEST (LPT)](https://www.elearning.dlife.in/lds-course-notes/lipid-panel-test-lpt-5/) - Notes:Also called as lipid Profile test . Measures the levels of specific lipids in blood.Purpose of test - Diagnosis, Screening, Monitoring, Treatment evaluation .Components of Lipid profile Test :_1.Total Cholestrol - Sum of all cholesterol in blood.2. LDL - Often referred as bad cholesterol . High level can create plaque in arteries.3.HDL - Good cholesterol. - [Iron Profile Test](https://www.elearning.dlife.in/lds-course-notes/iron-profile-test-7/) - Notes:An iron panel also known as Iron Studies or Iron Profile is set of blood tests that measure different aspects of iron metabolism to assess an individuals iron status. Here is a breakdown of the typical components included in an iron panel :Components of an Iron Panel :-1. Serum Iron - - It measures blood capacity - [Kidney Function Test (KFT)](https://www.elearning.dlife.in/lds-course-notes/kidney-function-test-kft-9/) - Notes:Kidney Function Test is also known as renal function tests ( RFT) are essential diagnostic toolset to asses the health and functionality.of the kidneys. These tests measure various substances in the blood and urine, providing insights into how well the kidneys filter waste products and maintain homeostasis.The kidneys are critical in filtering waste materials from - [Weight Loss Medications](https://www.elearning.dlife.in/lds-course-notes/weight-loss-medications-10/) - weight loss medication - orlistat (xenical) - reduces intestinal fat absorption by inhibiting enzyme pancreatic lipase - only work if fat intake is high. fecal incontinence, rare liver injurycetilistat - trial phase - same like orlistatlorcaserin (belviq/alfence) - reduces appetite by activating type of serotonin receptor - 5-HT2C - in hypothalamus - known to control appetite - [GLP1 Analogues](https://www.elearning.dlife.in/lds-course-notes/glp1-analogues-10/) - GLP-1 analogues - glucagon like peptide-1 receptor agonists - GLP-1 receptor agonists or incretin mimetics - for T2Dmode of action - copying/mimicking function of natural incretins - help lower post meal blood sugar levelsstimulate insulin release after eating , even before blood sugars start to rise - inhibiting release of glucagon by pancreas. glucagon - causes - [Exogenous Insulin](https://www.elearning.dlife.in/lds-course-notes/exogenous-insulin-9/) - exogenous insulin - basal or long-acting insulin - cloudy insulin - made by adding protamine to a mol of short-acting human insulin = to delay uptake in bloodpros - cheap, when given at midnight - can cover dawn effect, can be diluted with normal salinecons - peak can occur at irregular times, variable absorption rate, may - [Thiazolidinediones](https://www.elearning.dlife.in/lds-course-notes/thiazolidinediones-10/) - Thiazolidinediones - since 2000mode of action - decrease IR by forming new fat cells, primarily on arms, thighs, buttother benefits - preserve function of insulin producing cells, increase HDL, reduce TGside effects - water retention, wt gain, heart problems, liver failure, anemia, bone fractures, macular oedemacontraindications - caution in patients with heart problems, bladder cancer patients, - [Sulfonylureas and Meglitinides](https://www.elearning.dlife.in/lds-course-notes/sulfonylureas-and-meglitinides-10/) - Sulfonylureas and Meglitinides - glinidessulfonylureas - first oral antidiabetic agents - tobutamide, acetohexamide > first generation of SUs, 2nd generation > Gilbenclamide/glyburide, gliclazide, glipizide, third generation - glimepirideglinides (nateglinide, repaglinide) >. relatively recent additionmode of action - stimulate pancreas to produce more insulin.other benefits - cheap, glinides cause less hypoglycemia but still pose a riskside - [Sodium-Glucose Cotransporter-2 – SGLT2 – Inhibitors](https://www.elearning.dlife.in/lds-course-notes/sodium-glucose-cotransporter-2-sglt2-inhibitors-10/) - sodium-glucose cotransporter-2 - SGLT2 - inhibitors -used to treat T2D since 2013mode of action - inhibits glucose reasbsorption in proximal convoluted tubules of kidneyexert positive effects on CV sys like wt loss, decreased BP, preserving renal function, reduce TG, natriuresis, improve endothelial dysfunctionother benefits - reductions in heart diseasesside effects - genital and UTI, DKA, - [Dipeptidyl peptidase-4 – DPP4 – Inhibitors](https://www.elearning.dlife.in/lds-course-notes/dipeptidyl-peptidase-4-dpp4-inhibitors-10/) - Dipeptidyl peptidase-4 - DPP4 - inhibitors - lower high blood glucose levels - may be used in T2D treatment > slow the inactivation and degradation of GLP-1 - a hormone involved in removing glucose from gutmode of action - suppresses enzyme DPP4 - that breaks down incretin hormones > prolonged action of incretins.GLP-1 > stimulates pancreas beta - [Biguanides](https://www.elearning.dlife.in/lds-course-notes/biguanides-10/) - Biguanides - organic compound with. formula - HN(C(NH)NH2)2 - oral type 2 diabetic drugs - prevents production of glucose in liver - improves body sensitivity to insulin > reduces amount of sugar absorbed in intestine.usually supplied as polymers in salt form > as hydrochloridemode of action - reduces liver dump of glucose (glycogen to glucose)increases insulin sensitivity - [Alpha Glucosidase Inhibitors](https://www.elearning.dlife.in/lds-course-notes/alpha-glucosidase-inhibitors-11/) - Alpha Glucosidase Inhibitors - first one to get approval in USA was Acarbose - 1995 > then Miglitol in 1999 > Voglibose latest additionmode of action - slow down digestion and absorption of carbs by blocking enzyme alpha-glucosidase (which helps digesting carbs in SI) > less blood sugar peak > better blood sugar controlboth volibose, acarbose - [Diabetes Medications](https://www.elearning.dlife.in/lds-course-notes/diabetes-medications-4/) - Diabetes medications - oral pills, exogenous insulinoral pills - classified into 6 groups - alpha glucosidase inhibitorsbiguanidesdipeptidyl peptidas-4 - DPP4 -inhibitorssodium glucose cotransporter-2 - SGLT2 - inhibitorssulfonylureas and meglitinidesthiazolidinediones - [Insulin Resistance & Cardiovascular Disease](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-cardiovascular-disease-25/) - Poor BG control due to IR can cause oxidative stress and an inflammatory response which can lead to cell damage. IR can also lead to the development of dyslipidemia and the lipid triad – High TG, Low HDL, Presence of small, dense LDL.This triad, along with endothelial dysfunction (which can also be induced by IR/hyperinsulinemia), - [Insulin Resistance & Obesity](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-obesity-29/) - Obesity increases risk of many metabolic disorders (T2D, IR, fatty liver, dyslipidemia, hypertension, atherosclerosis, stroke, immune dysfunction, asthma, sleep apnea, osteoarthritis, neurodegeneration, gall bladder disease, cancer) largely due to its secretions of excessive adipokines (proteins that act as hormones). Obesity has two distinct characteristics:Energy intake > energy expenditureResetting of bodyweight set point at an increased - [Insulin Resistance & Endothelial Dysfunction](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-endothelial-dysfunction-26/) - Endothelial dysfunction is a condition where the cells lining the heart and blood vessels, the endothelium, become unhealthy, leading to narrowed arteries that reduce blood flow. Symptoms can include chest pain and shortness of breath, and it contributes to atherosclerosis and hypertension. Endothelium releases substances that control vascular relaxation and contraction. The dysfunction is caused - [Complete Blood Count (CBC) Tests](https://www.elearning.dlife.in/lds-course-notes/complete-blood-count-cbc-tests-12/) - Notes:Complete blood cell count is a common blood test that evaluates the composition and health of ones bodily measuring different components including red blood cells, white blood cells and platelets. It is commonly used to assess overall health and diagnose various medical conditions, including anemia, infection and leukaemia.Components of a CBC -White blood cell count - [Insulin Resistance & Dyslipidemia](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-dyslipidemia-23/) - Dyslipidemia is characterized by abnormal level of lipids in the blood, with following most common conditions: High LDL, Low HDL, High TG.TG/HDL ratio is considered a surrogate marker for IR. In one study, TG/HDL ratio of >2.75 in men and >1.65 in women are found to be highly predictive of MetS diagnosis. This ratio was - [Autophagy](https://www.elearning.dlife.in/lds-course-notes/autophagy-7/) - Autophagy - fundamental cellular process that eliminates molecules and subcellular elements, including nucleic acids, proteins, lipids, organelles, visa lysosome-mediated degradation to promote homeostasis, differentiation, development, and survival.diff mechanisms of autophagy - altered autophagy - emerged as a feature of aging across diverse species. auto - self, phagin - to eat - highly conserved pathway that degrades cellular - [Aids And Cautions](https://www.elearning.dlife.in/lds-course-notes/aids-and-cautions-9/) - aids and cautions - aids to help - water - lemon water + pink salt is a boon and almost a necessity in low carb diet as we lose more water in that and also electrolytes. this helps replenishing electrolytesblack coffee - good hunger killer. contains phytochemical compound called chlorogenic acid - green and roasted coffee beans - [Types of Intermittent Fasting](https://www.elearning.dlife.in/lds-course-notes/types-of-intermittent-fasting-9/) - types of intermittent fasting - easy - if not on keto/low carb high fat keto diet - then IF is hardstart with at least 12 hourswhat u can have - black coffee, green tea, salt lime water, water cannot have - dont fast if u have headache, on some meds etcfasting - beneficiary since at least 5th century - [The Role of Stress Management](https://www.elearning.dlife.in/lds-course-notes/the-role-of-stress-management-7/) - role of stress management - negative health effects of stress - heachaches, increased depression, heartburn, insomnia, rapid breathing, weakened immune sys, risk of heart attack, high blood sugar, pounding heart, high BP, fertility problems, stomachache, erectile dysfunction, low sex drive, missed periods, tense muscleschronic stres symptoms include - irritabolity, anxiety, depression, headaches, insomina- get regular activity - [Insulin Resistance & Osteoarthritis](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-osteoarthritis-21/) - IR is the central feature of MetS which includes 3 or more of following:hypertensionhigh TGlow HDLhigh waist circumferencehigh fasting glucoseIncreasing number of MetS components predict an increased occurrence and progression of osteoarthritis (OA).Rheumatoid arthritis (RA) is an autoimmune disease that causes long-term inflammation of the joints and sometimes other body tissues, too. Studies have found - [Insulin Resistance & Uric Acid](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-uric-acid-23/) - Uric acid is a natural waste product from the breakdown of purines both from food and produced in the body. Fructose can stimulate de novo purine synthesis and high fructose consumption can also increase the rate of purine degradation, both causing high uric acid production.Purine-rich foods include liver, anchovies, mackerel, dried beans and peas, and - [Insulin Resistance & Cancer](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-cancer-24/) - IR / hyperinsulinemia is associated with obesity. And obesity has been associated with an increased risk of various cancers – esophageal, pancreatic, colorectal, breast, endometrial, kidney, thyroid, liver, gallbladder. Obesity appears to be one the most important risk factors for cancer. So, indirectly IR is driving cancer up.Cytokine production in obese adipose tissue creates a - [Vasodilators](https://www.elearning.dlife.in/lds-course-notes/vasodilators-9/) - Notes:VAsolidators are medicines that dilate widen blood vessels, allowing blood to flow more easily through.Some act directly on the Smoot muscle cell lining the blood vessels. There are many vasodilators but we will discuss.only Hydrlazine which is used in BP in India.Mode of action -Hydralazine is a vasodilator that works by relaxing the muscles in - [Diuretics](https://www.elearning.dlife.in/lds-course-notes/diuretics-9/) - Diuretics are also called water pills . In the United sates , the JNC8 recommends thiazide - type diuretics to be one of the first line drug treatment for hypertension, either as mono therapy or in combination with calcium channel blockers., ACE inhibitors or angiotensinII receptors antagonists.Diuretics help the kidneys eliminate excess salt water from - [Centrally Acting Antihypertensives](https://www.elearning.dlife.in/lds-course-notes/centrally-acting-antihypertensives-8/) - Notes:Central acting agent lower ones heart rate and reduce ones blood pressure. They do this by blocking signals from ones brain to nervous system that speed up ones heart rate and narrow veins and arteries.Mode of action-Central sympatholytic drugs reduces blood pressure mainly by stimulating central a2-adrenergic receptors in the brainstem centres, thereby reducing sympathetic - [Calcium Channel Blockers or Calcium Antagonists](https://www.elearning.dlife.in/lds-course-notes/calcium-channel-blockers-or-calcium-antagonists-9/) - Notes:Calcium channel blockers or calcium antagonists are a group of medications that disrupt the movement of calcium thru calcium channels . Calcium blockers are used as antihypertensive drugs.e. as medications to decrease blood pressure in patients with hypertension. Calcium channel blockers are also called calcium antagonists.Mode of Action - Calcium Antagonists are group of medicines - [Current Treatment Options For NAFL and NASH](https://www.elearning.dlife.in/lds-course-notes/current-treatment-options-for-nafl-and-nash-9/) - current treatment options for NAFL and NASH - diet and lifestyle modification - wt looss, physical activity, sugar/fructose no, low carb/ketosupplements - turmeric, coffe, omega-3 fatty acids, Vit E, N-acetyleCysteine (NAC) - resulted in decreases in serum alanine aminotransferse, selenium - may help in preventing fibrosismeds - Pioglitazone (NAFLD + T2D), GLP-1 receptor antagonists - [Liver Disease – Causes Symptoms Diagnosis & Prevention](https://www.elearning.dlife.in/lds-course-notes/liver-disease-causes-symptoms-diagnosis-prevention-9/) - Liver disease - causes symptoms diagnosis & prevention - risk factors - obesity, high BP, abnormal cholesterol levels, IR, alcohol, T2D, tattoes/body piercing, blood transfusion before 1992, exposure to other people's blood and body fluids, unprotected sex, exposure to certain chemicals or toxins, family historyNASH - IR is imp triggercauses - infection (parasites, viruses) > inflammation - [NAFLD – The Progression Details](https://www.elearning.dlife.in/lds-course-notes/nafld-the-progression-details-11/) - NAFLD - the progression details - fatty liver diseases - what is fatty liver - more than 5% of your organ weight normal - nice evenly sized pink cellsfatty liver - more than 5% of liver has fat in itmost common cause - alcohol2nd most common cause - NAFLDother - medicines - hep. B, autoimmune diseaseisolated fast or - [Non Alcoholic Fatty Liver Disease – NAFLD](https://www.elearning.dlife.in/lds-course-notes/non-alcoholic-fatty-liver-disease-nafld-11/) - Non alcoholic fatty liver disease - NAFLD - human adult liver - weighs about 1.4 kg (3.1 pounds) - found in upper right abdomen - below diaphragm.takes up most of the space under ribs and some open space in left upper abdomen toogallbladder -bile is stored here - small hollow on the underside of liver.anatomy of - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-61/) - Notes:atherosclerosis: thickening othe walls of arteries. - [Insulin Resistance & Hypothyroidism](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-hypothyroidism-20/) - Hyperthyroidism primarily causes hepatic IR, whereas hypothyroidism seems to cause IR in peripheral tissues. Both the conditions can lead to poor BG control.Hyperthyroidism speeds up the body's metabolism and causes symptoms like weight loss, a rapid heartbeat, sleep problems, and anxiety/nervousness. The most common cause is Graves' disease, an autoimmune disorder, but other causes include - [Insulin Resistance & Hypertension](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-hypertension-22/) - Insulin resistance / hyperinsulinemia is closely linked to hypertension through several mechanisms.It can increase SNS activity, leading to a higher heart rate and blood pressure.While insulin's effect on glucose uptake is diminished, its effect on salt reabsorption in the kidney tubules can be preserved or even enhanced, leading to high sodium and blood volume contributing - [Beta Blockers](https://www.elearning.dlife.in/lds-course-notes/beta-blockers-9/) - Notes:Beta Blockers reduce Blood Pressure.Mode of Action - Work by blocking the effects of hormone epinephrine. Beta blockers makes ones heart beat slowly and with less force.Other benefits :-Angina, Cardiac healing after a attack, heart failure, Heart rhythm problems such as atrial fibrillation or palpitations.Hyper trophic cardiomyopathy, Anxiety , Essential tremor, glaucoma.Side effects -Dizziness, weakness, - [Angiotensin II Receptor Blockers](https://www.elearning.dlife.in/lds-course-notes/angiotensin-ii-receptor-blockers-8/) - Notes:Angiotensin II receptor blockers also known as Angiotensin II receptor antagonists AT are group of Pharmas that modulate the renin -angiotensin system. Main use are in Hypertension, diabetic nephropathy and congestive heart failure.Mode of action - Angiotensin II receptors blockers are medications that block the action of angiotensin II by preventing binding to angiotensin II - [Alpha Blockers](https://www.elearning.dlife.in/lds-course-notes/alpha-blockers-9/) - Notes:Alpha Blockers also known as A blockers are a class of pharmaceutical agents that act as antagonists on a-adrenergic receptors. Historically, alpha -blockers were used as a tool for pharmacologic research to develop a greater understanding of the autonomic nervous system. They are used for hypertension in some patients.Mode of action - Alpha blockers work - [Angiotensin Converting Enzyme Inhibitors](https://www.elearning.dlife.in/lds-course-notes/angiotensin-converting-enzyme-inhibitors-9/) - Notes:Angiotensin - used for treatment of high blood pressure and heart failure.Mode of Action -They work by relaxing blood vessels as well as decrease in blood volume.These medications slow the activity of enzyme ACE, which decreases the production of angiotensin II As a result blood vessels enlarge or dilate and BP is reduced.Other benefits - - [Hypertension Medications](https://www.elearning.dlife.in/lds-course-notes/hypertension-medications-5/) - Anti Hypertensive medications are those Pharma drugs that reduce blood pressure in the case of those who have elevated levels. Blood pressure is the pressure of circulating blood on the walls of blood vessels. Most of this pressure is due to work done by the hearty pumping blood through the circulatory system.Blood pressure usually refers - [Weight Loss Medications](https://www.elearning.dlife.in/lds-course-notes/weight-loss-medications-9/) - Notes:Obesity is serious medical condition that leads to high blood pressure, high cholesterol and heart disease. Loss of sleep, consumption of junk food, physical inactiveness are major causes of obesity. According to the World Health Organization, around 13% of the worlds population is characterised as obese.High costs, weight regain after obesity treatments are major hindrances - [Sulfonylureas and Meglitinides](https://www.elearning.dlife.in/lds-course-notes/sulfonylureas-and-meglitinides-9/) - Notes:Moe of Action - Act by stimulating the pancreas to produce more insulin. They bind to an ATP dependent K + channel on the cell membrane of pancreatic beta cells. The Glinides differ from the Sis in their reduced affinity to the receptors, thus binding for a shorter duration, resulting in shorter action of the - [Thiazolidinediones](https://www.elearning.dlife.in/lds-course-notes/thiazolidinediones-9/) - Notes:TZDs decrease insulin resistance by the formation of new fat cells, primarily on arms, thighs and butt, activates a number of genes in the body which play a role in glucose metabolism and the manner in which the body stores fat.Other benefits - Helps preserve the function of insulin producing cells. It can also increase - [GLP1 Analogues](https://www.elearning.dlife.in/lds-course-notes/glp1-analogues-9/) - Notes:Glucagon like peptide 1 receptor agonists also known as GLP 1 receptor agonists or incretin mimetic are agonists of the GLP 1 receptor . This class of medications is used for the treatments of type 2 diabetes.Mode of action :-They work by copying or mimicking the functions of the natural incretin hormones in ones body - [Folate](https://www.elearning.dlife.in/lds-course-notes/folate-20/) - Notes: - [PCOS & Obesity – The Connection](https://www.elearning.dlife.in/lds-course-notes/pcos-obesity-the-connection-10/) - PCOS and obesity - the connection - IR, hyperinsulinemia, lower SHBG, obesityinsulin decreases levels of SHBG , decreases IGFBP-1 production, upregulates ovarian IGF receptor type 1 with amplification of IGF-1, IGF-2 and insulin actions in ovary, increases LH ovary receptor number and sensitizes LH secreting pituitary cells to GnRH stimulation, promotes ovarian growth and cyst formations, - [PCOS – Medical Approach For Treatment](https://www.elearning.dlife.in/lds-course-notes/pcos-medical-approach-for-treatment-10/) - PCOS - medical approach for treatment - IR, T2D, high cholesterol, high BP, heart disease etc.tests - physical exam - BP, BMI, waist size. check skin for extra hair on face, chest, back, acne, skin discoloration, hair loss, enlarged thyroid glandpelvic exam - for signs of extra male hormones - ex. enlarged clitoris, check if ovaries are - [PCOS — Causes & Symptoms](https://www.elearning.dlife.in/lds-course-notes/pcos-causes-symptoms-12/) - PCOS - causes and symptoms - causes - genes, IR, inflammation - excess androgen productionPCOS runs in families, extra insulin triggers ovaries to produce more androgens - obesity, IR, excess inflammation > higher androgen levelssymptoms - irregular menses, pelsvin pain, multiple small cysts in ovaries, acne, wt gain, heavy bleeding, headaches, infertility, elevated BP, hair growth - [PCOS – Gynecological Or Metabolic Problem?](https://www.elearning.dlife.in/lds-course-notes/pcos-gynecological-or-metabolic-problem-11/) - PCOS - gynecological or metabolic problem?misdiagnosed as gynecological condiiton - usually treated with birth control pills by gynec and for a long term - manage estrogen and progestinbut it is metabolic, hormonal and psychosocial disorder - they have emotional stresshyperinsulinemia is the culprit - 70% PCOS is coz of thatprecursor of estrogen is androgen (testosterone - [PCOS – Polycystic Ovarian Syndrome](https://www.elearning.dlife.in/lds-course-notes/pcos-polycystic-ovarian-syndrome-18/) - PCOS - PCOS and IR - obesity, T2Dobese women - 75% - IR first reported by Stein, Leventhal in 1935 - symptoms with complex amenorrhea, hirsutism, enlarged ovaries with multiple cystsprevalence - 2.2 - 26% globally. 2-7.5% in China, 6.3% in Srilanka. south India - 9.13%, Maharashtra 0 22.5% US - 5- 10% of women between 15 and 44 - [Heart Failure](https://www.elearning.dlife.in/lds-course-notes/heart-failure-9/) - heart failure - heart does not pump well as it shouldcoronary artery disease, diabetes, hypertension, cardio-renal syndromeIR > structural abnormalities in heart like increases left arterial size, left ventricular masstypes: 1. with reduced left ventricular function (HF-rEF) - left ventricle > bigger in size> cannot pump enough amount of oxygen-rich blood to rest of body2. with - [Heart Attack](https://www.elearning.dlife.in/lds-course-notes/heart-attack-11/) - Types of heart attack - 1. ST-segment elevation myocardial infarction (STEMI) - requires immediate attention. coronary artery is fully blocked - immediate revascularization or angioplasty2. Non-ST segment elevation myocardial infarction (NSTEMI) - less damage to patients heart. troponin protein in blood - when heart muscle is damaged - angioplasty, cardiac bypass graft surgery3. coronary artery spasm - [Hypertension](https://www.elearning.dlife.in/lds-course-notes/hypertension-7/) - hypertension - white coat HTN - outside Dr. office, normal BP, inside office - high BP - ambulatory BP monitordecreased salt ecretionhigh sodium, high renin or hyperactive SNS - [Cardiac Arrhythmia](https://www.elearning.dlife.in/lds-course-notes/cardiac-arrhythmia-11/) - cardiac arrhythmias - sinus - normal - 60-100 bpm,sinus braduycardia - < 60 bpm - normal in sleepsinus tachycardia - > 100 bpm - normal inn exerciseatrial flutter - right atrium types - 1. tachycardia - fast heart rhythm > 100 bom2. beadycardia - slow heart rate < 60 bpm3. supraventricular arrhythmias - arrhythmias that begins in - [Cardiomyopathy](https://www.elearning.dlife.in/lds-course-notes/cardiomyopathy-11/) - Cardiomyopathy - heart, muscle - disease - right heart >? takes blood from body > pumpsblood oxygenated in lungs and given to left heartdisease of heart muscle - causes pump to fail - right heat > lungs or left heart > body - this is a problem in this diseasenot enough blood to lungs - shortness - [Atherosclerosis](https://www.elearning.dlife.in/lds-course-notes/atherosclerosis-12/) - Atherosclerosis - cause build up of fatty substance - plaque.in arteries - fatty plaque - yellow stuff1. some irritants in blood - fats - LDL cholesterol, toxins from cigar, hypertension2. damage to endothelials3. cholesterol will start collecting under damaged endothelial - fatty streak once cholesterol goes into endothelial - macrophase - starts eating it > called - [Notes Taking Explained](https://www.elearning.dlife.in/lds-course-notes/notes-taking-explained-27/) - Notes: test notes - [Cardiovascular Disease – CVD](https://www.elearning.dlife.in/lds-course-notes/cardiovascular-disease-cvd-13/) - cardiovascular disease - CVDanatomy of heart - seq of blood flow from lung to heart - left and right pulmonary vein > left atrium > mitral valve (bicuspid valve) > left ventricle > aortic valve - thickness of garden hose > bodysuperior VC, Inferior VCSVC > RA > Tricuspid valve - preventing blood flow from - [Exogenous Insulin](https://www.elearning.dlife.in/lds-course-notes/exogenous-insulin-8/) - Notes:Basal or Long Acting Insulin- Correct dosage of basal insulin to keep ones blood sugar level even when not eating will make life easier as one doesn't have have to worry about skipping meals or delay in meals. It is cloudy insulin, roll between hands 20 times before use. made by adding protamine to a molecule - [Sodium-Glucose Cotransporter-2 – SGLT2 – Inhibitors](https://www.elearning.dlife.in/lds-course-notes/sodium-glucose-cotransporter-2-sglt2-inhibitors-9/) - Notes:Sodium Glucose Cotransporter2 Inhibitors have been used in type 2 diabetes treatment since 2013.Mode of action - SGLT-2 inhibitors are a novel class of anti diabetic agents that act by inhibiting glucose reabsorption in proximal convoluted tubules of the kidney.Apart from maintaining glucose homeostasis they exert positive effects on the cardiovascular system like weight loss, - [Dipeptidyl peptidase-4 – DPP4 – Inhibitors](https://www.elearning.dlife.in/lds-course-notes/dipeptidyl-peptidase-4-dpp4-inhibitors-9/) - Notes:DPP4 are a class of medicine that lower high blood glucose levels may be used in treatment of type 2 diabetes.DPP4 inhibitors lows inactivation and degradation of GLP -1 a hormone involved in glucose removal from the gut.Mode of action -It surpasses the enzyme that breaks down the incretin hormones, resulting in prolonged action of - [Biguanides](https://www.elearning.dlife.in/lds-course-notes/biguanides-9/) - Notes:Oral Type 2 drugs, works by preventing the production of glucose in the live, improving body sensitivity to insulin and reducing the amount of sugar absorbed by the intestines. Biguanides are usually supplied as polymers in the salt form mostly as hydrochloride.Mode of action -1.It reduces liver dump of glucose , conversion of glycogen into - [Alpha Glucosidase Inhibitors](https://www.elearning.dlife.in/lds-course-notes/alpha-glucosidase-inhibitors-10/) - Notes: FDA approvals Acarbose in 1995. Miglitol in 1999. Voglibose recently.Slows down the digestion and absorption of Carbs by blowing the enzyme, alpha -glucosidase, which helps in digesting carbs in small intestine. This slowing down of absorption causes the blood sugar level to peak less after carb reach meal therefore aids in better blood sugar control.Benefits - [Diabetes Medications](https://www.elearning.dlife.in/lds-course-notes/diabetes-medications-3/) - Notes:Diabetic Medication types :-1.Oral Pills 2.Exogenous Insulin Oral pills for blood sugar management, classified in six groups :-1.Alpha Glucosidase Inhibitors2.Biguanides3.Dipeptidyl peptidase 4 DPP4 - Inhibitors4. Sodium Glucose Cotransporter -2 - SGLT2 - Inhibitors5.Sulfonylureas and Meglitinides6. Thiazolidinediones While switching to LCHF we have to be careful that client talks to doctor for correction in dose. - [Diabetes Diagnosis & Management](https://www.elearning.dlife.in/lds-course-notes/diabetes-diagnosis-management-9/) - diabetes diagnosis and management - tests for type 1, type 2 - A1C - measures % of sugar attached to Hb (oxygen carrying protein) in RBC. 5.6 - 6.4 prediabetic, below is normalrandom blood sugar test - level of 200 miligrams per deciliter or higher - suggests diabetesfasting blood sugar test - < 100 mg/dL is normal - [Diabetic Complications](https://www.elearning.dlife.in/lds-course-notes/diabetic-complications-12/) - diabetic complications - microvascularneuropathy, nephropathy, retinopathy, CVD, ketoacidosis, hypoglycemiaoverproduction of reactive oxygen species (ROS), CNS effects, also cause gastroparesis, diabetic nephropathy - end stage renal diseasemacrovascular - measuring biomarkers of atherosclerosis > helpful in detecting macrovascular complications of diabetes.misc - chronic ulcers fail to heal. statins - negatively affect glycemic control in diabetes patients. postprandial dyslipidemia - - [Gestational Diabetes](https://www.elearning.dlife.in/lds-course-notes/gestational-diabetes-11/) - Gestational diabetes - - [Type 2 Diabetes](https://www.elearning.dlife.in/lds-course-notes/type-2-diabetes-9/) - Type 2 Diabetes - body does not make enough insulin or doesn't use it well. classification - type n2 type 2 MODY - developed in adolescence or early adulthood - maturity onset diabetes of the young. about 5% of all diabetes cases in US. high blood glucose levels damage eyes, kidneys, nerves, blood vessels. MODY can show up - [Type 1 Diabetes](https://www.elearning.dlife.in/lds-course-notes/type-1-diabetes-13/) - Type 1 diabetes - body's immune sys attacks pancreatic cells that make insulin - no insulin. people need to take insulin everyday to stay aliveclassification - juvenile or T1D - in children - no insulin - need injections or pump. no cure but can be managed. latent type 1 in adults or typ1 1.5 diabetes - subtyoe - [Diabetes](https://www.elearning.dlife.in/lds-course-notes/diabetes-14/) - Diabetes - A1C - hb is a protein in RBC - avg RBC lives about 120 dayshigher blood glucose - will stick to hb - glycated hb/sugar - thats why 3 month avgdamages RBCs - check any time of day. check once a year if normal/healthy else every 3-6 monthsany number above 5.6 is terribleblood sugar regulation - [TOFI – Thin Outside Fat Inside – Obesity](https://www.elearning.dlife.in/lds-course-notes/tofi-thin-outside-fat-inside-obesity-12/) - TOFI - thin outside fat inside - obesity - in and around liver, pancreas. - visceral fat - fat is exceeding and thats why getting stored herechornic hyperinsulinemia fat cells - adipocytes are full - resisting firther fat storageBMI - useless - does not tell u your body compositionnormal weight obesity - normal BMI but overfat - - [Obesity & Hypertension](https://www.elearning.dlife.in/lds-course-notes/obesity-hypertension-10/) - obesity and hypertension = genetic component but imp cause if obesity for hypertension1. carrying more CO, enlargement of organs - more blood flow there2. high sympathetic nervous sys activity - inflammatory cells can be cause > increased vasacl constriction3. increased release of angiotensin 2 > causes vasal constrictions of renal micro-vessels - impaired kidney functions, aldosterone - [Obesity & Diabetes](https://www.elearning.dlife.in/lds-course-notes/obesity-diabetes-13/) - Obesity and diabetes - not just amount of fat but where is it located matters tooAlso because of bad fat metabolismBMI - strong relationship with IR, diabetes. obese individuals - amnt of nonesterified fatty acids, glycerl, hormones, cytokines, pro-inflammatory markers > development of IRin US, 2/3rd of adult population - overwt/obese - [Obesity & Cardiovascular Disease](https://www.elearning.dlife.in/lds-course-notes/obesity-cardiovascular-disease-12/) - Obesity and CVD risk - association between obesity, hypertension, diabetes mellitus, dislipidemia, sleep apnoea - increased incidents of cardiovacular disordersObesity > affect hemodynamics, alter Is heart structureLipids, oxidized LDL particles, free fatty acid > inflammation increases > CVD riskAt least 2 decades of obesity > coronary artey disease. 10 kg excess body wt > 12% - [Obesity & Autoimmune Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-autoimmune-disorder-10/) - Obesity and autoimmune diseaseConplex pathway of these disorders are regulated by diff cytokines - IL-6 very imp - involved in inflamamtion, immunoregulation, hrmatopoeisisLeptin adiponectin, resiston, vistafin, Involvement of adipokines in pathogenesis of autoimmune disease - [The Role of Sleep](https://www.elearning.dlife.in/lds-course-notes/the-role-of-sleep-9/) - Notes:Sleep plays a vital role in good health and well being through out the span of life. Our internal body clock that controls when we are awake and when our body is ready for sleep . The body clock typically has 24 hrs repeating rhythm called as circadian rhythm. Two processes interact to control this - [Insulin Resistance, Lipotoxicity & Energy Toxicity](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-lipotoxicity-energy-toxicity-7/) - IR, lipotoxicity & energy toxicity - energy toxicity - why a cell becomes IRgenerally focused on muscle, liver, cell loaded with energy > becomes resistant to store more energylipotoxicity - energy toxicity - fat stored is the cause - excess storage of lipidscan apply to both glucose, fatsfat or glucose - what is causing bigger size - [Adipose Tissue](https://www.elearning.dlife.in/lds-course-notes/adipose-tissue-17/) - Adipose tissue - lipid-storing type of loose connective tissue. adipose cells/adipocytesliver (anything metabolic) , white adipose tissue (WAT), brown adipose tissue (BAT), insulin, ketone (metabolite)WAT - storing energyBAT - thermoregulation - create heat - uses energybabies - lot of BAT - don't shiver after shower, but adults - shiver - to create heat (less BAT, more - [Fructose](https://www.elearning.dlife.in/lds-course-notes/fructose-9/) - Notes:Most of the fructose is absorbed by facilitated transport in the jejunum by Glut 5. The body has limited capacity to absorb pure fructose and intake of fructose can lead to malabsorption.Fructose Metabolism -Fructose's best understood by considering three enzymes : fructose kinase, fructose -bisphosphate, aldolase B and adenosine triphosphate .Hence, fructose is entirely processed - [Metabolic Disorder — Current Indian Data](https://www.elearning.dlife.in/lds-course-notes/metabolic-disorder-current-indian-data-7/) - metabolic disorder - current Indian data - obesity, diabetes, IR, hypertension, PCOSobesity - 40% adults - central obesity - 20-25% adults - this form associated with diabetes, hypertension, CVD - sedentary lifestylem high-calorie diet, genetic predispositionsprevalence of obesity - 28%, abdominal obesity - 39%diabetes - prevalence of diabetes - 11.4% adults, prediabetes - 15.3%IR - 15-35% - [LIPID Peroxidation & Neurological Disorders](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-neurological-disorders-9/) - LIP & neurological disorders - high O2 consumption, abundant PUFA, relatively low antioxidant defenses - vulnerable to oxidative damageAlzheimer;s - high levels of HNE in AD - aggregation of beta - amyloid plaques > synaptic dysfunction, neuroinflammation, neuronal apoptosis > cognitive declineParkinsons' - oxidative damage to dopaminergic neurons in substantia nigra is a hallmark of PD - [Luteinizing Hormone](https://www.elearning.dlife.in/lds-course-notes/luteinizing-hormone-14/) - Notes:Lh suge day 14,ovulation is triggered by drop in lh surgelh surge 16 to 104 on 14th day.leuyinised un ruptured follicular syndrome.35to44 hours after Lh surge begins ovulation occurs.lh low during pregnancy.Spotting higher progesterone, and age 30 - [LIPID Peroxidation & Diabetes](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-diabetes-9/) - Lipid peroxidation & diabetes - There is considerable evidence that hyperglycemia represents the main cause of complications of diabetes mellitus (DM), and oxidative stress resulting from increased generation of reactive oxygen species plays a crucial role in their pathogenesis. In fact, in the absence of an appropriate response from endogenous antioxidant mechanisms, the redox imbalance causes - [LIPID Peroxidation & Cardiovascular Disease (CVD)](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-cardiovascular-disease-cvd-10/) - omega-6 seed oils - corn, canola, cottonseed, sesame, peanut, soybeanhighly oxidized oilsleast stable - oxidation productions during cooking like lipid peroxides and aldehydes sunflower, canola, grapeseed - worstoxidation products - absorbed in intestine - oxidize cells there > chronic diseasesLDL + omega-6 > oxidation > oxidized LDL > chemotactic, cytotoxicreduce dietary intake of linoleic acid - - [LIPID Peroxidation](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-11/) - LIPID Peroxidation -complex process > oxidative degradation of lipids - PUFA. contributes to cellular damage and rancidity in fatsmechanism - 3 steps1. initiation - free radicals like hydroxyl radicals (OH), abstract H2 atoms from C-H binds in lipids. allylic positions of PUFAs. leading to formation of lipid radicalslipid + .OH > L. + H2OLipid + - [Non Alcoholic Fatty Liver Disease – NAFLD](https://www.elearning.dlife.in/lds-course-notes/non-alcoholic-fatty-liver-disease-nafld-10/) - Notes:The liver is vital organ of the body for overall homeostasis thru several biochemical processes and without these functions life cannot be maintained. The human adult liver weighs about 1.4 kg ( 3.1 Pound)and is found in right upper abdomen, below the diaphragm. It takes up most of the space under the ribs and some - [Test And Numbers & CAC Score](https://www.elearning.dlife.in/lds-course-notes/test-and-numbers-cac-score-15/) - Test and numbers & CAC score - lipid profile/panel test - for cholesterolcalled as coronary risk panel, lipid profile, fasting lipid profile, non-fasting lipid profile, cholesterol panel, lipid testto assess risk of CVD, to monitor unhealthy lipid levels.screening - when no risk is present - every 4-6 years, for children, teens, young adults, once between 9 - [Background And Current Status](https://www.elearning.dlife.in/lds-course-notes/background-and-current-status-9/) - background and current status - except for hyper responders, dietary cholesterol has lil relation with serum cholesterol1 large egg = 186 mg of cholesterol. dietary recomm - limit 300 mg/day - but since there is no relation between dietary and serum cholesterol, u can still eat 4-8 eggs and cholesterol does not go updietary cholesterol hyper responders - [Cholesterol & Its Functions](https://www.elearning.dlife.in/lds-course-notes/cholesterol-its-functions-16/) - Cholesterol & its functions - Cholesterol - C27H46O organic compound - as a building block for cell membranes, for hormones like estrogen, testosterone. most waxy substance made by liver, rest comes from dietary sources like meat, poultry, eggs, fish, diary productsfood from plants - no CholesterolCholesterol content in blood is regulated by liver.Cholesterol - essential for all animal - [High Intensity Interval Training – HIIT](https://www.elearning.dlife.in/lds-course-notes/high-intensity-interval-training-hiit-8/) - HIIT - interval training is separate from HIIT2-3 sessions a week - perfectincrease heart rate to at least 80% of one's max heart rate > followed by short periods of lower intensity movement15 sec to 4 mins - followed by recovery intervalswork to rest ratio - 2:1 ex. 30 sec of intense exercise followed by 12 - [Bent Over Row](https://www.elearning.dlife.in/lds-course-notes/bent-over-row-3/) - bent over row - entire back muscles, trapezius muscles, rhomboids, last, forearms, biceps - [Dead Lift](https://www.elearning.dlife.in/lds-course-notes/dead-lift-4/) - deadlifts - hamstrings, glutes, lower back muscles, trapezius muscles, rhomboids, lattismus dorsi. - [Pull Exercise](https://www.elearning.dlife.in/lds-course-notes/pull-exercise-4/) - cardio - cardiorespiratory - for improved endurancewt training - resistance training - training skeletal muscles - making them stringer and hypertrophied - push and pull exercisespull - back muscles, biceps, hamstrings, obliques, trapezius.less time consuming, creates muscle balance, promotes injury prevention, increases muscle mass in all muscle groups - [Push Exercise](https://www.elearning.dlife.in/lds-course-notes/push-exercise-3/) - push exercise:day 1 - pushsquats - 3*12lunges - 3*15bench press - 3*15 bench - 3*15tricep variation 1 - 3*15tricep variation 2 - 3*15day 2 - cardioday 3 - pullpull ups - warm updeadlifts - 3*12bent over rows - 3*15lat pulldown - 3*15bicep variation 1 - 3*15bicep variation 2 - 3*15day 4 - restday 5 - pushbench - [Bench Press](https://www.elearning.dlife.in/lds-course-notes/bench-press-4/) - bench press, squat, deadlift - trinity for strength building compound exer - [Anabolic Resistance](https://www.elearning.dlife.in/lds-course-notes/anabolic-resistance-10/) - Anabolic Resistance - anabolic stimuli - amino acids, proteinsphenomenon of agingdecline in muscle mass and fucntion over timelosing muscle mass due to age - due to anabolic resistance.physical function, independence of livingfalling, fracturesskeletal muscle - glucose metabolism, IR muscle - glucose sync/consumer - ability to correct blood glucose - 'muscle mass - greater quality of life in - [Excess Post-exercise Oxygen Consumption (EPOC)](https://www.elearning.dlife.in/lds-course-notes/excess-post-exercise-oxygen-consumption-epoc-8/) - excess post exercise oxygen consumption - EPOCbody keeps burning more calories post workout when at rest - called excess post exercise oxygen consumptionEPOC - amount of oxygen req to restore your body to its normal, resting level of metabolic function (homeostasis).this has significant implications for fitness, metabolism, recoveryEPOC - body's resp to exercise, - req - [Muscle Gain](https://www.elearning.dlife.in/lds-course-notes/muscle-gain-11/) - muscle gain: macronutrient targets - min 75% gm of protein per daycarbs max 30 gmmuscle gain:males - within IBW range - if lean, muscular - cuurent wt *intensity, if carries fat - LBM * intensity take body fat *%) = 15%females - within IBW range - hypertrophy in female will not be same as male. so use - [Weight Loss](https://www.elearning.dlife.in/lds-course-notes/weight-loss-11/) - wt loss - 1 to 0.75 gm of fat - per 1 gm proteinwt stall - if not losing wt - suggestion is to lower fat, increase first-class protein - for every 5g fat - replace with 10 g of protein OR spend more time in gym - more weights etc - but again here u - [Diet And Supplement Planning Goals](https://www.elearning.dlife.in/lds-course-notes/diet-and-supplement-planning-goals-13/) - Diet and supplement planning goals - B-complex Vit - 12-200 mcg/day. essential for athletic perfVit E - prevent breakdown of muscle, hair, skinVit C - fights free radicals, body defense and immunity - in cough, cold esp. - also helps recycle Vit E and glutathioneMagnesium - crucial for Ca absorption. bed time best time - 500 - [The Randle Cycle: Understanding the Glucose-Fatty Acid Cycle](https://www.elearning.dlife.in/lds-course-notes/the-randle-cycle-understanding-the-glucose-fatty-acid-cycle-9/) - Randle cycle - understanding glucose fatty acid cycle - Philip Randle - cambrige - 1960fatty acid - from free fatty acids (from fat tissue) or triglycerides like LDL, VLDLoxidation - fat burnt for producing ATP - acetyl-CoA, NADH - inhibit pyruvate dehydrogenase - no glucose breakdown hencealso produces citrate - comes out of mitochondria - inhibit - [Three States Of Ketosis](https://www.elearning.dlife.in/lds-course-notes/three-states-of-ketosis-16/) - 3 states of ketosis - ketogenesis the metabolic pathway - produces ketone bodies, alt form of energy. body constantly produces ketone bodies - each 22 ATP in normal circumstances, regulated by insulin. ketosis - increases ketone bodies in low carb, high fat/fatty acid diet. however - ketoacidosis - too many ketone bodies accumulate in case of uncontrolled diabetesfatty - [Aerobic Energy System](https://www.elearning.dlife.in/lds-course-notes/aerobic-energy-system-18/) - Aerobic energy system - AES - in presence of oxygen - produces large amount of energy/ATPATP production in aerobic pathway - 1 glucose mol - 32-38 ATP1 fatty acid - 18 carbons - 129-147 ATP1 triglyceride wich is 3 fatty acids + 1 glycerol - 460 ATPaerobic pathway for glucose - in mitochondria. aerobic - uses oxygen and - [Krebs Cycle](https://www.elearning.dlife.in/lds-course-notes/krebs-cycle-18/) - Krebs cycle - citric acid cycle/ tricarboxylic acid cyclepart of cellular respirationglycolysis - 2 pyruvate mol - each 3 carbon atoms - in absence of oxygen+ 2 ATP, 2 NADHglycolysis - in cytoplasmkrebs - inner space of mitochondriaouter compartment, inner compartment is called matrixprep step for krebs cycle - oxidation of pyruvate > 2 carbon - [Lactic Acid Energy System](https://www.elearning.dlife.in/lds-course-notes/lactic-acid-energy-system-15/) - Lactic acid energy system - glycolysis - process of breaking down glucoseanaerobic glycolysis - 10 step processoccurs in cytoplasm. mol of glucose - one 6-carbon mol - is oxidized step by stepend product -> 2 molecules of pyruvate ( each 3-carbon), 2 mol of ATP, 2 mol of NADH, 2 mol of water1. phosphorylation suing enzyme - [ATP-PC Energy System](https://www.elearning.dlife.in/lds-course-notes/atp-pc-energy-system-16/) - ATP-PC energy system - alactic sys, phosphocreatine, creatine phosphate, phosphagenfuel source - phosphocreatineintensity of activity - very high - >95% max heart rateduration sys is dominant - 1-5 secondspeak power - 2-4 secondsamnt of ATP produced - 0.7 ATP/PC moleculespeed of production - instantaneousby-products - inorganic phosphate (Pi), ADPlactic acid energy sys - anaerobic sys fuel - [Adenosine Triphosphate – ATP](https://www.elearning.dlife.in/lds-course-notes/adenosine-triphosphate-atp-19/) - ATP - Adenosine Triphosphate - adenine base - attached to ribose sugar - which is attached to 3 phosphate groups. these 3 phosphate groups are linked to each other by 2 high-energy bonds called phsophoanhydride bindshow ATP produces energy - energy produced by breaking phosphate bond - exothermic reaction - when ATP loses 1 or more phosphate groups - [Energy Pathways](https://www.elearning.dlife.in/lds-course-notes/energy-pathways-20/) - Energy pathways - 1 kilocalorie - 4.2 kilojoulesmetabolism - combination of1. catabolism - process of breaking complex compounds2. anabolism - process of building up of compoundsum of all chemical reactions in living organism.catabolism - destructive metabolism - series of enzyme catalyzed reactions. small units generated > oxidized to produce energy or used in anabolic reactionsex. cellular - [Inflammation](https://www.elearning.dlife.in/lds-course-notes/inflammation-22/) - Inflammation - immune sys response to recognize and respond to infection, injury.too less response - prone to infectiontoo much of a response > chronic injury like heart diseases, T2D, common cancers, Alzehimer'sbalance between 2 - depends on diet, env factors, genetic inheritancehigh levels of WBC and c-reactive protein (CRP), hsCRP - predict development of tT2D, cancersWBC- - [AMPK Pathway](https://www.elearning.dlife.in/lds-course-notes/ampk-pathway-20/) - AMPK pathway - insulin - glucagon - antagonists of each othermTOR - AMOK (Adenosine Monophosphate activated Protein Kinase) - opposing pathways- role as regulator of both lipid and glucose metabolism - potential therapeutic treatment for T2D, cancer, obesitymaster regulator of cellular energy homeostasisheterotrimeric complex - catalytic alpha subunit & regulatory beta and gamma subunitbinding of AMP - [mTOR Pathway](https://www.elearning.dlife.in/lds-course-notes/mtor-pathway-26/) - mTOR pathway - mammalian target of rapamycin- part of complex network of cell signaling and transductionpart of phosphatidylinositol 3-kinase (PI3K) pathway - family of lipid kinases involved in cell growth, proliferation, survival. mTOR nucleates at least 2 multi-protein complexes - mTOR complex 1 - mTORC1, mTOR complex 2 mTORC2controls cell functions - cell growth, autophagy (lysosomal - [Dehydration & Sodium Importance in Sports](https://www.elearning.dlife.in/lds-course-notes/dehydration-sodium-importance-in-sports-19/) - Dehydration & sodium impotsance in sports - water is necessary - not sugary drinks - they don't provide necessary mineralslow carb diets & hydration - himalayan - has iodine, sea-salts we get here does notwhen salt intake is cut - adrenaline, aldosterone all stress hormones increase - hypertension is caused, CVD issues, fatigue, dizzy, light headed - - [Importance of Hydration](https://www.elearning.dlife.in/lds-course-notes/importance-of-hydration-12/) - Importance of hydration - avg 60% body in adult men - this decreases with lean body massorgans - more than 70% waterblood, kidney - 83$ watermuscles - 76% wateradipose tissue - only 10% water2/3rd body water - intracellularextracellular - plasma and intestinal fluidsingested water - mainly absorbed in SI - appears in blood in 5 mins - [Insulin Resistance & PCOS](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-pcos-23/) - PolyCystic Ovarian Syndrome (PCOS) is the most common hormonal disorder (endocrine condition) in women during their reproductive years (9-26% prevalence in India). It is recognized as an important metabolic as well as reproductive disorder which substantially increases risk for T2D.Symptoms and diagnosisHyperandrogenism - excess male hormones circulating, main one being testosterone, which is produced by - [Water & Electrolytes](https://www.elearning.dlife.in/lds-course-notes/water-electrolytes-17/) - Water and electrolytes - https://pmc.ncbi.nlm.nih.gov/articles/PMC3951800/https://www.ncbi.nlm.nih.gov/books/NBK537088/we can survive upto several weeks without food, but only few days without water. every cell, tissue, vital organ - needs waterwater functions - 1. hydration - prevents headaches, fatigue, dry skin. 2. protection - brain, blood, bones benefit from water. joints like knees, ankles, elbows - kept lubricated and cushioned by water, also - [Importance Of Protein & Fat In Sports](https://www.elearning.dlife.in/lds-course-notes/importance-of-protein-fat-in-sports-10/) - Importance of protein and fat in sports - proteins, fats - essential macronutrientsbody tried to clear alcohol and glucose first because they both are toxic for the bodyapart from energy, cell membrane is made up of fats. testosterone - hormone needed for muscle building and muscle protein synthesis is made from fats. every cell, tissue, hormone and - [Three Pillars Of Fitness](https://www.elearning.dlife.in/lds-course-notes/three-pillars-of-fitness-14/) - 3 pillars of fitness - sleep - very imp - sleep deprived, gain wt.5-10 pounds by sleeping bettergo to bed same time every nightset alarm for going to beddim lights, lil bit noise/white noise - helps u not think, smell makes u relax like lavender, touch - mattress, pillow, more comfortable - more muscle relaxationconsistent bedtime, - [Introduction To Sports Nutrition](https://www.elearning.dlife.in/lds-course-notes/introduction-to-sports-nutrition-16/) - Introduction to sport nutrition:glycogen stores are finite - so cannot have more carbs for high intensity exercises - if excess, will be stored as fatketo/LCHF - more sodium lost in urine - atkins flulow carb people - better oxidation/burning of fat per minutesports nutrition/performance based nutrition - study and practice of hydrating and fueling your - [20 Common Mistakes On LCHF / Keto Diet](https://www.elearning.dlife.in/lds-course-notes/20-common-mistakes-on-lchf-keto-diet-15/) - 20 common mistakes on LCHF/keto:1. not eating enough - make sure not going below 1200 cal - may lose muscle mass in that case - would slow down ur metabolism2. trying to go low carb and low fat - diet will be bland and boring and will struggle to eat enough cal3. overeating allowed foods - [Why LCHF Diet Works For Diabesity Management](https://www.elearning.dlife.in/lds-course-notes/why-lchf-diet-works-for-diabesity-management-13/) - WHY LCHF works for diabesity management?high carb - 60% of dietlow carb - 20% of dietvegan - carbs - 70-80% diet, 10% - fat, 10% -proteinif we have to walk 1 km to cover the delta in LCHF, would be 2.875 km in vegan and 4.75 km in high carb diet.insulin:LCHF:vegan:high carb = 1:6.68:8.45https://www.dlife.in/dlife-indian-lchf-keto-diet-success-stories/indian-iddm-type-2-lchf-diet-success-story-r-vijayasarathi/https://www.dlife.in/dlife-indian-lchf-keto-diet-success-stories/indian-iddm-type-2-success-story-on-lchf-diet-suresh-gulwadi/https://www.dlife.in/dlife-indian-lchf-keto-diet-success-stories/indian-type-2-diabetes-lchf-diet-success-story-s-k-sharan/https://www.dlife.in/dlife-indian-lchf-keto-diet-success-stories/indian-lchf-diet-iddm-type-2-success-story-bhaskar-motadoo/https://www.dlife.in/dlife-indian-lchf-keto-diet-success-stories/susans-diabetes-reversal-off-from-insulin-success-story-on-indian-lchf-diet/https://www.dlife.in/tag/diabetes-medications/need for - [Carnivore Diet](https://www.elearning.dlife.in/lds-course-notes/carnivore-diet-13/) - Carnivore diet - https://pubmed.ncbi.nlm.nih.gov/27801685/https://pmc.ncbi.nlm.nih.gov/articles/PMC5946211/Dr. Shawn Baker - carnivore king. book in 2018 - orthopedic surgeon. more than 25k members on fb of world carnivore tribe groupJordan Peterson, Mikhaila Peterson - severe arthritis, depression, fatigue, itchy skin into remissiononly foods that either walked, swam or flewaddress autoimmune condition or attempt to loose weight. usually after keto/paleo diet.eat - [The Atkins Diet](https://www.elearning.dlife.in/lds-course-notes/the-atkins-diet-18/) - The Atkins diet - https://pubmed.ncbi.nlm.nih.gov/24723079/https://pubmed.ncbi.nlm.nih.gov/20071648/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1467-789X.2012.01021.xfocus on low carb and was majorly for a weigh loss. promoted by Dr. Robert C Atkins - 1972. wrote a book - The Atkins Diet.shifted focus from calorie diet to eating as much as protein/fats and lowering carbs4 phases - phase 1 - induction (2 weeks) - high fat, high protein, low - [Ketogenic Diet](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-20/) - Ketogenic diet - primary focus - achieve state of nutritional ketosiscontra-indicatins - contraindicated in patients with following health conditions - pyruvate caroxylase deficiency, porphyria, fat metabolim disorders3 states of ketosis - ketosis and diabetic ketosis - wrongly interchangedhttps://www.dlife.in/news-and-research-articles-on-diabetes-obesity-lipids/ketosis-diabetic-ketoacidosis/So what is Ketosis? It is a metabolic state in which the body relies primarily on fats, rather than glucose, - [LCHF Diet](https://www.elearning.dlife.in/lds-course-notes/lchf-diet-20/) - LCHF diet - liver's glycogen storage capacity - 120 gmindividual per meal CHO tolerance becomes basis of thissetting limit on carb intake - 100 gm/day20% CHO energy or 100 gm/day - whichever is the lower of the 2.fat > less fat storage & insulin spike, high fat burningprotein - moderate fat storage and insulin spike, moderate fat - [Anabolic Resistance](https://www.elearning.dlife.in/lds-course-notes/anabolic-resistance-9/) - Notes:ANABOLIC RESISTANCE REFERS TO THE DIMINISHED CAPACITY OF MUSCLES TO SYNTHESIS PROTIEN WHICH LEADS TO LOSS OF MUSCLE MASSTHIS CONDITION IS A SIGNIFICANT FACTOR IN THE AGING PROCESS LEADING TO A DECLINE IN MUSCLE MASS AND FUNCTION OVER TIMEOTHER POPSSIBLE FACTOR - [FOR LOOS OF MUSCLE MASS]AGE RELATED HORMONAL CHANGESINSUFFICIENT PROTIEN INTAKEINSULIN RESISTANCEVASCULAR DYSFUNCTIONOBSITYINFLAMMATIONCHRONIC ILLNESSRAPAMYCIN - [Insulin Resistance & Diabetes](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-diabetes-29/) - Types of DiabetesType 1 (Juvenile) - condition in which immune system destroys β cells in the pancreas, requires you to depend on exogenous insulin for BG control. It is usually diagnosed in children and young people.Type 1.5 (LADA) - Latent Autoimmune Diabetes in Adults - autoimmune condition similar to type 1. It develops at a - [Low Carb Diet](https://www.elearning.dlife.in/lds-course-notes/low-carb-diet-13/) - Low carb diet:Carbs is the limit, protein is the target, fat is the lever. - [Devices & Gadgets](https://www.elearning.dlife.in/lds-course-notes/devices-gadgets-5/) - Notes:Urine strips measure acetoacetate, breath analyzers measure acetone & blood ketone strips measure BHB - [Insulin Resistance & Dyslipidemia](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-dyslipidemia-22/) - Notes:triglycerides and hdl ratio >2.75in males and >1.65in females - [FODMAP Diet](https://www.elearning.dlife.in/lds-course-notes/fodmap-diet-9/) - FODMAP diet - IBS attack - greasy foods, alcohol, raw foods - salad, nuts, big proteins like red meat, alcohol,FODMAP diet - for helping IBS Fermentable oligosaccharides, disachharides, monosachharides, polyols - group of short chain carbs - poorly absorbed in SI - leading to GI discomfort. foods difficult to digestoligosaccharides - wheat, onions,garlicdisachharides - lactose - in dairymonosachharides - [Understanding Autoimmune Conditions, and the Role of Carnivore Diet in Management](https://www.elearning.dlife.in/lds-course-notes/understanding-autoimmune-conditions-and-the-role-of-carnivore-diet-in-management-9/) - Notes:Body's immune system attacks its own tissues - Hashimoto's thyroiditis, Crohns disease, ulcerative colitis - [Follicle-stimulating Hormone](https://www.elearning.dlife.in/lds-course-notes/follicle-stimulating-hormone-28/) - [Aldosterone](https://www.elearning.dlife.in/lds-course-notes/aldosterone-18/) - Notes: - [Aldosterone](https://www.elearning.dlife.in/lds-course-notes/aldosterone-17/) - Notes: - [Vegan Diet](https://www.elearning.dlife.in/lds-course-notes/vegan-diet-11/) - vegan diet - more religious than a dietexcludes anything and everything from animals - including ghee, butter, cheesetofu, legumes, nuts, nut butter - good source of iron, fiber, mg, zinc, selenium, Vit E, seeds - hemp, chia, flaxseeds - protein & omega-3, ca fortified plant milk and yogurt, algae, nutritional yeast, whole grains, sprouted, fermented plant - [South Beach Diet](https://www.elearning.dlife.in/lds-course-notes/south-beach-diet-17/) - South beach diet - commercial diet plan - cardiologist Dr. arthur Agatston, dietician Marie Almon - in mid 1990initially for CVD nut later became wt loss dietfocussed on glycemic index - selecting carbs based on glycemic indexunrefined carbs - low GI scoe - body digests these slowly3 stages - also found in Atkins diet1. kickstarting wt - [Paleolithic Diet](https://www.elearning.dlife.in/lds-course-notes/paleolithic-diet-14/) - Paleolithic diet - caveman diet - stone age diet - 1970 loren cordain - book in 2002about food group exclusion - not macros - so not low carbbased on archeological studies - plants - seeds, wild grown barley, tubers, legumes, flowers, animals - but no dairy as animals were not yet domesticated thenseafood, insects - honey, honeycombsmust eat 0 - [Mediterranean Diet](https://www.elearning.dlife.in/lds-course-notes/mediterranean-diet-15/) - Mediterranean diet - 16 countries - no one diet - like italy, greece in 1960close to american heart association diet, but not closemust have - veggies, fruits, nuts, seeds, legumes, potatoes, whole grains. bread, herbs, spices, fish, seafood, extra virgin olive oilmust moderate - poultry, eggs, cheese, yogurtmust minimize - red meatmust avoid - sugar, refined - [DASH Diet](https://www.elearning.dlife.in/lds-course-notes/dash-diet-19/) - DASH diet - dietary approaches to stop hypertensionUS based heart, lung, blood institute to prevent and control hypertensionflexible, heart healthy dietDASH - ispiration from observation that hypertension was less common in plant based diet and veganno special food req - daily/weekly nutritional goals are providedeating veggies, fruits, whole grains, fat-free, low fat dairy, fish, poultry, beans, - [Whey Protein](https://www.elearning.dlife.in/lds-course-notes/whey-protein-18/) - Whey protein - milk - made of casein, wheywhey - liquid remaining after milk is curdled and strained. byproduct of manufacture of cheese or casein complete protein - all 9 essential amino acids - low lactose content. good source of protein for vegetarians. for improving muscle protein synthesis and promoting growth of lean muscle mass. types - WP concentrate - - [Undenatured Collagen UC -II](https://www.elearning.dlife.in/lds-course-notes/undenatured-collagen-uc-ii-18/) - Undenatured collagen UC - II - type 2 collagen, chicken collagen, hydrolyzed collagen type 2collagen supplements in 2 forms - hydrolyzed collagen or Undenatured collagen UC - II derived from chicken sternum cartilage, benefit for joint, cartilage health - natural collagen production, joint lubrication, redirect immune response which targets cartilage breakdown, no side effects, gluten free, dairy - [Silymarin / Milk Thistle](https://www.elearning.dlife.in/lds-course-notes/silymarin-milk-thistle-19/) - Silymarin/milk thistle: C25H22O10 molas mass - 482.44 g/molflavonoid (colorful veggies) derived from silybum marianum - plant known as milk thistlemost common for liver diseasessilibilin - silybin A and Bbenefits - antioxidant, antiviral, anti-inflammatoryincrease breast milk productiondecrease in acne lesionsreduce blood sugar levelside effects - by mouth - safe, on skin - possibly safe, may cause allergic - [Resistant Starch](https://www.elearning.dlife.in/lds-course-notes/resistant-starch-18/) - Resistant starch - carb that resists digestion in SI and ferments in LI. fermented fiber - act as prebiotic feed good bacteria in gut.diff types - classified by structure and source. multiple Resistant starch can be present in single food. increases production of short chain fatty acids like butyratetype 1 - in grains, seeds, legumestype 2 - raw - [Timed Access & Course Completion Time](https://www.elearning.dlife.in/lds-course-notes/timed-access-course-completion-time-14/) - 2 case of kids with type 1 D (T1D)type 2 D (T2D) - HBA1C 12.8 to 6.0(no med) - [Omega 3 Fatty Acids](https://www.elearning.dlife.in/lds-course-notes/omega-3-fatty-acids-20/) - Omega - 3 fatty acids - key fasmily of polyunsaturated fats. 3 main - marine omega-3 - EPA, DHAALA - most common omega-3 - vegetable oils, nuts - walnuts, flax seeds, flax seed oil, leafy vegetables, animal fat - grass fed animals. ALA - for energy, conversion to EPA, DHA - limitedomega-6 - lenolein acid, arachidonic acid benefits of - [N-Acetylcysteine](https://www.elearning.dlife.in/lds-course-notes/n-acetylcysteine-24/) - N-acetylecestein - NAC - N-acetyl-L-cysteine - NALCmolas mass - 163.195 g.mol-1C5H9NO3Ssupplement form of amino acid cystein. helps in respiratory diseases, liver disease, psychiatric disorders, diabetes, certain cancers, chemical dependencythru IV, by mouth or inhaled as a mistused as a medication to treat paracetamol overdose and to loosen the mucus in bronchitis/pneumoniaNAC > transformed into amino acid - [MCT Oils](https://www.elearning.dlife.in/lds-course-notes/mct-oils-20/) - MCT oils - made up of MCT fats - found in coconut oil, palm kernel oil, dairy products.mainly for wt loss, endurance during workout.MCT - medium chain fatty acid - 10% fewer calories than LCT - long chain triglycerides/fatty acidLCT - 12 to 18 carbons longMCT. -6-10 carbon links. C6 - caproic or hexanoic acidC8 - caprylic - [L Theanine](https://www.elearning.dlife.in/lds-course-notes/l-theanine-19/) - L-Theanine - L-gamma-glutamylethylamide and N5-ethyl-L-glutamine - amino acid analog of proteinogenic amino acids L-glutamate, L-glutamine.C7H14N2O3 - mol wt - 174.200 g.mol-1amino acid in tea leaves. by japanese scientist in 1949. also found in some mushroomsin green tea - source of umami, savory, brothy tastebenefits - reduces stress, anxiety, increased focus, better immunityside effects - preg/lactating - should - [L Proline](https://www.elearning.dlife.in/lds-course-notes/l-proline-18/) - L proline - imino acid - 1900 by Richard Willstatter C5H9NO2 - molar mass - 115.132 g.mol-1one if the 20 amino acids - used as building blocks of protein. proline - major amino acid found in cartilage - youthful skin, repair and maintain muscle, connective tissue and skin damage. essential component of collagen - imp for joints - [L Lysine](https://www.elearning.dlife.in/lds-course-notes/l-lysine-19/) - L Lysine - Lysine, D-lysine, LYS, h-lys-OHC6H14N2O2mol wt - 146.190 g.mol-1essential amino acid. 8 gm/day or 12 mg/kg in adults children - 44 mg/kg per day, 97 mg/kg/day - for 3-6 month oldLysine - from german biological chemist Ferdinand - 1889 from protein casein milk. humans cannot synthesis so essential amino acid from dietorganisms that synthesize Lysine - - [Understanding Migraines: Causes, Connections, and Management](https://www.elearning.dlife.in/lds-course-notes/understanding-migraines-causes-connections-and-management-6/) - Notes:Migraine PhasesProdrome - Mood changes, fatigueAura - Visual or sensory disturbancesHeadache - Main attack pahsePostdrome - Fatigue or confusionMigraine attacks are often triggered by electrolyte imbalances (especially sodium and potassium), carbohydrate intake (which displaces sodium from cells), dehydration, stress hormone surges (regardless of positive/negative emotions), and high-potassium foods like bananas and chocolate - [L Leucine](https://www.elearning.dlife.in/lds-course-notes/l-leucine-20/) - L Leucine - L-enantiomer of leucine - C6H13NO2Leucine - one of the 9 essential amino acids -proviced by food. protein synthesis.regulate blood sugar, growth, repair of muscle, bone tissue, growth hormone production, wound healing. def. is rarealpha-amino acid - contains alpha amino group, alpha carboxylic acid group, side chain isobutyl group - making it non-polar aliphatic amino - [L Citrulline](https://www.elearning.dlife.in/lds-course-notes/l-citrulline-18/) - L Citrulline - produced in body - as a byproduct of nitric acid from amino acid arginine - catalyzed by nitric oxide synthase. alpha-amino acidH2NC(O)NH(CH2)3CH(NH2)CO2H - molas mass - 175.188 g/molL Citrulline - made from ornithine, carnamoyl phosphate - in central reaction in urea cycle. arginine > N-hydroxy-arginine > citrulline concomitant + nitric oxide. types - L Citrulline - Citrulline - [Insulin](https://www.elearning.dlife.in/lds-course-notes/insulin-24/) - Insulin is a polypeptide hormone produced by the pancreatic β cells. It has many vital functions.Insulin acts like a key, unlocking cells to take up glucose (carb and part of proteins are metabolized into glucose) from the bloodstream after a meal which is used for energy production. This regulates BG level and keep it normal.It - [L-Carnitine](https://www.elearning.dlife.in/lds-course-notes/l-carnitine-18/) - L-Carnitine - L-carnitine, acetyle-L-carnitine, propionyl-L-carnitinefrom amino acids - in all body cellscritical role - energy productiontransports long chain fatty acids into mitochondria - so they can be oxidized to produce energy. in skeletal, cardiac muscles -which utilize fatty acid as a dietary fuel. body makes sifficient L-carnitinetypes - L-carnitine - biologically active form:D-carnitine - inactive form - - [Inositol](https://www.elearning.dlife.in/lds-course-notes/inositol-18/) - Inositol - myo-inositol, cis-1,2,3,5-trans-4,6-cyclohexanehexol, cyclohexanehexol, mouse antialopecia factor, nucite, phaseomannite, phaseomannitol, rat antispectacled eye factorm scyllite vit B8carbocyclic sugar - abundant in brain, mammalian tissues mediates cell signal transduction in response to hormones, neurotransmitters, growth factors, participates in osmoregulation.C6H12O6 - 180.16 g/molsugar alcohol -half the sweetness of sucrose. made from glucose naturally in humans.human kidney - - [Glutamine](https://www.elearning.dlife.in/lds-course-notes/glutamine-17/) - Glutamine - L-glutamine, levoglutamide, 2,5 diamino-5-oxopentanoic acid, 2-amino-4-carbamoylbutanoic acid, endaralpha-amino acid - affects processes of growth and function of cells in stomach and intestine. used in biosynthesis of proteins. similar to glutamic acid - except carboxylic acid group replaced by amide. charge-neutral, polar amino acidC5H10N2O3 - molar mass - 146.146 gm.mol-1Glutamine - most abundant amino acid in blood, - [Glucosamine, Chondroitin, MSM Plus Hyaluronic Acid](https://www.elearning.dlife.in/lds-course-notes/glucosamine-chondroitin-msm-plus-hyaluronic-acid-15/) - Glucosamine, Chondroitin, MSM plus hyaluroic acid:Glucosamine - natural chemical compound in bodyamino sugar - precursor in biochemical synthesis of glycosylated proteins and lipid. part of polysaccarides, chitosan, chitin - C6H13NO5 - molas mass - 179.172 g/mol 2 main forms - hydrochloride, sulfate. helps in cartilage healthfound in shellfish shells, animal bones, fungi.side effects : likely safe, - [Gelatin](https://www.elearning.dlife.in/lds-course-notes/gelatin-16/) - Gelatin - 98-99% derived from collagen - most pletiful protein, partial hydrolysis of collagen - unique amino acid profilegelatin, collage hydrolysate - powder form glycine - 27%, proline - 16%, valine - 14%, hydroxyproline - 14%, glutamic acid - 11%benefits - lifts your mood, cognitive abilities - glycine - inhibitory neurotransmitter -anti-anxiety, helps lower stress hormones - [Flaxseed Oil](https://www.elearning.dlife.in/lds-course-notes/flaxseed-oil-15/) - Flaxseed oil - linseed oilcod pressed from flaxseeds -contains plant based omega-3, ALA7 gm/tablepoon - rich source. only 10-15% of omega-3s gets used - rest is burnt as energy.1 tablespoon of flaxseed oil - 700 mg of EPA, DHAbenefits - gives omega03 for pure veg, improve heart health by reducing BP, increase elasticity of arteries, - [Exogenous Ketones](https://www.elearning.dlife.in/lds-course-notes/exogenous-ketones-16/) - Exogenous ketones - help achieve ketosis - contain only beta-hydroxybutyrate2 main keto bodies - acetoacetate, beta-hydroxybutyrate. acetone - 3rd less abundant ketone body.ketone salts (KS) - ketones bound to salt - sodium, potassium, Ca or Mg. - powder form - mixed with liquid.Ketone esters (KE) - ketones linked to ester - in liquid form. increase blood - [Egg Shell Membrane](https://www.elearning.dlife.in/lds-course-notes/egg-shell-membrane-20/) - Egg shell membrane - calcium carbonate (common form of calcium), rest is protein, minerals. 40% Ca - each gram providing 381-401 mganti-inflammatory, wound healing prop, powder effective on bone, cartilage -suitable for osteoporosis treatment, improve joint health, half egg shell - meet avg daily Ca req for adultside effects - no large fragments 0 may hurt - [Curcumin / Turmeric](https://www.elearning.dlife.in/lds-course-notes/curcumin-turmeric-18/) - Curcumin/Turmeric:major source of polyphenol curcuminbenefits - reduce inflammation, improve antioxidant status - improve blood vessel function - dilation, increase blood flow, reduce BP, reduced heart attack risk.side effects - generally safe -m 2% oxalate - can cause kidney stones if excess in predisposed individualsexcess can cause - digestive issues (more than 1000mg/day), headache, nausea, skin - [Creatine](https://www.elearning.dlife.in/lds-course-notes/creatine-22/) - Creatine - N-Carbamimidoyl-N-methylglycine - methylguanidoacetic acid - C4H9N3O2 - mol. wt - 131.135 g/molbioactive substanceproduced from amino acids - made in liver, some in kidney, pancreas.stores high energy phosphate groups in form of phospocreatine - donated to ADP - converted to ATPnitrogen containing metabolite - from 3 amino acids - L-arginine, glycine, L-methionine. - 1% - [CoQ10](https://www.elearning.dlife.in/lds-course-notes/coq10-21/) - CoQ10 - C59H90O4 - Ubiquinone -10molas mass - 863.365 g.mol-1antioxidant - naturally produced - for growth n maintenance - decrease with age, low in heart disease peopleUbiquinone - ubiquitous in animals and most bacteriamost common - Ubiquinone 10reduced biosynthesis and excess use by bodystatins - should take CoQ10food - meat, fish - levels over 650 - [Collagen](https://www.elearning.dlife.in/lds-course-notes/collagen-18/) - Collagen - main structural protein in extracellular matrix - most abundant in mammals - 25-35% of whole body protein.bones, skin, muscles, tendons, ligaments,also blood vessels, corneas, teeth, - glue holding all these things tgether.greek word kolla - means glueatleast 16 types - 4 main type are -I - 90% of body - densly packed fibers, provides - [Cinnamon](https://www.elearning.dlife.in/lds-course-notes/cinnamon-18/) - Cinnamon: imported to egyptadults - max 1 teaspoon of cassia cinnamon per dayantioxidant - prevent oxidative dsmsage from free particlesimprove key factors for heart disease, anti-inflammatoryincrease insulin sensitivityreduce fasting blood sugar levels, cinnamaldehyde - antifungal and antibacterial - fight tooth decay, bad breath but also can cause mouth sore. chewing gums have itside effects - - [Ketogenic Diet & Mental Health](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-mental-health-7/) - Notes:Keto diet benefitsEnhanced energy supplyReduced inflammationbalanced neurotransmittersOxidative stress reductionGut brain axis support - [Incretin — GLP-1 And GIP](https://www.elearning.dlife.in/lds-course-notes/incretin-glp-1-and-gip-26/) - Incretins are hormones secreted from the intestine, triggered by the presence of nutrients, such as glucose, carbohydrates, and fatty acids, in the gut after a meal. The two main incretin hormones are glucose-dependent insulinotropic polypeptide (GIP), also called gastric inhibitory polypeptide, and glucagon-like peptide-1 (GLP-1). When you take glucose orally, your body releases incretins, leading - [Ketogenic Diet For Alzheimer’s Disease](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-for-alzheimers-disease-6/) - Notes:Alzheimers - Brains ability to utilise glucose as energy source diminishes however it can effectively use ketones which are produced during fat metabolism when carb intake is low.Primary Ketone - BHB - [Notes Taking Explained](https://www.elearning.dlife.in/lds-course-notes/notes-taking-explained-26/) - explaining the interface - [Ketogenic Diet & Polycystic Kidney Disease](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-polycystic-kidney-disease-5/) - Notes:PKD - Genetic disorder - Formation of numerous cysts in kidneys leading to kidney enlargementADPKD (Autosomal dominant) - 90% of cases - High bp, CKDAARPKD (Autosomal Recessive) - Rarer - [Casein](https://www.elearning.dlife.in/lds-course-notes/casein-19/) - Casein: family of related phosphoproteins (alphaS1, alphaS2, beta, k) present in mammalian milk. forms 80% of bovine milk proteins, forms large colloidal particles with calcium phosphate to form casein micelles. casein provides - carbs, protein, 2 essentials elements - calcium, phosphorous.major anti-catabolic protein - prevents protein breakdown.2 main forms: micellar casein - most popular, digested slowly natural undenatured form of - [β-Alanine](https://www.elearning.dlife.in/lds-course-notes/β-alanine-19/) - Beta-Alanine: C3H7NO2naturally occurring beta amino acid - molas mass 0 89.093 g/mol.modified version of alanine - and is a non-essential amino acid. building block of carnosine - molecule that helps buffer acid in muscles. enhance muscle endurance.moderate to HIIT cardiovascular exercise performance improves - like rowing/sprinting. can aid lean mass gain. carnisine - antioxidant, anti-aging compound. unlike most amino - [Berberine](https://www.elearning.dlife.in/lds-course-notes/berberine-19/) - Berberine: C20H18NO4+molecular wt = 336.366 g/molquaternary ammonium salt from protoberberine group of benzylisoquinone alkaloids. found in plants like berberis , tree turmeric, yellowroot, oregon grape. amur cork tree, chinese goldthread, prickly poppy, californian popyy.berberine - usually found in roots, rhizomes, stems, bark. lower blood sugar, cause wt loss, improve heart health - as good, effective as pharma - [BCAA](https://www.elearning.dlife.in/lds-course-notes/bcaa-22/) - BCAA: branched chain amino acids3 amino acids -leucine - 2 amino 4 methylpentanoic acid,releases growth hormones (HGH) - stimulates muscle growth, release of insulin, boosts protein synthesis, inhibit muscle breakdown. ketogenic amino acid. 5 gm dailyisoleucine - 2 amino 3 methylpentanoic acid - needed for formation of HB, regulation of blood sugar. 2 gm failyvaline - [Astaxanthin](https://www.elearning.dlife.in/lds-course-notes/astaxanthin-21/) - Astaxanthin - C40H52O4molar mass - 596.841 g/molnaturally occurring carotenoid - in algae, shrimp, lobster, crab, salmon. carotenoids - pigment colors - in nature and support good health. ex. beta-carotene - orange.xanthophylls - oxygen-containing carotenoids - have yellow pigment. ex. astaxanthin, beta-cryptoxanthin, lutein, zeaxanthin.foods rich in xanthophylls - pumpkin, egg yolks, avocado, summer squash, spinach, kale. linked to - [Ashwagandha](https://www.elearning.dlife.in/lds-course-notes/ashwagandha-20/) - Ashwagandha: Withania Somniferaroot has horsey smell - confer strength and virility of horse. most common in supplements is root extract.benefits:reduce stress & anxiety, reduce depression, boost testosterone & increase fertility in men, increase muscle mass & strength, reduce inflammation (CRP markers), lower cholesterol & triglycerides, improve brain function & memory, reduce cortisol levels, anti cancer - [Alpha Lipoic Acid](https://www.elearning.dlife.in/lds-course-notes/alpha-lipoic-acid-24/) - alpha lipoic acid: ALA - lipoic acid/thioctic acid - C8H14O2S2molecular wt - 206.32 g-mol^-1organosulfur compund - derived from caprylic acid.made in animals, essentials for aerobic metabolism. ALA - naturally occurring fatty acid - yeast, spinach, broccoli, potatoes, organ meats like liver/kidneysLA - contains 2 sulfur atoms - C6, C8 - connected by disulfide bondmarketed as antioxidant.both - [Supplements](https://www.elearning.dlife.in/lds-course-notes/supplements-10/) - Supplements:vit, minerals, amino acids, fatty acids, other substances in form of pills, tablets, capsules, liquid etc - [Low Carb & Ketogenic Diet For Kidney Disease](https://www.elearning.dlife.in/lds-course-notes/low-carb-ketogenic-diet-for-kidney-disease-5/) - Notes:CKD is caused byHigh BPDiabetes - Diabetic kidney diseaseHigh cholestrolKidney inflammationPolycystic kidney diseaseKidney stonesNSAIDsSGLT2 inhibitors increase glucosuria, resulting in reduced insuulin action & increased blood ketones - [Chromium](https://www.elearning.dlife.in/lds-course-notes/chromium-19/) - Chromium:needed in small amounts. cannot be made in body - from diet/supplements. mechanism and amount needed in body - not well defined.adults: upto 50 years - male - 35 mcg, females - 25 mcgpreg - 30 mcg, lactation - 45 mcg> 50 years - male - 30 mcg, females - 20 mcg2 forms:1. trivalent - chromium - [Human Growth Hormone](https://www.elearning.dlife.in/lds-course-notes/human-growth-hormone-13/) - Human growth hormone (HGH), also called somatotropin, is a peptide hormone produced by the pituitary gland that stimulates growth, cell reproduction, and cell regeneration. HGH also stimulates production of insulin-like growth factor 1 (IGF-1) and increases the concentration of glucose and free fatty acids. A compensatory increase in insulin secretion can balance the glucose raising - [Ghrelin](https://www.elearning.dlife.in/lds-course-notes/ghrelin-25/) - Ghrelin is a hormone produced mainly by the stomach that is known as the “hunger hormone” because it stimulates appetite. The name is based on its role as a growth hormone releasing peptide. Its levels are affected by our normal meal routine. It signals the brain to feel hungry, and its levels rise before meals - [Molybdenum](https://www.elearning.dlife.in/lds-course-notes/molybdenum-17/) - Molybdenum: Molil amount is needed - without this sulfites and toxins would build up in bodystructural constituent of molibdoprotein - cofactor synthesized by body and needed in activity of 4 enzymes:1. sulfite oxidase - sulfite > sulfate conversion2. xanthine oxidase - xanthine > uric acid conversion - helps break down nucleotides (building blocks of DNA) - [Selenium](https://www.elearning.dlife.in/lds-course-notes/selenium-17/) - Selenium: (Se)essential trace mineral - imp function - cognitive function, healthy immune sys, fertility in men, women bothpresent in human tissue, mostly in skeletal muscle.constituent of more than 2 dozen selenoproteins - critical role in: reproduction, DNA synthesis, thyroid metabolism, protection from oxidative damage and infection.selenium - 2 formsinroganic - selenate, seleniteorganic - selenomethionine, selenocysteineselenocysteine, selenite - [Glucagon](https://www.elearning.dlife.in/lds-course-notes/glucagon-31/) - Glucagon is a peptide hormone produced by the pancreas that signals the liver to break down stored glycogen into glucose. Glucagon works along with insulin to keep BG within set levels. It is released to not let BG fall too low (hypoglycemia), while insulin is released to not let BG rise too high (hyperglycemia). Glucagon - [Iodine](https://www.elearning.dlife.in/lds-course-notes/iodine-19/) - Iodine:Iodine is a micronutrient that is essential for the production of thyroid hormones.imp component of thyroid hormones - thyroxine (T4), triiodothyronine (T3)imp in protein synthesis, enzymatic activity, critical determinants of metabolic activity. skeletal, CNS development in infants and fetuses.thyroid function - regulated by TSH - thyrotropin.TSH secretion > increase in thyroidal uptake of iodine > - [Thyroid Function Test (TFT)](https://www.elearning.dlife.in/lds-course-notes/thyroid-function-test-tft-7/) - Notes:TSH, Free T3 & Free T4ThyroglobulinTSH - 0.4 - 4FT4 - 0.7 - 1.8 (Impacts metabolism)FT3 - 2.3 - 4.2Tg - High levels can indicate cancerHypo - TSH High, FT4 LowHyper - Low TSH, High FT4 & FT3 - [Manganese](https://www.elearning.dlife.in/lds-course-notes/manganese-18/) - Manganese:essential trace element - 10-20 mg Manganese - 25-40% in bone. rest in liver, pancreas, kidney, brainregulation of absorption & excretion. more than 90% - excreted in bile thru feces, small amount reabsorbed, very lil excreted thru urine.functions:amino acid, cholesterol, glucose, carb metabolismbone formationreproductionimmune responseanti-inflammatory - due to role as part of powerful antioxidant superoxide dismutase - [Iron](https://www.elearning.dlife.in/lds-course-notes/iron-19/) - Iron: mineralneeded for growth n developmentto make hemoglobin, a protein in red blood cells that carries oxygen from the lungs to all parts of the body and myoglobin, a protein that provides oxygen to muscles. to make some hormones and connective tissue.adult men - 8 mgadult female - 18 mgpreg - 27 mglactation - 9-10 - [Zinc](https://www.elearning.dlife.in/lds-course-notes/zinc-22/) - Zinc:Since its first discovery in an Iranian male in 1961, zinc deficiency in humans is now known to be an important malnutrition problem world-wide. Phytic acid is the main known inhibitor of zinc.Zinc:helps the immune system fight off invading bacteria and viruses.to make proteins and DNADuring pregnancy, infancy, and childhood, the body needs zinc to grow - [Copper](https://www.elearning.dlife.in/lds-course-notes/copper-21/) - Copper: trace mineral - part of enzymes, proteins - essential for adequate use of iron. cofactor for at least 12 cuproenzymes involved in - energy production, iron metabolism, neuropeptide activatation, connective tissue synthesis, neurotransmitter synthesis.abundant cuproenzyme (enzymes that require one or more copper atoms to function) - ceruloplasmin (CP) - iron metabolism, carries 95% of total - [Gastrin](https://www.elearning.dlife.in/lds-course-notes/gastrin-17/) - Gastrin is a peptide hormone released by G-cells of the gastric antrum and duodenum, triggered by vagal nerve stimulation, entry of food in stomach (particularly peptides and amino acids), stomach distention, increased stomach pH, and hypercalcemia. It stimulates stomach acid production, promotes gastric motility, and aids in digestion. Elevated levels of stomach acid (low pH) - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-87/) - Notes:10 meter long digestive tube from mouth to anus. mouth, esophagus, stomach, small intest, large intest and anus.liver , pancreas and gallbladder are solid organs of the digestive track.3 parts of small intestines - duodenum, jejunum and ileum.large intestine includes appendix, cecum, colon and rectum. appendix is a finger shaped pouch attached to the cecum. colon - [Insulin Resistance & Diabetes](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-diabetes-28/) - Notes:fbs901hrppbs1402hrppbs120A1c5.66 - [Magnesium](https://www.elearning.dlife.in/lds-course-notes/magnesium-25/) - Magnesium:protein synthesis, BP, hormone binding, muscle contraction, nerve functionsymptoms: stress/anxiety, high BP, muscle contractin, sleep disturbance, constipation, palpitations, cignition, headachesMG asparte - 42-45% absorptionMG lactate - 42%MG citrate - 30% - good for constipation*MG glycinate - calms things down - 24% general use for calmingMG chloride - low stomach acid issues can be resolve or - [Sulfur](https://www.elearning.dlife.in/lds-course-notes/sulfur-21/) - Sulfur:after ca, phosphorus, most abundant - derived exclusively from proteins, only 2 of 20 amino acids in proteins contain sulfur.1 - methionine - cannot be generated in body, only in diets 2. cysteine - sulfur containing amino acidproteins - 3-6% of sulfur amino acids. small % comes from in inorganic sulfates, organic sulfur present in garlic, onion, - [Phosphorus](https://www.elearning.dlife.in/lds-course-notes/phosphorus-20/) - Phosphorus: second most plentiful mineral after ca. Phosphorus & phosphate irons - critical role in bone structure &essential cellular functions. dietary Phosphorus absorbed in SI. bones - strong, healthy, muscle movement, make energy.bone - principal reservoid of Phosphorusfunctions:build strong, healthy bones, filter our waste in kidneys, manage energy usage and storage, grow, maintain, repair tissue,cells, produce DNA, - [Calcium](https://www.elearning.dlife.in/lds-course-notes/calcium-22/) - Calcium:more CA supplements - more bone desntiy - more risk of breast cancermpre calcium inside cell - more oxidation inside - more cancermagnesium - decreases prolonged risk of death.vit K - inhibit calcification, decreases risk of fracture.Vit C, K, D, magnesium - positive effect on calcium toxicityD - regulating upto 2000 genes. essential fatty acids - - [Insulin Test – Setting The Bar Right](https://www.elearning.dlife.in/lds-course-notes/insulin-test-setting-the-bar-right-21/) - Notes:insuline 6-7 - [Excess Post-exercise Oxygen Consumption (EPOC)](https://www.elearning.dlife.in/lds-course-notes/excess-post-exercise-oxygen-consumption-epoc-7/) - Notes:EVEN AFTER YOUR WORKOUTS OVER AND YOU ARE BACK TO YOUR DAILY ROUTINE YOUR BODYS METABOLISM CAN CONTINUE TO BURN MORE CALORIES THEN WHEN AT COMPLETE RESTTHIS EFFECT IS CALLED EXCESS POST-EXCERSICE OXYGEN CONSUMPTIONWHAT IS EPOC?REPLENISH ENERGY STORESREPAIR TISSUESREMOVE LACTATERESTORE OXYGEN LEVELS ON BLOOD AND MUSCLESELEVATE BODY TEMP BACK TO NORMALMANAGE HORMONAL ADJUSTMENTS POST-EXCERSICE - [Muscle Gain](https://www.elearning.dlife.in/lds-course-notes/muscle-gain-10/) - Notes:ALWAYS CONSIDER LBM FOR FAT LOSS AND ALSO FOR MUSCLE GAIN IF AN INDIVIDUAL IS WITHIN IDEAL WEIGHT RANGE BUT CARRIES FAT AND HAS LESS VISIBLE MUSCLESAN ATHLETE WHO WANTS TO BUILD MORE MUSCLES AND IMPROVE HUS ATHLETUC PERFORMANCE ALWAYS CONSIDER IBW FOR SUCH INDIVIDUALS RATHER THAN LBW - [Weight Loss](https://www.elearning.dlife.in/lds-course-notes/weight-loss-10/) - Notes:IF AN INDIVIDUAL IS NOT EXPERIENCING WEIGHT LOSS WE SUGGEST LOWERING THE FAT INTAKE AND REPLACE THOSE CALORIES WITH FIRST-CLASS PROTIENS PROTIEN WILL KEEP INDIVIDUAL FULL FOR A LONGER PERIOD OF TIME HENCE MEAL FREQUENCY WILL BE DELAYED FOR EVERY 5GMS OF FATS REPLACE IT WITH 10GMS OF PROTIEN - [Diet And Supplement Planning Goals](https://www.elearning.dlife.in/lds-course-notes/diet-and-supplement-planning-goals-12/) - Notes:MAGNESIUM HELPS CALCIUM ABSORB SO TAKING BOTH TOGETHER CAN CAUSE ABDORPTION ISSUES SUCH AS INTERFERE IN EACH OTHERS ABSORBPTIONHOWEVER CALCIUM:MAG 1:1 CAN WORK WELL WITHOUT CAUSING ANY ISSUESTHE HIGHEST YIELD OF MAGNESIUM IS FOUND IN MAGNESIUM GLYCINATEWHAT IS OFTEN MISSED OUT IS WHILE TAKING A CALCIUM SUPPLEMENT IS OTHER ABSORPTION CO-FACTOR WILL LEAD TO MALABSORPTION - [Cortisol](https://www.elearning.dlife.in/lds-course-notes/cortisol-24/) - Cortisol is a steroid hormone and a stress hormone produced mainly by the adrenal glands, and in lower quantities in other tissues. It regulates a wide range of bodily processes including metabolism and immune response. It plays a vital role in helping the body respond to stress. On perceiving a threat, adrenocorticotropic hormone (ACTH) is - [Notes Taking Explained](https://www.elearning.dlife.in/lds-course-notes/notes-taking-explained-25/) - Notes: - [Niacin](https://www.elearning.dlife.in/lds-course-notes/niacin-21/) - Niacin: Vitamin B3: Nicotinic acid- pyridine-3-carboxylic acid, nicotinamide - niacinamide or pyridine-3-carboxamidederivatives: nicotinamide adenine dinucleaotide (NAD) & nicotinamide adenine dinucleaotide phosphate (NADP) - conenzymes in oxidation-reduction reaction.NAD- active form, NADP - another active form.NAD, NADP - req in most metabolic redox processes - carba, fats, protein to ATP, control of gene expression, cellular communication, maintenance - [Liver Function Test (LFT)](https://www.elearning.dlife.in/lds-course-notes/liver-function-test-lft-6/) - Notes:ALT - Plays a role in protein metabolism. High levels indicate liver damage or inflammation as ALT is released into bloodstream.AST - Found in liver, heart & muscles. High levels can indicate liver/other organ damage.GGTBilirubin - Byproduct of RBC breakdown processed by liver. High levels can lead to jaundiceAlbumin - Protein synthesized by liver. Low - [Folate](https://www.elearning.dlife.in/lds-course-notes/folate-19/) - Folate: Vit B9: FA > DHF > THF - tetra hydro folate (active form of folic acid)biochemical function: one carbon metabolism - transferrable carbon - ex. methyl, methylene, methenyl, formyl, formininoYeF - methylene THF > methenyl THF (histiline is the source)> formyl THF (formate is the source)source for 1 carbon compound - serine, glycine, cholineimp in - [Biotin](https://www.elearning.dlife.in/lds-course-notes/biotin-18/) - Biotin: Vitamin H: water soluble vit, cofactor for:propionyl-CoA carboxylase, pyruvate carboxylase, methylcrotonyl-CoA carbolase, acetyle CoA caboxylase 1, acetyle CoA caboxylase 2 all these coenzymes needed for metabolism of fatty acid, glucose, amino acids.Biotin - histone modification, gene regulation, cell signaling.most biotin in food - bound to protein. free biotin absorbed in SI and most biotin stored in - [Pantothenic Acid](https://www.elearning.dlife.in/lds-course-notes/pantothenic-acid-20/) - Vitamin B5 - Pantothenic Acid/Pantothenate:will give u CoAdef. extremely rare, toxicity very rarefrom everywhere - all foods will have itpanto - all, thenic - strenthmeat, fish, fruits, veggies, seeds we get CoA from B5. fatty acid synthesis and oxidation - need CoA, pyruvate to acetyl CoAacetyl CoA - starts TCA cycle, forms acetylecholine, acetylation reaction, cholesterol synthesis, - [Cholecystokinin](https://www.elearning.dlife.in/lds-course-notes/cholecystokinin-16/) - Cholecystokinin (CCK) is a peptide hormone responsible for stimulating the digestion of fat and protein. It is synthesized and secreted by enteroendocrine cells in the duodenum. Its presence causes the release of pancreatic juice from the pancreas and bile from the gallbladder. CCK leads to release of 70-80% of pancreatic enzymes. CCK is composed of - [Riboflavin](https://www.elearning.dlife.in/lds-course-notes/riboflavin-20/) - Vitamin B2: RiboflavinFMN, FAD - cofactors of enzymes - enzyme helperssolubility is slightly lowerredox - reduction-oxidation reactionfish, eggs - B2 anything needing HCL to be absorbed, gets absorbed in duodenumphosphate from ATP.FAD - stored in liver TCA - citric acid cycle - succinate to fumarate -> need FAD kinase - always adds a phosphate triglycerides > glucose-6Pfatty acids > - [Thiamine](https://www.elearning.dlife.in/lds-course-notes/thiamine-21/) - Thiamine: Vitamin B1: anti beriberi, anti neuritic vitaminpyrimidine + thiazole - connected by methylene > Thiamine TPP thiamine pyruphsophte active form.biochemical functions:1. energy generation2. transmission of nerve impulse.cleavage of carbon-carbon bond, decarboxylation of alpha keto acids - puruvate > acetyle CoA - NAD converted to NADH with TPP helpalpha keto glutarate > succinyl CoAbranched alpha - [Amylin](https://www.elearning.dlife.in/lds-course-notes/amylin-27/) - Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide glucoregulatory hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio of approximately 100:1 (insulin:amylin), triggered by nutrient influx to the GIT. Amylin plays a role in glycemic regulation by slowing gastric emptying, inhibiting digestive secretion (gastric acid, pancreatic enzymes, bile ejection), - [Vitamin B12](https://www.elearning.dlife.in/lds-course-notes/vitamin-b12-24/) - vitamin B12: Cobalamincorrin ring with cobalt. main site for absorption is ileum. active form: adenosyl B12 Methyl B12catalyses 3 reactions - MMS - methyl malonyl coenzyme A mutase, methionine synthasedef. leads to megaloblastic anaemia, subacute combined degeneration of spinal cord.digestion - salivary glands secrete R-binder, gastric parietal cells secrete IF - imp for digestion of B12. B12 - R-binder binds - [Vitamin B6](https://www.elearning.dlife.in/lds-course-notes/vitamin-b6-21/) - Vitamin B6:trans aminases anzyme - transamination.pyridoxine - will cause dermititis forms of B6: pyridoxine, pyridoxaldecarboxylation - remove CO2.def. of B6 - epilepsy (excitation)helps in carbs, protein, fats.pyridoxal - best form of B6 - pyridoxine -> pyridoxal -> pyridoxal phosphate (PLP)natural - fruits, yeast, cereal, veggies grains, egg yolk, meat, fishglycogen metabolism, decarboxylationhelp make - niacin (B3) - - [Vitamin K](https://www.elearning.dlife.in/lds-course-notes/vitamin-k-22/) - Vitamin K:fat soluble - organic compoundK (potassium) - inorganic molecule - completely diff thingsfrom diet or supplementsosteoporosis, cancer - in this can be helpfulk2 - essesntial for coagulation - for prothrombin formation needed - without this no blood clot happens.K - strengthens bones - high density - may help prevent fractures in old womenosteocalcin - - [Vitamin E](https://www.elearning.dlife.in/lds-course-notes/vitamin-e-21/) - Vitamin E: anemia, muscle dystrophy, retinopathy, warfarin + E = big nofat soluble - stored in liver, fat cells, muscle cells.malabsorption syndrome -> leads to def. tocopherols -alpha - most potent, beta, gamma, deltaphenolic hydroxo groupRDA ~ 20 IU/daysynthesis of coQ enzymeproblem gut, intestine and liver -> E def. - [Vitamin D](https://www.elearning.dlife.in/lds-course-notes/vitamin-d-21/) - Vitamin D:Vitamin D can temper inflammation and, thus, has been examined for efficacy in inflammation-associated disorders [51, 52]. This includes cancer chemopreventionStudy designs that focus on gender-selective cancers such as breast or prostate cancers inherently bring variability that may influence conclusions as to the effectiveness of vitamin D supplementation.Vitamin D is increasingly recognised to play an - [Vitamin C](https://www.elearning.dlife.in/lds-course-notes/vitamin-c-23/) - Vitamin C:water-solublewhy imp? not only a vitamin, its a nutrient. needed in vastly larger amounts than u get in food.we sll share a deficiency that one of the 4 enzymes cannot produce Vit C from glucose. many wild animals do it - 8/9/20 gm of Vit C - directly secreted in to the blood.Vit C - [Iron Profile Test](https://www.elearning.dlife.in/lds-course-notes/iron-profile-test-6/) - Notes:High ferritin levels can indicateHemochromatosis - Iron Overload - Accumulation of iron in liver, heart & pancreas - [Kidney Function Test (KFT)](https://www.elearning.dlife.in/lds-course-notes/kidney-function-test-kft-8/) - Notes:CKD - Gradual loss of kidney function over time. Leading causes are diabtes & high BP.Acute Kidney Injury - Sudden decline in kidney function - Severe dyhdrationT1 & T2 D - Can lead to diabetic kidney diseaseNormal GFR - 90 -120 ml/min - [Adiponectin](https://www.elearning.dlife.in/lds-course-notes/adiponectin-30/) - Adiponectin is a protein hormone and adipokine (proteins secreted by adipose tissue) that plays a crucial role in glucose and lipid metabolism, insulin sensitivity, and reducing inflammation, also possess anti-atherogenic properties. Low adiponectin levels are associated with metabolic syndrome, obesity, T2D, and CVD. It is produced primarily in adipose tissue, but also in muscle and - [Diet Heart Hypothesis](https://www.elearning.dlife.in/lds-course-notes/diet-heart-hypothesis-27/) - Notes:The diet heart hypothesis states that fat - [The Randle Cycle: Understanding the Glucose-Fatty Acid Cycle](https://www.elearning.dlife.in/lds-course-notes/the-randle-cycle-understanding-the-glucose-fatty-acid-cycle-8/) - Notes:THE RANDLE CYCLE IS BASICALLY THE COMPETITION BETWEEN GLUCOSE AND FAT WHICHEVER IS HIGH IN THE BLOOD THE BODY\CELL USES IT FOR PROVING ENERGYMORE FATS RESULTS IN LESS GLUCOSE BURNINGMORE GLYCOSE RESULTS IN LESS FAT BURNING - [Three States Of Ketosis](https://www.elearning.dlife.in/lds-course-notes/three-states-of-ketosis-15/) - Notes:KETOGENESIS IS A METABOLIC PATHWAY THAT PRODUCES KETONE BODIES WHICH PROVIDE ALTERNATE ENERGY FOR THE BODY ALSO OUR BODY IS CONSTANTLY PRODUCING SMALL AMOUNTS OF KETONE BODIES THAT CAN MAKE UPTO 22ATP IN THE STATE OF KETOSIS KETONE BODY PRODUCTION INCREASES WHEN THERE IS DECREASED IN THE AMOUNT OF CARBS OR INCREASE OF FATTY ACIDSHOWEVER KETOACIDOSIS CAN - [Vitamin A](https://www.elearning.dlife.in/lds-course-notes/vitamin-a-21/) - Vitamin A - eyes and epithelliummelanin, B-carotene - hemoglobinliver. - Vit A - night blindness can be treateddry eyes/conjun - dilated broncii - recurrent diarrhea, skin condtion - frioderma - anaemia/iron deficiency, bone problems, teeth problems - chalky deposits - all because of Vit Afat-soluble - good gut needed, robust pancreas antioxidant, night vision imp of Vit - [The Randle Cycle: Understanding the Glucose-Fatty Acid Cycle](https://www.elearning.dlife.in/lds-course-notes/the-randle-cycle-understanding-the-glucose-fatty-acid-cycle-7/) - Insulin high - fat burning is switched off Fat cells are among the first to become insulin resistant. - [Liver Disease – Causes Symptoms Diagnosis & Prevention](https://www.elearning.dlife.in/lds-course-notes/liver-disease-causes-symptoms-diagnosis-prevention-8/) - Notes:Risk factor for liver disease -1.Obesity around the waist2.High Blood Pressure3. One or more abnormal cholesterol levels.4. Resistance to insulin.Factors that may increase risk of liver disease :-1.Heavy Alcohol use2. Obesity3. Type 2 diabetes.4.Tatoos or body piercing3.Injecting drugs with shared needle.4. Blood transfusion before 19925.Exposure to other peoples blood v and body fluids.6.Unprotected sex.7.Exposure to - [NAFLD – The Progression Details](https://www.elearning.dlife.in/lds-course-notes/nafld-the-progression-details-10/) - Notes:Common disorder. Accumulation of excess satin the liver who drink little or no alcohol. NAFLD has been linked with insulin resistance .When heavy alcohol use causes fat to build up in the liver this condition is called alcohol associated liver disease. More than 5% of liver weight has fat then we call it a fatty liver.Most - [Alcohol](https://www.elearning.dlife.in/lds-course-notes/alcohol-20/) - TypesPrimary: OH linked C is attached to 3 H or 2 H and 1 C (e.g. methanol, ethanol)Secondary: OH linked C is attached to 1 H and 2 CTertiary: OH linked C is attached to 3 CEthanol has caloric value of ~7 kcal/gm. Unlike carbohydrates and fats that can be stored in the body and - [Vitamins](https://www.elearning.dlife.in/lds-course-notes/vitamins-23/) - Vitamins:organic compounds. micronutrients. each organisms have diff vitamin needs. ex. humans need Vit C, dogs do not. Dogs can produce enough Vit C on their own.Vitamins/mineral - boost immune sys, support normal growth, development, help cells and organs function properly.fundamental role in cellular energy generation or metabolism. act as coenzyme and cofactors in numerous metabolic processes and - [Aerobic Energy System](https://www.elearning.dlife.in/lds-course-notes/aerobic-energy-system-17/) - Notes:AEROBIC ENERGY SYSTEM-PRODUCES a large number of ATP. THIS ENERGY SYSTEM IS USED IN OUR DAY TO DAY ACTIVITIES AND ALSO LOW-MODERATE INTENSITY EXCERCISES,WALKING,JOGGING,ENDURANCE ACTIVITIES AND CARDIOVASCULAR TRAINING THIS ENETGY SYSTEM GIVES SUSTAINABLE ATP PRODUCTION - [Krebs Cycle](https://www.elearning.dlife.in/lds-course-notes/krebs-cycle-17/) - Notes:THE KREBS CYCLE IS A SERIES OF CHEMICAL REACTIONS USED BY ALL AEROBIC ORGANISMS TO GENERATE ENERGY THROUGH THE OXIDATION OF ACETLY COA DERIVED FROM CARBS FATS AND PROTIEN THE MAIN FUNCTION OF THE KREBS CYCLE IS TO PRODUCE ELECTRON CARRIERS THAT CAN BE USED IN THE LAST STEP OF CELLULAR RESPIRATION - [Lactic Acid Energy System](https://www.elearning.dlife.in/lds-course-notes/lactic-acid-energy-system-14/) - Notes:LACTID ACID ANERGY SYSTEM ALSO KNOWN AS THE ANAEROBIC GLYCOLYSISITS THE BODYS PRIMARY SOURCE OF ENERGY FOR HIGH INTENSITY ACTIVITIES FOR ABOUT 5-60 SEC WHAT IS GLYCOLYSIS?- IT IS THE PROCESS OF BREAKING DOWN OF GLUCOSE. AS FOR THIS SYSTEM THE FUEL SOURCE IS GLYCOGEN THE CURRENT SYSTEM DELVES INTO THE ANAEROBIC SYSTEM WHICH IS A - [ATP-PC Energy System](https://www.elearning.dlife.in/lds-course-notes/atp-pc-energy-system-15/) - Notes:CREATINE - 95% OF THE BODYS CREATINE IS IN THE MUSCLES AND A SMALL AMOUNT IS IN THE BRAIN,HEART,TESTES AND PANCREASENOTE- CREATINE IS NOT A PROTIEN NEITHER AN AMINO ACID IT IS A METABOLITEOUR HUMAN BODY PRODUCES APPROX 250GMS OF ATP DAILYBUT IT RECYCLES ITS ENTIRE BODY WEIGHT IN ATP EACH DAY THROUGH CREATINE PHOSPHATECP CAN - [Thyroid Stimulating Hormone – TSH](https://www.elearning.dlife.in/lds-course-notes/thyroid-stimulating-hormone-tsh-20/) - Thyroid Stimulating Hormone - TSH: produced by pituitary gland - stimulates thyroid gland to produce thyroxine (T4) and triiodothyronine (T3) - stimulates metabolism of almost all the tissues in body.glycoprotein hormone - produced by thyrotrope cells in anterior pituitary gland - regulates endocrine function of thyroid. Endocrine organs are glands that secrete hormones.T3, T4 - needed for maintaining - [Creatine](https://www.elearning.dlife.in/lds-course-notes/creatine-21/) - Notes:CREATIN IS A MOLECULE THATS PRODUCED IN THE BODY FROM AMINO ACIDS ITS MAINLY MADE IN THE LIVER AND TO A LESSER EXTENT IN THE KIDNEYS AND PANCREASEATHLETES USE CREATINE TO ASSIST IN HIGH INTENSITY TRAINING CREATINE HELPS BODY MASS TO INCREASECREATIN IS FOR BODY BUILDERS - [Adenosine Triphosphate – ATP](https://www.elearning.dlife.in/lds-course-notes/adenosine-triphosphate-atp-18/) - Notes:ATP IS A MOLECULE IN ALL LIVING CELLS WHICH STORES AND PROVIDES ENERGY FOR VARIOUS CELLULAR PROCESSESATP IS OFTEN CALLED THE ENEERGY CURRENCY OF THE CELL BECAUSE THIS MOLECULE PLAYS A KEY ROLE IN METABOLISMSENERGY IS PRODUCED WHEN THE OUTERMOST LAYER IS BROKEN CONVERTING ATP TO ADP - [PCOS – Medical Approach For Treatment](https://www.elearning.dlife.in/lds-course-notes/pcos-medical-approach-for-treatment-9/) - Notes:Medical approach -Hormonal birth control pills, patch, shot,vaginal ring and hormone intrauterine device, for women who don't want to get pregnant.Antiandrogen medicines - These medicines block the effect of androgens and can help reduce scalp hair loss, facial and body hair growth .PCOS can cause - Miscarriage, Gestational Diabetes, Preeclampsia, Casarean section.Precautions - Loosing weight - [PCOS — Causes & Symptoms](https://www.elearning.dlife.in/lds-course-notes/pcos-causes-symptoms-11/) - Notes:Causes &. Symptoms-Genes - Studies show that many genes contribute to the condition.Insulin Resistance - Up to 70% of women with PCOs have insulin resistance meaning that their cells can't use insulin properly.Demand for insulin increases, the pancreas make more insulin to compensate.Extra insulin triggers the ovaries to produce more male hormones. Obesity is major - [PCOS – Gynecological Or Metabolic Problem?](https://www.elearning.dlife.in/lds-course-notes/pcos-gynecological-or-metabolic-problem-10/) - Notes:PCOS is a multifactorial disease and is thus a consequence of metabolic disorder, hormonal disorder and psychosocial disorders. It is extremely important to holistically treat these patients early on to help them deal with emotional stress that is often overlooked with polycystic ovary syndrome.Hyperinsulinemia is the culprit :-70% of PCOS can be tracked back to - [PCOS – Polycystic Ovarian Syndrome](https://www.elearning.dlife.in/lds-course-notes/pcos-polycystic-ovarian-syndrome-17/) - Notes: - [Somatostatin](https://www.elearning.dlife.in/lds-course-notes/somatostatin-23/) - Somatostatin: Somatostatin is a cyclic peptide well known for its strong regulatory effects throughout the body. Also known by the name of growth hormone inhibiting hormone, it is produced in many locations, which include the gastrointestinal (GI) tract, pancreas, hypothalamus, and central nervous system (CNS). Two active forms of the peptide exist, and they vary in - [20 Common Mistakes On LCHF / Keto Diet](https://www.elearning.dlife.in/lds-course-notes/20-common-mistakes-on-lchf-keto-diet-14/) - 1.Not eating Enough2.Trying to go low carb and Low Fat3.Overeating Allowed foods4.Not Counting Carbs Properly5.Missing the Sight of Proteins6. Overdoing on FATS7. Lack of Planning.8. Getting Stuck in a rut-eating the same thing every day.9 Relying on packaged Food10 Sneaky Carbs11 Couch Potatato- Get active to to achieve results12. Thinking low carbs Meaning Zero Carbs13.Expecting - [Secretin](https://www.elearning.dlife.in/lds-course-notes/secretin-13/) - secretin:peptide hormone - regulates secretions in stomach, liver, pancreas.regulates pH of duodenumpresecretin format - precursor acts on pituitary glands and kidneys too. secreted by S cells of duodenum mucosa. acts on ducts cells - release sodium bicarbonate - so pancreatic secretion becomes more alkaline. Secretin is secreted by S cells in the duodenum and affects numerous other organ systems. - [Progesterone](https://www.elearning.dlife.in/lds-course-notes/progesterone-20/) - Progesterone:Endometrial cancer is a hormone-driven cancer, with approximately 80% of endometrial cancers arising attributable to either an excess of estrogen or a lack of progesterone.Given that endometrial cancer is clearly associated with obesity, we put forth the hypothesis that a large portion of these cancers might be prevented by treatment with progesterone. Estrogen promotes endometrial cancer - [Peptide YY](https://www.elearning.dlife.in/lds-course-notes/peptide-yy-20/) - Peptide YY:isolated in 1983 - gastrointestinal hormone of 36 amino acids with tyrosine residues at both C and N terminals. structurally related to 2 other peptide hormones - pancreatic peptide and neuropeptide-Y - all belonging to PP-fold family of peptides (PP-PYY-NPY)PYY acts to reduce appetite. when injected directly into central nervoud sys - PYY is - [Oestrogen Or Estrogen](https://www.elearning.dlife.in/lds-course-notes/oestrogen-or-estrogen-19/) - Oestrogen or Estrogen:In humans, the factors that control fat distribution are partially determined by sex hormones concentrations [38]. Men, on average, have less total body fat but more central/intra-abdominal adipose tissue, whereas women tend to have more total fat that favors gluteal/femoral and subcutaneous depots. The decrease in estrogen levels in menopausal women is associated with - [Norepinephrine](https://www.elearning.dlife.in/lds-course-notes/norepinephrine-20/) - Norepinephrine: C8H11NO3also called noradrenaline or noradrenalin - stress hormone and neurotransmitter - sends signals between nerve cells.produced in inner part of adrenal gland called adrenal medulla. this also makes adrenaline (epinephrine) this along with dopamine - belong to catecholamine family.adrenal glands primarily make adrenaline and norepinephrine comes to blood from nerve endings. regulates mood and - [Melatonin](https://www.elearning.dlife.in/lds-course-notes/melatonin-23/) - Melatonin: C13H16N2O2produced by various tissues in body but pineal gland in brain is the major source - in response to darkness. regulates sleep wake cycle. produced from amino acid tryptophan - by pineal gland at night-time.night-time detected by reduced light entering eyes - optic nerve sends melatonin secretion signal to pineal gland. hormone of darkness.melatonin - [Luteinizing Hormone](https://www.elearning.dlife.in/lds-course-notes/luteinizing-hormone-13/) - Luteinizing Hormone:Luteinizing hormone (LH) is a glycoprotein hormone that is co-secreted along with follicle-stimulating hormone by the gonadotrophin cells in the adenohypophysis (anterior pituitary). Luteinizing hormone is a part of a neurological pathway comprised of the hypothalamus, the pituitary gland, and the gonads. LH release is stimulated by gonadotropin-releasing hormone (GnRH) and inhibited by estrogen in females - [Leptin](https://www.elearning.dlife.in/lds-course-notes/leptin-24/) - Leptin:peptide hormone - source of leptin production is fat tissue - white fat tissue - placenta, stomach too. more fat cells or bigger fat cells - body fat goes up, leptin goes up. obese - high leptin. insulin stimulates leptin production - almost double - quicker than fat cells making from scratch. another stimulator - cytokine - tnf-alpha from - [Insulin Resistance & Endothelial Dysfunction](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-endothelial-dysfunction-25/) - IR & Endothelial Dysfunction:Endothelium is a key element in the regulation of vascular homeostasis and its alteration can lead to the development of vascular diseases. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with potential extensive vascular lesions, involving skin vessels, renal glomeruli, cardiovascular system, brain, lung alveoli, gastrointestinal tract vessels and more.Endothelial dysregulation - [Insulin Resistance & Dyslipidemia](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-dyslipidemia-21/) - IR & Dyslipidemia:abnormal levels of lipids in blood is dyslipidemia which is:high low-density lipoproteins (LDL)low HDLhigh triglycerideshigh cholesterol - LDL and triglycerides levels.In absence of insulin resistance readings, triglycerides/HDL ratio shows insulin resistance.Triglyceride (TG)/HDL ration > 2.75 in men and > 1.65 in women -> metabolic syndrome.dyslipidemia introduced by IR and diabetes (diabetes dyslipidemia) characterized - [Insulin Resistance & Osteoarthritis](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-osteoarthritis-20/) - IR & Osteoarthritis:insulin resistance has 3 more more factors as below:hypertension, increased triglycerides, reduced HDL, increased waist circumference, elevated fasting glucose.Synovial inflammation refers to the swelling and irritation of the synovium, the lining of the joints. OA is seen in full diabetic patients as well as inulin resistance cases before actual rise in blood sugar levels.Rheumatoid Arthritis - [Insulin Resistance & Uric Acid](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-uric-acid-22/) - IR & uric acid: The anthropometric variables (weight, height and waist circumference), blood pressure and biochemical parameters were collected. The clinical characteristics of the groups were analyzed by t-test or chi-square test. Pearson's test and logistic regression were applied.The increase in serum uric acid showed a positive statistical correlation with insulin resistance and it is associated with and - [Myth: PUFA Loaded Vegetable Oils Are Better Than Saturated Fat](https://www.elearning.dlife.in/lds-course-notes/myth-pufa-loaded-vegetable-oils-are-better-than-saturated-fat-53/) - Notes: mitochondria dysfuction and DNA damange is a typical /metobalic Sydntome and dieases OxLAMS toxic c can bind to DNA and mitochondra and cell nucleus and resu;ts tp gemtic damange - [Insulin Resistance & Cardiovascular Disease](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-cardiovascular-disease-24/) - IR & cardiovascular disease:IR -> chronic hyperglycemia -> triggers oxidative stress and causes inflammatory response that leads to cell damage.IR alters systemic lipid metabolism - development of dyslipidemia > high levels of plasma triglycerides, low levels of high density lipoprotein, appearance of small dense low-density lipoproteins - atherosclerotic plaque formation.signal transduction alteration, impaired regulation of - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-86/) - digestive enzymes:amylase: mouth - [Complete Blood Count (CBC) Tests](https://www.elearning.dlife.in/lds-course-notes/complete-blood-count-cbc-tests-11/) - Notes:Measures RBCs, WBCs & platelets.Hematocrit - Proportion of blood volume thats amde up of RBCsPlatelets - No. of platelets which are essential for blood clotting.Hormone impact on CBCThyroid hormones - Hypothyroidism may result in anemiaStress hormones - Stress can elevate cortisol levels which impacts WBCs. - [Vasodilators](https://www.elearning.dlife.in/lds-course-notes/vasodilators-8/) - Notes:Medicines that dilate blood vessels allowing blood to flow more easily.Hydralazine - Works by relaxing the muscles in blood vessels to help them dilate. - [Diuretics](https://www.elearning.dlife.in/lds-course-notes/diuretics-8/) - Notes:Also called as water pills. Help the kidneys eliminate excess sale & water from body thus lowering BP - [Centrally Acting Antihypertensives](https://www.elearning.dlife.in/lds-course-notes/centrally-acting-antihypertensives-7/) - Notes:Central acting agents lower your heart rate & reduce BP. By blocking signals from your brain to nervous system that speed up your heart. - [Calcium Channel Blockers or Calcium Antagonists](https://www.elearning.dlife.in/lds-course-notes/calcium-channel-blockers-or-calcium-antagonists-8/) - Notes:Disrupt the movement of calcium through calcium channels. Some also slow the heart rate which can further lower the bp. - [Beta Blockers](https://www.elearning.dlife.in/lds-course-notes/beta-blockers-8/) - Notes:Work by blocking the effects of hormone epinephrine also known as adrenaline. They cause your heart to beat more slowly & with less force which lowers BP. - [Angiotensin II Receptor Blockers](https://www.elearning.dlife.in/lds-course-notes/angiotensin-ii-receptor-blockers-7/) - Notes:Block action of angiotensin 2 leading to enlarged or dilated blood vessels. - [Alpha Blockers](https://www.elearning.dlife.in/lds-course-notes/alpha-blockers-8/) - Notes:Work by blocking the effect of nerves in SNS - [Angiotensin Converting Enzyme Inhibitors](https://www.elearning.dlife.in/lds-course-notes/angiotensin-converting-enzyme-inhibitors-8/) - Notes:Relax blood vessels as well as decrease blood volume - [GLP1 Analogues](https://www.elearning.dlife.in/lds-course-notes/glp1-analogues-8/) - Notes:Glucagon is a hormone that causes the liver to release its stored sugar into bloodstream.Slowing glucose absorption into the bloodstream by reducing the speed at which stomach emtpies after eating - [Thiazolidinediones](https://www.elearning.dlife.in/lds-course-notes/thiazolidinediones-8/) - Notes:Decrease insulin resistance by formation of new fat cells on arms, thighs & butt. - [Sulfonylureas and Meglitinides](https://www.elearning.dlife.in/lds-course-notes/sulfonylureas-and-meglitinides-8/) - Notes:Stimulate pancreas to produce more insulin. - [Sodium-Glucose Cotransporter-2 – SGLT2 – Inhibitors](https://www.elearning.dlife.in/lds-course-notes/sodium-glucose-cotransporter-2-sglt2-inhibitors-8/) - Notes:Inhibit glucose reabsorption in kidney. - [Dipeptidyl peptidase-4 – DPP4 – Inhibitors](https://www.elearning.dlife.in/lds-course-notes/dipeptidyl-peptidase-4-dpp4-inhibitors-8/) - Notes:Supress DPP4 htat breaks down the incretin hormones - [Biguanides](https://www.elearning.dlife.in/lds-course-notes/biguanides-8/) - Notes:Prevent production of glucose in the liver, improving the body's senstivity towards insulin & reducing amount of sugar absorbed by intestines.Metformin is cheap. - [Alpha Glucosidase Inhibitors](https://www.elearning.dlife.in/lds-course-notes/alpha-glucosidase-inhibitors-9/) - Notes:Slow down digestion & absorption of carbs by blocking alpha glucosidase. This causes the blood sugar levels to peak less - [Autophagy](https://www.elearning.dlife.in/lds-course-notes/autophagy-6/) - Notes:3 typesMacrophagymicroautophagychaperone mediated autophagyCell recycles unneeded or damaged parts of itself to create new parts.Insulin generally inhibits autophagy due to activation of mtor pathway.IF triggers an autophagic response by nutrient stress activating AMPK. After 16-18 hours of fasting - [Insulin Resistance & Cancer](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-cancer-23/) - IR and cancer:high insulin and insulin resistance -> increases exocrine pancreatic cancer risk. obesity, diabetes, glucose intolerance -> pancreatic cancersmoking for long years, also one of the cause.increased exercise, no saturated fats, diet, wt loss - can reduce the riskbreast cancer - postmenopausal - over wt women get it. high cytokines in circulation - breast cancer, - [Types of Intermittent Fasting](https://www.elearning.dlife.in/lds-course-notes/types-of-intermittent-fasting-8/) - Notes:Lower % of lean body mass is lost with IF vs traditional dieting.16/8During fasting, insulin levels drop & HGH levels go up. - [The Role Of Nutrition In Human Health](https://www.elearning.dlife.in/lds-course-notes/the-role-of-nutrition-in-human-health-21/) - Notes:Immune system constantly triggered can cause chronic inflammation which is factor in diabetes, obesity and lung diseases, heart and nervous system.The food we eat can also impact our mood and stress and stress is one of the biggest enemies of good all-round health.Essential fatty acids and essential amino acids keep us healthy.Deficiency of Vitamin B12 - [Energy Pathways](https://www.elearning.dlife.in/lds-course-notes/energy-pathways-19/) - Notes:1kcal= 4.2 kilojoules[ measurement of food in the body such as kcal]ATP IS THE MOLECULAR CURRENCY FOR ENERGYMETABOLISMS IS A COMBINATION OF TWO DIFFERENT PROCESSES THAT IS -CATABOLISM AND ANABOLISMMETABOLISM IS THE SUM OF ALL CHEMICAL REACTION THAT TAKE PLACE IN A LIVING ORGANISMCATABOLISM- THE PROCESS OF BREAKING DOWN COMPLEX COMPOUNDANABOLISM- THE PROCESS OF BUILDING - [Inflammation](https://www.elearning.dlife.in/lds-course-notes/inflammation-21/) - Notes:INFLAMMATION ENABLES OUR BODY TO RECOGNIZE AND RESPOND TO INFECTION AND INJURY HAVING TOO WEAK OF AN INFLAMMATATORY RESPONSE LEAVES US PRONE TO INFECTION OR IMPAIRED HEALING BUT HAVING A SYSTEM THAT REMAINS OVER ACTIVE FOR TOO LONG PUTS US AT A RISK FOR A FORM OF CHRONIC DISEASESTHERE SHOULD BE A EXQUISITE BALANCE BETWEEN THE TWOFACTORS - [Insulin Resistance & Hypothyroidism](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-hypothyroidism-19/) - IR & hypothyroidism:thyroid has significant impact on glucose metabolism and IRhyperthyroidism: impaired glucose tolerance may be result of hepatic IRhypothyroidism: IR of peripheral tissues.normal glucose metabolism may be disrupted by deficit or excess of thyroid.IR -> T2DM and hypo and hyper-thyroidismdeep connection between hyperthyroidism and diabetes. autoimmunity - thyroid dysfunctionthyroid directly controls insulin secretion.hypothalamic pituitary thyroid - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-85/) - Notes: - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-60/) - Notes: - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-56/) - Notes: - [Timed Access & Course Completion Time](https://www.elearning.dlife.in/lds-course-notes/timed-access-course-completion-time-13/) - Notes: - [Insulin Resistance & Hypertension](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-hypertension-21/) - IR & hypertension:anabolic hormone - role in regulation of glucose, lipid homeostatis, energy storage.IR casuses, obesity, dyslipidemia, impaired glucose intolerence, hypertension.when IR happens, to keep normoglycemia, glucose uptake happens in skeletal muscles and adipocytes.since IRS1 (insulin receptor substrate 1) to uptake glucose to adipose tissues was severely diminished, the salt absorption in kidney proximal tubules - [Carbohydrates](https://www.elearning.dlife.in/lds-course-notes/carbohydrates-32/) - 3 types of dietary carbohydrates – Sugar (generally considered simple carb), Starch (complex carb), Fiber (complex carb)Sugar – sweet sugar units, which are digested quickly for immediate energy –Monosaccharides (simple sugar) – 1 sugar unit. E.g. glucose, fructose, galactose. Glucose, also called blood sugar or dextrose, is the main monosaccharide in the body. Glucose and - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-30/) - Proteins are one of the three macronutrients used as energy source. They provide 4 Kcal of energy per gm. They are essential, complex molecules that perform most of the work in cells, acting as building blocks for structure, enzymes, hormones, and immune system. They are composed of long chains of amino acids, which are joined - [Fats](https://www.elearning.dlife.in/lds-course-notes/fats-26/) - Fats and oils are composed of triglycerides that are made of 3 fatty acids (RCOOH, R being a hydrocarbon chain) and a glycerol, (CH2OH)2CHOH. Lipid is the general term, though lipids are not necessarily triglycerides. Oil normally refers to a lipid with short or unsaturated fatty acid chains (leading to lower melting point) that is - [Insulin Resistance & NAFLD](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-nafld-24/) - Insulin Resistance & NAFLD:Non alcoholic fatty liver disease- excess fat accumulation in liver of people who drink less or no alcohol. more serious condition is called nonalcoholic steatohepatitis (NASH).liver cell inflammation and diff degrees of scarring. NASH -> leads to severe liver scarring and cerrhosis.Cerrhosis - liver sustains severe substantial damage and liver cells gradually replaced - [Insulin Resistance & PCOS](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-pcos-22/) - Insulin resistance & PCOS:elevated blood sugar and insulinmyo-Inositol, d-chiro-insitol - ovaries produces lot of testosterone - skin acne, hair androgens contribute to insulin resistance in PCOS. Compared to the general population, women with polycystic ovary syndrome (PCOS) have a higher risk for diabetes.A1C ≥5.7% identified the subgroup of PCOS patients with higher insulin resistance, inadequate compensatory insulin - [Insulin Resistance & Diabetes](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-diabetes-27/) - Insulin resistance & Diabetes:types of diabetes: type 1: your immune sys destroys insulin making cells in pancreas called beta cells. in children and young people so called juvenile diabetes - need to take exogenous insulin to control blood sugar.type 1.5 LADA - latent autoimmune diabetes in adults - need to depend on exogenous insulin.type 2: MODY - [Insulin Resistance & Obesity](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-obesity-28/) - Insulin resistance and obesity:obesity: causes heart diseases, sleep-apnea, cancers, diabetes 2adipocytes are one of the most highly insulin-responsive cell typesdose of body fat has effect on insulin sensitivity. central obesity has more effect than peripheral - gluteal/subcutaneous.Adiposity refers to the accumulation of body fatobesity - exaggeration of normal adiposity - generation of excessive adipokines.insulin resistance, diabetes, - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-59/) - Notes:Pre agriculture era Proven primary food by H is meat!Evidence goes back 3 million yrs using stone age weapons discovered 2.6 million yr s oldHomo erectus species ancestors to homo sapiens (human beings) meatfruit / vegs only opts then.Agriculture evolution2.6 million humans evolved but discovered agri & started growing crops 10000 yrs ageRice 1st domesticated in southeast Asia - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-57/) - Notes: humans were ancestors of apesapelike ancestorswe share physical and behavioural traits from our apelike ancestors, this is a period of 6 million yearsFirst ;traits were bipedalism walk on 2 legs evolved over 4 million years agoother value abilities1. large complex brains2. use tools3. language capacity developed / evolved more recentlyThe past 100,000 yr humans traits like - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-55/) - Notes:Humans evolution is from Primates. over 85 million ago.various animals like chimps and apes gorillas Humans separate from chimps around 7 .5 million yrs agomany cases in afi= - [Insulin Test – Setting The Bar Right](https://www.elearning.dlife.in/lds-course-notes/insulin-test-setting-the-bar-right-20/) - INSULIN TEST - fasting insulin is the test to measure the amount of insulin in the body - to monitor abnormal insulin levels and to monitor insulin resistance. usually < 25 is the normal range defined, BUT THERE IS A PROBLEM IN THIS.Joseph Kraft Insulin Assay:limits are high for convenience of food industry. ex. healthy low fat - [Insulin](https://www.elearning.dlife.in/lds-course-notes/insulin-23/) - Insulin: C257H383N65O77S6polypeptide hormone - made by Langerhans in pancreatic beta cells. Langerhans cells (LCs) are a type of dendritic cell, which are immune cells found in the skin and other tissuescomposed on 2 proteins - A chain (21 amino acids), B chain (30 amino acids) - linked together by sulphur atoms (disulphide bridges)natural hormone - produced in - [Navigation Flow Sequence](https://www.elearning.dlife.in/lds-course-notes/navigation-flow-sequence-13/) - Notes:make notes as u go along - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-81/) - Mouth – Epiglottis (a piece of cartilage) folds over larynx (windpipe) to let food pass into esophagus and prevent choking. Saliva enzymes:Amylase – breaks starch and glycogen into smaller sugarsLipase – breaks fat into simple lipidsEsophagus – peristalsis. Lower esophagus sphincter relaxes to let food pass into stomach. The sphincter usually stays closed to not - [Heart Failure](https://www.elearning.dlife.in/lds-course-notes/heart-failure-8/) - Notes:When heart doesn't pump heart failure occurs.Insulin resistance leads to structural abnormalities in the heart, such as increased left atrial size, left ventricular mass, and alterations in transmittal velocity that can precede the diagnosis of heart failure.The development of cardiac insulin resistance may occur independently of systemic insulin resistance.Types of Heart Failure - Heart failure - [Heart Attack](https://www.elearning.dlife.in/lds-course-notes/heart-attack-10/) - Notes:A heart attackhapens when there is a sudden loss of blood supply to the heart, While heart failure is when the heart is unable to pump blood efficiently.Coronary heart disease - Coronary heart disease tends to develop over time. A waxy substance called plaque can build up inside the artery, something that we know as - [AMPK Pathway](https://www.elearning.dlife.in/lds-course-notes/ampk-pathway-19/) - Notes:mTOR PATHWAY HAS THE ADENOSINE MONOPHOSPHATE ACTIVATED PROTEIN KINASE[AMPK] PATHWAY AS ITS OPPOSING PATHWAYAMPK PLAYS A KEY ROLE AS A MASTER REGULATOR OF CELLULAR ENERGY HOMEOSTATIS IT HAS A ROLE AS A CENTRAL REGULATOR OF BOTH LIPID AND GLUCOSE METABOLISMSON SENSING LOW ENERGY AND INCOMING NUTRIENTS THE BODY ACTIVATES AMPK PATHWAY TO KEEP THE BODY RUNNING IT - [Insulin Resistance & Uric Acid](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-uric-acid-20/) - Notes:URIC ACID IS A WASTE PRODUCT FROM THE DIGESTION OF FOODS THAT CONTAIN PURINESPURINES ARE NORMALLY PRODUCED IN THE BODY AND ARE ALSO FOUND IN FOODS AND DRINKSMOST URIC ACID DISSOLVES IN BLOOD AND TRAVEL TO THE KIDNEYS AND FROM THERE IT PASSES OUT IN THE URINEIF YOUR BODY PRODUCES TOO MUCH URIC ACID OR - [Fats](https://www.elearning.dlife.in/lds-course-notes/fats-24/) - Notes:fats and oils are composed of molecules know as triglicerides that are composed of three fatty acids units linked to glycerolfats provide 9kcal of energy per gramMONOUNSATURATED FATS-oliec acids are the most common type found in 90% of in the human dietother MUFAs are palmitoleic acids[high in macademia plants] and vaacenic acid[found in human milk]MUFAs - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-20/) - Notes: GBA highlightes the connection between gastrointestinal healh[GI] and neurological functionsthere are 2 nervous system in our body CENTRAL NERVOUS SYSYTEM[made up from brain to spinal cords]PERIPHERAL NERVOUS SYSTEM[made up from nerves that branch from the spinal cords and extent to all parts of the body]ANS [AUTONOMIC NERVOUWS SYSTEM]its a devision of PNS that controls involuntary body - [Cardiac Arrhythmia](https://www.elearning.dlife.in/lds-course-notes/cardiac-arrhythmia-10/) - Notes:Abnormal heart rate or heart rhythm.Regular healthy heart rate is 60 to 100 per minute.Two powerful lower chambers called Ventricles and two powerful upper chambers called Atria also contract to help fill ventricles . But milder contraction occurs just before the ventricles contract and it is not felt in the pulse. Types of Arrhythmia :-- Tachycardia - [Incretin — GLP-1 And GIP](https://www.elearning.dlife.in/lds-course-notes/incretin-glp-1-and-gip-25/) - Intestine Secretion Insulin - INCRETINTwo primary Incretin hormones secreted on ingestion of Glucose -Gastric inhibitory polypeptide -GIPGlucagon-like peptide-1 - GLP-1GIP FUNCTIONS-1. Increases insulin secretion , causes increases in serum insulin concentrations on Glucose ingestion2. Inhibits absorpotion of water and electrolytes in small intestion3. activation and regulation of lipoprotein lipase(LPL).4. Inhibits glucagon-induced lipolysis and has an - [Cardiomyopathy](https://www.elearning.dlife.in/lds-course-notes/cardiomyopathy-10/) - Notes:Cardiomyopathy is disease of heart muscle. In most cases cardiomyopathy causes the heart muscle to become enlarged thick or rigid. The diseased heart muscle tissue is replaced with scar tissue .As cardiomyopathy horses the heart becomes weakerThe heart becomes less able to pump blood throughout the body and incapable of maintaining a normal electrical rhythm. - [Atherosclerosis](https://www.elearning.dlife.in/lds-course-notes/atherosclerosis-11/) - Notes:Pathalogical process in coronary arteries, cerebral arteries, iliac and femoral arteries and aorta that is responsible for coronary heart disease, stroke and peripherialarterial disease.Atheroscleresis is sometimes called hardening of the arteries . The terms atherosclerosis and arteriosclerosis are sometimes used interchangeably.Atherosclerosis can happen in all arteries.If one has atherosclerosis in one of your arteries, there - [Incretin — GLP-1 And GIP](https://www.elearning.dlife.in/lds-course-notes/incretin-glp-1-and-gip-24/) - Incretin - GLP-1 and GIP:glucose lowering element from gut extracts - INtestine seCRETion INsulinGastric inhibitory polypeptide (GIP), glucagon-like peptide 1 (GLP-1) - primary incretin hormones secreted from intestine on ingestion of glucose or nutrients to stimulate insulin secretion from pancreas beta cells. exert their effect by binding to specific receptors which belong to G-protein coupled - [Human Growth Hormone](https://www.elearning.dlife.in/lds-course-notes/human-growth-hormone-12/) - Human growth hormone: HGHsomatotrope interacts with growth hormone releasing hormone - > produces growth hormonewhat stimulates:high amino acids in bloodlow glucose levels in bloodlow fatty acid levels in bloodexercisehealthy stress arculate nucleus - is stimulated to produce growth hormoneGH - to liver - jack stat pathway -> IGF-1 - promote protein synthesis - open channels for - [Ghrelin](https://www.elearning.dlife.in/lds-course-notes/ghrelin-24/) - Ghrelin:was discovered after ghrelin receptors (growth hormone secretagogue type 1A or GHS-R) was determined in 1999. name is based on its role as Growth Hormone Releasing peptide with reference to Proto-Indo-European root.levels orimarily regulated by food intake. levels rise just before eating or when fasting - timing affected by normal meal routine. activates need to begin - [Glucagon](https://www.elearning.dlife.in/lds-course-notes/glucagon-30/) - Glucagon: linear peptide of 29 amino acids. with molecular weight of 3485 Da. structurally related to secretin family of peptide hormones.synthesized as proglucagon in alpha cells of pancreatic islets. Also expressed in intestinal tract as family of glucogon-like peptides enteroglucagon.functions:major role in maintaining normal concentration of glucose in blood - opposite effect if insulin i.e. glucagon - [Gastrin](https://www.elearning.dlife.in/lds-course-notes/gastrin-16/) - Gastric: peptide hormonegas gene - 17th chromosome of humanstimuli - partially digested protein, amino acid, vagal nerve stimulation,if too much HCL, then gastrin secretion is inhibited.peptide hormone secreted by G cells in gastric sntrum, duodenum and pancreas. promoting gastric acid secretion needed for digestion and mucosal growth in stomach.physiological role of gastrin:1. acid production - - [Follicle-stimulating Hormone](https://www.elearning.dlife.in/lds-course-notes/follicle-stimulating-hormone-26/) - Follicle stimulating hormone - FSH:member of glycoprotein hormone family. family also contains LH, chorionic gonadotropin (CG), thyroid stimulating hormone TSH. disulfide rich heterodimers.FSH is gonadotropin, other is luteinising hormone - both are released by pituitary into bloodstream - contains alpha and beta chain. regulates functions of both ovaries and testes. functions of FSH: essential to pubertal development - [Cortisol](https://www.elearning.dlife.in/lds-course-notes/cortisol-23/) - Cortisol: C21H30O5 - molar mass 362.460 g/molsteroid hormone produced by adrenal gland - metabolism, immune response. vital role in helping body respond to stress.when some threat comes up, chemical called adrenocorticotropic hormone (ACTH) is released in brain. this triggered adrenal gland to release cortisol and adrenaline. when used as medicine, it is known as hydrocortisone. functions - [Cholecystokinin](https://www.elearning.dlife.in/lds-course-notes/cholecystokinin-15/) - Cholecystokinin: CCKimp for gastric functionamino acid peptide type hormonesecreted from endocrine cells of duodenum and some portion of jejunum.primarily acts on pancreatic cells, also on liver, gall bladder and stomach. cck leads to release of digestive enzymes from pancreas. CCK secretion increased with fatscck acts on pancreatic cells leading to nsecretion of majority of pancreatic enzymes like - [Amylin](https://www.elearning.dlife.in/lds-course-notes/amylin-26/) - Amylin/IAPP: discovered in 1986 - approved diabetes drug pramlintide acetate37-amino acid peptide glucoregulatory - co-secreted along with insulin from pancreatic beta cells - secreted primarily in response to post-absorptive stimulation of beta cells by glucose. centrally acting, neuroendocrine hormone. provoked by ingestion of food in GI tract - for restoring blood glucose homeostasis. regulates glucose homeostasis - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-31/) - Notes:bipedalism - the ability to walk on two legs, evolved over 4 million years ago. Advanced traits including complex symbolic expression, art and elaborate cultural diversity - emerged mainly during the past 100,000 years.The commencement of agriculture and the rise of the first civilizations happened within the past 12,000 years.The first major evolutionary change in the - [Aldosterone](https://www.elearning.dlife.in/lds-course-notes/aldosterone-15/) - Aldosterone: mineralocorticoid hormone - produced by adrenal cortex in zona glomerulosa. fundamental role in regulating sodium, potassim levels, fluid balance, bp. C21H28O5molas mass: 360.450 g.mol^-1regulates sodium homeostasis to control blood volume and pressure. essential component for sodium conservation in kidneys, salivary glands, sweat glands, colon. indirectly helps to maintain pH of blood with electrolyte levels.1. maintains salt - [Adiponectin](https://www.elearning.dlife.in/lds-course-notes/adiponectin-29/) - Adiponectin: GBP-28, apM1, AdipoQ, Acrp30 - protein hormone and adipokine - involved in regulating glucose levels as well as fatty acid breakdown. produced in adipose tissue (fat cells) and in muscle and brain. it is 244-amino-acid-long-polypeptide (protein)some other hormones released from adipose tissue are:1. aromatase - sex hormone metabolism2. TNF alpha, IL-6, leptin - collectively cytokins - [Adrenaline](https://www.elearning.dlife.in/lds-course-notes/adrenaline-29/) - Adrenaline: C9H13NO3produced in medulla in adrenaline gland and some of central nervous sys's neurons. also known as epinephrine. adrenaline, noradrenaline - 2 separate but related hormones and neurotrasnmitters. in stressful situation, it is quickly released in blood sending impulses to organs to create a specific response.as drugs - epipen, adrenaclickchemically epinephrine is derived from amino acid - [Alcohol](https://www.elearning.dlife.in/lds-course-notes/alcohol-19/) - Alcohol: organic compound consisting of existing one or more hydroxyl groups i.e. OH - that is connected to carbon atom in alkyl group.3 kinds: based on group of hydroxyl and its position in attachment.primary, secondary, tertiaryEthanol - direct impact on DNA due to its metabolites named acetaldehyde, acetic acid. Methanol - more toxic than ethanol. - [Fats](https://www.elearning.dlife.in/lds-course-notes/fats-25/) - Fats:fats and oil - triglycerides (3 fatty acids linked to glycerol)RCOOH * 3 + H2C -- OH (glycerol)lipid not necessarily triglyceride. oil - lipid with short or unsaturated fatty acid chain that is liquid at room temp. fats - lipids that are solid are room temp.types of fats in food:categorized based on no. and bonding of carbon - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-31/) - Proteins: 4 calories of energy per gm. fats - 9 calories per gm except triglycerides which produce lil less.linear polymers built of monomers called amino acids. conatin wide range of functional groups: alcohols, thiols, thioethers, carboxylic acids, carboxamides.can interact with one another and other biologic macromolecules to form complex assemblies. 4 levels of protein structure:primary - amino acids - [mTOR Pathway](https://www.elearning.dlife.in/lds-course-notes/mtor-pathway-25/) - Notes:MAMMALIAN TARGET OF RAPAMYCIN- mTORmTOR pathway is a part of a complex network of cell signaling and transduction basically in easy term the role of mTOR pathway is regulating metabolism, cell growth and survival, immunity in response to different stimuli such as hormone, growth factor, nutrient - [Cardiovascular Disease – CVD](https://www.elearning.dlife.in/lds-course-notes/cardiovascular-disease-cvd-12/) - Notes: - [L Leucine](https://www.elearning.dlife.in/lds-course-notes/l-leucine-19/) - Notes:L-LEUCINE IS ONE OF THE NINE ESSENTIAL AMINO ACIDS IN HUMANS[PROVIDED WITH FOOD]LEUCINE IS IMP FOR PROTIEN SYNTHESIS AND OTHER METABOLLIC FUNCTIONS IT CONTRIBUTES TO THEREGULATION OF BLOOD-SUGAR LEVELSGROWTH AND REPAIR OF MUSCLES AND BONE TISUUEGROWTH HORMONE PRODUCTIONWOUND HEALINGTHIS AMINO ACID IS ALSO KNOWN FOR PREVENTING THE BREAKDOWN OF MUSCLE PROTIENS CAUSED BY INJURY OR STRESS - [Dehydration & Sodium Importance in Sports](https://www.elearning.dlife.in/lds-course-notes/dehydration-sodium-importance-in-sports-18/) - Notes:DEHYDRATION means -muscle breakdown and lossfaster aging due to faster breakdown of all tissuesa drop in immunity and energy levelshigh risk of muscle cramps during exerciseSODIUM-sweat takes electrolytes with it on its way out of pores.generally you can loose between half a liter to four liter of sweat per hour during a workout.a liter of - [Diabetes Diagnosis & Management](https://www.elearning.dlife.in/lds-course-notes/diabetes-diagnosis-management-8/) - Notes:General Symptoms of diabetes -- Excessive thirst and hunger- Frequent urination- drowsiness or fatigue- dry, itchyskin- blurry vision- Slow healing wounds- numbness in hands- pins and needles feeling- bad dental health like bleeding gums, cavities.Standard Diagnosis :-1. Glycated hemoglobin ( A1C ) test .a.Doesnt require fastingb.it measures the percentage blood sugar.c. An A1c level of - [Diabetic Complications](https://www.elearning.dlife.in/lds-course-notes/diabetic-complications-11/) - Notes:1. Type 1 diabetes results from auto immune beta - cell destruction in the pancreas and is characterised by a complete lack of insulin production.2. Type 2 which develops when there is an abnormally increased resistance to the action of insulin and the body cannot produce enough insulin to overcome the resistance.3.Gestational Diabetes ;- Happens - [Gestational Diabetes](https://www.elearning.dlife.in/lds-course-notes/gestational-diabetes-10/) - Notes:Gestational diabetes mellitus is diabetes or high blood sugar level that develops during pregnancy. It occurs in about 4% of all pregnancies. Gestational diabetes usually is diagnosed in the later stages of pregnancy and often occurs in women who have no prior history of diabetes.Who are at risk ? Some degree of insulin resistance and impaired - [Carbohydrates](https://www.elearning.dlife.in/lds-course-notes/carbohydrates-33/) - Carbohydrates: CHOhave carbon, hydrogen and oxygen atoms. found in both healthy and unhealthy foods. one of the 3 macronutrients. 3 types of dietary carbs:sugars - sweet, short-chain carbs. glucose, fructose, galactose, sucrose. sugar with 1 molecule or 1 sugar called monosaccharides, sugar with 2 molecules or 2 monosaccharides are disaccharides. both are simple sugars.glucose - blood sugar or - [Type 2 Diabetes](https://www.elearning.dlife.in/lds-course-notes/type-2-diabetes-8/) - Notes:The most common type of diabetes is a disease that occurs when our blood glucose also called blood sugar is too high. Blood glucose is our main source of energy and comes mainly from food we eat.Insulin a hormone made by the pancreas helps glucose get in to our cells to be used for energy. - [Type 1 Diabetes](https://www.elearning.dlife.in/lds-course-notes/type-1-diabetes-12/) - Notes: Diabetes occurs when blood sugar is too high. Blood glucose is main energy derived from ingested carbs and sugar. Insulin hormone made by pancreas helps the glucose in blood to get in to the cells to be used as energy. Glucagon works with insulin to control blood glucose. - [Diabetes](https://www.elearning.dlife.in/lds-course-notes/diabetes-13/) - Notes: Blood Sugar Regulation :- Regulation of blood glucose is largely done thru the endocrine hormones of pancreas, a balance of hormones achieved by a negative feedback loop.The hormones of the pancreas that affect blood glucose include insulin, glucagon, somatostatin, and amylin.Insulin lowers blood Glucose levels, whereas glucagon elevates blood glucose levels. After we gave - [Myth: Carbohydrates Are Essential](https://www.elearning.dlife.in/lds-course-notes/myth-carbohydrates-are-essential-41/) - Aerobic glucose metabolism – requires oxygen, yields CO2, water and a net of 32-38 ATP molecules per glucose molecule, making it highly efficient. But it’s a slow process so used for sustained, lower-intensity activities.Anaerobic glucose metabolism – does not require oxygen, produces lactic acid from pyruvate (glucose turns to pyruvate first) and a net of - [Body Fat Measurement](https://www.elearning.dlife.in/lds-course-notes/body-fat-measurement-16/) - Body fat measurement:bad body composition means more fat and less muscle. Indians - high carb, bad fat and low protein. Densitometry: human body in 2 compartments - fat (FM), fat-free (FFM) - more dense than fat tissue. based on assumption that fat has density constant of 0.9kg/L and fat-free component has density of 1.1kg/L. Densitometry measures body mass and volume - [Introduction To Anthropometry](https://www.elearning.dlife.in/lds-course-notes/introduction-to-anthropometry-23/) - Introduction to Anthropometry:study of human body measurements - to understand physical variations among humans. use in genetic research and workplace ergonomics. provides insight into study of human fossils and can help understand evolution better.Invented by Alphonse Bertillon - french policeman - end of 19th century. weight, height, body mass index (BMI), body circumferences (arm, waist, hip - [Food Intolerance & Allergy](https://www.elearning.dlife.in/lds-course-notes/food-intolerance-allergy-16/) - Food intolerance & allergy:intolerance - sensitivities - not life-threatening, by and large. reaction after eating/drinking some food - not an immune response. occurs when indigestion of some food happens, not able to break down food. few reasons: not having right enzymes to digest, reactions to food additives like MSG, sensitivity to caffein/chemicals, sensitivity to sugars - [Foods: The ‘Yes’, ‘May’ & ‘Never’ List](https://www.elearning.dlife.in/lds-course-notes/foods-the-yes-may-never-list-24/) - Foods: the yes, may and never listsugar names:Agave nectar, barbados sugar, barley malt, beet sugar, blackstrap molasses, brown rice syrup, brown sugar, buttered syrup, cane juice crystals, cane sugar, caramel, carob syrup, castor sugar, confectioner's sugar, corn syrup, corn syrup sloids, crystalline fructose, date sugar, demerara sugar, dextran, dextrose, diastatic malt, diatase, ethyl maltol, evaporated - [The Role Of Nutrition In Human Health](https://www.elearning.dlife.in/lds-course-notes/the-role-of-nutrition-in-human-health-20/) - role of nutrition in human health:food is medicine by Hippocrates (2500 years ago) - father of western medicine.immune sys is constantly triggered - can create chronic inflammation - actor in diabetes, obesity, lung diseases, heart and nervous sys.essential fatty acids and amino acids keep us healthy. illness stemmed from inadequate nutrients and bad eating habits.lack - [Dysbiosis](https://www.elearning.dlife.in/lds-course-notes/dysbiosis-28/) - Dysbiosis: altered microbiotanon like receptor family - sensing microorganismsNLRP - pyrine domain - ASC -> caspase-1 do inflammasomes modulate intestinal microbiota? NLRP6, ASC, caspase1 to IL-18 regulate microflora.they disturb gut. epithelial barrier - mucus layer keeps microorganisms out - except pathogens -non-alcoholic fatty liver disease - leads to cirrhosis and cancer.liver is the first organ affected by - [Quizzes and Assignments](https://www.elearning.dlife.in/lds-course-notes/quizzes-and-assignments-9/) - Notes:Must read tab - [Human Growth Hormone](https://www.elearning.dlife.in/lds-course-notes/human-growth-hormone-11/) - HGH - somatotropinheightreduce weightintermittent fasting 16 hoursHIITquality sleep - [Body Fat Measurement](https://www.elearning.dlife.in/lds-course-notes/body-fat-measurement-15/) - Body fat ratingRisky (high body fat) – M >30%, W >40%Excess fat – M 21-30%, W 31-40%Moderately Lean – M 13-20%, W 23-30%Lean – M 9-12%, W 19-22% (excellent for health and longevity)Ultra Lean – M 5-8%, W 15-18% (often found in elite athletes)Risky (low body fat) – M - [Sugar & Carb Addiction](https://www.elearning.dlife.in/lds-course-notes/sugar-carb-addiction-26/) - Sugar and carb addiction: starch/grains - glucose45 % glucose and 55 % fructose in corn syrup and also in coca cola100 gm of sugar vs 100 gm of protein vs 100 gm of fat - has different hormonal effects/responses from body.insulin resistance -> cancer of endometriumsugar - most palatable and addictive food. sugar shares several characteristics - [The Origin Of Carbohydrate Restriction In Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-origin-of-carbohydrate-restriction-in-chronic-diseases-12/) - The origin of carb restriction in chronic diseases:fatty protein foods for diabetics - meat, fish, cheese, butter, olive oil, eggs and poultry. No starchy foods, sugar, saccharine foods - Saccharin is a zero-calorie, artificial sweetener used in a variety of food and drink products, including diet sodas, candies, jams, and baked goods.discovery of insulin in 1922. - [Introduction To Anthropometry](https://www.elearning.dlife.in/lds-course-notes/introduction-to-anthropometry-22/) - Ideal Body Weight (IBW) - more applicable for sedentary person than an actively trained individual where Body Fat % is more applicable.Male: Height (cms) - 100 (range: +/- 5 kgs)Female: (Height (cms) - 100) - 10% (range: +/- 5 kgs)Body Mass Index (BMI) - Weight (kgs) / Height (m)2 - not a good health indicator, shows - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-84/) - Notes:1. The digestive tract, from the mouth to the anus, is 10 meters long2. - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-58/) - Notes:1. Human evolved 2.6 million years ago2. Humans exclusively consumed meat3. Meat, Fruits and Vegetables were the only option available4. rice was first domesticated 10,000 t0 14,000 years ago5. wheat, maize, and rice most produced grains.6. Wheat has more protiens than other grains7. 99.99% of our genetic pattern formed before the onset of agriculture8. The - [Water & Electrolytes](https://www.elearning.dlife.in/lds-course-notes/water-electrolytes-16/) - Notes:WATER IS AN ESSENTIAL NUTRIENT WE CAN SURVIVE SEVERAL WEEKS WITHOUT FOOD BUT ONLY A FEW DAYS WITHOUT WATEREVERY SYSTEM IN THE BODY FROM CELLS AND TISUUE TO VITAL ORGANS REQUIRES WATER TO FUNCTIONIMP FUNCTIONS OF WATER-HYDRATIONPROTECTIONWASTE REMOVALDIGESTIONREGULATION OF BODY TEMPERATUREELECTROLYTES- ARE INVOLVED IN MANY ESSENTIAL PROCESSES IN OUR BODYTHEY PLAY A ROLE IN CONDUCTING NERVOUS - [Food Intolerance & Allergy](https://www.elearning.dlife.in/lds-course-notes/food-intolerance-allergy-15/) - Food intolerance is a chemical reaction that some people have after eating/drinking certain foods, whereas, food allergy is an overreaction of the immune system when it sees food as an invader.Food intolerance reactions are dose dependent, may not occur until a certain amount. Food intolerance happens when something in a food irritates the digestive system or - [Foods: The ‘Yes’, ‘May’ & ‘Never’ List](https://www.elearning.dlife.in/lds-course-notes/foods-the-yes-may-never-list-23/) - Many people rely on processed foods (contain added sugar) for meals and snacks. Due to this, added sugars account for up to 17% of total calorie intake in adults and up to 14% in children in the US.Packaged foods are loaded with fructose, which increases hunger for food more than glucose. Fructose and glucose are - [TOFI – Thin Outside Fat Inside – Obesity](https://www.elearning.dlife.in/lds-course-notes/tofi-thin-outside-fat-inside-obesity-11/) - Notes:Obesity by definition is an accumulation of more than ideally required fat.But depending upon the location of the excess adipose tissue one can visually appear to be skinny or fat.Thin outside fat inside :- TOFI is used to describe lean individuals with a disproportionate amount of fat stored I their abdomen . They have more - [Obesity & Cardiovascular Disease](https://www.elearning.dlife.in/lds-course-notes/obesity-cardiovascular-disease-11/) - Obesity is one of the leading causes of elevated cardiovascular mortality and morbidity. The prevalence is increasing in both developed and developing countries.WHO data - 39% of the global population above 18 years of age are overweight and of these 13% are obese.Number of studies have demonstrated a relationship between obesity and cardio vascular diseases. - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-55/) - Notes:1. Evolution over a six million years 2. Bipedalism: Over 4 million years3. Symbolic expression, art, and Elaborate cultural diversity over the past 100,000 years4. Humans are primates (Homo sapiens)5. Agriculture and first civilisation within past 12,000 yearsDietary Evolution:1. Humans were more into a meat diet with seasonal fruits and some roots/tubers2. With agricultural practices, we - [Myth: Dietary Fat Causes Weight Gain](https://www.elearning.dlife.in/lds-course-notes/myth-dietary-fat-causes-weight-gain-20/) - why counting calories is stupid? human body does not have idea on what calorie is.obesity - not a calorie problem. is a hormone problem - insulin resistance issue.those who ate nuts more frequently were leaner than the infrequent nut eaters. All nuts except chestnuts are high in fats. moderate-high fat diet sustained wt loss more - [Myth: PUFA Loaded Vegetable Oils Are Better Than Saturated Fat](https://www.elearning.dlife.in/lds-course-notes/myth-pufa-loaded-vegetable-oils-are-better-than-saturated-fat-52/) - Omega 6 loaded poly unsaturated fatty acids (PUFA) vegetable oils - thought to be great - more than one bond in the carbon chain - missing hydrogen bonds like in saturated fats - are liquid at room temp - unstable and prone to oxidation - worst thing to consume.Rancidification is the chemical process where fats and - [Myth: Saturated Fat Causes Heart Disease](https://www.elearning.dlife.in/lds-course-notes/myth-saturated-fat-causes-heart-disease-32/) - Myth: saturated fat causes heart diseaseMinnesota Coronary Experiment (MCE):low carb - reduces blood triglycerides, HDL improves. total and LDL cholesterol decreases. Insulin decreases s0 Insulin sensitivity increases. improvements on total cholesterol/HDL ratiohigh intake of dairy fat - low central obesitylow intake of dairy fat - high central obesity.cholesterol is not bad - is needed.lipoprotein - - [Dysbiosis](https://www.elearning.dlife.in/lds-course-notes/dysbiosis-27/) - A balanced gut microbiome performs crucial functions for human health includingmetabolic functions – digestion, nutrient absorption, synthesis of essential nutrients and vitamins such as SCFA, amino acids, vitamin K and B-group vitamins.immune function – protects against harmful bacteria and pathogensDysbiosis is an imbalance in the body’s microbial communities, particularly in the gut, characterized by a loss - [The Role of Exercise](https://www.elearning.dlife.in/lds-course-notes/the-role-of-exercise-7/) - Notes: - [Myth: Proteins Cause Kidney Damage](https://www.elearning.dlife.in/lds-course-notes/myth-proteins-cause-kidney-damage-21/) - Recommended dietary allowance (RDA) for protein is 0.8 per kg of body weight (BW)for body weight of 70 kg - lower end protein should be 90 gm and higher end protein should be 140 gmhigh protein diet - popular for weight loss due to effects of protein induced satiety to control hunger. - [Myth: Plant Based Diets Are The Best](https://www.elearning.dlife.in/lds-course-notes/myth-plant-based-diets-are-the-best-32/) - ovo-vegetarians - eat eggs.lacto-vegetarians - eat dairy but no eggs.ovo-lacto-vegetarians - eat both eggs and dairy.pescatarians - eat fish but no other animalsvegans - eat nothings derived from animals - entirely plant based - many nutrients are gone missing or deficient in diet. Deficit in many nutrients like iodine, iron, zinc, taurine, Vit A, D, - [Importance Of Protein & Fat In Sports](https://www.elearning.dlife.in/lds-course-notes/importance-of-protein-fat-in-sports-9/) - Notes:FAT - FAT IS CALORIE DENSE AND PROVIDES A SUSTAINED SOURCE OF ENERGY AND HAS MINIMAL IMPACT ON INSULINIF THE MAJORITY OF YOUR CALORIE IS COMING FROM FAT THE BODY BECOMES MORE EFFICIENT IN BURNING FAT AND USING ITS OWN STORED FAT FOR FUELWITH CARB-CENTRIC DIET ELEVATED INSULIN PREVENTS THE USE OF STORED BODY FAT - [Three Pillars Of Fitness](https://www.elearning.dlife.in/lds-course-notes/three-pillars-of-fitness-13/) - Notes:THE THREE PILLARS OF FITNESS EXCERCISENUTRITION SLEEP [ SLEEP IS THE NEGLECTED PILLAR OF ALL]A GOOD QUALITY SLEEP IS MUST FOR A GOOD HEALTH - [Glucagon](https://www.elearning.dlife.in/lds-course-notes/glucagon-29/) - Notes:linear peptide29 amino acids increases blood glucose levelsblood sugar low means level of glucagon in blood is high - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-26/) - Autonomic NS (ANS)a)Sympethetic NS (SNS) - fight/flightb)Parasympethetic NS (ANS) - rest/digest Heart RateSNS inc it, PNS dec itDigestionSNS inhibits, PNS enhancesPupil SizeSNS dilates it, PNS contricts itBronchial tubesSNS dilates, PNS contractsUrinary sysSNS inhibits, PNS promotesBlood flowSNS shifts blood to muscle, PNS directs it to digestive organs----------------------ENS - second brainembedded deep in lining of GI track from - [Sugar & Carb Addiction](https://www.elearning.dlife.in/lds-course-notes/sugar-carb-addiction-25/) - Insulin crosses the blood-brain barrier and acts on CNS regions, including the mesolimbic system, a brain pathway involved in reward and motivation. Insulin modulates the mesolimbic system to regulate glucose homeostasis and the "value" of food cues, influencing motivation for food intake by influencing dopamine activity. Insulin suppresses dopamine levels, thereby helps to reduce the - [The Role Of Nutrition In Human Health](https://www.elearning.dlife.in/lds-course-notes/the-role-of-nutrition-in-human-health-19/) - Vitamin B12 deficiency leads to anemia (fatigue, pale skin, shortness of breath, dizziness, and headaches) and neurological conditions (nerve damage, tingling/numbness in the limbs, muscle weakness, dementia, delirium, catatonia, hallucinations, difficulty with coordination/balance, memory problems, confusion, and mood changes like irritability, depression, apathy). - [Myth: Carbohydrates Are Essential](https://www.elearning.dlife.in/lds-course-notes/myth-carbohydrates-are-essential-42/) - macronutrients - carbs (non-essential), protein and fats (essential).human body can make its own glucose whatever little is needed - no external carbs as such.micronutrients - vitamins, minerals and food supplementsMetabolic profile of diff parts of human body:1. brain: glucose is virtually the sole fuel for brain except durting prolonged starvation. So, by giving low-carb food, - [Diet Heart Hypothesis](https://www.elearning.dlife.in/lds-course-notes/diet-heart-hypothesis-26/) - Diet heart hypothesis: reducing dietary saturated fats reduce serum cholesterol - this has become public health policy now.7 countries showed correlation between saturdated fats and cardiovascular mortality. But ignored 15 countries that did not show any correlation.Dr. keys did not give the actual report. marketing weapon of vegetable oil industry.SATURATED FAT CAUSES HEART DISEASE IS - [American Diabetes Assn – Low Carb & Very Low Carb Diet For Diabetes](https://www.elearning.dlife.in/lds-course-notes/american-diabetes-assn-low-carb-very-low-carb-diet-for-diabetes-18/) - ADA - US based nonprofit. diabetic complications - cardiovascular disease, amputation of limbs, lost eyesight, end-stage renal disease.low carb - significant A1C reduction, weight loss, lowered blood pressure, lower triglycerides and increase in HDL.LCHF - 20% of total calories can be carbs or max 100 gm of total intake can be carbs - whichever is - [Proteins](https://www.elearning.dlife.in/lds-course-notes/proteins-29/) - Notes:protiens also provide 4kcal of energy per gram protiens are the most versatile macromolecule in living system and play a huge role in the biological processesTHERE ARE 4 LEVELS OF PROTIEN:PRIMARY STRUCTURE[AMINO ACIDS ARE LINKED BY PEPTIDE BONDS TO FORM POLYPEPTIDE CHAINS][SEQUENCE OF A CHANGE OF AMINO ACIDS]SECONDARY STRUCTURE[AMINO ACIDS\POLYPEPTIDE CHAINS CAN FOLD INTO A REPEATING - [Carbohydrates](https://www.elearning.dlife.in/lds-course-notes/carbohydrates-28/) - Notes:carbs are made up of three molecules carbon,hydrogen and oxygen atomsdietary carbs can be split into three categories-SUGAR,STARCH AND FIBERSfructose is found in fruits,honey,corn syrupgalactose is not generally prsent in nature it combines with glucose to form a double sugar called lactoselactose is found in all dairy products and it gives the milk a sweet - [Low Carb Diet](https://www.elearning.dlife.in/lds-course-notes/low-carb-diet-12/) - Notes: - [The Latest Eat Lancet](https://www.elearning.dlife.in/lds-course-notes/the-latest-eat-lancet-22/) - Eat lancet diet 0 ==- push grains, fruits, sugar, veggeis, and vilify animal protein and fat.all climate change is related to population growth not what we eat.Lancet + EAT - non-governmentasl advocacy in Norway - eatforum.org - more than 30 world-leading scientists across globe who share goal of developing recommendations for a sustainable, healthy diet - [How The Dietary Guidelines Evolved](https://www.elearning.dlife.in/lds-course-notes/how-the-dietary-guidelines-evolved-12/) - Notes: - [The Introduction to Dietary Guidelines.](https://www.elearning.dlife.in/lds-course-notes/the-introduction-to-dietary-guidelines-19/) - Introduction to dietary guidelines:Department of health and human services (HHS) and department of agriculture (USDA)1st guideline:low fat -less meat, poultry, fish, high carb - fruits, veggies and grains, low sugar, slow saturated fat, low cholesterol - less eggs, low salt, non-flat instead of whole milk. - [Dietary Guidelines Myths & Facts](https://www.elearning.dlife.in/lds-course-notes/dietary-guidelines-myths-facts-27/) - HHS and USDA - review, update and publish dietary guidelines every 5 years.dietary guidelines- grain and carb-centric.veganism - leads to malnutrition.CardioDiabesity - cardiovascular disease, diabetes, obesity - influenced by Insuline resistance. - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-25/) - git-brain axis (GBA) - connection between GI health and neurological functions.consists of ENS (second brain), CNS (thru the vegus nerve), thru chemical mediators like hormones and neurotransmitters.significant role of gut microbiota in influencing mental health, cognitive functions and neurological disorders.Anatomy and physiology of gut-brain axis: Neural pathways: primary neural connection via vagus nerve - signals in - [Myth: PUFA Loaded Vegetable Oils Are Better Than Saturated Fat](https://www.elearning.dlife.in/lds-course-notes/myth-pufa-loaded-vegetable-oils-are-better-than-saturated-fat-51/) - Both MUFA and PUFA have an inherent problem of rancidity. Humans can easily detect rancidity of MUFA (e.g. stale fish), which is not that harmful. But, humans cannot detect rancidity of PUFA (e.g. stale bakery which are loaded with PUFA). Rancidity/oxidation of omega-6 FA (accelerated by heat, air, light) produces worst form of toxins called - [Complete Blood Count (CBC) Tests](https://www.elearning.dlife.in/lds-course-notes/complete-blood-count-cbc-tests-10/) - Notes: estradiol levels are lowest during menstruation, which can lead to lower red blood cell counts and hemoglobin levels due to menstrual blood loss. This fluctuation can cause variations in iron levels, potentially leading to temporary anemia.Progesterone peaks during the luteal phase of the menstrual cycle, which can influence fluid retention and thus affect hemoglobin concentration - [Protease](https://www.elearning.dlife.in/lds-course-notes/protease-15/) - Protease/proteinase/peptidase - to catalyze hydrolysis of peptide bonds that link amino acids together in a poly peptide chain.helps in development, differentiation, cell migration, immunity, wound healing and cell death.Proteases - post translationally modifying enzymes. they catalyse a functionally irreversible reaction - amide bond hydrolysis. they breakdown protein. Made by animals, plants, bacteria and fungi. Also - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-20/) - digestion of carbs - breaking complex polysaccharides into simpler absorable forms. In mouth and pancreas - first enzyme to interact with food.salivary - Ptyalin - secreted by salivary glands - digestion of starch in mouth - activity continues briefly in stomach. In mouth, starch converts to maltose and dextrins. Initial digestion continues until food reaches - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-23/) - Lipase - enzyme that catalyzes hydrolysis of triglycerides into free fatty acids and glycerol - role in lipid metabolism & digestion. produced in pancreas and also in mouth, stomach and intestines - essential for absorption of fats. also helps in energy metabolism and production of biofuels.types:1. pancreatic - primary secreted by pancreas and passed to - [The Current Situation](https://www.elearning.dlife.in/lds-course-notes/the-current-situation-24/) - hyper-platable (cheap and widely available and hijack our brain to eat more and more) and ultra processed food is getting consumed - root causePCOS, central obesity, type 2 diabetes, hypertension, heart attacks at young age.all these diseases are in epidemic proportion in India.Pop a pill culture - Pills control only symptoms, not cure root cause - [20 Common Mistakes On LCHF / Keto Diet](https://www.elearning.dlife.in/lds-course-notes/20-common-mistakes-on-lchf-keto-diet-13/) - Notes:COMMON MISTAKE ON A LOW CARB DIET-NOT EATING ENOUGHTRYING TO GO LOW CARB AND LOW FATOVER EATING ALLOWED FOODSNOT COUNTING CARBS PROPERLYMISSING THE SIGHT OF PROTIENSOVERDOING ON FATSLACK OF PLANNING GETTING STUCK IN A RUTRELYING ON PACKAGED FOODSNEAKY CARBSCOUCH POTATOTHINKING LOW CARB MEANS ZERO CARBEXPECTING THE DRAMATIC WEIGHT LOSS TO CONTINUEDOING INTENSE WORKOUT ON YOUR FIRST - [The Rise of Modern Chronic Diseases](https://www.elearning.dlife.in/lds-course-notes/the-rise-of-modern-chronic-diseases-22/) - chronic condition - physical or mental condition lasting more than a year which causes functional restrictions or requires ongoing monitoring/treatment. - 50% in USA have chronic conditionsex. cancer, diabetes, hypertension, stroke, heart disease, respiratory diseases, arthritis, obesity & oral diseases.cardiovascular - top reasonobesity, diabetes - follows - appear early in life now and to many - [Current Treatment Options For NAFL and NASH](https://www.elearning.dlife.in/lds-course-notes/current-treatment-options-for-nafl-and-nash-8/) - Notes:50% of T2d Patients have NAfLD - [Liver Disease – Causes Symptoms Diagnosis & Prevention](https://www.elearning.dlife.in/lds-course-notes/liver-disease-causes-symptoms-diagnosis-prevention-7/) - Notes:Liver infection - Hepatitis viruses - Hep A, B & CAutoimmune diseasesLiver disease symptoms - Yello skin & eyes, itchy skin, dark urine - [Myth: Saturated Fat Causes Heart Disease](https://www.elearning.dlife.in/lds-course-notes/myth-saturated-fat-causes-heart-disease-31/) - Dietary saturated fat is very different from fat stored after De novo lipogenesis (DNL) – metabolic process (most active in liver / adipose tissues) in which body synthesizes its own fatty acids from non-fat substrates, primarily carbs. With excess of carbs, liver converts these into fatty acids, which are then combined with glycerol to form - [NAFLD – The Progression Details](https://www.elearning.dlife.in/lds-course-notes/nafld-the-progression-details-9/) - Notes:Accumulation of excess fat in liver2 types of NAFLDNAFLNASH - [Myth: Plant Based Diets Are The Best](https://www.elearning.dlife.in/lds-course-notes/myth-plant-based-diets-are-the-best-31/) - Move to plant based diets risks worsening nutrient deficiencyIodineIronZinc – functions include immune system health, cell growth and repair, DNA and proteins synthesis, sense of taste and smell, wound healing, development during growth periods, carbohydrates breakdown, and acting as co-factor for ~100 enzymes.Choline – critical to brain health, particularly during fetal development. Also influences liver - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-83/) - mouth to anus - muscular tube up to 10 meters long - digestive organs - mouth, esophagus, stomach, small and large intestines and anus - liver, pancreas and gallbladder - solid organs of digestive system.large reservoir of microbes like bacteria (gut flora - help in digestion) - in large intestine and in rest of digestive - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-57/) - primary food - meat - archaelogists found evidence over 3 MYA with the help of stone age weapons.homo erectus > homo sapiens - meat eaters - fruits, veggies and meat were only optionshumans evolved around 2.6 MYA but agriculture started around 10k YA.Rice in southeast asia 10-14k YA. all came from China. wheat - started after - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-54/) - ape like ancestors - physical and behsvioral traits evolved over apprx. 6 million years.bipedalism - over 4 million years agohominins early diet - included omnivorous diet like fruits, leavesmbarks, insects and meat. 2.6 MYA - expansion to this diet happened - meat and marow of small/large animals.modern chronic diseases: diabetes, hypertension, atherosclerosis, alzheimer's, auto-immune disease, - [PCOS & Obesity – The Connection](https://www.elearning.dlife.in/lds-course-notes/pcos-obesity-the-connection-9/) - Notes:Obese women tend to be more hyperandrogenic - [PCOS — Causes & Symptoms](https://www.elearning.dlife.in/lds-course-notes/pcos-causes-symptoms-10/) - Notes:Symptoms of excess androgens - Excess hair growth on face, arms, back etc. Thinning hair on head, AcneIR Symtpoms - Weight gain, trouble sleeping, darkened skin around neck - [PCOS – Polycystic Ovarian Syndrome](https://www.elearning.dlife.in/lds-course-notes/pcos-polycystic-ovarian-syndrome-16/) - Notes:Enlarged ovaries with multiple cystsRotterdam criteria for diagnosis>12 follicles measuring 2-9 mm in dimeter in each ovaryHigh endrogens4 typesinsulin-resistance - Most common - high insulin levels prevent ovulation & trigger ovaries to create testosterone post-pillinflammatoryadrenal pcosPCOS - leading cause of infertility in women - [Obesity & Hypertension](https://www.elearning.dlife.in/lds-course-notes/obesity-hypertension-9/) - Hypertension is common chronic disease. Measured in millimetres of mercury.Systolic Pressure - Maximum pressure within the large arteries when the heart muscles contracts to propel blood through the bodyDiastolic - Pressure describes the lowest pressure within the large arteries during heart muscle relaxation between beating or refilling.Changes in blood pressure are made in order to - [Obesity & Diabetes](https://www.elearning.dlife.in/lds-course-notes/obesity-diabetes-12/) - Obesity and Type I diabetes :-Diabetes is a chronic disorder that can alter carbohydrate, protein and fat metabolism. It is caused by the absence of insulin secretion due to either the progressive or marked inability of the B-langerhans islet cells of the pancreas to produce insulin or due to defect in insulin uptake in the - [Myth: Proteins Cause Kidney Damage](https://www.elearning.dlife.in/lds-course-notes/myth-proteins-cause-kidney-damage-20/) - Healthy, sedentary adults, not trying to lose weight - optimal daily protein intake 1.2 g/kg to 1.8 g/kg body weight - higher intake doesn't meaningfully benefit body composition. - [Obesity & Autoimmune Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-autoimmune-disorder-9/) - Obesity might affect the function of our immune system and play a major role in the development of autoimmune diseases. In the last decades, autoimmune diseases have experienced dramatic increase in western countries. The involvement of environmental factors is strongly suspected to explain this rise. Obesity and Autoimmune Disease :-Indeed the fat tissue has been found - [Gastrin](https://www.elearning.dlife.in/lds-course-notes/gastrin-15/) - Notes: - [Obesity Is A Metabolic Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-is-a-metabolic-disorder-15/) - Obesity is an enlargement of adipose tissue to store to store excess energy intake. To handle excess energy adipose tissue expands by increasing adipocyte size (hypertrophy) and number (hyperplasia ).Obesity is actually the way the human body protects itself from the scourges and ravages of carbs/sugar. The problem with obesity actually starts to begin when - [Diet Heart Hypothesis](https://www.elearning.dlife.in/lds-course-notes/diet-heart-hypothesis-25/) - Naturally occurring trans fats present in meat/milk of ruminant animals are called “ruminant trans fats.” It resembles those found in partially hydrogenated vegetable oils and share the common formula. However, there is a double bond on a different position – this subtle difference is believed to render it less harmful. - [Gut Brain Axis](https://www.elearning.dlife.in/lds-course-notes/gut-brain-axis-24/) - The Gut-Brain Axis (GBA) is the 2-way communication system linking GI tract and CNS (central nervous system) intricately. This intricate connection influences functions ranging from mood and emotions to digestion and immunity. Functions and impact –Mood/behavior – gut health is linked to anxiety, depression and other psychiatric conditions.Stress response – the hypothalamic-pituitary-adrenal (HPA) axis, the - [Carbohydrates](https://www.elearning.dlife.in/lds-course-notes/carbohydrates-31/) - Notes: carbohydrates are one of the three basic micronutrients Dietary carbohydrates : sugar,starch,fibreSugar - [Heart Attack](https://www.elearning.dlife.in/lds-course-notes/heart-attack-9/) - Notes:Heart Attack - Sudden loss of blood supply to the heartHeart failure - When heart is unable to pump blood efficiently - [dLife Case Story – Atrial Fibrillation (AFib) & Hypertension](https://www.elearning.dlife.in/lds-course-notes/dlife-case-story-atrial-fibrillation-afib-hypertension/) - Notes:doctors advice protocol -ambiguous - [Cardiac Arrhythmia](https://www.elearning.dlife.in/lds-course-notes/cardiac-arrhythmia-9/) - Notes:Tachycardia >100bpmBradycardia 400 bpmAtril flutterIR is a risk factor for atrial fibrillation - [Cardiomyopathy](https://www.elearning.dlife.in/lds-course-notes/cardiomyopathy-9/) - Notes:Heart muscle becomes enlarged/thick or rigid.3 typesDilated - DCMHypertrophicRestrictiveDiabetic cardiomyopathy - IR, T2DSymptoms - Shortness of breath, fatigue, swelling in feet, chest paid - [Alpha Lipoic Acid](https://www.elearning.dlife.in/lds-course-notes/alpha-lipoic-acid-23/) - Notes:ALA -yeast spinach brocolli potatoes organ meat liver kidney tomatoes green peas, rice branantioxidant-300 -600 mgcontra in thyroid cofactor of 5 enzyme system-citric acid cyclewater fat solublelower bp, sugar..promotes removal of fats in musclesreduces DM retinopathyreduces risk of alzheimers - [Insulin Resistance, Lipotoxicity & Energy Toxicity](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-lipotoxicity-energy-toxicity-6/) - Notes:Energy Toxicity refers to metabolic state characterised by the accumulation of excess energy primarily stored as triglycerides in muscles and liver cells. As cells become overload with energy, they may resist further energy storage leading to diminished response to insulin which is the hormone responsible for signalling energy storage. Lipotoxicity and energy toxicity are terms - [Adipose Tissue](https://www.elearning.dlife.in/lds-course-notes/adipose-tissue-16/) - Notes:Adipose tissue is a lipid storing type of loose connective tissue. Also called as fat tissue, adipose is composed primarily of adipose cells or adipocytes. While adipose tissue can be found in a number of places in the body, it is found primarily beneath skin. Adipose is also located between muscles and around Internationall organs, - [PCOS – Polycystic Ovarian Syndrome](https://www.elearning.dlife.in/lds-course-notes/pcos-polycystic-ovarian-syndrome-15/) - Inositol prevents Insulin Resistant PCOS but most effective is LCH - [The Atkins Diet](https://www.elearning.dlife.in/lds-course-notes/the-atkins-diet-17/) - Notes:THE ATKINS DIET IS ALSO A LOW CARB DIET WHICH INVOLVES 4 PHASES THIS DIET HELPS WITH WEIGHT LOSS AND DIABETES MANAGEMENTTHERE ARE FOUR PHASES IN THIS DIET-INDUCTION - RESTRICTING CARBS TO 20GMS OER DAYBALANCINGTUNINGMAINTENANACE - [Ketogenic Diet](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-19/) - Notes:FIVE VARIATION OF KETO DIET-CLASSIC KETO- 6% PROTEIN 4% CARB 90% FATMODIFIED KETO- 10% PROTEIN 35 CARB 87% FATMCT KETO- 10% PROTEIN 17% CARB 73% FATMODIFIED ATKINS KETO- 30% PROTEIN 5% CARB 65% FATLOW GLYCEMIC INDEX RATIO- 30% PROTEIN 10% CARB 60% FATINTERMITTENT FASTING - [Metabolic Disorder — Current Indian Data](https://www.elearning.dlife.in/lds-course-notes/metabolic-disorder-current-indian-data-6/) - Notes:Few Metabolic Disorders - Obesity, Insulin Resistance, Hypertension, Polycystic Ovary Syndrome.1.Obesity - Obesity and Central Obesity are prevalent in India, posting significant health Challenge. 40% of adults are obese or overweight. Central Obesity - excess abdominal fat, is concerning, affecting20 to 50% of the adult population. This form of obesity is strongly associated with metabolic - [Protease](https://www.elearning.dlife.in/lds-course-notes/protease-14/) - Protease (PR) / Proteinase / Peptidase (a group of proteolytic enzymes) – Catalyzes irreversible hydrolysis of proteins (breaks peptide bonds that link amino acids together in a polypeptide chain) into amino acids. Because of irreversible nature, protease activity is tightly regulated at various levels. Proteases occur in all organisms – animals, plants and microbes (bacteria, - [Cardiovascular Disease – CVD](https://www.elearning.dlife.in/lds-course-notes/cardiovascular-disease-cvd-11/) - Notes:Coronary Artery Disease(CAD) - Caused by atherosclerosis in coronary arteries which carry blood to heart. Most common cause of heart attacks. - [LCHF Diet](https://www.elearning.dlife.in/lds-course-notes/lchf-diet-19/) - Notes:normally the livers glycogen storage capacity is around 120gms NON-FIBER CHO SPIKES THE INSULIN HARDEST AND FAT THE LOWEST SO THE ENTIRE PREMISE OF A LOW CARB DIET IS TO LIMIT CHO TARGET PROTIEN AND USE FAT AS THE LEVERin the ketogenic diet the body is primarily in fat burning mode on the contrary in low fat diet - [Diabetic Complications](https://www.elearning.dlife.in/lds-course-notes/diabetic-complications-10/) - Notes:Microvascular complicationsInflammation & higher hsCRPDiabetic neuropathy - Nerve DamageDiabetic nephropathy - End stage neural diseaseDiabetic retinopathy - Damages retina's blood vesselsMacrovascular complicationsChronic ulcers that often fail to healDKA - Lifethreatning - buildup of acids in blood when blood sugar is too high for too long - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-19/) - Catalyzes hydrolysis of carbs (breaks glycosidic bonds) into simple sugars and ensures body utilizes carbs for energy. Amylase activity is relatively low in infants (newborns ~18% serum amylase activity that in adults), reflecting diet composition (milk-based), increases with age and introduction of solid foods.In healthy adults, pancreatic amylase (P-AMY) accounts for ~40-50% of total amylase - [Type 2 Diabetes](https://www.elearning.dlife.in/lds-course-notes/type-2-diabetes-7/) - Notes:Also classified into Type2 & Type 2 MODY(Maturity onset diabetes of the young)MODY limits the body's ability to produce insulin but is different from juvenile T1D. Primarily genetic - [Type 1 Diabetes](https://www.elearning.dlife.in/lds-course-notes/type-1-diabetes-11/) - Notes:T1D - Pancreas stop making insulin as body's immune system which normally kills infection, attacks & destroys the cells in pancreas which makes insulin. T1D people need insulin daily to stay alive.T1D in children is also known as juvenile diabetesType 1.5D (LADA)Risk factors for T1D - Faily history, geneticsSymptoms - Increased thirst, urination, increasd hunger, - [Diabetes](https://www.elearning.dlife.in/lds-course-notes/diabetes-12/) - Standard non-diabetic ideal blood sugar range-FBS -70 mg/dL to 90mg/dL2 hr PPBS - 120mg/dL max1hr PPBS - 140mg/dL maxA1C- 5.6% - [Lipase](https://www.elearning.dlife.in/lds-course-notes/lipase-22/) - Notes:Lipase is a crucial enzyme that catalyzes the hydrolysis of triglycerides into free fattly acids and glycerol.This is produced in the pancreas but also secreted by the mouth, stomach and intesines making it essential for the digestion and absortion of dietary fats. - [LIPID Peroxidation & Neurological Disorders](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-neurological-disorders-8/) - Notes:Lipid peroxidation is a critical process in the pathogenesis of various neurological disorders, by oxidative degradation of lipids, particularly polyunsaturated fatty acids. This process causes significant cellular damage and contributes to neurodegeration.Association with specific neurological disorders:-The brains high oxygen consumption, abundant polyunsaturated fatty acids and relatively low antioxidant defences make itparticularlyvulnerable to oxidative damage. Lipid - [LIPID Peroxidation](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-10/) - Notes:Lipid Peroxidation is complex biochemical process that leads to the oxidative degradation of lipids, particularly polyunsaturated fatty acids. This process is significant both in biological systems and food science, as it contributes to cellular damage and rancidity in fats. Undertanding lipid peroxidation involves examining its mechanisms, products, implications for health and potential protective strategies.Mechanisms of - [Vitamin A](https://www.elearning.dlife.in/lds-course-notes/vitamin-a-20/) - Notes:C20H300. - [FODMAP Diet](https://www.elearning.dlife.in/lds-course-notes/fodmap-diet-8/) - Notes:FODMAP- FERMENTABLE OLIGOSACCHARIDES DISACCHARIDES MONOSACCHARIDES AND POLYOLSA GRP OF SHORT CHAIN CARBS THAT CAN BE POORLY ABSORBED IN THE SAMLL INTESTINE LEADING TO GASTROINTESTINAL DISCOMFORTTHE FOODMAP DIET IS NOT A CURE BUT A MANAGEMENT STRATEGY FOR THOSE WITH IBS OR SIMILAR DIGESTIVE ISSUESOLIGO - FOUND IN WHEAT ONIONS AND GARLIC DISACC - PRIMARILY LACTOSE FOUND IN - [South Beach Diet](https://www.elearning.dlife.in/lds-course-notes/south-beach-diet-16/) - Notes:THIS DIET MAINLY FOCUSES ON HOW TO LOOSE WEIGHT - [Obesity & Hypertension](https://www.elearning.dlife.in/lds-course-notes/obesity-hypertension-8/) - Notes:BMI Overweight : 25.9 - 29Obesity BMI>30Systolic pressure - Max pressure within large artieries when heart muscle contractsDiastolic pressure - Lowest pressure within large arteries during heart muscle relaxation.Normal - - [LIPID Peroxidation & Diabetes](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-diabetes-8/) - Notes:There is a distinct correlation between diminished antioxidant activity within cells and markedly elevated levels of lipid peroxides in diabetic patients. There is urgent need to further understand pathological relationships between high level of lipid peroxidation products and Type 2 Diabetes.Role pf Lipid Peroxidation in Diabetes :-1. Pancreatic Beta -Cell Dysfunction : ROS and lipid - [LIPID Peroxidation & Cardiovascular Disease (CVD)](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-cardiovascular-disease-cvd-9/) - Notes:Lipid peroxidation is a biochemical process involving the oxidative degradation of lipids, leading to the formation of reactive oxygen species and various byproducts that can significantly impact cardio vascular health. This process plays a crucial role in the development and progression of cardiovascular diseases particularly atherosclerosis .Lipid peroxidtion is intricately linked to the pathogenesis of - [Obesity & Cardiovascular Disease](https://www.elearning.dlife.in/lds-course-notes/obesity-cardiovascular-disease-10/) - Notes:Pro inflammatory cytokines produced by adipose tissue can induce cardiac dysfunction & promote plaque formationA 10kg rise in body weight increases the risk of coronary artery disease by 12% along with a rise in BP - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-82/) - Notes: Digestive tract begins at the mouth and ends at the anus. muscular tube upto 10 meters long with digestive organs --mouth, esophagus, stomack, small intestine, alrge intestine and anus.The liver, pancreas and gallbladder are the solid organs of the digestive system.the small intestine ahs three parts:Duodenum, jejunum and ileumLarge intestine encludes appendix, cecum, colon - [Obesity & Autoimmune Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-autoimmune-disorder-8/) - Notes:IL-6 Cytokine is involved in inflammation, immunoregulation, macrophages etc. - [Obesity Inflammation & Comorbidities](https://www.elearning.dlife.in/lds-course-notes/obesity-inflammation-comorbidities-10/) - Notes:Larger fat cells start to leak pro-inflammatory cytokines. Chronic low grade inflammation.Leads to high inflammation markers like HSCRPMHO - Metabolically Healthy Obese - Less visceral fat & larger number of smaller fat cells as weight gain is due to hyperplasia rather than hypertrophy. - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-56/) - Notes: Primary food consumed by humans was meat.Meat, fruits and vegetables were the only option available back then.Rice was first domesticated and raised agriculturally in southeast asiaWheat is the leading source of vegetable protien in human food; higher protein conent than other major cereals, maize and riceEgyptian were the first to make bread out of - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-40/) - Notes:Human evolution is gradual process of change over a period of approximately 6 millionn years from apelike ancestors.Humans are primates. Homo sapiens are closely related to the apes another group of primate species.meat and marrow= Calorie dense resourcdes with essential amino acids n micro nutrientsaquatic fauna=ricd in nutrients needed for brain growth*animal products help to - [Human Evolution](https://www.elearning.dlife.in/lds-course-notes/human-evolution-54/) - Notes:Human evolved in Africa4 stages of human evolutionfirst between four and seven million years ago walked upright on tow legssecond stage around 4 million years agoThird around 2.7 million years ago fouth stage between 1.8 and 2.5 million y ears ago who used stone tools and had brain about size of a chimpanzee - [Obesity Is A Metabolic Disorder](https://www.elearning.dlife.in/lds-course-notes/obesity-is-a-metabolic-disorder-14/) - Notes:Obesity is enlargement of adipose tissue to store excess energy intake. Adipose tissue expands by increasing adipocyte size(hypertrophy) & number(hyperplasia)Hypertropic obesity - Android fat distribution - mainly around buttocks, abdomen, chest, shoulder etc. Often associated with glucose intolerance, hypertension & CVD - [Quizzes and Assignments](https://www.elearning.dlife.in/lds-course-notes/quizzes-and-assignments-7/) - Notes: There will be quiz and assignments throughout the course and mostly auto graded except specifically mentioned graded by instructorsScores will be added in final scoreCertificate in hard copy only, sent by courierType of quiz1. Single choice from given option2. Multiple choices from given options3. Sorting4. Matching5. Fill in the blanks6. Assessment7. Essay type ( uploads - [DASH Diet](https://www.elearning.dlife.in/lds-course-notes/dash-diet-18/) - Notes: - [Iron](https://www.elearning.dlife.in/lds-course-notes/iron-18/) - Notes:iron is a mineral that is naturally present in some foods and added to some foodsIRON IS AN ESSENTIAL COMPONENT OF HEMOGLOBIN[RED BLOOD CELSS] PROTIENT THAT TRANSFERS OXYGEN FROM LUNGS TO THE TISSUES IRON SUPPORTS MUSCLE METABOLISM AND HEALTHY CONNECTIVE TISSUESIRON IS ALSO NECESSSARY FOR-PHYSICAL GROWTH NEUROLOGICAL DEVELOPMENTCELLULAR FUNCTIONINGSYNTHESIS OF SOME HORMONES - [Insulin Resistance & Hypertension](https://www.elearning.dlife.in/lds-course-notes/insulin-resistance-hypertension-20/) - Notes:hyperinsulenemia leads to more secreation of aldosterone which leads to more water retention which causes hyperinsulenemiatoo much sodium puts too much water into our blood which increases our blood volume which leads to high blood pressureactually too much blood volume puts and streches our blood vessels and it also puts pressure on our heart to - [Adipose Tissue](https://www.elearning.dlife.in/lds-course-notes/adipose-tissue-15/) - Notes:Adipose tissue also called as fat tissue. Found beneath the skin.Energy stored as fat in adipose tissue is used as fuel after energy from carbs is used upWAT - Energy storageBAT - Highest number of growth factors & cytokines are produced here, Heat productionIF & low carb keto diets help in transforming WAT to BAT - [Collagen](https://www.elearning.dlife.in/lds-course-notes/collagen-17/) - Notes:collagen is the main structural protein its one of the major building blocks of bones skin muscle tendons and ligament collagen is also found in many other body part including blood vessels corneas and teeth you can think of it as glue that holds all these things togetherthere are 16 types of collagen the four main type are - [BCAA](https://www.elearning.dlife.in/lds-course-notes/bcaa-21/) - Notes:BCAA- BRANCHED CHAIN AMINO ACIDS BCAA COMPRISES OF AROUND 35% OF OUR BODIES MUSCLE PROTIENTHEY ARE IMP CUZ THEY ARE NOT PRODUCED IN OUR BODY AND WE HAVE TO GET THEM THROUGH FOOD AND WORKOUT SUPPLEMENTSLIKE OTHER AMINO ACIDS THEY ARE BUILDING BLOCKS OF PROTIENSSUPPLEMENTING WITH BCAA HELPS PRERVE YOUR STORES OF GLYCOGEN= THE PRIMARY FUE; - [N-Acetylcysteine](https://www.elearning.dlife.in/lds-course-notes/n-acetylcysteine-23/) - Notes:N-ACETYLCYSTEINE[ NAC] IS THE SUPPLEMENT FORM OF CYSTEINE PROPONETS CLAIM THAT TAKING NAC SUPP CAN PROTECT AGAINST A PLETHORA OF HEALTH CONCERNS SUCH AS-RESPIRATORY DISEASELIVER DISEASEPSYCHIATRIC DISEASEDIABETESCERTAIN CANCERCHEMICAL DEPENDENCY - [L Proline](https://www.elearning.dlife.in/lds-course-notes/l-proline-17/) - Notes:L-PROLINE IS A MAJOR AMINO ACID FOUND IN CARTILAGE AND IS IMPORTANT FOR MAINTAINING YOUTHFUL SKIN AS WELL AS REPAIR OF MUSCLE, CONNECTIVE TISSUE , AND SKIN DAMAGE IT IS ALSO ESSENTIAL FOR IMMUNE SYSTEM AND FOR THE NECESSARY BALANCE OF THIS FORMULAIT IS AN ESSENTIAL COMPONENT OF COLLAGEN AND IS IMPORTANT FOR THE PROPER FUNCTIONING - [L Lysine](https://www.elearning.dlife.in/lds-course-notes/l-lysine-18/) - Notes:lysine is an amino acid that our body cannot synthesis on its ownsome biological functions of lysine include-serving as a building block of proteinhistone modification[ effects gene expression]provides structure to collagenregulation of calcium levelsprimary source of lysine is animal products such as meat dairy LOW LEVELS OF LYSINE HAVE BEEN FOUND IN PATIENTS WITH-PARKINSONSHYPOTHYROIDISMSKIDNEY DISEASEASTHAMADEPRESSION - [L Citrulline](https://www.elearning.dlife.in/lds-course-notes/l-citrulline-17/) - Notes:CITRULLINE IS PRODUCED IN THE HUMAN BODY AS A BYPRODUCT OF THE ENZYMATIC PRODUCTION OF NITRIC OXIDE FROM THE AMINO ACID ARGIRINE WITHIN THE HUMAN BODY CITRULLINE IS MADE IN THE UREA CYCLETHERE ARE TWO FORMS OF CITRULLINE-L-CITRULLINE - SIMPLE CIT NOTHING ELSECITRULLINE MALATE- THIS REFERS TO CITRULINE AND ANOTHER COMPOUND MALATE WHICH IS IMP FOR - [Glucosamine, Chondroitin, MSM Plus Hyaluronic Acid](https://www.elearning.dlife.in/lds-course-notes/glucosamine-chondroitin-msm-plus-hyaluronic-acid-14/) - Notes: for osteoarthritis the main cause is insulin resistance so in addition to taking care of insulin resistance which appears to a root cause of this disordercertain supplements can aid faster relief of pain and swellingGLUCOSAMINE- THE GLUCOSAMINE IN YOUR BODY HELPS KEEP UP THE HEALTH OF YOUR CARTILAGEIS A NATURAL CHEMICAL COMPOUND IN TOUR BODY IT - [Cinnamon](https://www.elearning.dlife.in/lds-course-notes/cinnamon-17/) - Notes:CINNAMON BENEFITS-IS LOADED WITH POWERFUL ANTIOXIDATANTSANTIOXIDANT HAVE ANTI-INFLAMMATORY EFFECTS WHICH HELP LOWER YOUR RISK OF DISEASEREDUCES RISK FACTORS FOR HEART DISEASE INCLUDING CHOLESTROL TRIGLYCERIDES AND BLOOD PRESSUREINCREASE SENSITIVITY TO HORMONE INSULINREDUCE FBS LEVELS HAVING ANTI DIABETIC EFFECTREDUCE INFECTIONS AND HELP FIGHT TOOTH DECAY AND BAD BREATHSIDE EFFECTS OF CINNAMON-TOO MUCH MAY INCREASE LIVER TOXICITYMOUTH SORESCAUSES - [Casein](https://www.elearning.dlife.in/lds-course-notes/casein-18/) - Notes:CASEIN IS A PROTIEN FOUND IN MILK AND DIARY PRODUCTSCONSUMING CASEIN BEFORE BED HELPS WITH MUSCLES BONES TEETHS CONSUMING CASEIN EVERYDAY IS VERY GOOD FOR OUR HEALTH AND MUSCLEPEOPLE CAN CONSUME 1-2 SCOOPS OF CASEIN PROTIEN MIXED POWDER WITH WATER YOU CAN GET PLENTY OF CASEIN FROM MILK NATURAL YOUGURT AND CHEESE - [Alpha Lipoic Acid](https://www.elearning.dlife.in/lds-course-notes/alpha-lipoic-acid-22/) - Notes:ALPHA LIPOIC ACID IS MADE IN ANIMALS NORMALLY AND IS ESSENTIAL FOR AEROBIC METABOLISMALA IS PRESENT IN-YEAST SPINACHBROCCOLIPOTATOESORGANS MEAT SUCH AS LIVER OR KIDNEYSBENEFITS OF TAKING ALPHA LIPOIC ACID-ALA IS FOUND TO BE HELPFUL WITH WEIGHT LOSSALA HAS BECOME POPULAR AS A POTENTIAL AID FOR DIABETETS AS IT HELPS TO LOWER BLOOD SUGAR LEVELS IN BOTH - [Vitamins](https://www.elearning.dlife.in/lds-course-notes/vitamins-22/) - Notes: - [Whey Protein](https://www.elearning.dlife.in/lds-course-notes/whey-protein-17/) - Notes:MILK CONTAINS TWO PROTIENS THAT ARE WHEY AND CASEIN WHEY CONTAINS ALL 9 ESSENTAIL AMINO ACIDITS ALSO LOW IN LACTOSETYPES OF WHEY PROTIEN-WPCWPIHWP - [Silymarin / Milk Thistle](https://www.elearning.dlife.in/lds-course-notes/silymarin-milk-thistle-18/) - Notes:silymarin is a flavonoid derived from SILYBUM MARIANUM it is the most commonly used medication for liver diseases - [Resistant Starch](https://www.elearning.dlife.in/lds-course-notes/resistant-starch-17/) - Notes:RESISTANCE STARCH IS A TYPE OF CARBOHYDRATE THAT IS NOT DIGESTED IN THE SMALL INTESTINE AND TRAVELS TO THE LARGE INTESTINE WHERE IT IS FERMENTED BY THE BACTERIA FEEDING THE GOOD BACTERIA IN THE GUTTHERE ARE FIVE DIFFERENT TYPES OF RESISTANCE STARCH-TYPE 1 - found in grains legumes seeds and resists digestion its bound within - [Omega 3 Fatty Acids](https://www.elearning.dlife.in/lds-course-notes/omega-3-fatty-acids-19/) - Notes:omega- 3 fats are a key family of polyunsaturated fatsEICODSAPENTAENOIC ACID-[EPA] AND DOCOSAHEXAENOIC ACID[ DHA] - COMES FROM FISH SO THEY ARE SOMETIMES CALLED AS MARINE OMEGA 3ALPHA LINOLENIC ACID [ ALA] IS FOUND IN-VEGETABLESNUTSFLAX SEEEDSOME ANIMAL FATthe human body generally uses ALA for energy TAKING OMEGA 3 FATS-THEY ARE AN INTEGRAL PART OF CELL MEMBRANE - [Test And Numbers & CAC Score](https://www.elearning.dlife.in/lds-course-notes/test-and-numbers-cac-score-14/) - Notes:LIPID PROFILE TEST - Name of the profile/Panel that lab uses to bundle standard test for cholesterol numbers. It is also named as - Coronary risk panel, Lipid profile,Fasting Lipid panel,Non Fasting Lipid Panel,Cholestrol Panel and Lipid test.This test is done to assess ones risk developing cardiovascular disease, to monitor treatment of unhealthy lipid levels. - [Adenosine Triphosphate – ATP](https://www.elearning.dlife.in/lds-course-notes/adenosine-triphosphate-atp-17/) - Notes: - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-79/) - Notes: Large intestine - absorbs water from the chyme to make it into stool. The bacteria in the large intestine break down the remaining nutrients and make Vitamin K. - [Background And Current Status](https://www.elearning.dlife.in/lds-course-notes/background-and-current-status-8/) - Notes:Notes:Myths about cholesterol:-Dietary cholesterol has little relation with serum cholesterol. In case of Hyper responders, high cholesterol food raises blood cholesterol levels. However this is more of genetics and even in them, the ldl/hdl ratio doesn't go out of whack.High quality of studies have shown tat dietary cholesterol is not associated with an increase risk - [MCT Oils](https://www.elearning.dlife.in/lds-course-notes/mct-oils-19/) - Notes:MCT OILS- MEDIUM CHAIN TRIGLYCERIDESMCT OIL IS A DIETARY SUPPLEMENT MADE UP OF MCT FATSWHICH ARE THE FATS THAT CAN BE FOUND IN COCONUT OIL PALM KERNEL OIL AND DAIRY PRODUCTSMCT OIL IS USUALLY USED BY PEOPLE WHO WANNA LOSE WEIGHT AND BOOST THIER ENDURANCE DURING A WORKOUTMCTS PROVIDE 10% FEWER CALORIES THAN LCTS[ LONG - [L Theanine](https://www.elearning.dlife.in/lds-course-notes/l-theanine-18/) - Notes:L-THEANINE IS AN AMINO ACID THAT IS FOUND IN TEE LEAVES BENEFITS OF TAKING THEANINE-REDUCES STRESS AND ANXIETYINCREASED FOCUSBETTER IMMUNITYINTERACTION WITH OTHER DRUGS-MEDICATION USED TO TREAT HIGH BLOOD PRESSURESTIMULANT MEDICATION - [Cholesterol & Its Functions](https://www.elearning.dlife.in/lds-course-notes/cholesterol-its-functions-15/) - Notes:Cholestrol is organic compound which is required by body as building block for cell membrane and for hormones like estrogen and testosterone. We may associate cholesterol with fatty foods, but most of the waxy substance is made by the liver and rest comes from dietary sources like meat, poultry eggs, fish and dairy products. foods - [Vitamins](https://www.elearning.dlife.in/lds-course-notes/vitamins-21/) - Notes:B1.. glucose utilisation B2-iron metabolism krebs cycle B3...DNA repair .. energy.. cholesterol control B5-Steroid based hormone .. cholesterol.neurotransmitterB6-protein met - [High Intensity Interval Training – HIIT](https://www.elearning.dlife.in/lds-course-notes/high-intensity-interval-training-hiit-7/) - Notes:HIIT is a type of interval training exercise. it incorporates several rounds that alternate between several nibnutes of high intensity movements to significantly increase the heart rate to at least 80% of ones maximum heart rate. followed by short periods of Lower intensity movements. Interval training was first introduced in the 1950s as a higher - [Iron](https://www.elearning.dlife.in/lds-course-notes/iron-15/) - Notes:supplements - heme and non hemeplant FE - non hemeanimal FE - both heme and non heme3-4 gm of elemntal iron in adults is in Hbremianing iron stored in ferritin or hemosiderin (degradation product of ferritin) in liver, spleen and bone marrow, also in myoglobin in musclesTransferrin binds with iron and transprts it through bodyHepcidin- - [Diet Heart Hypothesis](https://www.elearning.dlife.in/lds-course-notes/diet-heart-hypothesis-24/) - Notes:Ancel keys study, stating dietary fat causes heart issues was based on 6 countries with varied eating habits such as no meat during festival in chile and use of margarine in countries like US - [High Intensity Interval Training – HIIT](https://www.elearning.dlife.in/lds-course-notes/high-intensity-interval-training-hiit-6/) - Notes:next - [Metabolic Disorder — Current Indian Data](https://www.elearning.dlife.in/lds-course-notes/metabolic-disorder-current-indian-data-5/) - Notes:IR is a common feature in both obesity & PCOS contributing to T2D & CVD - [Cholesterol & Its Functions](https://www.elearning.dlife.in/lds-course-notes/cholesterol-its-functions-13/) - Notes:Cholestrol acts as a building block for cell membranes & for hormones like estrogen & testosterone.Most of it's made by liver & rest comes from dietary sources like meat, eggs, fish etc. Plant foods have no cholestrol.Cholestrol levels are regulated by liver.Most ingested cholestrol is poorly abosrbed by gut.It's carried by lipo-proteins in the bloodLDL - [PCOS – Polycystic Ovarian Syndrome](https://www.elearning.dlife.in/lds-course-notes/pcos-polycystic-ovarian-syndrome-14/) - Notes:1. Insulin-resistance PCOSThis is the most common type of PCOS. This type of PCOS is caused by smoking, sugar, pollution, and trans fat. In this, high levels of insulin prevent ovulation and trigger the ovaries to create testosterone. To prevent insulin resistance PCOS you can take inositol, but most important would be drastic dietary changes — - [Biceps Variation 1](https://www.elearning.dlife.in/lds-course-notes/biceps-variation-1-2/) - Notes:- Least important but most performed in gyms.- Provides temporary pump and gratification.- Hypertrophy workout but helps develop lagging muscles. - [Lat Pull Down](https://www.elearning.dlife.in/lds-course-notes/lat-pull-down-2/) - Notes:- movement similar to pull ups- Easier movement compared to pull ups.- Hypertrophy exercise working on Lattissmus Doors. - [Bent Over Row](https://www.elearning.dlife.in/lds-course-notes/bent-over-row-2/) - Notes:- Compound movement- Works on back muscles.- Trapezius, Rhomboids,Lats,Forearms and biceps.- Staple exercise in pull workout for back and strength development. - [Dead Lift](https://www.elearning.dlife.in/lds-course-notes/dead-lift-3/) - Notes:-Deadlift has most carry over effecting day to day life.- Requires to lift dead object from ground.- As we age this simple task becomes difficult.- Deadlift is compound movement.- Hamstrings, Glutes,Lower Back, Trapezius, Rhomboids, Lattismus Dorsi- Safest exercise if done with correct form/technique. - [Pull Ups](https://www.elearning.dlife.in/lds-course-notes/pull-ups-4/) - Notes:Basically, pulling own body weight against gravity. Pulling up many times from floor. This ability is weakened as one ages , hence pull ups are important to teach ones body to handle its own weight. Major muscles engaged - Latismus Doris, Biceps and forearms. - [Pull Exercise](https://www.elearning.dlife.in/lds-course-notes/pull-exercise-3/) - Notes:When human being consumes its species appropriate diet, human reaches optimal health. This results in positives changes physiologically and psychologically. One of changes in the visor and vitality of body. Vigor and vitality can be taken to next optilevel. - [Tricep Variation 1](https://www.elearning.dlife.in/lds-course-notes/tricep-variation-1/) - Notes:Strong Triceps are huge benefit.Helps in increasing overall strength of upper body pushing exercise.Trained on push days.Bench pressOverhead press. We can add two variations to isolate and fatigue the muscle. - [Shoulder Press](https://www.elearning.dlife.in/lds-course-notes/shoulder-press-2/) - Notes:The ability to lift a heavy object over our head is considered the showcase of strength and overhead press is just that. Lifting of Barbell or dumbbell over shoulders with the help of deltoids and triceps. - [Bench Press](https://www.elearning.dlife.in/lds-course-notes/bench-press-3/) - Notes:Deadlift, squat and bench press are the trinity when it comes to strength building compound exercises. A bench press challenges our upper body pushing strength .The pectoral muscles, the front deltoids and tricep are majorly involved in this lift. - [Squats](https://www.elearning.dlife.in/lds-course-notes/squats-5/) - Notes:Squats is sitting down as much as we can go and exploding up.Squats work on Quadriceps muscles, gluteal muscles, hamstrings and calves together. - [Push Exercise](https://www.elearning.dlife.in/lds-course-notes/push-exercise-2/) - Notes:Day 1 Push- Squats : 3 x 12 - Lunges : 3 x 15- Bench Press : 3 x 15- Bench : 3 x 15- Tricep Variation 1 - 3 x 15- Tricep Variation 2 - 3 x 15>Day 2 Cardio - [Anabolic Resistance](https://www.elearning.dlife.in/lds-course-notes/anabolic-resistance-8/) - Notes:Adequate quantity and quality of muscle mass are vital for overall health and function. In addition to its role of converting chemical energy to mechanical work, skeletal muscle is a major disposal site for blood glucose and fatty acids. It is a significant contributor to the basal metabolic rate. Skeletal muscle is the only appreciable - [L-Carnitine](https://www.elearning.dlife.in/lds-course-notes/l-carnitine-17/) - Notes:. L-carnitine is a chemical that is made in the human brain, liver, and kidneys. It helps the body turn fat into energy. L-carnitine is important for heart and brain function, muscle movement, and many other body processes. - [Excess Post-exercise Oxygen Consumption (EPOC)](https://www.elearning.dlife.in/lds-course-notes/excess-post-exercise-oxygen-consumption-epoc-6/) - Notes:EPOC is bodys response to exercise where it requires additional oxygen to:1.Replenish energy stores ( ATP,Phospho creatine).2. Repair tissues.3.Remove lactate.3.Restore oxygen levels in blood and muscles.4.Elevate body temperature back to normal5.Manage hormonal adjustments post exercise.Factors Influencing EPOC :-1. Exercise Intensity - Higher intensity leads to higher EPOC due to increased oxygen debt.2.Exercise Duration - Longer - [LIPID Peroxidation & Diabetes](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-diabetes-7/) - Notes:Lipid peroxidation complicates diabetes viaPancreatic Beta Cell dysfunction which reduces insulin secretion - [Inositol](https://www.elearning.dlife.in/lds-course-notes/inositol-17/) - Notes:inositol is a sugar that is abundant in the brain and other mammalian tissueit mediates cell signal transduction in response to variety of hormones neurotransmitters and growth factors and also participates in osmoregulation[balance of water and salt in our body]it is a sugar alcohol with half the sweetness of sucrose[table sugar]it is naturally made kidneys - [Magnesium](https://www.elearning.dlife.in/lds-course-notes/magnesium-24/) - Notes:magnesium is a very vital mineral in the body it is essential for maintaining healthy MUSCELS NERVES BONES BLOOD SUGAR LEVELS ETCVIT D IS A VERY CRUCIAL MINERAL AND IS USED IN MANY BODILY FUNCTIONS - [LIPID Peroxidation & Cardiovascular Disease (CVD)](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-cardiovascular-disease-cvd-8/) - Notes:Atheroscelerosis - Accumulation of oxidized LDL within arterial walls. PUFA-> Lipid Peroxidation -> Advanced lipoxidation end products -> Atherosclerotic plaque - [LIPID Peroxidation](https://www.elearning.dlife.in/lds-course-notes/lipid-peroxidation-9/) - Notes:Complex biochemical process that leads to oxidative degradation of lipids esp. PUFA contributing to cellular damage & rancidity in fats.3 stages - Initiation, Propagation & TerminationLeads to formation of malondialdehyde (MDA) & acrolein which cause damage to cells & tissues.MDA - Biomarker for lipid peroxidationLeads to Cellular Damage, Chronic Diseases & Aging.Ferroptosis - Iron dependent - [Muscle Gain](https://www.elearning.dlife.in/lds-course-notes/muscle-gain-9/) - Notes:Always consider LBM for fat loss and also for muscle gain if an individual is within ideal weight range but carries fat and has less visible muscles.An athlete who wants to build more muscles and improve his athletic performance always consider IBW for such individuals rather than LBM. - [Weight Loss](https://www.elearning.dlife.in/lds-course-notes/weight-loss-9/) - Notes:---WEIGHT Loss------Intensity- Beginner Proteins - 1.5 g/kg LBM/BW.Fats. - 1.5 g/kg/BCarbs. - 30 g maxIntensity - Intermediate Proteins - 2 g/kg LBM/BW.Fats. - 1.5 g/kg/BWProtein- 30 gramsIntensity - Advance Proteins - 2.5 g/kg LBM/BW.Fats. - 2 g/kg/BWProtein- 30 gramsAbrevations -1. LBM - - [Amylase](https://www.elearning.dlife.in/lds-course-notes/amylase-18/) - Notes: - [Gelatin](https://www.elearning.dlife.in/lds-course-notes/gelatin-15/) - Notes:gelatin is derived from collagen which is the most plentiful in humans and animals a type of protein which is derived from partial hydrolysis of collagen gelatin is found in animal parts that provide us with important amino acids the building blocks of proteinsome people are worried that unsafe manufacturing practices might lead to contamination of gelatin - [Diet And Supplement Planning Goals](https://www.elearning.dlife.in/lds-course-notes/diet-and-supplement-planning-goals-11/) - Notes:Notes:B complex Vitamins - These are groups of 8 water -soluble vitamins performing many key functions in metabolism and energy usage. Vitamin B 12 is essential for peak Athletic performance.B 12 along with folic acid is required in the synthesis of deoxyribonucleic acid ( DNA ) and cell division. I also regulates homocysteine levels. Required - [Flaxseed Oil](https://www.elearning.dlife.in/lds-course-notes/flaxseed-oil-14/) - Notes:flaxseed oil contains plants based omega 3 and alpha linolenic acidother foods especially walnuts and oils[canola and soybean]if you are vegetarian who cannot take fish oil or fish then flaxseed oil may be good solution to help supplement your diet with omega 3 fatty acid - [Egg Shell Membrane](https://www.elearning.dlife.in/lds-course-notes/egg-shell-membrane-19/) - Notes:egg shell consist mostly of calcium carbonate a common form of calciumthe rest is made up of protein and other mineral - [The Randle Cycle: Understanding the Glucose-Fatty Acid Cycle](https://www.elearning.dlife.in/lds-course-notes/the-randle-cycle-understanding-the-glucose-fatty-acid-cycle-6/) - Notes:The randle cycle also known as glucose fatty acid cycle describes the reciprocal regulation of carbs and fatty acids oxidation in muscle and other tissues.This type of cycle should not be mistaken as metabolic cycle.In a metabolic cycle an overall chemical change is brought about by a cyclic chemical reactions , whereas the glucose-fatty acid - [Three States Of Ketosis](https://www.elearning.dlife.in/lds-course-notes/three-states-of-ketosis-14/) - Notes:Ketogenesis is a metabolic pathway that produces ketone bodies, which can provide an alternative form of energy for the body. The body is constantly producing small amounts of ketones bodies that can make 22 ATP each in normal circumstances and it is regulated mainly by insulin. In a state of ketosis , ketone body production - [Aerobic Energy System](https://www.elearning.dlife.in/lds-course-notes/aerobic-energy-system-16/) - Notes:Nutrients follow a complex pathway from ingestion through anabolism and catabolism to energy production .What is Aerobic Energy System ?In the presence of oxygen, the aerobic energy system produces a large number of ATP. This energy system is used in day to day activities and also low - moderate intensity exercises, walking, jogging, cycling, endurance - [Cinnamon](https://www.elearning.dlife.in/lds-course-notes/cinnamon-15/) - Intro.1. Cinnamon. Known for remote antiquity. 2. Adults should avoid eating more than 1 teaspoon of Cassia cinnamon per day, children even less.Benefits.3. Loaded with powerful Antioxidants eg. polyphenols.4. Anti-infla eff, help lower risk of disease5. May improve key risk factors for heart disease incl chole, TriG, BP.6. Significantly incr sensitivity to insulin.7. Shown to reduce - [β-Alanine](https://www.elearning.dlife.in/lds-course-notes/β-alanine-16/) - Intro.1. B-Alanine or Beta-Alanine. Naturally occuring Beta-AA, mod version of AA Alanine, non-essential AA.2. Building block of Carnosine, a mol that helps buffer acid in musc, incr performance in the 60-240 second range. Shown to enhance musc endurance.3. Improve mod to high intensity CV exercise performance, can aid lean mass gain. Carnosine appears to be - [Human Digestive System](https://www.elearning.dlife.in/lds-course-notes/human-digestive-system-80/) - small intestine: Duodenum, Jejunum, Ileumlarge intestine: appendix, caecum, colon, rectumThe broken-down food is absorbed into the bloodstream from SI and nutrients are carried to each cellProteins---break into amino acidsFats---break into fatty acids and glycerolCarbs---break into simple sugarsLI absorbs water and waste food becomes stoolNerves and harmones help control the digestive process - [How Humans Evolved](https://www.elearning.dlife.in/lds-course-notes/how-humans-evolved-53/) - Human trait evoultion: 6 milAdvanced traits: 100kBipedalism: 4 milAust: 60K, Americas: 30kAfrica and Asia: 1.8 to 2 mil - [History of Agriculture](https://www.elearning.dlife.in/lds-course-notes/history-of-agriculture-55/) - humans evolved: 2.6 milcrops: 10kwheat: 8000 BCWheat production : 65 mil tons in 2010Maize: 844 milRice: mil - [Krebs Cycle](https://www.elearning.dlife.in/lds-course-notes/krebs-cycle-16/) - Notes:The Krebs cycle was discovered by Sir Hans Krebs . He was awarded the Nobel Prize in 1953 for this discovery. It is also called the citric acidity cycle and the tricarboxylic cycle ( TCA cycle). Krebs cycle is a part of cellular respiration.it is a series of chemical reactions used by all aerobic organisms - [Curcumin / Turmeric](https://www.elearning.dlife.in/lds-course-notes/curcumin-turmeric-17/) - Notes:TURMERIC IS RECOGNIZED FOR ITS ANTI INFLLAMATORY PROPERTIESBENEFITS-REDUCED INFLAMMATIONIMPROVED ANTIOXIDANT STATUSIMPROVED BLOOD VESSEL FUNCTIONREDUCED HEART ATTACT RISKSIDE EFFECTS- IF TAKEN AT HIGHER DOSESDIGESTIVE ISSUESHEADACHE AND NAUSEASKIN RASHGALLBLADER PROBLEMS - [Ashwagandha](https://www.elearning.dlife.in/lds-course-notes/ashwagandha-19/) - Notes:ASHWAGANDA[ WITHANIA SOMNIFERA] IS A HERB USED IN AYURVEDA ASHWAGANDA IS A PROMINENT HERB IN INDIAN AYURVEDIC MEDICINE AND HAS ALSO BECOME A POPULAR SUPPLEMENT DUE TO ITS HEALTH BENEFITSSTRESS AND ANXIETYDEPRESSIONBOOST TESTOSTERONE AND INCREASED FERTILITY IN MENINCREASED MUCLE MASS AND STRENGHTINFLAMMATION REDUCEDIMPROVE BRAIN FUCTION AND INCLUDING MEMORYCAN REDUCE CORTISOL LEVELSMIGHT HAVE ANTI-CANCER PROPERTIESCAN REDUCE BLOOD - [Ketogenic Diet](https://www.elearning.dlife.in/lds-course-notes/ketogenic-diet-18/) - CLASSIC KETO - F -90%, P - 6%, C -4%MODIFIED KETO - F -82%, P - 12%, C - 6%MCT KETO - F - 73%, P-10%, C - 17%MODIFIED ATKINS KETO - F - 65%, P - 30%, C - 5%LOW GLYCEMIC INDEX KETO - F - 50%, P - 30%, C - 10%INTEMITTENT FASTING - [Lactic Acid Energy System](https://www.elearning.dlife.in/lds-course-notes/lactic-acid-energy-system-13/) - Notes:What is Glycolysis ?Glycolysis is the process of breaking down glucose . Glucose ( glycogen) and breaking down (lysis) . The current energy system delves into anaerobic glycolysis - a 10 step process.Ten steps of glycolysis:-The process of glycolysis occurs in the cytoplasm . A molecule of glucose ( one six -carbon molecule) is oxidised - [ATP-PC Energy System](https://www.elearning.dlife.in/lds-course-notes/atp-pc-energy-system-14/) - Notes:ATP -PC energy System comprises of two steps:1.At rest ATP is hydrolysed to ADP and the phosphate is transferred to creatine to make phosphocreatine.. This occurs in the mitochondria, where ATP levels are high.2. During exercise, phosphocreatine is hydrolysed and phosphate is released to make ATP from ADP. This occurs in the muscles, where ADP - [Somatostatin](https://www.elearning.dlife.in/lds-course-notes/somatostatin-22/) - Notes:Somatostatin inhibits growth hormone from pituitary - [Diabetes](https://www.elearning.dlife.in/lds-course-notes/diabetes-11/) - Notes:Somatostatin regulates release of Insulin & Glucagon.Amylin causes satiety, slows release of stomach contents. - [Obesity Inflammation & Comorbidities](https://www.elearning.dlife.in/lds-course-notes/obesity-inflammation-comorbidities-9/) - Notes:The ability of chronic inflammation to damage the mitochondria lowers the body’s overall ability to function and heal from any infections, and at the same time, it steals energy for about every process going on in the body.Chronic inflammation can be incredibly harmful to your body. Symptoms of chronic inflammation can vary from person to - [Kidney Function Test (KFT)](https://www.elearning.dlife.in/lds-course-notes/kidney-function-test-kft-7/) - Notes: - [β-Alanine](https://www.elearning.dlife.in/lds-course-notes/β-alanine-18/) - Notes:BETA ALANINE IS A MODIFIED VERSION OF THE AMINO ACIDS AND IS A NON-ESSENTIAL AMINO ACIDSBETA ALANINE IS TAKEN AND IS EFFECTIVE FOR HIGH INTENSITY WORK - [Adenosine Triphosphate – ATP](https://www.elearning.dlife.in/lds-course-notes/adenosine-triphosphate-atp-16/) - Notes:Adenosine Triphosphate ( ATP) is a nucleotide consisting of an adenine base attached to ribose sugar, which is attached to three phosphate groups. These three phosphate groups are linked to one another by two high energy bonds called phosphoanhydride bonds.How ATP produces energy :-The key to energy production lies with phosphate groups. Breaking the phosphate - [Secretin](https://www.elearning.dlife.in/lds-course-notes/secretin-12/) - Notes:secretin-neutraizes stomach acid in duodenum by stimulating sodium bicarb rich fluid by pancreas - [Cholesterol & Its Functions](https://www.elearning.dlife.in/lds-course-notes/cholesterol-its-functions-14/) - Notes: CholesterolCholesterol is essential for all animal life, with each cell capable of synthesizing it by way of a complex 37-step process.Most ingested cholesterol is esterified, which causes it to be poorly absorbed by the gut. As a result of this, dietary cholesterol seven to ten hours after ingestion, has little, if any effect on - [Progesterone](https://www.elearning.dlife.in/lds-course-notes/progesterone-19/) - Notes:pregnancy hormone--progehigh progesterone..adrenal hyperplasialow proge..high oestrogen - [L Theanine](https://www.elearning.dlife.in/lds-course-notes/l-theanine-17/) - Notes: - [L Proline](https://www.elearning.dlife.in/lds-course-notes/l-proline-16/) - Proline-a non-essential amino acid-found mostly in cartilage and important for youthful skin, repair muscle, connective tissue and skin damage. Its an important component of collagen for the proper functioning of joints and tendons.-Strengthens heart muscles.-also essential for the immune system.- People with burn injuries and competitive athletes require a higher intake of this supplement. - [L Lysine](https://www.elearning.dlife.in/lds-course-notes/l-lysine-17/) - Notes: - [L Leucine](https://www.elearning.dlife.in/lds-course-notes/l-leucine-18/) - Leucine -- vital amino acid for protein synthesis, regulating blood sugar, promote growth, recovery of muscle and bone tissues and production of growth hormone.- Primary metabolic end product of leucine metabolism is acetyl-CoA and Acetoacetate.-most important ketogenic amino acid.-IsoLeucine is an Isomer of Leucine and also an essential amino acid.-IsoLeucine is involved in growth and - [Energy Pathways](https://www.elearning.dlife.in/lds-course-notes/energy-pathways-18/) - Notes:Energy pathways- Energy is the capacity or power to do work.Human body requires continuous source of energy for any physical activity activity alongside various systems like digestive, respiratory, circulatory, excretory and control system, growth and repair etc. Humans need energy to grow and reproduce and the overallsustainibility of life.All functions of the life process require - [Norepinephrine](https://www.elearning.dlife.in/lds-course-notes/norepinephrine-19/) - HTN medicines and antidepressants interact with norepinephrine - [Berberine](https://www.elearning.dlife.in/lds-course-notes/berberine-18/) - Notes:BERBERINE IS USUALLY FOUND IN THE ROOTS RHIZOMES STEMS AND BARKBERBERINE HAS BEEN SHOWN TO LOWER BLOOD SUAGR LEVELSCAN ALSO CAUSE WEIGHT LOSS AND IMPROVE HEART HEALTHIT IS ONE OF THE FEW SUPPLEMENTS SHOWN TO BE EFFECTIVE AS A PHARMACUETICAL DRUGONE OF THE MAIN ACTIONS OF BERBERINE IS TO ACTIVATE AN EZYME INSIDE CELLS CALLED - [Strategies for Self-Promotion](https://www.elearning.dlife.in/lds-course-notes/strategies-for-self-promotion-5/) - 🌱 Core PhilosophyClient success is the best advertisement—focus on outcomes, not income.Build long-term trust through hand-holding, empathy, and teamwork.Word-of-mouth referrals grow from results, not marketing gimmicks.🖥️ Website StrategiesA professionally designed website is essential—avoid cheap templates.Key website elements:Domain + good hostingWordPress setup with quality themes (e.g., TemplateMonster)Original branding: logo, profile pic, service scope, contact formPublish case - [Three States Of Ketosis](https://www.elearning.dlife.in/lds-course-notes/three-states-of-ketosis-13/) - Notes: Ketosis:Ketogenesis produces 3 types of ketone bodies by breaking down fatty acids.Acetone – excreted in breath and urineAcetoacetate – excreted in urinebeta-hydroxybutyrate – Present in bloodAcetoacetate and beta-hydroxybutyrate are the two ketone bodies used by the body for energy.The body is constantly producing small amounts of ketone bodies that can make 22 ATP each - [Reading Nutrition Labels](https://www.elearning.dlife.in/lds-course-notes/reading-nutrition-labels-6/) - 🏷️ Why Nutrition Labels MatterIn the low-carb world, misleading packaging is common—real food is transparent, but processed foods hide problematic ingredients.Reading just the macronutrients (carbs, fats, proteins) is not enough—the real clues lie in the ingredient list.⚠️ Hidden Ingredients to Watch ForRefined oils (soybean, sunflower) often sneak into nut butters and salad dressings—even when labeled - [Coaching Skills](https://www.elearning.dlife.in/lds-course-notes/coaching-skills-4/) - Here’s a structured summary of the “Coaching Skills” section from the dLife Low Carb Nutrition Diploma course:🧠 Coaching PhilosophyCoaching is a two-way street: good coaches are also coached.It's not about giving solutions, but guiding clients with thoughtful questions to raise awareness.Building a personal rapport is essential—clients should never feel like just a file number.💬 Managing - [Practical Challenges](https://www.elearning.dlife.in/lds-course-notes/practical-challenges-8/) - 🧩 Core ChallengeGetting people to adopt a carbohydrate-restricted diet (like LCHF or Keto) is difficult unless driven by serious health concerns.Cultural norms, addictive carb-based foods, and misinformation contribute to resistance.🍛 Major Obstacles to AdoptionCarb Addiction & Cultural Habits: Sugar, wheat, and seed oils dominate Indian diets; giving up roti and rice feels impossible.Low Animal Protein - [Melatonin](https://www.elearning.dlife.in/lds-course-notes/melatonin-22/) - Notes: melatonin pineal gland..sleep wake cycle From tryptophan at night by pineal glandNight..less night..optic nerve..pineal gland Vit E.. lipophilic antioxidantLight is an imp regulator of sleep - [Managing LCHF While Travelling](https://www.elearning.dlife.in/lds-course-notes/managing-lchf-while-travelling-5/) - 🧳 Key Strategies for LCHF Travel SuccessPreparation Is Vital: Carry low-carb essentials from home to avoid dietary slips—especially during short or long trips.Portable Foods:Nuts (almonds, macadamia, walnuts, etc.), seeds, cheese cubes, boiled eggs, hung curd, dark chocolate, paneerReady-to-use sachets: whey protein, MCT powder, collagen, gelatin, saltBeverages: keto coffee, coconut milk (tetrapak), black coffee, green teaTravel - [Inflammation](https://www.elearning.dlife.in/lds-course-notes/inflammation-20/) - Notes:Inflammation is complex fabric of signals and cellular responses from our immune system that enables our bodies to recognise and respond to infection and injury. Having too weak of an inflammatory response leaves us prone to infection or impaired healing.But having too great of a response or one that remains over active for too long - [Diet & Supplements Goal For MetX Syndrome](https://www.elearning.dlife.in/lds-course-notes/diet-supplements-goal-for-metx-syndrome-6/) - 🍽️ Core Dietary FrameworkDiet Focus: LCHF (Low Carb High Fat) or Ketogenic diets—not low-fat or vegan.Target Conditions: Diabetes, Obesity, PCOS, NAFLD—centered around insulin resistance.Primary Goal: Reduce fasting insulin to ~6–7 µIU/mL.📊 Per Meal Carb ToleranceMax 30g carbs per meal, assuming 3 meals/day and no snacks.Use a transition plan to find individual carb tolerance.Adjust based on ## Site Builder - [Elementor #25188](https://www.elearning.dlife.in/astra-advanced-hook/elementor-25188/) ## Course review - [What you eat and how you move your body is medecine!](https://www.elearning.dlife.in/wdm_course_review/what-you-eat-and-how-you-move-your-body-is-medecine/) - I absolutely loved this course! I was in healthcare all my life so this course helped me to review all of the biochemistry and biology that I had missed so very much. On top of that, there were so many speakers (PhD, MD,ND etc) with the newest research and findings to learn from. I find - [perfectly structured course](https://www.elearning.dlife.in/wdm_course_review/perfectly-structured-course/) - i expected to enter the course with a little knowledge about how to eat and what to eat. this course completely changed my views on that. i realised that there is so much misinformation spread about eating correctly. this course really helped me a lot - [From Caveman to Complexity: Understanding the Biology of Being Human](https://www.elearning.dlife.in/wdm_course_review/from-caveman-to-complexity-understanding-the-biology-of-being-human/) - The LCHF diploma has been a very in-depth unique experience. From the time humans life began to the present moment has been covered exquisitely. Every angle of human existence to consumption /supplements/ the biology, chemistry, and physics have all been reviewed in the course with great integrity. Being able to have great insights of human - [Learning Beyond the Basics](https://www.elearning.dlife.in/wdm_course_review/learning-beyond-the-basics/) - I really enjoyed the course and found it extremely informative and enriching. The scienc-backed content and depth of knowledge have helped me understand nutrition from a much stronger perspective.I’m truly grateful to Mr. Anup Singh for bringing this knowledge to us and to Mr. Narsimha for always being approachable and supportive. The forums, case studies, - [Transformational course on low carb nutrition in this modern era of lifestyle diseases](https://www.elearning.dlife.in/wdm_course_review/transformational-course-on-low-carb-nutrition-in-this-modern-era-of-lifestyle-diseases/) - understanding the information , content and approach of the course to an individual who does not belong to medical fraternity is well maintained. I can tell that any one who is looking for a self paced low carb nutrition course would definitely do this course . The content in this is exceptional and evidence based - [Transformative, Evidence-Based, and Indispensable](https://www.elearning.dlife.in/wdm_course_review/transformative-evidence-based-and-indispensable/) - Completing the dLife Low-Carb Nutrition Course is one of my best health decisions. Every lesson is deeply rooted in solid, science-backed data, clearing up confusion around insulin resistance. The top-class videos, podcasts, and reading materials make complex concepts clear and practical. Mentorship from the team is exceptional, while calculated LCHF recipes make sustaining the lifestyle - [The Most Comprehensive And Value For Investment course](https://www.elearning.dlife.in/wdm_course_review/the-most-comprehensive-and-value-for-investment-course/) - The reason I state what I state is that this course is the most detailed, elaborate and comprehensive diet course. It rightfully backs its claims with science and is not just another propaganda course. it is fantastic as it teaches from scratch and gives a complete picture of everything. It has so many successful reversals - [Truly A Game Changer!](https://www.elearning.dlife.in/wdm_course_review/truly-a-game-changer/) - Wow, what an incredible and rigorous program! The depth of research and the way it connects the science of metabolic health to practical, low-carb living was incredibly valuable. It takes time, effort, and commitment, but every hour of studying was worth it! I’m walking away with the confidence to simplify this complex science into practical, - [Evidence based metabolic health course](https://www.elearning.dlife.in/wdm_course_review/evidence-based-metabolic-health-course/) - An excellent, evidence-based, practical, and in-depth course for professionals who want to understand metabolic health and apply their knowledge to real-world cases, as well as for individuals seeking answers to their own metabolic health concerns. The course places strong emphasis on the science behind metabolic health issues and combines engaging videos, podcasts, and insightful case - [Scientific, Practical and Insightful Course](https://www.elearning.dlife.in/wdm_course_review/scientific-practical-and-insightful-course/) - An excellent, well-structured course with a strong scientific and practical approach . It helped me understand metabolic health, nutrition, and lifestyle concepts much more clearly. Very informative and valuable for practical patient counselling. - ["Evidence-based metabolic care" " Results that speak for themselves".](https://www.elearning.dlife.in/wdm_course_review/evidence-based-metabolic-care-results-that-speak-for-themselves/) - This course is highly recommended for individuals seeking support with metabolic health, and also for professionals who wish to pursue a career dedicated to helping people improve their health and quality of life. Excellent support for reversing metabolic issues. This platform has real data to prove disease reversal is possible. Diet truly changes body and - [Excellent starting point for beginners](https://www.elearning.dlife.in/wdm_course_review/excellent-starting-point-for-beginners/) - The course provides a great path for beginners to learn about nutrition and metabolic health. The curriculum went beyond my expectations, covering everything from basics to real life practical applications. Understanding insulin resistance and its extensive impact was truly an eye-opening experience for me. I found the suggested reading materials and videos especially very helpful. - [Great learning experience, very interactive.](https://www.elearning.dlife.in/wdm_course_review/great-learning-experience-very-interactive/) - - I liked how in depth the course content was. - It really changed the way that I think about metabolic health and nutrition - engaging course - great and helpful instructors. - [A comprehensive life-changing course that can transform the current chronic disease crisis!](https://www.elearning.dlife.in/wdm_course_review/a-comprehensive-life-changing-course-that-can-transform-the-current-chronic-disease-crisis/) - The course covers wide-ranging topics on health and how diet affects it. It breaks-down complex topics in a structured way, which made it easier to understand. There is a good balance between theory & application which gave me the confidence to implement the learnings in real-life. It is completely scientific and evidence-based. It clearly stands - [It teaches you the "why"s and "how"s!](https://www.elearning.dlife.in/wdm_course_review/it-teaches-you-whys-and-hows/) - I knew LCHF works by trying LC over 10 years ago and looking around others doing LCHF in at least weight loss, but I had no idea how and why it works for metabolic health. I also was not sure if LCHF is good. And this course taught me exactly that - the "why" and - [Rational approaches to metabolic disorders are available which are feasible](https://www.elearning.dlife.in/wdm_course_review/rational-approaches-to-metabolic-disorders-are-available-which-are-feasible/) - The need for low carbohydrate intalke has been adequately stressed. The myths regarding consumption of whole grain bread and other carbohydrate diets are cleared. Free radical release due to consumption of refined oils has been stressed. - [Life-changing metabolic education!](https://www.elearning.dlife.in/wdm_course_review/life-changing-metabolic-education/) - 10/10! The dLife Healthcare team has built a perfect bridge between complex science and daily Indian meal planning. I feel empowered to take control of my health and help my community do the same. - [A Much-Needed Course for Modern Lifestyles](https://www.elearning.dlife.in/wdm_course_review/a-much-needed-course-for-modern-lifestyles/) - The Diploma in Low Carb Nutrition & Metabolic Health feels incredibly relevant in today’s world, where lifestyle-related health issues are on the rise. What makes this course stand out is its ability to simplify the science behind food and metabolism. It helped me move beyond common beliefs around “healthy eating” and truly understand what works - [A Much-Needed Shift from Treatment to Prevention in Chronic Disease Management](https://www.elearning.dlife.in/wdm_course_review/a-much-needed-shift-from-treatment-to-prevention-in-chronic-disease-management/) - Dlife low carb nutrition diploma is truly pathbreaking for the Indian vegetarian lifestyle, making metabolic health and diabetes prevention practical for our food habits and family structures. Conventional MBBS/MD training barely covers nutrition, so clinicians would greatly benefit from this perspective. I have personally seen meaningful improvements for myself and my family by following these - [This Health and Science Course completely exceeded my expectations](https://www.elearning.dlife.in/wdm_course_review/this-health-and-science-course-completely-exceeded-my-expectations/) - The content breaks down complex topics with such clarity that everything just clicks. The course has a perfect mix of real-world application and scientific depth kept me engaged. Highly recommend to anyone looking to genuinely understand their health, not just scratch the surface. Thank you Anup and Team - [Real-Life Practical Application](https://www.elearning.dlife.in/wdm_course_review/real-life-practical-application/) - I was genuinely impressed with the Diploma course content. It was comprehensive, well structured and packed with valuable detail, making complex concepts easy to understand - especially for someone like me, who has no prior nutritional background. It has provided me with a strong foundation that has built my confidence in moving from theory into - [Fantastic learning experience](https://www.elearning.dlife.in/wdm_course_review/must-do-course/) - I recently completed the Nutrition and Metabolic Health course with DLife Healthcare, and it was an incredibly valuable experience.The course was exceptionally well structured, making complex topics around metabolism, nutrition, and overall health easy to understand and apply in real life. Each module built logically on the previous one, which helped create a clear and - [science meet yum dishes](https://www.elearning.dlife.in/wdm_course_review/science-meet-yum-dishes/) - The course was exceptionally insightful, offering new daily perspectives on human physiology and the pivotal role of nutrition in managing bodily functions. I am grateful to dLife for providing such a comprehensive case study, complemented by multiple expert-led sessions that significantly deepened my understanding of the subject - [Where science meets the plate](https://www.elearning.dlife.in/wdm_course_review/where-science-meets-the-plate/) - I strongly believe that health begins in the kitchen and is served on a plate. Dlilfe has deepened my understanding of nutritional science through evidence-based learning and real-world application. Although I first tried keto nearly six years ago out of curiosity, this platform has given me the knowledge to properly understand and apply keto and - [I NEEDED THIS COURSE TO UNDERSTAND WHAT MY BODY IS UNDERGOING](https://www.elearning.dlife.in/wdm_course_review/i-needed-this-course-to-understand-what-my-body-is-undergoing/) - i am glad to have been introduced to dlife. i was always so confused about my health and body . continuously joining some fad diets which were expensive and not practically possible and they felt forced and unsatisfied. finally i get it logically . the course is too good and i , looking forward to - [Finally Understand What's Happening Inside My Body](https://www.elearning.dlife.in/wdm_course_review/finally-understand-whats-happening-inside-my-body/) - For years I followed health advice blindly without really understanding why. This course changed that. From understanding insulin resistance to interpreting lipid profiles, everything is explained clearly. The sections on PCOS, thyroid, and metabolic disorders opened my eyes to things my own doctors never explained. And unlike Western courses, this one actually works for Indian - [Phenomenal Eye Opener](https://www.elearning.dlife.in/wdm_course_review/phenomenal-eye-opener/) - Its an eye opener course. Covers all aspects of human biology based metabolism and also disses a few core concepts like CICO and why they are wrong. It also covers the bio-chemistry of how the body reacts and interacts with food via hormonal pathways and cell level signaling. This is something that I did not - [Excellence in Metabolic Health Education](https://www.elearning.dlife.in/wdm_course_review/excellence-in-metabolic-health-education/) - The DLife Metabolic Health Course is extremely informative and clinically practical. The curriculum is well-structured, evidence-based, and focused on real-world management of obesity, insulin resistance, type 2 diabetes, and other metabolic disorders. The faculty simplify complex metabolic concepts with clarity and scientific depth. The case-based discussions and lifestyle-oriented approach have significantly strengthened my clinical confidence - [A Transformative, Science‑Backed Course That Redefines Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/a-transformative-science-backed-course-that-redefines-metabolic-health/) - The dLife Nutrition Diploma stands out for its science‑based, low‑carb approach that focuses on real metabolic healing rather than generic diet advice. The curriculum is structured in a way that makes complex concepts easy to understand, even for someone without a formal nutrition background. I especially liked the clarity of explanations, the practical frameworks for - [Science Based Nutrition for Lifelong Health](https://www.elearning.dlife.in/wdm_course_review/science-based-nutrition-for-lifelong-health/) - This metabolic health course was truly eye-opening and practical. It clearly explained how human nutrition has evolved and why we are facing a growing crisis of chronic diseases today. The concept of species-specific eating and the detailed understanding of insulin resistance helped connect many dots that conventional advice often misses. Overall, the course provides not - [Practical, Evidence-Based Metabolic Wellness](https://www.elearning.dlife.in/wdm_course_review/practical-evidence-based-metabolic-wellness/) - The greatest pull of this curriculum is its practicality. Get blood work and other tests done, get a handle on your own condition and progress to fix ones own life first. The diploma does not asks for any endorsement, the massive results achieved ex ante and ex post are the true endorsement itself. It motivates - [Like a bug , humans will learn what to eat through dlife](https://www.elearning.dlife.in/wdm_course_review/like-a-bug-humans-will-learn-what-to-eat-through-dlife/) - I liked every part of the course, how it evolved, why humans are now in crisis of chronic diseases. how fruit is noty helpful at all, how to gain satietyy. how to remain energetic. the course has given all enlightment on how to review blood works and design meals and exercises. insulin resistance has been - [Counter intuitive,but evidence based](https://www.elearning.dlife.in/wdm_course_review/counter-intuitivebut-evidence-based/) - Though being a dentist,got interested in this course,to increase my scope of practice. Concepts gone through were counter intuitive initially. But testimonies provided by various practitioners at the end of most of the topics,convinced me. Actually conventional biochemistry re aligned with actual physiology and pathi physiology and metabolism with lot of evidences. Food politics part - [INFORMATIVE AND SCIENTIFIC BASED COURSE](https://www.elearning.dlife.in/wdm_course_review/informative-and-scientific-based-course/) - This course change my vison towards metabolic health. before this course i think only maintaining of weight is enough for healthy life, but after go through this course i could understand dept about metabolic health and how food will play important role in our body to maintain healthy life. Before joining this course i had - [A Biochemically grounded, Evidence-Based approach to Metabolic health](https://www.elearning.dlife.in/wdm_course_review/a-bichemically-grounded-evidence-based-approach-to-metabolic-health/) - The "Short-term Diploma in Low Carb Nutrition and Metabolic Health" by DLife.in Academy offers a rigorous, biochemically grounded and clinically relevant understanding of LCHF diet and Intermittent Fasting. It covers topics such as insulin physiology, hyperinsulinemia, insulin resistance and the TOFI phenotype, with strong relevance to the Indian context. The course progresses logically from pathophysiology - [An Empowering and Comprehensive Foundation in Low carb Nutrition and Preventive Health](https://www.elearning.dlife.in/wdm_course_review/an-empowering-and-comprehensive-foundation-in-low-carb-nutrition-and-preventive-health/) - I recently completed the D-Life Low Carb Nutrition and Metabolic health diploma course program and found it to be highly informative and well-structured. The course provides in-depth knowledge of nutrition, lifestyle practices, and how to make informed food choices in today’s complex food environment. It has significantly improved my understanding of preventive health and healthy - [nutrition explained in a very effective manner](https://www.elearning.dlife.in/wdm_course_review/nutrition-explained-in-a-very-effective-manner/) - The dLife Courses on Low-Carb Nutrition and Metabolic Health Diploma offer a refreshing and science-driven approach to understanding modern nutrition and lifestyle medicine. Designed for learners who seek practical knowledge as well as academic depth, the program empowers individuals to explore how food choices directly influence metabolic health, energy balance, and long-term wellbeing. The course - [Biological health with Life span](https://www.elearning.dlife.in/wdm_course_review/biological-health-with-life-span/) - The elaborate course material empowers me to understand what is health and not. Though I tried to empower me in other ways, I could not. After this course completed I could understand and empowered. I advise to those who are interested in health and nutrition to join this dLife course which only available in India. - [Excellent new learning](https://www.elearning.dlife.in/wdm_course_review/excellent-new-learning/) - I got a new learning that root cause of all life style, autoimmune disease, malignancy, systemic disease are excess carbohydrate and Insulin resistance which is going to help me life long. Everything is explained very well with all evidences. This was not taught in medical college in spite of studying in one of the best - [An Insightful Course that truly enhanced my understanding of health and well-being](https://www.elearning.dlife.in/wdm_course_review/an-insightful-course-that-truly-enhanced-my-understanding-of-health-and-well-being/) - Being the youngest ever to do this course I felt so grateful to be doing it. dLife's LCHF diploma course has changed my perspective towards food and health. The course is so perfectly curated, with each topic being so informative. It made me unlearn all the myths and false information about food. I would recommend - [Venkateswarlu Koya](https://www.elearning.dlife.in/wdm_course_review/venkateswarlu-koya/) - Before this LCN and MH Diploma,though I used to listen videos of stallwarts of International Metabolic Health Practitioners, I am not capable to understand them. After this course I empowered.Course well structured comprehensively step by step formulated.This course made the non medicals to enter medical stream. It is peak when reached Forums to deal with - [Empowers all with metabolic dysfunction](https://www.elearning.dlife.in/wdm_course_review/empowers-all-with-metabolic-dysfunction/) - The course has empowered me with the neccessary information, tools and insights, to deal with the everday frustration that Type 2 Diabetes keeps bringing up. I am now aware of how various organs in the body respond to elevated blood sugar. And how it is not sugar but Hyperinsulinemia that is at the centre of - [The Trust Worth Ness of dLife that resonates with Walk the Walk and the Talk the Talk](https://www.elearning.dlife.in/wdm_course_review/the-trust-worth-ness-of-dlife-that-resonates-with-walk-the-walk-and-the-talk-the-talk/) - Talking about the truth in the mainstream, which boomerangs in other cultures, that attract adverse criticism against the dLife. Of course, people are people. They have every right to take it right or wrong. But facts are facts, and they never change against the contradictory opinions of others. Fighting for a noble cause deserves courage - [Transformative and Scientifically Solid !!](https://www.elearning.dlife.in/wdm_course_review/transformative-and-scientifically-solid/) - I found the LCHF DLife Course exceptionally well- structured, evidence - based and practical. It simplifies complex metabolic concepts into clear, steps that can be implemented in clinical practice and daily life. What truly stands out is the strong scientific foundation combined with practical application. The course empowers health professionals and other individuals to understand - [Thorough and data driven!](https://www.elearning.dlife.in/wdm_course_review/thorough-and-data-driven/) - I leave this course equipped to guide people who want to improve their metabolic health. I can read and interpret data around blood tests and critical health markers. I can use this knowledge to guide dietary interventions, offer guidance on supplements, and to track progress as they pursue wellness. I can design appropriate dietary guidance - [A Science-Backed Course That Changes How You Understand the Human Body](https://www.elearning.dlife.in/wdm_course_review/a-science-backed-course-that-changes-how-you-understand-the-human-body/) - The dLife Certification Course exceeded my expectations in every way. It provided a clear, science-based understanding of how the human body works, especially in relation to metabolism, hormones, nutrition, and lifestyle. What I liked most is that the course focuses on why things happen in the body, not just what to do. Before this course, - [Excellent, practical course on metabolic health and disease reversal. Clear concepts, strong scientific approach.](https://www.elearning.dlife.in/wdm_course_review/excellent-practical-course-on-metabolic-health-and-disease-reversal-clear-concepts-strong-scientific-approach-and-highly-use/) - It will definitely help to gain a strong scientific understanding of metabolic health, learn practical protocols for lifestyle disease reversal, and build confidence in counseling and long-term patient management using evidence-based nutrition and lifestyle approaches. - [A Master Course in Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/a-master-course-in-metabolic-health/) - As a medical doctor, I highly recommend the Dlife LCHF Metabolic Health Diploma. The detailed, evidence-based program demystifies Low-carb High-fat nutrition for managing Diabetes, PCOS & Metabolic syndrome, amongst others. It is tailored perfectly even for Indian diets, with practical meal plans & a huge database of recipes. The course is ideal for Doctors, patients - [The Britannica of Metabolic Health & Nutritional Learning](https://www.elearning.dlife.in/wdm_course_review/the-britannica-of-metabolic-health-nutritional-learning/) - The dLife Low-Carb and Metabolic Health course is an exceptional, research-driven program offering deep, practical knowledge on nutrition, metabolism, and lifestyle disease reversal. Content is comprehensive, authoritative, and easy to apply, making it feel like the Britannica of metabolic health coaching. The coaching framework strengthens understanding by guiding learners on how to translate complex science - [This course is a must for all doctors.](https://www.elearning.dlife.in/wdm_course_review/this-course-is-a-must-for-all-doctors/) - I am delighted and content that I decided to take this course . Taking this course is an important milestone in my career. - [Very Apt and Science-backed course](https://www.elearning.dlife.in/wdm_course_review/very-apt-and-science-backed-course/) - This is an exceptionally comprehensive and well-structured nutrition course. It combines science with real-world lifestyle guidance and essential life skills. What makes it truly unique is the way every concept is explained with proper context and logic, leaving no confusion about healthy choices. The course also sheds light on how the food and pharmaceutical industries - [Well designed course with great attention to detail](https://www.elearning.dlife.in/wdm_course_review/well-designed-course-with-great-attention-to-detail/) - This course has truly exceeded my expectations. I thoroughly enjoyed the interviews with several of my favorite metabolic health experts from around the world, wonderfully hosted by the dLife team The course is very well structured, with proper references and easy navigation through forum links. What impressed me most was the meticulous attention to detail - [The best course on nutrition](https://www.elearning.dlife.in/wdm_course_review/the-best-course-on-nutrition/) - Dlife created the most comprehensive course in this field it is highly recommended. Thanks to Anup Sir for creating Dlife community. - [My Metabolic Health - In My Hands](https://www.elearning.dlife.in/wdm_course_review/my-metabolic-health-in-my-hands/) - he dLife Metabolic Health diploma course provides truly essential health information that is often unfamiliar to the general public and overlooked by many mainstream doctors. The curriculum is exceptionally well-organized and explains the complex topic of metabolic health in a simple possible way. This knowledge is genuinely important. If we can empower more people with - [A Knowledge hub for a healthy Lifestyle](https://www.elearning.dlife.in/wdm_course_review/a-knowledge-hub-for-a-healthy-lifestyle/) - A complete knowledge hub for a healthy lifestyle, offering an in-depth understanding of the mechanisms involved in metabolism, with vital dos & don'ts for maintaining an equilibrium state of health. This neatly curated content provides the necessary principles for progressive life.USP is its continuous learning-enhanced environment. A must-do for one in every family to safeguard - [Unfiltered pure science...](https://www.elearning.dlife.in/wdm_course_review/unfiltered-pure-science/) - This is very informative course covering important pillars of health. The unfiltered science gives insights into reality and illusion and make me knowledgeable to make right food choices. Kudos to Dlife for making this happen. - [WISDOM](https://www.elearning.dlife.in/wdm_course_review/wisdom/) - This course is concise, practical, and highly informative. It explains the science behind low-carb, high-fat nutrition in a clear and easy-to-understand way. The modules are well-structured and guided by knowledgeable instructors. Whether you’re a beginner or already familiar with LCHF, this course provides valuable insights that can be applied both personally and professionally. Highly recommended - [Science and depth of overall healthy life](https://www.elearning.dlife.in/wdm_course_review/science-and-depth-of-overall-healthy-life/) - I'd tried various diet fads in my previous time, and also continued endurance training, and saw no significant/longterm benefits. Came to know about this course through reference, and found it takes scientic approach rather than the popularist one. For all the topics of day to day and for long term health, the basics and the - [Dlife - towards a life changing and enriching journey](https://www.elearning.dlife.in/wdm_course_review/dlife-towards-a-life-changing-and-enriching-journey/) - I loved the thought process of the founder and the team in what went into making of Dlife…… giving fellow humans the gift of health and longevity. Has exceeded all expectations and i feel Dlife is contributing in a big way to social cause and nation building in a way! - [You WILL get better](https://www.elearning.dlife.in/wdm_course_review/you-will-get-better/) - I recently completed a course on low-carb nutrition and metabolic health, and despite years of studying the field, watching hundreds of videos, and following countless experts, I was genuinely surprised to discover a program right here in India that surpasses many Western offerings. The DLife course provides a uniquely Indian, deeply practical, and science-driven approach - [Every module feels purposeful, evidence-based, and directly applicable to real-world scenarios.](https://www.elearning.dlife.in/wdm_course_review/every-module-feels-purposeful-evidence-based-and-directly-applicable-to-real-world-scenarios/) - The Low Carb Nutrition and Metabolic Health Diploma by Dlife.in is one of the most comprehensive and well-structured nutrition courses I’ve come across. The curriculum is exceptionally exhaustive, covering everything from foundational metabolic science to practical low-carb clinical applications. What stands out most is the relevance of the content—every module feels purposeful, evidence-based, and directly - [Exceptionally Well-Curated Course](https://www.elearning.dlife.in/wdm_course_review/exceptionally-well-curated-course/) - The course stands out for its strong scientific foundation. Every concept is backed by current research and clear explanations that make it easy to understand. Overall, it's a thoughtfully curated and scientifically grounded course that benefits both medical and non-medical learners alike. I would love to see this course made mandatory for 12th grade students, - [The only life is D Life way.](https://www.elearning.dlife.in/wdm_course_review/the-only-life-is-life-way/) - Very rich content taught in very interesting way with text and its context, videos and podcasts of stalwarts . A must course who crave for healthy life style. Course also includes sports nutrition. Unlimited LCHF and Keto recipes liste . So what to eat when on LCHF lifestyle is taken care of. Amazing content and - [Low Carb Nutrition Master course](https://www.elearning.dlife.in/wdm_course_review/low-carb-nutrition-master-course/) - This course is the one stop shop for low carb nutrition. Its a beginners 101 to masters degree information and knowledge combined in one course.This is like no other course as this gives us a sustainable lifestyle for Indians. This is the need of the hour so all can change their lives and lives of - [A journey to healthy life](https://www.elearning.dlife.in/wdm_course_review/a-journey-to-healthy-life/) - The course is a NEED of the present times, very knowledgeable and understandable by everybody with quality and vast material. The study material is extremely helpful in understanding the concepts well. I highly recommend this course to whoever is willing to bring a positive change in their lives, especially in today’s world where we are - [With dlife..Master nutrition](https://www.elearning.dlife.in/wdm_course_review/with-dlife-master-nutrition/) - The course is far beyond my expectations. I learnt what I didn't learn during my medical education..in length, depth , in every aspect. Well structured and easy to understand. Flexible learning, self paced and you can switch between mobile and laptop Experts videos included to guide and explain Nutrition data is beyond imagination Quick access - [Comprehensive Low Carb Nutrition Course!](https://www.elearning.dlife.in/wdm_course_review/comprehensive-low-carb-nutrition-course/) - I recently completed this course, and I was very impressed with its depth and quality. The course covers everything about low-carb nutrition in a clear and scientific way. It explains how a low-carb lifestyle can improve overall health, help avoid many modern diseases like diabetes and obesity, and even support longevity. The modules are well-structured, - [Transformative, Informative,Made In India](https://www.elearning.dlife.in/wdm_course_review/transformative-informativemade-in-india/) - The Dlife Nutrition Diploma Course has been a reality check, breaking long-held societal myths about food and health. It offers transformative, science-based knowledge that helps tackle the growing epidemic of metabolic diseases. This course not only redefines how we view nutrition but empowers lasting lifestyle change. Personally, I’ve lost 20 kgs and sustained it—something I - [Life Transforming & Comprehensive Course.](https://www.elearning.dlife.in/wdm_course_review/life-transforming-comprehensive-course/) - Comprehensive, well balanced and carefully composed diploma course covering all aspects of health and modern-day chronic diseases, which are basically resulting from our modern-day diet and lifestyle. Joining the diploma course is the best and most important decision I have taken, and this knowledge will help me immensely in maintaining great health for myself and - [Supreme content -A Life transforming event](https://www.elearning.dlife.in/wdm_course_review/supreme-content-a-life-transforming-event/) - I liked the substance /content of the course,very nicely compiled and yet easy to understand Subject matter seems to be authentic backed by research and real life evidences.And above all this course is good enough for improving oneself life.Infact I feel this is hightime that a content of this kind may be made part of - [A Transformative Journey: Evidence-Based Excellence in Low Carb Nutrition Education](https://www.elearning.dlife.in/wdm_course_review/a-transformative-journey-evidence-based-excellence-in-low-carb-nutrition-education/) - Completing the Low Carb Nutrition & Metabolic Health Diploma has been one of the most rewarding educational experiences of my life. This comprehensive program stands out not just for its depth of content, but for its exceptional integration of scientific rigor, practical application, and community support. The curriculum is masterfully designed, taking learners on a - [Recommendation for a healthy life](https://www.elearning.dlife.in/wdm_course_review/recommendation/) - The course is absolutely necessary for anyone who wishes to learn nutritional values. It has enabled me to at least talk about the extra consumption of carbs that has been normalized to a dangerous extent. Thereby, would highly recommend the respective course to anyone who wants to eradicate that issue of over and bad eating. - [Understanding the metabolic functions of the Human body](https://www.elearning.dlife.in/wdm_course_review/understanding-the-metabolic-functions-of-the-human-body/) - The Dlife diploma on Low carb nutrition and Metabolic Health can be considered a bible for prevention, cure and maintaining optimum health. This course provides the knowledge to take matters into our own hands and reverse health problems. A course that is a must for anyone seeking answers to chronic health conditions. - [From Curiosity to Clarity: My Transformational Experience with DLife Low carb Nutrition & Metabolic Health Diploma”](https://www.elearning.dlife.in/wdm_course_review/from-curiosity-to-clarity-my-transformational-experience-with-dlife-low-carb-nutrition-metabolic-health-diploma/) - Enrolling in the DLife Diploma in Low Carb Nutrition & Metabolic Health has been one of the most rewarding decisions of my life. I joined with curiosity, but what I gained was far beyond knowledge — it was clarity, confidence, and a complete shift in how I view health and nutrition. The course is designed - [A well curated metabolic health course](https://www.elearning.dlife.in/wdm_course_review/a-well-curated-metabolic-health-course/) - It transformed my understanding of food, health, and my perspective on metabolic diseases. It offers hope to those suffering from these conditions by providing in-depth insights into metabolic diseases and guidance on how to reverse them. - [Metabolic health game changer](https://www.elearning.dlife.in/wdm_course_review/metabolic-health-game-changer/) - I liked the detailed scientific explanation of metabolic and autoimmune health conditions in an easy and simple language. My expectations were to clearly understand the root causes for the various metabolic health conditions . - [Structured Learning for Lifestyle Improvement: The Academic Value of the D-Life Diploma](https://www.elearning.dlife.in/wdm_course_review/structured-learning-for-lifestyle-improvement-the-academic-value-of-the-d-life-diploma/) - The D-Life Diploma is one of the most comprehensive and relevant study platforms for anyone truly committed to taking control of their health. It clears long-held misconceptions, offering a clear and practical roadmap to a healthier lifestyle. This program is genuinely transformative and highly recommended for anyone seeking lasting, positive change. - [The d Life LCHF Course is a North Star, guiding everyone on the rightful Path to good health!](https://www.elearning.dlife.in/wdm_course_review/the-d-life-lchf-course-is-a-north-star-guiding-everyone-on-the-rightful-path-to-good-health/) - Highly informative and well researched Course with a new paradigm shift towards managing Chronic Metabolic disorders! This Course is an absolute and delightful treasure of Knowledge meant for everyone who wants to become a healthier version of themselves and guide others to do the same! - [A course like none other - Power packed with science and real-world applications!](https://www.elearning.dlife.in/wdm_course_review/a-course-like-none-other-power-packed-with-science-and-real-world-applications/) - The globally recognised Dlife.in Low Carb & Metabolic Health Diploma felt less like a course and more like a journey to me. It took me from understanding the basics of LCHF and nutrition science to seeing how they truly work in real life to tackle metabolic and other diseases like cancer, autoimmune, etc. The course - [This is a treasure trove](https://www.elearning.dlife.in/wdm_course_review/this-is-a-treasure-trove/) - In other words this is like a oasis in the middle of a desert full of misinformation and captalistic and exploitative modern food industry that is turning out to determental to human health. This is a one stop shop for all the thing one needs to take their health into control and improve it. - [Incredible insight to health](https://www.elearning.dlife.in/wdm_course_review/incredible-insight-to-health/) - dLife’s course on low carb nutrition and metabolic health is an eye changer for me. As someone with metabolic syndrome and insulin resistance, the course, the forum and WhatsApp group gave me so many insights on health from my perspective. The learnings from this course are immense - and it covers a wide range of - [A Valuable Course for Health and Wellness](https://www.elearning.dlife.in/wdm_course_review/a-valuable-course-for-health-and-wellness/) - I recently completed the Low Carb Nutrition Diploma for Metabolic Health. This course was a real eye-opener, expanding my understanding of how nutrition impacts metabolic health. The content was clear, engaging, and easy to follow, making complex concepts much more accessible. It enhanced my knowledge significantly and gave me practical insights that I can apply - [Life-Changing Journey Through dLife.in’s Nutrition Diploma Course](https://www.elearning.dlife.in/wdm_course_review/life-changing-journey-through-dlife-ins-nutrition-diploma-course/) - Enrolling in the dLife.in has been one of the most transformative decisions of my life—both personally and professionally. Before this course, I had only a surface-level understanding of nutrition. From the very first module, I realized this wasn’t just another online course filled with recycled information. The scientific depth, the clarity of explanation, and the - [Introduced me to the world of evidence-based low-carb nutrition and its potential to heal illnesses](https://www.elearning.dlife.in/wdm_course_review/introduced-me-to-the-world-of-evidence-based-low-carb-nutrition-and-its-potential-to-heal-illnesses/) - DLife introduced me to low-carb nutrition and its application in an Indian context. The course dives deep into the biochemistry and metabolic pathways, highlighting the most overlooked cause of metabolic disorders, i.e. "Insulin Resistance". It has given me a new, simple, and effective way of looking at nutrition that I can follow for the rest - [The best cource there is](https://www.elearning.dlife.in/wdm_course_review/the-best-cource-there-is/) - The cource have been brilliant what I like the most is how community has been built where you actually learn and not just skip the video so all the dlife people actually study through the material they know thier stuff nobody can beat them - [Deep Science, Deeper Community: DLife always Delivers](https://www.elearning.dlife.in/wdm_course_review/deep-science-deeper-community-dlife-always-delivers/) - DLife is deep, science-first learning— rigorous, and outcome-driven. Imho course itself is ~30% of the value; the community does the heavy lifting: ~50% from an incredibly rich forum where theory becomes practice, and ~20% from a vibrant WhatsApp group with daily learning nuggets and success stories. Net-net: the content builds the framework and the community - [Empowering Professionals with Science-Based Insights: A Review of the Low Carb Nutrition & Metabolic Health Diploma](https://www.elearning.dlife.in/wdm_course_review/empowering-professionals-with-science-based-insights-a-review-of-the-low-carb-nutrition-metabolic-health-diploma/) - The Low Carb Nutrition & Metabolic Health Diploma is an excellent, evidence-based program that deepens understanding of how low-carb strategies support metabolic health. It blends science with practical application, covering diabetes, obesity, PCOS, and more. The course balances theory, case studies, and coaching tools, while addressing myths and controversies. Flexible and well-structured, it equips professionals - [Most up to date and life changing course](https://www.elearning.dlife.in/wdm_course_review/most-up-to-date-and-life-changing-course/) - Joined the course to take charge of my own and family's health after observing how everyone young and old are suffering from one or the other metabolic issues.Being interested in healthcare since ever,I happened to find this course and there has been no looking back.Studying at my age with an already demanding career and family - [A kick-start to life changing approach of health and nutrition.](https://www.elearning.dlife.in/wdm_course_review/a-kick-start-to-life-changing-approach-of-health-and-nutrition/) - The content in the course is extremely well-structured and highly insightful. The topics in course are explained in such a simple manner, that, to give an example, you can easily connect the dots from insulin resistance to high level of triglycerides in your lipid panel test. What also struck me was it explains the evolution - [A Learning Experience That Truly Stays With You](https://www.elearning.dlife.in/wdm_course_review/a-learning-experience-that-truly-stays-with-you/) - I really loved this course! It takes something as complicated as metabolism and explains it in a way that actually makes sense. Even with my background in health psychology, I found myself learning things I can put into practice right away. The mix of videos, quizzes, and discussions kept it engaging and made sure the - [Understand the most complex control system - The Human Body and its control via Diet](https://www.elearning.dlife.in/wdm_course_review/understand-your-the-most-complex-control-system-the-human-body/) - This course provides clarity and practical understanding of the most complex control system - the human body and how diet affects its functioning. The complex topics such as insulin resistance, fat metabolism, and energy pathways are made easy to understand, even for non-medical people (like me). The forum has real-life case studies and excellent peer - [Quality of content and pedagogy unparalleled](https://www.elearning.dlife.in/wdm_course_review/quality-of-content-and-pedagogy-unparalleled/) - The quality of content and the pedagogy is unparalleled anywhere in the low carb nutrition space. Its a practical guide that not just sticks to the deep technical aspects of low carb/ketogenic diet but also guides one on the practical aspects of consulting that gives win-win outcomes between you and the clients that need the - [Right fuel makes for a smooth journey.](https://www.elearning.dlife.in/wdm_course_review/right-fuel-makes-for-a-smooth-journey/) - For years, I enjoyed watching reels and podcasts on nutrition, taking tips and apply in my daily life. I thought I was doing everything right-until I joined the Dlife course. That’s when I discovered how much misinformation I had unknowingly been following. When I incorporated the learnings from Dlife, the 20:20:60 protocol and the maximum - [Vast compendium of knowledge](https://www.elearning.dlife.in/wdm_course_review/vast-compendium-of-knowledge/) - Extremely comprehensive course dealing with basic human biology and it’s application ,something I had failed to grasp during student days.The lectures are in-depth and made all the more engaging by inclusion of videos from global gurus as well as practical applications by the mentors. Armed with the confidence the course has given me and support - [A Life Changing course](https://www.elearning.dlife.in/wdm_course_review/a-life-changing-course/) - This is one of the best courses I have ever taken. The content is exceptionally well structured, scientifically robust and incredibly relevant. What impressed me most was how practical and applicable it was - not just theories, but real world strategies backed by research and clinical experience. The instructors are outstanding, knowledgeable, passionate and engaging - [The Game-Changer in the Metabolic Health Industry](https://www.elearning.dlife.in/wdm_course_review/the-game-changer-in-the-metabolic-health-industry/) - This course was a complete eye-opener for me and changed my perspective towards overall health and wellbeing. Course content is completely backed by scientific literature and references. So, it was more of an unlearning and happy realization that it is just a beginning to improved metabolic health style! Highly recommended to anyone, who wishes to - [Apex course in understanding and improving metabolic health](https://www.elearning.dlife.in/wdm_course_review/apex-course-in-understanding-and-improving-metabolic-health/) - This course is an impactful journey and would highly recommend to everyone whom I know. The course is equipped with a superlative pedagogy. The curriculum is grounded in science-based research, and fundamental logic. The course provides valuable insights and dispels myths around metabolism and provides clarity about nutrition. It encourages transformational shift towards improving your - [This course is about taking control of your Health](https://www.elearning.dlife.in/wdm_course_review/this-course-is-about-taking-control-of-your-health/) - Highly recommended to anyone who wants to take control of their personal and loved one's health in their own hands, this course has a science backed nutritional approach which teaches you to eat species appropriate diet, breaking myths and believes in the process, empowering you with the knowledge to live a pill/disease free active and - [A well-structured , comprehensive and rich content course on nutrition & metabolic health](https://www.elearning.dlife.in/wdm_course_review/a-well-structured-comprehensive-and-rich-content-course-on-nutrition-metabolic-health/) - dLife low carb nutrition & metabolic health diploma course builds our knowledge to move towards the management in core areas of nutrition, metabolic health diseases, research & evidence based practice. It provides the plethora of knowledge about nutritional science, human biology, physiology & biochemistry. To avoid harmful medicines and expensive lifelong treatments, every individual should - [An Invaluable Course for Anyone Serious About Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/an-invaluable-course-for-anyone-serious-about-metabolic-health/) - This course exceeded expectations by offering a structured, science-backed deep dive into metabolic health. It helped me connect scattered knowledge into a cohesive understanding—covering everything from insulin resistance to lifestyle, exercise, supplementation and nutrition. The forum, mentors, and community foster continuous learning. In a world full of conflicting information, this course stands out as a - [Incredibly eye-opening and empowering Low Carb Metabolic Course.](https://www.elearning.dlife.in/wdm_course_review/incredibly-eye-opening-and-empowering-low-carb-metabolic-course/) - The course provides a deep understanding of how our body processes carbohydrates, insulin resistance, and the science behind metabolic health. It breaks complex topics into simple, actionable insights that anyone can apply in daily life. The lessons were well-structured, evidence-based, and supported by real-life case studies. I especially appreciated how it covered not just the - [A Science-Backed Guide to Reversing Metabolic Damage](https://www.elearning.dlife.in/wdm_course_review/a-science-backed-guide-to-reversing-metabolic-damage/) - After completing the LCHF course from dLife, I can confidently say it’s been a turning point in how I approach food and health. Being someone deeply interested in holistic healing, this course gave me the clarity and direction I was looking for. The best part is that it is science-backed, yet simple. The way complex - [One of the most comprehensive courses on metabolic health and nutrition](https://www.elearning.dlife.in/wdm_course_review/one-of-the-most-comprehensive-courses-on-metabolic-health-and-nutrition/) - A fantastic course that provides indepth information on the details of how the different pathways work inside the body from a biology and chemistry perspective, the different health issues that are caused when these processes are interrupted and how we can fix these health concerns using the right nutrition. Some of the material can seem - [In-depth, 100% science backed and incomparable course](https://www.elearning.dlife.in/wdm_course_review/in-depth-100-science-backed-and-incomparable-course/) - I was absolutely amazed at the depth of the course content. I loved all the references and studies cited in all of the various topics of metabolic health. It gave me the confidence to step in this growing field of metabolic health with continuous support from mentors and seniors. I would recommend this course to - [Exceptional, Peerless Course in Nutrition and Metabolic health](https://www.elearning.dlife.in/wdm_course_review/exceptional-peerless-course-in-nutrition-and-metabolic-health/) - A very thoughtfully designed, unparalleled course content, which changes your perception towards diet, nutrition and health. Course content is supported by robust scientific literature and references. The learning experience is enriched by the videos from the eminent gurus in the nutrition field. The course challenges the conventional dietary dogmas and presents a root cause driven - [Dlife LCHF Nutrition Diploma was super educative and eye opening](https://www.elearning.dlife.in/wdm_course_review/dlife-lchf-nutrition-diploma-was-super-educative-and-eye-opening/) - The course explains complex medical concept in an easy way to understand. I like the structure and categorization of the topics, the virtual interactions, and you tube videos as well. It was a great idea to allow people watch these concepts being explained. I am glad i took this course, because now i know more - [A Treasure Trove of Knowledge – Transformative Learning Experience](https://www.elearning.dlife.in/wdm_course_review/a-treasure-trove-of-knowledge-transformative-learning-experience/) - This course has been an absolute eye-opener for someone like me who once believed I had a decent understanding of human physiology and biochemistry. The content is meticulously curated and structured in a logical, progressive manner that builds your knowledge step by step. The accompanying videos are concise, relevant, and significantly enhance the concepts. Hands - [Eye-opening, Fundamental and Transformative Course](https://www.elearning.dlife.in/wdm_course_review/eye-opening-fundamental-and-transformative-course/) - This course breaks down complex metabolic concepts into something anyone can understand and apply. As someone from a non-medical background, I found it extremely practical and well-structured. The videos, quizzes, and forum all come together to build real clarity. It surely empowered me with a confidence that I can help people cure their metabolic syndromes. - [Reversal of metabolic Diseases](https://www.elearning.dlife.in/wdm_course_review/reversal-of-metabolic-diseases/) - This course is the best course available which helps to reverse metabolic Diseases.It is designed by the most Talented Anup Singh who is an silver medalist IITian from Roorkee.I recommend this course to everyone and also for Doctors.Thank you Anup for creating such a wonderful course - [Evidence based LCHF Nutrition for Metabolic Health Mastery](https://www.elearning.dlife.in/wdm_course_review/evidence-based-lchf-nutrition-for-metabolic-health-mastery/) - I loved the course’s practical, science-backed approach, with 800+ references and 60+ videos. The forum is an invaluable resource for a practical approach to metabolic health. As I progressed through the course , the expectations I had were exceeded by what I got from this course. - [Practical, In depth & lot of learning](https://www.elearning.dlife.in/wdm_course_review/practical-in-depth-lot-of-learning/) - evidence based with clinical application in simple language. anyone and everyone should be aware of their meal, as food is the medicine. worth your time and regular updates, lot of diet recipes, overall well structured course - [Now my plan is to apply all the content I learnt here on myself! That will take the education further!](https://www.elearning.dlife.in/wdm_course_review/now-my-plan-is-to-apply-all-the-content-i-learnt-here-on-myself-that-will-take-the-education-further/) - There are plenty of other reviews that talk about the quality of the course material and I couldn't agree more. Through various video links in the course and through dlife's metabolic health conference, I am now exposed to stalwarts in the field of nutrition. When living in the USA, I was part of the community - [Evidence based approach to metabolic health](https://www.elearning.dlife.in/wdm_course_review/evidence-based-approach-to-metablic-health/) - The course is comprehensive in the range of topics it covers—from foundational health concepts to metabolic and lifestyle insights. It’s not just surface-level content; each topic includes references to scientific literature and experts that invite deeper exploration. Some feedback: the quizzes could be improved. Nutrition is one of those things that 5 experts will give - [Most comprehensive course](https://www.elearning.dlife.in/wdm_course_review/most-comprehensive-course/) - The D Life Diploma course is comprehensive, well structured, very meticulously Drafted,course on metabolic health. It covers all aspect related to metabolic health such as,Nutrition, various metabolic Diseases,backed by Research. I am greatful to Anup sir & team for the knowledge I gained through this course. I recommend this course to those who want to - [The complete course](https://www.elearning.dlife.in/wdm_course_review/the-complete-course/) - The D-Life Metabolic Health Diploma is a comprehensive course that systematically explores low-carbohydrate and ketogenic nutrition through the lens of evolutionary biology, endocrinology, and metabolic science. The curriculum spans critical topics such as insulin resistance, hormonal interplay, and the therapeutic application of LCHF and ketogenic diets in conditions like type 2 diabetes, obesity, PCOS, etc. - [Unique course on Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/unique-course-on-metabolic-health/) - The D Life course is one of It's kind in the Health and Nutrition sector. It very well explains the bodies functions and scientifically shows the connections of each of them with each other. It shows us how nutrition plays a significant role in our living and how to get a hold of it to - [Master Metabolic Health the LCHF Way](https://www.elearning.dlife.in/wdm_course_review/master-metabolic-health-the-lchf-way/) - It’s a well-structured, research-backed program that dives deep into nutrition, metabolic health, and lifestyle change. From insulin resistance to diabetes reversal, everything is explained clearly with real-world Indian context. It truly changes the way you look at food and health. Highly recommended for anyone serious about root-cause healing and sustainable wellness. Hats off to the - [A holistic approach—connecting nutritional science with metabolic health.](https://www.elearning.dlife.in/wdm_course_review/a-holistic-approach-connecting-nutritional-science-with-metabolic-health/) - This 24-week Low Carb Nutrition & Metabolic Health Diploma exceeded my expectations in both depth and breadth. As someone who regularly tests food's impact on glucose levels, I found the scientific foundation exceptional. The course strikes an impressive balance between theoretical knowledge and practical application. What sets it apart is its holistic approach—connecting nutritional science - [Health, fitness and longevity, all in one course.](https://www.elearning.dlife.in/wdm_course_review/health-fitness-and-longevity-all-in-one-course/) - I joined this course to gain a deep understanding of low-carb nutrition and metabolic health, and I've had a really positive experience. The study materials are comprehensive, including research papers, podcasts, and additional resources in the further reading sections, which I find very helpful. The biggest advantage of this course is its practical approach. The - [Recommended Course for all Doctors](https://www.elearning.dlife.in/wdm_course_review/recommended-course-for-all-doctors/) - Course Review I recently completed the LCHF course offered by Dlife India, and I can confidently say it has been a transformative experience. This course is meticulously designed to educate participants about the Low-Carb High-Fat (LCHF) lifestyle, making it accessible for everyone, regardless of their prior knowledge. From the outset, the course was well-structured and - [Comprehensive and well-structured course](https://www.elearning.dlife.in/wdm_course_review/comprehensive-and-well-structured-course/) - The dLife diploma course is a carefully designed and highly detailed program that provides a structured framework for understanding the fundamentals of metabolic health. Built on the principles of real food nutrition, it goes beyond the basics, offering valuable insights into how a low-carb lifestyle can enhance nutrition, energy levels, and overall well-being. Additionally, the - [Excellent course to understand LCHF nutrition](https://www.elearning.dlife.in/wdm_course_review/excellent-course-to-understand-lchf-nutrition/) - I recently completed the LCHF Nutrition course with Dlife.in, and it’s been a solid learning experience. What really stood out to me was how practical the content is. I joined the course to better understand how food affects metabolism, especially things like blood sugar and insulin, and I wasn’t disappointed. The modules are clear, structured, - [The learning experience was enriching, and I’m grateful for the knowledge gained.](https://www.elearning.dlife.in/wdm_course_review/the-learning-experience-was-enriching-and-im-grateful-for-the-knowledge-gained/) - I recently completed the nutrition course and found it to be highly insightful and well-structured. The content was comprehensive, covering all major topics in depth, with a strong emphasis on evidence-based knowledge. The course design was intuitive and learner-friendly, making complex subjects easy to grasp even for beginners. I genuinely appreciate the effort and expertise - [A Life-Changing Journey with dLife's Low Carb Nutrition Diploma](https://www.elearning.dlife.in/wdm_course_review/a-life-changing-journey-with-dlifes-low-carb-nutrition-diploma/) - The dLife Low Carb Nutrition Diploma is life-changing. Scientifically designed like a crash MBBS course, it helped me understand my body, improve metabolic health, reduce meds, and inspired me to help others reclaim their health through proper nutrition. In a carb-heavy country like India with a 1:834 doctor-patient ratio, this is a game changer. I'm - [The most thorough course in Low Carb Nutrition](https://www.elearning.dlife.in/wdm_course_review/the-most-thorough-course-in-low-carb-nutrition/) - ​The Low Carb Nutrition & Metabolic Health Diploma from dLife.in is a meticulously crafted program that offers an in-depth exploration of human physiology and its intricate relationship with nutrition. This diploma not only imparts theoretical knowledge but also equips learners with practical tools to implement low-carb nutritional strategies effectively. It's a transformative journey that bridges - [A course par excellence](https://www.elearning.dlife.in/wdm_course_review/a-course-par-excellence/) - The DLife Low Carb Nutrition and Metabolic Health Diploma course is meticulously designed and well-structured. It equips the participants to meet the challenges of the low-carb nutritional world head-on. The course ranges from the basics of nutrition to the latest advancements in low-carb nutrition and its amazing results in the remission of metabolic disorders. The - [Feather to my cap](https://www.elearning.dlife.in/wdm_course_review/feather-to-my-cap/) - I liked the portal, its functioning, the knowledge content, the way backend team works, overall it has an amazing learning experience, having served the purpose the diploma will be adding great value to my professional practice as well as my knowledge and learning - [“Empowering, Practical, and Rooted in Science – A Game-Changer for Health Coaches!”](https://www.elearning.dlife.in/wdm_course_review/empowering-practical-and-rooted-in-science-a-game-changer-for-health-coaches/) - I completed the Metabolic Health Diploma from dLife.in and I would like to express my appreciation for the quality and depth of the course. The curriculum is well-structured, evidence-based, and rooted in practical knowledge that is highly applicable for real-world coaching. The strong emphasis on low-carb nutrition, the scientific backing, and the Indian food context - [An eye opener course towards nutrition](https://www.elearning.dlife.in/wdm_course_review/an-eye-opener-course-towards-nutrition/) - This course provides a deep insight into the basics as well as advanced insight into health and nutrition. It helps to understand macros and nutritional wrong doings in our diet. It will help India to reverse its current state of affairs on health. It should be done by anyone and everyone, be it someone looking - [Busting Nutrition Myths with Science: A Course That Truly Delivers](https://www.elearning.dlife.in/wdm_course_review/busting-nutrition-myths-with-science-a-course-that-truly-delivers/) - This course cuts through the noise of fad diets and misinformation, offering science-backed insights into how your body truly works. With a strong focus on insulin resistance and Indian dietary habits, it breaks down complex concepts into practical steps you can apply every day. For me, this is not just a course—it's one of my - [Meticulously drafted and comprehensive course content.](https://www.elearning.dlife.in/wdm_course_review/meticulously-drafted-and-comprehensive-course-content/) - When we think of solutions for Non communicable diseases I.e. lifestyle Disorders or to be precise metabolic diseases . This course has all the answers .And full of scientific insights. According to me every medical Doctor should do this course and get equipped with deep knowledge of Diet and Nutrition ,which is hardly a part - [Before we learn/teach planets, let's learn this!](https://www.elearning.dlife.in/wdm_course_review/before-we-learn-teach-planets-lets-learn-this/) - All of us have a fantasy, can there be just one remedy for almost everything we face? Here it is! It's a way of life which solves almost every problem! dLife mentors are real superheroes! God bless each one of them! - [Your Low Carb Blueprint : Science, Support & Strategy](https://www.elearning.dlife.in/wdm_course_review/your-low-carb-blueprint-science-support-strategy/) - This course is a well-rounded, evidence-based introduction to low carb nutrition. It combines clear scientific explanations, practical tools, and myth-busting insights, with a flexible approach that suits various lifestyles. Standout features include a supportive WhatsApp group, hands-on meal prep guides, and deeper, research-backed content—making it ideal for both beginners and those seeking to deepen their - [An Eye-Opening and a must-take Course for anyone serious about improving own and others health.](https://www.elearning.dlife.in/wdm_course_review/an-eye-opening-and-a-must-take-course-for-anyone-serious-about-improving-own-and-others-health/) - An amazing course for anyone looking to deepen their understanding about nutrition, whether you’re a beginner or have some prior knowledge. The curriculum is incredibly well-organized,covering everything from the basics to advanced and connection dots between commonly faced health issues.Each module has beautiful explanation of concept covered, followed by detailed explanation of how it works - [Gold mine for anyone serious about metabolic health](https://www.elearning.dlife.in/wdm_course_review/gold-mine-for-anyone-serious-about-metabolic-health/) - The content was well organised and each topic is backed by scientific research. Easily one of the best investments you can ever make . What sets this course apart is the forum access , where you can interact with experts - [A complete guide to metabolic health and the amazing intricacy of the human body](https://www.elearning.dlife.in/wdm_course_review/a-complete-guide-to-metabolic-health-and-the-amazing-intricacy-of-the-human-body/) - This course offers a deep, comprehensive look at the one place you can’t escape—your body. From the intricacies of the Krebs cycle to the wonders of human physiology, it reveals the complexity of life and the privilege of sharing this knowledge. Highlights include a cardiovascular surgeon’s journey to better health, a US-returned doctor optimising early - [dLife: Nutrition Secrets for Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/dlife-is-perfect-for-health-and-coaching/) - I took the dLife Low-Carb Nutrition course and loved it. It boosted my LCHF knowledge and confidence to counsel patients with metabolic issues. The content is clear and packed with info on how diet improves health, helping people live pill-free. The dLife forum is awesome, with 10+ years of case studies, expert guidance, and Indian - [Recommend This Course To Everyone](https://www.elearning.dlife.in/wdm_course_review/contents/) - Dlife Metabolic Diploma is a wonderful course for anyone who is looking to be a metabolic coach to treat various lifestyle disorders. It is equipped with the latest studies backed up by science. The community is full of talented people having vast experience in the nutritional world. I recommend Dlife to everyone. - [Nutrition as a way to healthy body, mind and life.](https://www.elearning.dlife.in/wdm_course_review/nutrition-as-a-way-to-healthy-body-mind-and-life/) - dLife course is very well structured. It gave me great joy to go through the material, so much so that I was looking forward to each day in the course. The knowledge one gains along in this path helps to undo and set right many of the wrong misconceptions one has in the world of - [A well rounded course.](https://www.elearning.dlife.in/wdm_course_review/a-well-rounded-course/) - Being aware of metabolic health, I was amazed at how it connected the dots between lifestyle modification, nutrition and chronic diseases. Managing and escaping modern lifestyle diseases is the essence of learning in this course. Useful for absolutely everyone, as health and fitness rely too much on lifestyle as a whole , let alone workout - [Great content and platform to lean about metabolic health, low-carb and ketogenic nutrition](https://www.elearning.dlife.in/wdm_course_review/great-content-and-platform-to-lean-about-metabolic-health-low-carb-and-ketogenic-nutrition/) - A very relevant & systematic content built by dLife.in, in case one really wants to learn about the science of therapeutic carbohydrate restriction, with inputs from the International Experts via their podcasts adding to the learning. Even the learning platform is great, as one has to learn step by step and one just can't skip - [dLife Course: A Dive into Low-Carb Nutrition and Metabolic Mastery](https://www.elearning.dlife.in/wdm_course_review/dlife-course-a-dive-into-low-carb-nutrition-and-metabolic-mastery/) - The dLife course, "Low Carb Nutrition & Metabolic Health Diploma" offered by dLife.in, is a program focused on equipping individuals with in-depth knowledge and practical skills in low-carb, high-fat (LCHF) and ketogenic nutrition. Designed by nutritionists and doctors with real-world experience, the course is well-structured and scientifically backed, emphasizing metabolic health and the reversal of - [A Lifeline for chronic illness remissions.](https://www.elearning.dlife.in/wdm_course_review/a-lifeline-for-chronic-illness-remissions/) - I completed Anup Singh’s DLife Diploma in Low Carb Nutrition and Metabolic Health, and I can’t express how much it has transformed my approach to wellness! As someone always curious about nutrition but overwhelmed by conflicting advice, this course felt like a breath of fresh air. The course’s science-backed approach to LCHF nutrition resonated deeply, - [Real and Measurable Metabolic Health Results, that work every time, because, Science!](https://www.elearning.dlife.in/wdm_course_review/real-and-measurable-metabolic-health-results-that-work-every-time-because-science/) - I joined the course to validate the product design at Artinci, where we make low carb dessert that are keto and diabetic friendly. I met this objective very well, and gained much more too! Improved metabolic health for me and the family was an huge and highly valuable added bonus! - [Highly recommended](https://www.elearning.dlife.in/wdm_course_review/highly-recommended/) - It cleared many myths I used to believe. I have been personally benifited also. I used to have bleeding gums earlier. Now I have no dental issue. Yes, dlife lived up to my expectations. Thank you Anup sir - [Unlock a Health Revolution with Anup Singh’s Masterful DLife Diploma in Low Carb Nutrition!](https://www.elearning.dlife.in/wdm_course_review/unlock-a-health-revolution-with-anup-singhs-masterful-dlife-diploma-in-low-carb-nutrition/) - The DLife Diploma in Low Carb Nutrition and Metabolic Health is a transformative, science-backed course on correct LCHF nutrition, offering clear, practical video lessons on physiology and biochemistry for a pill-free lifestyle. A supportive community with mentors and forums boosts learning. It promotes holistic growth and skills to support loved ones’ health, with real-world strategies - [A must do course to understand metabolic health](https://www.elearning.dlife.in/wdm_course_review/a-must-do-course-to-understand-metabolic-health/) - This D-Life Nutrition Course is an absolute gold mine for anyone looking to deepen their knowledge of metabolic health, especially in the Indian context. The course is structured in a step-by-step manner, making it easy to follow and apply in real life. With the rising concerns around metabolic disorders today, this course is not just - [Outstanding low-carb course](https://www.elearning.dlife.in/wdm_course_review/outstanding-low-carb-course/) - The dLife.in diploma course has been life-changing for me. I have used a low-carb diet in the past to lose weight and maintain it with a lower carbohydrate intake. Getting certified has equipped me with the knowledge to coach many people with metabolic disorders such as obesity, diabetes, PCOS, and more. This enables them to - [A healthy course for a Healthy Nation](https://www.elearning.dlife.in/wdm_course_review/a-healthy-course-for-a-healthy-nation/) - This comprehensive course encompassing all areas of diet to tackle the Chronic Metabolic disorders which are the basis for India's raising unhealthy population is a must one to recommend and spread the word to reach as many people as possible so that a healthy diet like LCHF becomes a REVOLUTION which makes every individual, family - [Dlife low carb high fat nutrition empowering me to embrace a disease free existence.](https://www.elearning.dlife.in/wdm_course_review/dlife-low-carb-high-fat-nutrition-empowering-me-to-embrace-a-disease-free-existence/) - The course content was exceptionally well structured, covering a wide range of relevant topics. the interactive elements such as quiz and videos added a valuable to learning experience. i highly recommend this diploma course to understand LOW CARB HIGH FAT nutrition and provide benefits to others by LCHF professional - [Highly recommend](https://www.elearning.dlife.in/wdm_course_review/highly-recommend/) - The medical world is stuck with the narratives of 80s and benefitting off gullible helpless people diagnosed with some or the other condition. Whereas in Dlife we get to the roots of a condition and get it to remission. Even for a so called healthy person , Dlife is relevant for preventive care . This - [Dlife LCHF Course: A science - backed path to Metabolic Mastery](https://www.elearning.dlife.in/wdm_course_review/dlife-lchf-course-a-science-backed-path-to-metabolic-mastery/) - The Dlife LCHF course is an exceptionally well structured course designed to provide in-depth knowledge about low carb high protein nutrition. Unlike many generic diet courses, this course back its teaching with solid scientific evidence, referencing numerous international publications to ensure credibility. Another major strength of Dlife is it community driven learning environment. The Senior - [LCHF for pill free](https://www.elearning.dlife.in/wdm_course_review/lchf-for-pill-free/) - Each lesson was written in most simplified way so that any body can understand and course had in depth details and after the end of lesson there’s a vedio so i felt both theory and practical,i thought course would be tough but as i started it was soo easy all thanks to Anup,i feel each - [A Course That's A Must For One In Every Family](https://www.elearning.dlife.in/wdm_course_review/a-course-thats-a-must-for-one-in-every-family/) - We took many courses during our formal education over many years. I do not recall any one of them having an immediate impact on our personal lives, whereas in this course, as I progressed, I found many ideas to implement. By the time I completed the course, it had made a huge difference in our - [Best Nutrition Course in India for reversing Metabolic Health disorders..](https://www.elearning.dlife.in/wdm_course_review/best-nutrition-course-in-india-for-reversing-metabolic-health-disorders/) - Highly useful course for me. It really helps me and my mother's health. Dramatic Improvement in health after learning this Course materials. Great comeback in mother's health. All course are well supported with Scientific studies. If anyone wants to take care of self and their family, should definitely join and learn this Course. - [Transformative Learning Experience with the DLife.in Diploma in Low Carb Nutrition and Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/transformative-learning-experience-with-the-dlife-in-diploma-in-low-carb-nutrition-and-metabolic-health/) - The DLife Diploma in Low Carb Nutrition and Metabolic Health is an extensive and informative course. It provides an in-depth understanding of nutrition, covering digestive physiology and metabolic biochemistry. This course has not only expanded my knowledge but also transformed me physically, mentally, and emotionally. It has also made me more aware of those who - [A Course to Master Nutrition for a Lifetime of Wellness](https://www.elearning.dlife.in/wdm_course_review/a-course-to-master-nutrition-for-a-lifetime-of-wellness/) - This Low-Carb High-Fat Nutrition course is truly exceptional and transformative. It offers comprehensive knowledge, practical strategies, and scientific insights that empower you to make lasting improvements to your health and well-being, while also helping those around you lead a pill-free, healthy life. The course not only focuses on the science behind the diet but also - [One-stop solution for anyone seeking to upgrade their health and wellness](https://www.elearning.dlife.in/wdm_course_review/one-stop-solution-for-anyone-seeking-to-upgrade-their-health-and-wellness/) - This comprehensive course is a game-changer, It offers a meticulously designed curriculum with in-depth discussions on key topics, backed by relevant studies. After applying the learnings, I experienced transformative results and enhanced understanding of nutrition and its impact on overall health. I also developed practical skills to support loved ones in achieving their health goals. - [Change your perspective about food!](https://www.elearning.dlife.in/wdm_course_review/change-your-perspective-about-food/) - Right from the early humans to modern day diet(so called pharma/food industry induced diets), It clearly explains how as Humans we need to have our diet, so that we can reduce/reverse most of the chronic diseases which we are facing these days. Why the mainstream media has failed several times in the search of giving - ["Debunks the myths in Metabolic Health"](https://www.elearning.dlife.in/wdm_course_review/debunks-the-myths-in-metabolic-health/) - This course has enhanced my knowledge about metabolic health, debunks all the myths with proof on metabolic health.The information was laid out incredibly well,beautifully presented,expertly written and easy to understand. Its been a rewarding experience gaining the knowledge and the confidence to pay it forward and inspire and educate others on the LCHF path to - [Real Science with scientific evidence. Myth buster. Oasis in the desert for people suffering from metabolic health.](https://www.elearning.dlife.in/wdm_course_review/real-science-with-scientific-evidence-myth-buster-oasis-in-the-desert-for-people-suffering-from-metabolic-health/) - dLife course is like Oasis in desert for people suffering from metabolic health crisis. Based on real evidence based science, course is real game changer in nutrition. Well designed keeping in mind working professionals who can complete in 4 -6 months easily .Fantastic mentors support and access to 2000+ recipes and case studies. - [Connecting the Dots: A Comprehensive Low-Carb Nutrition Course](https://www.elearning.dlife.in/wdm_course_review/connecting-the-dots-a-comprehensive-low-carb-nutrition-course/) - As someone familiar with metabolic health and biochemical processes, I found the dLife course to be a masterclass in connecting the dots. The comprehensive curriculum elegantly woven together concepts I knew, filling gaps and clarifying nuances. I appreciate how dLife: - Bridged theory and practice - Fostered a community of like-minded individuals - Encouraged critical - [Not just a course, but a much needed paradigm shift!](https://www.elearning.dlife.in/wdm_course_review/not-just-a-course-but-a-much-needed-paradigm-shift/) - This isn't just a course, it is a paradigm shift that needs to occur & force multiply, particularly in India, and urgently at that. A must for doctors, medical practitioners, dieticians & nutritionists. Having said that, this is a course for anyone who wants to be healthy and enable the same for their loved ones. - [LCHF Google - DLife :)](https://www.elearning.dlife.in/wdm_course_review/lchf-google-dlife/) - DLife is the only place where you get to learn everything you needed to understand LCHF and it's the only Platform with continues support even after course completion and keep us updated in learnings. - [GAME CHANGER!!](https://www.elearning.dlife.in/wdm_course_review/game-changer/) - This is the only course / forum where the Founders / Instructors have Skin in the Game. They truly practice what they Preach. For me, dLife is a treasure trove, the more I spent time on reading the forum threads, the more I get refined in my understanding about nutrition and health. But what about - [Fabulously Fantastic](https://www.elearning.dlife.in/wdm_course_review/fabulously-fantastic/) - Liked everything, I, took it as a learning and unlearning ground here and still lots to learn. The material compiled meticulously by Anup Singh is phenomenal. Feel like a brand new guy of being more aware and knowing the ABC's of LCHF. A lot of self learning is ongoing process, but feel we have learnt - [Myth buster course](https://www.elearning.dlife.in/wdm_course_review/myth-buster-course/) - Liked to unlearn many things which i was assuming for a long time regarding nutrition. Amazed to read about the internal processes that occur all the time in our body. The course explains how it is possible to remit the prevailing lifestyle diseases like diabetes, obesity, cardiovascular disease and hypertension by making some changes to - [LCHF rocks !](https://www.elearning.dlife.in/wdm_course_review/lchf-rocks/) - Have recently completed the course, and it exceeded my expectations. The course provides step by step approach and understanding of the science behind low-carb nutrition, with clear explanations on how to implement this lifestyle effectively. - [LCHF will save future generation](https://www.elearning.dlife.in/wdm_course_review/lchf-will-save-future-generation/) - Dlife LCHF Course is eye opener for today’s compromised food and pharma industries. Metabolic Health is cause of concern. Even trained doctors need this nutrition coaching. Each and every content is logically proven with data and facts. I took this course with two objectives, to improve my health and my family health and to become - [Best Metabolic Nutrition Course with LCHF philosophy](https://www.elearning.dlife.in/wdm_course_review/excellent-nutrition-course/) - It is a life changing Course, gives in depth details of Root causes of the metabolic issues, gives ability to analyse the issue. Definitely this will give direction and path to lead a chronic free disease life If you are looking for Low Carb nutrition- Search ends here. Gives the capability to build a huge - [Comprehensive learning module](https://www.elearning.dlife.in/wdm_course_review/comprehensive-learning-module/) - The course covers multiple aspects of nutrition science and gives in-depth understanding of nutrition science. All the topics necessary for becoming a metabolic health coach are covered. The forums and recipes are extremely helpful for anyone who has no prior knowledge of nutrition science and experience as a consultant. - [Myth Buster](https://www.elearning.dlife.in/wdm_course_review/myth-buster/) - Backed by "real science" this course has greatly help me unlearn & debunk myths related to food. When you see your health improving you don't want to turn and look back. - [Best Metabolic course one should be study & be aware](https://www.elearning.dlife.in/wdm_course_review/best-metabolic-course-one-should-be-study-be-aware/) - dLife course is one of the finest course helping & guiding individuals to study and make us realize how our body functions, what's good, what doesn't work for one. Kudo's & Appreciate Anup & team putting it together & make it easy for us to study & process the science of nutrition in simplest form. - [A Course That's A Must For Every Doctor & Nutritionist](https://www.elearning.dlife.in/wdm_course_review/a-course-thats-a-must-for-every-doctor-nutritionist/) - Highly recommended for Dietician, Nutritionist and Doctors. This Low Carb Nutrition And Metabolic Health Diploma Course from dlife is the real science backed, myth buster and eye- opener as it unpacks the facts about Nutrition, food what we eat in lieu of that what we are supposed to eat for healthy metabolism and healthy lifestyle. - [To know human as ancestor, energy pathways and supplement section](https://www.elearning.dlife.in/wdm_course_review/to-know-human-as-ancestor-energy-pathways-and-supplement-section/) - I like the course content, easy to understand, written in simple and straight language. It covers all the topics smoothly from basic to advance without giving so much of stress on unimportant things. Has most of the topics required to become a good nutritionist. For me the knowledge was an eye opener, and erased all - [Valuable Knowledge](https://www.elearning.dlife.in/wdm_course_review/valuable-knowledge/) - Liked all course content. Life saving course. Enlightened going through this course. All one of us need to know/gain knowledge for eliminating/reducing their medical problems. - [Invaluable knowledge & learning experience](https://www.elearning.dlife.in/wdm_course_review/invaluable-knowledge-learning-experience/) - The dLife diploma course is designed to be a comprehensive and enriching educational experience. Its self-paced nature allows working professionals to seamlessly integrate learning into their busy schedules. The curriculum is meticulously curated, ensuring that all content is substantiated with factual evidence, providing learners with reliable and actionable knowledge. The unwavering support from senior dLife - [Life Changing Transformation](https://www.elearning.dlife.in/wdm_course_review/life-changing-transformation/) - Dlife LCFH causes has been a blessing in disguise to me and since the day I have been introduced; always got fascinated as why and how the past diseases (Diabetese) were never getting worse. Dlife gave a new life to me and I will spread this to everyone around my community and will build a - [Eye-opener](https://www.elearning.dlife.in/wdm_course_review/eye-opener/) - This kind of course is much needed in the era of fake knowledge spreading all over social media by renowned Nutritionists. - [The marketplace for low carb nutrition - you don't need to be anywhere else](https://www.elearning.dlife.in/wdm_course_review/the-marketplace-for-low-carb-nutrition-you-dont-need-to-be-anywhere-else/) - Already posted a detailed review. - [Deep dive in Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/deep-dive-in-metabolic-health/) - This course is indeed a life changing course. It gives a deep dive in understanding the root causes of metabolic issues and provides actionable tips and strategies to improve metabolic health. It is backed by scientific data, research and evidence. Me and my family's health has improved a lot. I recommend this course to those - [Low carb nutrition and metabolic health is the most important course of the current era](https://www.elearning.dlife.in/wdm_course_review/low-carb-nutrition-and-metabolic-health-is-the-most-important-course-of-the-current-era/) - This course is very important and very helpful to all people. If we want to prevent the spread of chronic disease in the current society, this course is very helpful. - [Science backed course](https://www.elearning.dlife.in/wdm_course_review/science-backed-course-2/) - This course is a myth buster. It unpacks the science behind what we eat and clears up myths about nutrition. This course is informative, well structured, and engaging with excellent material and resources. From start to finish, this course captivates with its depth of knowledge and can be easily grasped by even from non medical - [The Future](https://www.elearning.dlife.in/wdm_course_review/the-future/) - As per the expectations the course is easy to understand with more scientific evidence that gives conviction on Keto/LCHF. Course has arranged in a sequence ie known to unknown. its add lots of value to capability on Medical Science. Heartfelt thanks to you - [This course clears most of the diet & nutrition myths.](https://www.elearning.dlife.in/wdm_course_review/this-course-clears-most-of-the-diet-nutrition-myths/) - The entire course was a great learning time. It has a potential to change your life style completely. It gives you the kind of knowledge that's going to stay with you life long. The myths about nutrition & diets created by main stream media gets washed by this course. This course gives us the freedom - [The most important learning from this course is a common man can take care of his health with the knowledge on nutrition.](https://www.elearning.dlife.in/wdm_course_review/the-most-important-learning-from-this-course-is-a-common-man-can-take-care-of-his-health-with-the-knowledge-on-nutrition/) - I thoroughly enjoyed every module of the course. Made my own notes and took time to digest the science of low carb nutrition. Our family health is in our hands. We should not rely on doctors every now and then unless it is an emergency. Prevention is always better than cure. So, I recommend at - [Visual and easy flow content of LCHF](https://www.elearning.dlife.in/wdm_course_review/visual-and-easy-flow-content-of-lchf/) - Lot of visual content including critical videos from global subject matter experts on all the LCHF topics. Great overall platform to launch oneself to certify and gain the nutrition diploma for a changing world order in nutrition. Tools of forum interaction, thousands of recipe access, mentor support and view exchanges and regular updation through whatsapp - [LCHF seekers, ponder no more. dLife it is!](https://www.elearning.dlife.in/wdm_course_review/lchf-seekers-ponder-no-more-dlife-it-is/) - What I loved about the course was its Indian context and the meticulousness of the study material. There are lot of LCHF courses/resources available on the internet and while they all have something to offer, they miss the Indian perspective. Studying this course has been a very informative and entertaining journey for me. Every aspect - [Evidence-based well researched extensive course](https://www.elearning.dlife.in/wdm_course_review/evidence-based-well-researched-extensive-course/) - This course is very extensive and has covered almost every aspect of nutrition in lay language. The videos added in the course are cherry of the cake. They are so informative and helpful, they have busted a lot of myths around nutrition. I feel at least one person from every family must have adequate knowledge - ["Unlocking Metabolic Health"](https://www.elearning.dlife.in/wdm_course_review/unlocking-metabolic-health/) - The course is excellent and meticulously designed The course is not just theoretical but provides hands -on knowledge that can be directly applied to real-life scenarios. It is commendable , balancing theory with practical application and the support provided throughout the journey was outstanding. - [Profound experience](https://www.elearning.dlife.in/wdm_course_review/profound-experience/) - Completing the 6-month diploma course with dLife has been nothing short of life-changing. The course equipped me with profound knowledge and practical tools to tackle diabetes and various metabolic disorders head-on. What I found most remarkable is how it empowered me to not only transform my own health but also bring about a significant positive - [Everyone should take this course for enlightenment and a healthy lifestyle.](https://www.elearning.dlife.in/wdm_course_review/everyone-should-take-this-course-for-enlightenment-and-a-healthy-lifestyle/) - I completed the dLife LCHF Diploma course and was thoroughly impressed. The course was informative, well-structured, and engaging, with excellent materials and supportive feedback. It greatly improved my understanding of nutrition and empowered me to make healthier choices. Highly recommended for anyone interested in bettering their diet or pursuing a career as a certified metabolic - [It's not a course, it's a "HEALING POTION"](https://www.elearning.dlife.in/wdm_course_review/its-not-a-course-its-a-healing-potion/) - It's not a course, it”s a “LIFETIME HEALING POTION" which will teach you in a very well-structured way, how to be metabolically and overall healthy just by incorporating the lifetime sustainable "LOW CARB HIGH FAT" diet into your daily routine!! So, would highly recommend each one to grab this opportunity of ingesting this "LIFETIME HEALING - [From Novice to Knowledgeable: My Enlightening Journey Through the DLife Diploma](https://www.elearning.dlife.in/wdm_course_review/from-novice-to-knowledgeable-my-enlightening-journey-through-the-dlife-diploma/) - When I signed this Diploma, I wasn't sure what to expect. I’d tried low-carb and keto diets before but wanted a deeper understanding. The course started with the basics, making complex topics like the endocrine system easy to understand. Quizzes tested my knowledge, making me feel like I was back in school in a good - [This course is PRACTICAL !](https://www.elearning.dlife.in/wdm_course_review/this-course-is-practical/) - This is the most practical of any courses I did so far! each and every step of the course equips you with knowledge which you can immediately apply on yourselves or others and others and get excellent health benefits without compromising on anything! In this era of lifestyle disorders and ever increasing co morbidities with - [Atleast one should learn this course in their Family](https://www.elearning.dlife.in/wdm_course_review/atleast-one-should-learn-this-course-in-their-family/) - This Course is well structured and people will help us more than money, age is not limit here, they teach us life lesson to eat right, to be healthy ,to be active and regular updates will be posted in forum and its a life-long learning journey like magazine we can read it daily and if - [This course will add life to the number of years we live](https://www.elearning.dlife.in/wdm_course_review/this-course-will-add-life-to-the-number-of-years-we-live/) - This course is a complete, authentic, enriching and an academic marvel. The content is too deep, the reference materials provided under each chapter is huge. If there is any one course that can make health better is this course. This is self sustaining, mathematically formulated and scientific in its approach. I call it as quantization - [Enriching Learning](https://www.elearning.dlife.in/wdm_course_review/enriching-learning/) - I am quite satisfied and extremely glad to have done this course. My keen interest in nutrition, fitness led me to enrolling myself in this course. At the culmination of the course I have been enriched by the learnings. I am at a much better understanding level with respect to basic and fundamentals of good - [A Well-Written Nutrition Course](https://www.elearning.dlife.in/wdm_course_review/a-well-written-nutrition-course/) - The course is exhaustive & well-written which has helped me learn important concepts about nutrition & metabolism. - [A comprehensive low-carb nutrition course](https://www.elearning.dlife.in/wdm_course_review/a-comprehensive-low-carb-nutrition-course/) - I enjoyed studying this comprehensive and detailed course on metabolic health and low-carb nutrition. As a low-carb nutrition enthusiast, I was looking for a formal understanding of how to adopt a low-carb nutrition lifestyle. This course provided me with a solid foundation of theoretical knowledge as well as practical guidance about low-carb. I have also - [Discover the Science of Health](https://www.elearning.dlife.in/wdm_course_review/discover-the-science-of-health/) - The Low Carb Nutrition and Metabolic Health Diploma course offers a transformative journey into the realm of nutrition and wellness. From start to finish, this course captivates with its depth of knowledge, practical applications, and expert instruction. What sets this course apart is its comprehensive approach to low-carbohydrate nutrition and metabolic health. Each module is - [Scientific and path-breaking course in metabolic health space!](https://www.elearning.dlife.in/wdm_course_review/a-game-changer-in-metabolic-health-space/) - As the metabolic health of the general population is deteriorating with every passing day, dlife.in platform is going to stand tall to tackle it. The course content is well structured and can be easily grasped by people from non-medical fields. It has comprehensive list of topics covering till the most recent researched topics in metabolic - [India ‘ s best and only low carb nutrition course](https://www.elearning.dlife.in/wdm_course_review/india-s-best-and-only-low-carb-nutrition-course/) - Greetings ! DLife is India’s best and only low carb nutrition platform. Thank you to the entire team. Dlife is doing an amazing job to fight and provide awareness regarding metabolic health. Keep up the good work. wanted to take a moment to express my sincere gratitude for your thoughtfulness. Your kind gesture has truly - [Best Course for Health and Nutrition](https://www.elearning.dlife.in/wdm_course_review/best-course-for-health-and-nutrition/) - This course is top quality course. This course is very informative and is key to improving one's health. This course have help me with knowledge of nutrition and make better choices for balanced and healthy life style. I would recommend if anyone wants to be low carb coach this one is the best. - [One-stop resource!](https://www.elearning.dlife.in/wdm_course_review/one-stop-resource/) - After years of struggling to navigate the complexities of nutrition and health management, this course provided a much-needed one-stop resource filled with science-backed information. It was refreshing to get invaluable insights and tools that dispelled common misconceptions, empowering me with evidence-based knowledge to guide myself and others towards optimal health. I wholeheartedly recommend this course - [Need Q and A session](https://www.elearning.dlife.in/wdm_course_review/need-q-and-a-session/) - The course was very comprehensive and insightful. It only has recorded lessons. Live lectures and Q & A sessions would be very helpful. - [A Game-Changer in Metabolic Health Education: My Experience with d'Life's Diploma Program](https://www.elearning.dlife.in/wdm_course_review/a-game-changer-in-metabolic-health-education-my-experience-with-dlifes-diploma-program/) - After completing nutrition courses at respected fitness schools, I joined d'Life's Diploma in Metabolic Health seeking deeper insights. From day one, the welcoming environment affirmed I was in the right place. d'Life's dedication to extensive research in metabolic health is unparalleled. The course exceeded my expectations, providing comprehensive knowledge and practical skills. I now feel - [This is the best course on Nutrition](https://www.elearning.dlife.in/wdm_course_review/this-is-the-best-course-on-nutrition/) - I liked very much the exhaustively curated content, very well structured. It is very apparent lot of research and efforts went in to create such a comprehensive and in depth content. The external links to videos and research material is very helpful. It’s a completely packed content leaving almost nothing. The course structure is very - [Comprehensive and High Quality](https://www.elearning.dlife.in/wdm_course_review/comprehensive-and-high-quality/) - This is no accident. The course is so comprehensive and the content is so high quality and so carefully curated, leaving nothing out - simply brilliant. The minds behind putting this all together, led by Anup, have delivered an unparalleled, enviable product. Truly transforming lives! - [This course is the answer to the “ Need of the hour”](https://www.elearning.dlife.in/wdm_course_review/this-course-is-the-answer-to-the-need-of-the-hour/) - This course was amazing from the start to end ! Course content is well curated . Links, Proofs and References open your eyes to a whole new world of health and wellness , one wonders why “this” was not the conventional wisdom our health providers were taught! Now that this enlightenment is available to us - [Metabolic issues in Human life](https://www.elearning.dlife.in/wdm_course_review/metabolic-issues-in-human-life/) - People at Dlife are Great mentors, hungry to help you to guide you throughout the study period and its like a family tree where one can grow.......Sky is the limit at D life - [This course will leave you sufficiently in control of your own health.](https://www.elearning.dlife.in/wdm_course_review/this-course-will-leave-you-sufficiently-in-control-of-your-own-health/) - I liked the course content which is explained in easy terms but is sufficiently deep to cover important topics. Completing this course gives one a holistic view of the issues in metabolic health and the ability to handle it with lifestyle changes. - [Life changing program for sure.](https://www.elearning.dlife.in/wdm_course_review/life-changing-program-for-sure/) - Being a Vegetarian I had not realised the importance of Protein and fats in my life till I joined this course.. This course is lucid, practical, very much useful and can be implimented by anybody irrespective of Being a vegetarian or non Vegetarian. After joining this program, my family's diet is totally changed.. being vegetarians - [Ideal guide to learn all there is to know on Nutrition & Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/ideal-guide-to-learn-all-there-is-to-know-on-nutrition-metabolic-health/) - The course is well structured, & will make sense to a beginner even & has a lot to offer to medical professionals also. The modules cover the basics of nutrition, specific diseases, diets, exercises & all that one needs to know to improve their own & others health. On completion one has access to support - [Best nutritional course for all medicos and nutritionists.](https://www.elearning.dlife.in/wdm_course_review/best-nutritional-course-for-all-medicos-and-nutritionists/) - A very comprehensive nutritional course integrating scientific principles and practical strategies to effectively combat and reverse metabolic disorders. Adding value to your life and people around. The D.life course, community and MHC have provided invaluable insights and fostered engaging discussions that have enriched my understanding of nutrition. The depth of knowledge shared by members is - [Good Course on Low Carb Nutrition](https://www.elearning.dlife.in/wdm_course_review/good-course-on-low-carb-nutrition/) - This course was very helpful in advancing my understanding of the human body & nutrition. - [Want better health for self and community join Dlife LCHF course](https://www.elearning.dlife.in/wdm_course_review/want-better-health-for-self-and-community-join-dlife-lchf-course/) - It has met more than my expectations of a LCHF certification that too in Indian Context . Highly recommend Dlife Programmes - [Best nutrition course - low carb Nutrition to reverse all metabolic diseases](https://www.elearning.dlife.in/wdm_course_review/best-nutrition-course-low-carb-nutrition-to-reverse-all-metabolic-diseases/) - Enrolling in the low carb Nutrition course was one of the best decisions I have ever made. journey would not only equip me with knowledge and skills but also touch my heart in the most profound way.The course was thoughtfully designed,covering a wide range of topics,from the basics of nutrition to advanced concepts in dietetics. - [Get to the root of your diabetes & take control](https://www.elearning.dlife.in/wdm_course_review/get-to-the-root-of-your-diabetes-take-control/) - Amazing course that gives you real scientific knowledge on what is happening in your body if you are diabetic (or have cholestrol, BP, PCOS, Fatty Liver issues) and why you got them in the first place. I enjoyed learning how we can leverage food to take control and solve these challenges. A THOROUGH course indeed! - [One of its kind nutrition course](https://www.elearning.dlife.in/wdm_course_review/one-of-its-kind-nutrition-course/) - A very comprehensive and exhaustive course material. it covers all the aspects of nutrition. I am able to understand lot of myths of nutrition, what to eat and what not to eat. I have started experimenting on myself. I am seeing lot of improvements. I would suggest this course anyone looking for nutrition courses. Even - [All in one solution !](https://www.elearning.dlife.in/wdm_course_review/all-in-one-solution/) - I really found The low carb nutrition and metabolic health course insightful, helpful and a huge eye opener. All the topics are covered in a simple way where anybody can understand. All the facts are discussed topic wise. This is the only platform where the facts are discussed and shown that , Just by lowering - [Sad Reality of Unhealthy Diet Practiced by Masses Considering it HEALTHY](https://www.elearning.dlife.in/wdm_course_review/sad-reality-of-unhealthy-diet-practiced-by-masses-considering-it-healthy/) - The efforts, podcasts, interactions on the group are worth appreciating. The never-ending support held out to the members, enabled us to complete this course . As expected at the initial stage of this spectacular course, I now carry a chest of treasure as I walk out of this amazing platform. - [The ONLY metabolic heath and nutrition course you need.](https://www.elearning.dlife.in/wdm_course_review/the-only-metabolic-heath-and-nutrition-course-you-need/) - There is none better. In fact, there is none like it. If you want tackle metabolic syndrome which is a silent pandemic in India and across the world and no one speaks about it, this is it. Look no further. - [Transformative Experience !](https://www.elearning.dlife.in/wdm_course_review/transformative-experience/) - I recently completed the low-carb nutrition program, and I must say, I am thoroughly impressed with the experience. The course was comprehensive and exhaustive, covering all aspects of low-carb eating, from the science behind it to practical tips for implementation. Overall, I highly recommend this low-carb nutrition program to anyone looking to improve their health - [An enlightening experience with dlife.in !!](https://www.elearning.dlife.in/wdm_course_review/an-enlightening-experience-with-dlife-in/) - I recently completed a transformative Nutrition course from dLife.in, highlighting the benefits of a low-carb, high-fat diet in combating lifestyle disorders. The course, enriched with updated research articles, fostered interactive learning between mentors and learners. The practical internship provided hands-on training, boosting my confidence. Permanent access to course content ensures ongoing learning. Overall, dLife.in's course - [The Absolute Gold-Standard Course In Low-Carb Nutrition & Metabolic Health!](https://www.elearning.dlife.in/wdm_course_review/the-absolute-gold-standard-course-in-low-carb-nutrition-metabolic-health/) - This course is the outcome of Anup’s personal tryst w/ T2D & the brilliant subsequent revolution he created in Indian LCHF space & metabolic health! The sheer genius of the course is in the way it has been written, structured & resourced. With 800+ ref & 68 videos, in all, there’s just nothing in “LC - [Best nutrition course](https://www.elearning.dlife.in/wdm_course_review/best-nutrition-course/) - Joining DLife's low carb nutrition course was one of the best decision I have taken in 2023. It is very comprehensive and also very well structured program . DLife community is very proactive to respond to all the queries one might have. I have applied the principles of low carb on my own PCOD condition - [Absolutely different and valuable approach towards better health.](https://www.elearning.dlife.in/wdm_course_review/absolutely-different-and-valuable-approach-towards-better-health/) - 5 star review for this course would be less,no words to express how blessed & thankful I am,unique & purely life changing course,can be done at our pace & comfort zone. In depth material available to study,videos pdfs.Mentors,seniors are so kind & supportive to guide at every step during course & even after that in - [Treasure Trove of Invaluable Knowledge](https://www.elearning.dlife.in/wdm_course_review/treasure-trove-of-invaluable-knowledge/) - The course content is well developed and makes you ready to become a low-carb health coach to heal yourself or heal others! - [World Class course in Low Carb Nutrition!](https://www.elearning.dlife.in/wdm_course_review/world-class-course-in-low-carb-nutrition/) - dLife Low Carb Nutrition & Metabolic Health diploma is hands down the best Nutrition course in India. Having done a few course before this, I can say this with full confidence. The content is top notch & the structuring of the course is too good. This is one of the best courses in Low Carb - [Comprehensive Metabolic Health Overview](https://www.elearning.dlife.in/wdm_course_review/comprehensive-metabolic-health-overview/) - Very exhaustive course. Easy to understand, even for people not having biology/science background to learn about metabolism and metabolic health. Added advantage is the access to articles and research papers that is an ocean of information about the field of nutrition, metabolic health and progress made and being made in the field. it helps in - [Nutrition Science and dLife is synonymous. Do not miss this course](https://www.elearning.dlife.in/wdm_course_review/nutrition-science-and-dlife-is-synonymous-do-not-miss-this-course/) - Simple is NOT easy! dLife diploma course does both. Simplifies the science to understand and the interface, flow of topics makes it easy to track, absorb and immerse. Definitely a one of a kind platform. - [LCHF nutrition](https://www.elearning.dlife.in/wdm_course_review/lchf-nutrition/) - The course was well-paced and detailed. - [Think Nutrition Course. Think dLife.in! 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Enrolling offers a rewarding - [First of Its Kind CPDSCO UK Accredited Comprehensive Low Carb Nutrition and Metabolic Health Diploma](https://www.elearning.dlife.in/wdm_course_review/first-of-its-kind-cpdsco-uk-accredited-comprehensive-low-carb-nutrition-and-metabolic-health-diploma/) - I recently completed the Low Carb Nutrition Diploma offered by dlife.in and I am thrilled to share my positive experience with this comprehensive program. dlife's diploma course surpassed my expectations in terms of depth and breadth ,covering everything from the science behind low-carb nutrition to practical applications, the curriculum provided a solid foundation for understanding - [Dlife Low Carb Nutrition Journey- An Invaluable Learning Jouney](https://www.elearning.dlife.in/wdm_course_review/dlife-low-carb-nutrition-journey-an-invaluable-learning-jouney/) - I'm so happy to share that this, I learned so much about Low Carb Nutrition and metabolic health that i never knew before. The course was really detailed, covering all the basics and even more aspects of subject. I would 100% recommend this course to everyone. Thank You Arun sir & Team. Thank You DLIFE!! - [Thorough, well structured, comprehensive, life-changing course](https://www.elearning.dlife.in/wdm_course_review/thorough-well-structured-comprehensive-life-changing-course/) - This course provides thorough, well-structured and comprehensive knowledge about nutrition and metabolic health in general. Every detail in the content, including the selection of videos is done thoughtfully for the benefit of the learner. The content build up is methodical and gradual - from basics to advanced - which makes it easy for even someone - [Exclusive Low Carb Nutrition Course](https://www.elearning.dlife.in/wdm_course_review/exclusive-low-carb-nutrition-course/) - This comprehensive course encompasses all aspects of LCHF (Low Carb High Fat) and low-carb diets. 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Whether you're a beginner or - [One of the best Lowcarb Nurition course](https://www.elearning.dlife.in/wdm_course_review/one-of-the-best-lowcarb-nurition-course/) - The course content was exceptionally well-structured, covering a wide range of relevant topics. The modules were clear, concise, and presented in a way that made complex concepts easy to understand. The interactive elements, such as quizzes and videos, added a valuable hands-on dimension to the learning experience. Thank you Dlife. - [Good & Comprehensive course.](https://www.elearning.dlife.in/wdm_course_review/good-comprehensive-course/) - Structured well with appropriate videos for better understanding. - [DLife Low Carb Nutrition Course - An Invaluable Learning Journey](https://www.elearning.dlife.in/wdm_course_review/dlife-low-carb-nutrition-course-an-invaluable-learning-journey/) - I'm so happy to share that this course exceeded all of my expectations! The team and moderators were incredibly supportive, and the content was comprehensive. I learned so much about low carb nutrition and metabolic health that I never knew before. The course was really detailed, covering all the basics and even the more complex - [Reasearch and Development of Highest Levels](https://www.elearning.dlife.in/wdm_course_review/reasearch-and-development-of-highest-levels/) - I took the DLife Low Carb Nutrition Course for my self gain and understanding of how a low carb diet could scientifically lower my chances of getting a high BP or diabetes. I deep delved into the course page after page and chapter after chapter to learn the science behind how our bodies turn out - [A must do course for everyone who is serious about Low Carb Nutrition](https://www.elearning.dlife.in/wdm_course_review/a-must-do-course-for-everyone-who-is-serious-about-low-carb-nutrition/) - This diploma is an exceptionally well designed course for everyone including people with no background in the science of nutrition. It equips you with both the technical knowledge and coaching skills that is practical and implementable. 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All the information is provided in a very organized - [A Heartfelt Testimonial for the Exceptional KETO Course](https://www.elearning.dlife.in/wdm_course_review/a-heartfelt-testimonial-for-the-exceptional-keto-course/) - I'm incredibly grateful for the comprehensive KETO course provided by DLIFE. It covered every detail, equipping me with the right knowledge to help clients with their lifestyle issues. The practical approach were impressive. This course has positively impacted my professional journey, boosting my confidence and credibility. The supportive community enhanced the overall learning experience. Thank - [The Best Course on Nutrition & Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/the-best-course-on-nutrition-metabolic-health/) - Nutrition is the key to real health. There is decades worth of mis- and dis-information about it! Then comes a comprehensive, exhaustive, and in-depth course like no other- DLife Diploma in Nutrition. 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For any one...Living from context of 'healthy eating' will - [A must do for all fitness and health coaches](https://www.elearning.dlife.in/wdm_course_review/a-must-do-for-all-fitness-and-health-coaches/) - As a fitness enthusiast constantly seeking ways to optimize my health and fitness goals, this course provided valuable insights and strategies for achieving sustainable health goals. This course can be a game changer in the approach towards nutrition and overall well being. The course lays a strong foundation of knowledge regarding all macros and their - [Correct and Exact Knowledge about Nutrition Science.](https://www.elearning.dlife.in/wdm_course_review/correct-and-exact-knowledge-about-nutrition-science/) - This is just the best course. To what I was looking for. Thankyou d.life for existing. 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Low Carb can - [Say Goodbye to energy crashes, food cravings & Metabolic disorders , and Welcome Healthier You.](https://www.elearning.dlife.in/wdm_course_review/say-goodbye-to-energy-crashes-food-cravings-metabolic-disorders-and-welcome-healthier-you/) - I recently completed the Low Carb Diploma program, and I must say it was an incredible experience. This program exceeded all my expectations and provided me with a comprehensive understanding of low-carb nutrition and its benefits. I highly recommend it to anyone interested in improving their health and well-being. First and foremost, the program's content - [A top quality low carb nutrition course](https://www.elearning.dlife.in/wdm_course_review/a-top-quality-low-carb-nutrition-course/) - A perfect course for the ones who are eager to learn about low-carb nutrition. 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The simplicity..... referral to many studies.... links to the YouTube videos at the right context. otherwise, they are anyway available in YouTube to watch. but the general habit, we fast forward after watching few minutes. here due to the mandatory requirement, I focussed and - [The Best & Most Practical to Indian context course](https://www.elearning.dlife.in/wdm_course_review/the-best-most-practical-to-indian-context-course/) - I have gained valuable knowledge and skills that will benefit my clients, my brand & myself. The course does a deep dive into the science behind Low-Carb. The practical way in which we can understand the problems faced by Indian clients when implementing low carb nutrition is especially impressive. It is very easy to apply - [An Excellent Course In Low Carb Nutrition](https://www.elearning.dlife.in/wdm_course_review/an-excellent-course-in-low-carb-nutrition/) - dLife six-month low-carb nutrition course is of the most comprehensive, exhaustive courses on low-carb nutrition. After completion of this course that offers up-to-date knowledge on healthy nutrition, there is a surge in confidence in handling clients. This course’s step-by-step, detailed explanation of every aspect of a low-carb lifestyle is a treasure for anyone looking to - [The Best way to thrive with perfect Metabolic Health](https://www.elearning.dlife.in/wdm_course_review/the-best-way-to-thrive-with-perfect-metabolic-health/) - All expectations met. The most comprehensive course on nutrition and metabolic health. - [The Only Low Carb Nutrition Diploma Course In India](https://www.elearning.dlife.in/wdm_course_review/the-only-low-carb-nutrition-diploma-course-in-india/) - This low-carb nutrition course is quite comprehensive with updated research studies and information. I really like the way it is compiled – into relevant chapters, easy to comprehend and absorb. Several enriching videos by reputed speakers make it engaging and interesting. It fully equips you with the required knowledge on how food closely impacts your - [The best diploma course in lowcarb space & to be attended by as many individuals as possible.](https://www.elearning.dlife.in/wdm_course_review/the-best-diploma-course-in-lowcarb-space-to-be-attended-by-as-many-individuals-as-possible/) - Highest level course even at the global level owing to: 1. Very elaborate Syllabus touching all essential aspects of nutrition, metabolic & related diseases 2. dLife.in website is very well structured & organized 3. eLearning courseware is one of the most immaculate & perfect for attending in an online manner – completely hassle free 4. - [Best Low Carb Nutrition Diploma course in India.](https://www.elearning.dlife.in/wdm_course_review/best-low-carb-nutrition-diploma-course-in-india/) - Well designed, exhaustive, loaded with numerous scientific studies and videos make the course easy to understand. All human physiological aspects are covered nicely. It also deals with various metabolic disorders and causes. The course also gives a good understanding of macro and micronutrients, vitamins, minerals, and many more. The internship is an added boon. I - [A Low Carb Nutrition Course that I would certainly recommend.](https://www.elearning.dlife.in/wdm_course_review/a-low-carb-nutrition-course-that-i-would-certainly-recommend/) - Would definitely recommend this course to everybody who is interested in taking care of their health. There is so much scientific knowledge and references in this course. I am very thankful to be introduced to this world of right nutrition - [Excellent and Fully Loaded Course!!!](https://www.elearning.dlife.in/wdm_course_review/excellent-and-fully-loaded-course/) - It's not only a course for a low-carb diet, it’s also great for people who want to transition into a health-related field and looking for certification. The course includes so many new aspects including science-based evidence, internship, interaction in dLife forum and so on which builds confidence. I highly recommend this course for anyone looking to take their passion for - [Wholistic Approach to Nutrition & Health](https://www.elearning.dlife.in/wdm_course_review/wholistic-approach-to-nutrition-health/) - A lot of thought has been put in designing this course. I am very confident now with the insight, information and knowledge that i have gained through this course, to train and help people to improve their health. I recommend this course to each and every one who is looking to take course in nutrition - [Superb course on low carb nutrition with all theoretical and practical aspects.](https://www.elearning.dlife.in/wdm_course_review/superb-course-on-low-carb-nutrition-with-all-theoretical-and-practical-aspects/) - The course is designed extremely well and have covered almost all the physiological aspects to build a strong foundation. I think if someone do this course with dedication and commitment will definitely acquire more knowledge than any dietitian or nutritionist. Interaction with people through forum as a part of internship helped a lot to build - [An excellent understanding of basic nutrition](https://www.elearning.dlife.in/wdm_course_review/an-excellent-understanding-of-basic-nutrition/) - One of the best aspects of the course is that a person is not required to study 5years of nutrition to understand or help others on Low Carb. It gives an in-depth insight into practical nutritional guidelines. From an Indian context, this is good for someone who wants to have a valid diploma to practice - [Great Low Carb Nutrition Diploma Course In India](https://www.elearning.dlife.in/wdm_course_review/great-low-carb-nutrition-diploma-course-in-india/) - This is a very exhaustive & informative Low Carb Nutrition Course. We get to learn the basics of real human nutrition. In addition, we also learn the root causes of all modern chronic diseases and how to address the same through nutrition. The best part is the internship in the forum. 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